Doxycycline and Etonogestrel and ethinyl estradiol interaction
Doxycycline and Etonogestrel and ethinyl estradiol: both prescribing labels mention this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Doxycycline (Doxycycline Hyclate) label · effective 2026-06-30
Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective.
Oral Contraceptives Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective.
From the Etonogestrel and ethinyl estradiol (Etonogestrel/Ethinyl Estradiol) label · effective 2025-02-26
The serum concentrations of etonogestrel and ethinyl estradiol were not affected by concomitant administration of oral amoxicillin or doxycycline in standard dosages during 10 days of antibiotic treatment.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.