Erythromycin and Gefitinib interaction
Erythromycin and Gefitinib: the Gefitinib prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Gefitinib (IRESSA) label · effective 2023-02-28
• CYP3A4 Inhibitor: Monitor adverse reactions if concomitant use with IRESSA.
CYP3A4 Inhibitor Drugs that are strong inhibitors of CYP3A4 (e.g., ketoconazole and itraconazole) decrease gefitinib metabolism and increase gefitinib plasma concentrations.
Monitor adverse reactions when administering strong CYP3A4 inhibitors with IRESSA.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.