Ledipasvir and sofosbuvir and St. John's wort interaction
Ledipasvir and sofosbuvir and St. John's wort: the Ledipasvir and sofosbuvir prescribing label mentions this combination without an instruction to avoid it or change the dose.
Minor
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Ledipasvir and sofosbuvir label · effective 2025-01-10
Minor
John's wort (Hypericum perforatum) ↓ ledipasvir ↓ sofosbuvir Coadministration of ledipasvir and sofosbuvir with St.
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Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.