Nortriptyline and Propranolol interaction
Nortriptyline and Propranolol: both prescribing labels mention this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Nortriptyline (PAMELOR) label · effective 2024-12-04
The antihypertensive action of guanethidine and similar agents may be blocked.
From the Propranolol (InnoPran XL) label · effective 2026-08-27
Antidepressants: The hypotensive effect of MAO inhibitors or tricyclic antidepressants may be exacerbated when administered with beta-blockers.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.