Droperidol and Nortriptyline interaction

Droperidol and Nortriptyline: the Droperidol prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Droperidol label · effective 2023-03-20

Moderate

Possible pharmacodynamic interactions can occur between droperidol and potentially arrhythmogenic agents such as class I or III antiarrhythmics, antihistamines that prolong the QT interval, antimalarials, calcium channel blockers, neuroleptics that prolong the QT interval, and antidepressants.

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Moderate

Following the administration of droperidol, the dose of other CNS depressant drugs should be reduced.

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Minor

As with other CNS depressant drugs, patients who have received droperidol should have appropriate surveillance.

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Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.