Enalaprilat and Methyldopa interaction

Enalaprilat and Methyldopa: both prescribing labels mention this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Methyldopa label · effective 2025-03-28

Minor

Drug Interactions When methyldopa is used with other antihypertensive drugs, potentiation of antihypertensive effect may occur.

Drug interactionsby drug classView label on DailyMed

From the Enalaprilat label · effective 2024-01-04

Minor

Other Cardiovascular Agents Enalaprilat injection, USP has been used concomitantly with digitalis, beta adrenergic-blocking agents, methyldopa, nitrates, calcium-blocking agents, hydralazine and prazosin without evidence of clinically significant adverse interactions.

Drug interactionsnames MethyldopaView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.