Indomethacin and Latanoprost interaction
Indomethacin and Latanoprost: the Indomethacin prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Indomethacin (Indocin) label · effective 2024-12-16
Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion.
In these patients, administration of an NSAID may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation.
This effect has been attributed to NSAID inhibition of renal prostaglandin synthesis Intervention: During concomitant use of INDOCIN and lithium, monitor patients for signs of lithium toxicity.
This effect has been attributed to the NSAID inhibition of renal prostaglandin synthesis.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.