Ergotamine and caffeine and Theophylline interaction

Ergotamine and caffeine and Theophylline: the Theophylline prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Theophylline label · effective 2026-01-29

Minor

Other xanthines such as caffeine, dyphylline, and pentoxifylline are not detected by these assays.

Drug interactionsnames Ergotamine and caffeineView label on DailyMed
Minor

Caffeine and xanthine metabolites in neonates or patients with renal dysfunction may cause the reading from some dry reagent office methods to be higher than the actual serum theophylline concentration.

Drug interactionsnames Ergotamine and caffeineView label on DailyMed
Minor

The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific for theophylline.

Drug interactionsby drug classView label on DailyMed
No interaction

…albuterol, systemic and inhaled mebendazole amoxicillin medroxyprogesterone ampicillin, with or without methylprednisolone sulbactam metronidazole atenolol metoprolol azithromycin nadolol caffeine, dietary ingestion nifedipine cefaclor nizatidine co-trimoxazole (trimethoprim and sulfamethoxazole) norfloxacin ofloxacin diltiazem omeprazole dirithromycin prednisone, prednisolone…

Drug interactionsnames Ergotamine and caffeineView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.