Etravirine and Nilotinib interaction

Etravirine and Nilotinib: the Nilotinib prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Nilotinib (CAVHANZA) label · effective 2026-08-07

Major

Strong CYP3A Inducers: Avoid concomitant use with CAVHANZA.

Drug interactionsby drug classView label on DailyMed
Major

Strong CYP3A Inducers Avoid concomitant use of strong CYP3A inducers with CAVHANZA.

Drug interactionsby drug classView label on DailyMed
Moderate

Concomitant use with a strong CYP3A inducer decreases nilotinib exposure [see Clinical Pharmacology ( 12.3 )] which may reduce CAVHANZA efficacy.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.