Duloxetine and Fluticasone and salmeterol interaction

Duloxetine and Fluticasone and salmeterol: the Fluticasone and salmeterol prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Fluticasone and salmeterol (Fluticasone Propionate and Salmeterol) label · effective 2025-08-21

Moderate

Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution.

Drug interactionsby drug classView label on DailyMed
Moderate

Monoamine Oxidase Inhibitors and Tricyclic Antidepressants Fluticasone Propionate/Salmeterol MDPI should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, because the action of salmeterol, a component of this product, on the vascular…

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.