Glycerol phenylbutyrate and Sodium phenylacetate and sodium benzoate interaction

Glycerol phenylbutyrate and Sodium phenylacetate and sodium benzoate: the Glycerol phenylbutyrate prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Glycerol phenylbutyrate label · effective 2025-06-30

Moderate

In a study of adult cancer patients, subjects received sodium phenylacetate administered as a 1-hour infusion twice daily at two dose levels of 125 and 150 mg/kg for a 2-week period.

Warnings and precautionsnames Sodium phenylacetate and sodium benzoateView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.