Fluvoxamine and Ketorolac interaction
Fluvoxamine and Ketorolac: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Fluvoxamine (fluvoxamine maleate) label · effective 2026-04-23
Other Drugs Affecting Hemostasis: Increased risk of bleeding with concomitant use of NSAIDs, aspirin, or other drugs affecting coagulation ( 5.8 , 5.10 ).
These studies have also shown that concurrent use of an NSAID or aspirin may potentiate this risk of bleeding.
Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, warfarin, and other anticoagulants may add to this risk.
Patients should be cautioned about the increased risk of bleeding associated with the concomitant use of Fluvoxamine Maleate Tablets and NSAIDs, aspirin, or other drugs that affect coagulation [see Warnings and Precautions ( 5.8 )] .
Warfarin and Other Drugs That Interfere With Hemostasis (NSAIDs, Aspirin, etc.): See Warnings and Precautions ( 5.8 , 5.10 ) .
From the Ketorolac (Ketorolac Tromethamine) label · effective 2024-12-31
Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs.
Caution should be used when NSAIDs are administered concomitantly with SSRIs.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.