Sitagliptin and Temsirolimus interaction

Sitagliptin and Temsirolimus: the Temsirolimus prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Temsirolimus (Torisel) label · effective 2025-12-26

Moderate

This may result in the need for an increase in the dose of, or initiation of, insulin and/or oral hypoglycemic agent therapy.

Warnings and precautionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.