Doxycycline and Medroxyprogesterone interaction

Doxycycline and Medroxyprogesterone: the Doxycycline prescribing label mention this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Doxycycline (Doxycycline Hyclate) label · effective 2026-06-30

Minor

Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective.

Drug interactionsby drug classView label on DailyMed
Minor

Oral Contraceptives Concurrent use of tetracyclines, including doxycycline hyclate may render oral contraceptives less effective.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.