Hydrochlorothiazide and Zinc interaction

Hydrochlorothiazide and Zinc: NIH and FDA consumer guidance mention this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

Curated guidance for Zinc

Minor

Thiazide diuretics increase zinc loss in urine with long-term use.

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.