Lansoprazole and Theophylline interaction

Lansoprazole and Theophylline: the Lansoprazole prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Lansoprazole (Prevacid) label · effective 2025-07-08

Moderate

Theophylline Clinical Impact: Increased clearance of theophylline [see Clinical Pharmacology (12.3) ] .

Drug interactionsnames TheophyllineView label on DailyMed
Moderate

Intervention: Individual patients may require additional titration of their theophylline dosage when PREVACID or PREVACID SoluTab is started or stopped to ensure clinically effective blood concentrations.

Drug interactionsnames TheophyllineView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.