Gemfibrozil and Probenecid and colchicine interaction
Gemfibrozil and Probenecid and colchicine: the Gemfibrozil prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Gemfibrozil (Lopid) label · effective 2026-05-21
(G) Colchicine Myopathy, including rhabdomyolysis, has been reported with chronic administration of colchicine at therapeutic doses.
Caution should be exercised when prescribing LOPID with colchicine, especially in elderly patients or patients with renal dysfunction.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.