Digoxin and Teriparatide interaction
Digoxin and Teriparatide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Digoxin label · effective 2025-04-10
Parathyroid Hormone Analog Teriparatide Sporadic case reports have suggested that hypercalcemia may predispose patients to digitalis toxicity.
Teriparatide transiently increases serum calcium.
Use in Thyroid Disorders and Hypermetabolic States Hypothyroidism may reduce the requirements for digoxin.
Thyroid Supplement Thyroid Treatment of hypothyroidism in patients taking digoxin may increase the dose requirements of digoxin.
Digoxin responses are normal in patients with compensated thyroid disease.
From the Teriparatide (Forteo) label · effective 2026-08-03
Risk of Digoxin Toxicity Hypercalcemia may predispose patients to digitalis toxicity because FORTEO transiently increases serum calcium.
Consider the potential onset of signs and symptoms of digitalis toxicity when FORTEO is used in patients receiving digoxin [see Drug Interactions ( 7.1 ) and Clinical Pharmacology ( 12.3 )].
Digoxin: Transient hypercalcemia may predispose patients to digitalis toxicity ( 5.6 , 7.1 )
Digoxin Sporadic case reports have suggested that hypercalcemia may predispose patients to digitalis toxicity.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.