Entacapone and Rasagiline interaction

Entacapone and Rasagiline: the Entacapone prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Entacapone label · effective 2019-03-14

Minor

It is theoretically possible, therefore, that the combination of Entacapone Tablets and a non-selective MAO inhibitor (e.g., phenelzine and tranylcypromine) would result in inhibition of the majority of the pathways responsible for normal catecholamine metabolism.

Warningsby drug classView label on DailyMed
Minor

For this reason, patients should ordinarily not be treated concomitantly with Entacapone Tablets and a non-selective MAO inhibitor.

Warningsby drug classView label on DailyMed
Minor

Effect of Entacapone on the Metabolism of Other Drugs See WARNINGS regarding concomitant use of Entacapone Tablets and non-selective MAO inhibitors.

Precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.