Methamphetamine and Protamine interaction
Methamphetamine and Protamine: the Protamine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.
Major
Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.
What the FDA labels say
From the Protamine (Protamine Sulfate) label · effective 2025-04-29
Major
Vasopressors and resuscitation equipment should be immediately available in case of a severe reaction to protamine.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.