Digoxin and Rilpivirine interaction

Digoxin and Rilpivirine: the Rilpivirine prescribing label reports no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Rilpivirine (EDURANT) label · effective 2025-08-28

No interaction

Rilpivirine did not have a clinically significant effect on the pharmacokinetics of digoxin or metformin.

Drug interactionsnames DigoxinView label on DailyMed

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Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.