Megestrol and Rifabutin interaction

Megestrol and Rifabutin: the Megestrol prescribing label reports no clinically significant interaction between these two.

No interaction

No clinically significant interaction reported. The label studied or considered this pair and found nothing meaningful.

What the FDA labels say

From the Megestrol (Megestrol Acetate) label · effective 2026-04-14

No interaction

Zidovudine and Rifabutin No dosage adjustment for zidovudine and rifabutin is needed when megestrol acetate is coadministered with these drugs [See Clinical Pharmacology ( 12.3 )] .

Drug interactionsnames RifabutinView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.