Furosemid: interakcje

Avoid concomitant use of ARIKAYCE with ethacrynic acid, furosemide, urea, or intravenous mannitol. (etykieta leku Amikacyna, Interakcje z innymi lekami)

Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (etykieta leku Amiloryd, Ostrzeżenie w ramce)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etykieta leku Chinapryl, Ostrzeżenia)

…sometimes associated with oliguria and/or progressive azotemia, and rarely acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis or severe volume and/or salt depletion of any etiology. (etykieta leku Chinapryl + hydrochlorotiazyd, Ostrzeżenia)

Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etykieta leku Choriogonadotropina alfa, Ostrzeżenia)

Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etykieta leku Cyklosporyna, Interakcje z innymi lekami)

The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (etykieta leku Cytrynian potasu, Interakcje z innymi lekami)

In the DIAMOND trials, 1252 patients were treated with dofetilide and diuretics concomitantly, of whom 493 died compared to 508 deaths among the 1248 patients receiving placebo and diuretics. (etykieta leku Dofetylid, Interakcje z innymi lekami)

Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etykieta leku Droperydol, Ostrzeżenie w ramce)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etykieta leku Enalaprylat, Ostrzeżenia)

…• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (etykieta leku Eplerenon, Przeciwwskazania)

…of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etykieta leku Eptyfibatyd, Przeciwwskazania)

Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etykieta leku Folitropina, Ostrzeżenia i środki ostrożności)

The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etykieta leku Gentamycyna, Ostrzeżenie w ramce)

Avoid diuretics or laxatives in patients with diarrhea. (etykieta leku Irynotekan, Ostrzeżenia i środki ostrożności)

Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etykieta leku Itrakonazol, Interakcje z innymi lekami)

Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etykieta leku Klozapina, Ostrzeżenie w ramce)

Avoid concomitant use with ethacrynic acid. (etykieta leku Furosemid, Interakcje z innymi lekami)

Avoid concomitant use with lithium. (etykieta leku Furosemid, Interakcje z innymi lekami)

Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etykieta leku Metolazon, Ostrzeżenia)

Therefore, furosemide should not be administered in intravenous lines containing milrinone. (etykieta leku Milrinon, Interakcje z innymi lekami)

Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (etykieta leku Minoksydyl, Ostrzeżenie w ramce)

The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etykieta leku Neomycyna, Ostrzeżenie w ramce)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etykieta leku Spironolakton + hydrochlorotiazyd, Przeciwwskazania)

…coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etykieta leku Tadalafil, Ostrzeżenia i środki ostrożności)

TOBI Podhaler should not be administered concomitantly with ethacrynic acid, furosemide, urea, or intravenous mannitol. (etykieta leku Tobramycyna, Interakcje z innymi lekami)

Hyperkalemia Abnormal elevation of serum potassium levels (≥5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including triamterene and hydrochlorothiazide. (etykieta leku Triamteren + hydrochlorotiazyd, Ostrzeżenie w ramce)

The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etykieta leku Trójtlenek arsenu, Ostrzeżenia i środki ostrożności)

Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etykieta leku Wodorowęglan sodu, Przeciwwskazania)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

…Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (etykieta leku Adrenalina, Interakcje z innymi lekami)

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etykieta leku Alfuzosyna, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etykieta leku Allopurynol, Ostrzeżenia i środki ostrożności)

Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs and isoniazid Alogliptin Cytochrome (CYP) P450, CYP-Substrates or Inhibitors Clinical Impact: Insulin Secretagogues and Insulin Insulin and insulin secretagogues… (etykieta leku Alogliptyna + metformina, Interakcje z innymi lekami)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (etykieta leku Amfepramon (dietylopropion), Interakcje z innymi lekami)

Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (etykieta leku Amiodaron, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etykieta leku Arformoterol, Interakcje z innymi lekami)

There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (etykieta leku Armodafinil, Ostrzeżenia i środki ostrożności)

Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etykieta leku Arypiprazol, Interakcje z innymi lekami)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etykieta leku Asenapina, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etykieta leku Atomoksetyna, Interakcje z innymi lekami)

• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etykieta leku Awanafil, Ostrzeżenia i środki ostrożności)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Amphetamines may decrease the hypotensive effect of antihypertensives. (etykieta leku Benzfetamina, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ) [see Use in Specific Populations ( 8.6 )] , elderly patients, patients with low systolic blood pressure, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etykieta leku Bexagliflozin, Ostrzeżenia i środki ostrożności)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etykieta leku Bortezomib, Ostrzeżenia i środki ostrożności)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etykieta leku Brekspiprazol, Ostrzeżenia i środki ostrożności)

Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etykieta leku Bromfeniramina + pseudoefedryna + dekstrometorfan, Interakcje z innymi lekami)

Use caution in patients taking antihypertensive medications. (etykieta leku Bromokryptyna, Ostrzeżenia i środki ostrożności)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etykieta leku Brymonidyna, Interakcje z innymi lekami)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etykieta leku Brymonidyna + tymolol, Interakcje z innymi lekami)

Diuretics: Use with caution. (etykieta leku Budezonid + formoterol, Interakcje z innymi lekami)

In these test animals bumetanide was 5 to 6 times more potent than furosemide and, since the diuretic potency of bumetanide is about 40 to 60 times furosemide, it is anticipated that blood levels necessary to produce ototoxicity will rarely be achieved. (etykieta leku Bumetanid, Ostrzeżenia)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Buprenorfina, Interakcje z innymi lekami)

Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Buprenorfina + nalokson, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Butalbital + paracetamol + kofeina + kodeina, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etykieta leku Furosemid, Interakcje z innymi lekami)

• Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Celekoksyb, Interakcje z innymi lekami)

Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (etykieta leku Chinidyna, Interakcje z innymi lekami)

Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etykieta leku Chlorek wapnia, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etykieta leku Chlorpromazyna, Środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

• Cisplatin and nephrotoxic drugs : Risk of ototoxicity and nephrotoxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

…concomitant use of TONMYA with: MAO inhibitors may be life-threatening [see Contraindications (4) ] , Alcohol, barbiturates, and other CNS depressants may increase the risk of adverse reactions associated with these drugs, Tramadol may increase the seizure risk, Guanethidine or other similar acting drugs may block the antihypertensive action of these drugs. (etykieta leku Cyklobenzapryna, Interakcje z innymi lekami)

…inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity ● Amiodarone… (etykieta leku Cyklofosfamid, Interakcje z innymi lekami)

However, there was an increase in systemic exposure to weak acids such as furosemide and atorvastatin, and a decrease in systemic exposure to weak bases such as dabigatran when co-administered with LOKELMA, as shown in Figure 2. (etykieta leku Cyklokrzemian sodowo-cyrkonowy, Interakcje z innymi lekami)

Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etykieta leku Cytalopram, Ostrzeżenia i środki ostrożności)

Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etykieta leku Dapagliflozyna, Ostrzeżenia i środki ostrożności)

Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etykieta leku Dapagliflozyna + metformina, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etykieta leku Dekslanzoprazol, Ostrzeżenia i środki ostrożności)

• Antihypertensive Drugs: Monitor blood pressure. (etykieta leku Deksmetylofenidat, Interakcje z innymi lekami)

…Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etykieta leku Desmopresyna, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etykieta leku Deswenlafaksyna, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etykieta leku Dezypramina, Ostrzeżenia)

The concomitant administration of thiazides or other diuretics may potentiate the hyperglycemic and hyperuricemic effects of PROGLYCEM. (etykieta leku Diazoksyd, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (etykieta leku Digoksyna, Ostrzeżenia i środki ostrożności)

Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Diklofenak, Interakcje z innymi lekami)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Drugs that Cause Hypokalemia The risk of hypokalemia is greater with coadministration of KEVEYIS and other drugs that can cause hypokalemia (e.g., loop diuretics, thiazide diuretics, laxatives, antifungals, penicillins, and theophylline) [see Warnings and Precautions (5.3) ] . (etykieta leku Diklofenamid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etykieta leku Dokserkalcyferol, Ostrzeżenia i środki ostrożności)

Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (etykieta leku Drospirenon + etynyloestradiol, Ostrzeżenia i środki ostrożności)

The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (etykieta leku Duloksetyna, Ostrzeżenia i środki ostrożności)

While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the dose of tamsulosin [see Clinical Pharmacology (12.3) ] . (etykieta leku Dutasteryd + tamsulosyna, Interakcje z innymi lekami)

Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etykieta leku Empagliflozyna, Ostrzeżenia i środki ostrożności)

Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etykieta leku Empagliflozyna + metformina, Ostrzeżenia i środki ostrożności)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etykieta leku Epoetyna alfa, Ostrzeżenia i środki ostrożności)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etykieta leku Escytalopram, Ostrzeżenia i środki ostrożności)

Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etykieta leku Esmolol, Interakcje z innymi lekami)

Nevertheless, clinical studies, as well as postmarketing observations have shown that etodolac can reduce the natriuretic effect of furosemide and thiazides in some patients with possible loss of blood pressure control. (etykieta leku Etodolak, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etykieta leku Ezomeprazol, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

…hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (etykieta leku Fenelzyna, Ostrzeżenia)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Fenoprofen, Interakcje z innymi lekami)

…treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (etykieta leku Fentanyl, Ostrzeżenia i środki ostrożności)

In addition, when phentermine and topiramate extended-release capsules are used in conjunction with nonpotassium sparing diuretics this may further potentiate potassium-wasting. (etykieta leku Fentermina + topiramat, Ostrzeżenia i środki ostrożności)

Warfarin Increased and decreased PT/INR responses have been reported when phenytoin is coadministered with warfarin Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Anticoagulants Apixaban, dabigatran, edoxaban, rivaroxaban… (etykieta leku Fenytoina, Interakcje z innymi lekami)

Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (etykieta leku Fludrokortyzon, Interakcje z innymi lekami)

An effect of this magnitude should not necessitate a change in the fluconazole dose regimen in subjects receiving concomitant diuretics. (etykieta leku Flukonazol, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etykieta leku Fluoksetyna, Ostrzeżenia i środki ostrożności)

Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Flurbiprofen, Interakcje z innymi lekami)

Diuretics: Use with caution. (etykieta leku Flutykazon + salmeterol, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etykieta leku Fluwoksamina, Ostrzeżenia i środki ostrożności)

• Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etykieta leku Formoterol, Interakcje z innymi lekami)

Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Anticoagulants Apixaban, dabigatran, edoxaban, rivaroxaban Antiepileptic drugs The effect of phenytoin on phenobarbital, valproic acid and sodium valproate serum levels… (etykieta leku Fosfenytoina, Interakcje z innymi lekami)

When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etykieta leku Foskarnet, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

…danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline),… (etykieta leku Glimepiryd, Interakcje z innymi lekami)

…may reduce the glucose-lowering effect of GLUCOTROL XL, leading to worsening glycemic control: atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic… (etykieta leku Glipizyd, Interakcje z innymi lekami)

Metformin Hydrochloride: Furosemide: A single-dose, metformin-furosemide drug interaction study in healthy subjects demonstrated that pharmacokinetic parameters of both compounds were affected by co-administration. (etykieta leku Glipizyd + metformina, Środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etykieta leku Haloperydol, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Hydrokodon, Interakcje z innymi lekami)

Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etykieta leku Hydrokodon + chlorfenamina, Interakcje z innymi lekami)

Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etykieta leku Hydrokodon + homatropina, Interakcje z innymi lekami)

Patients taking angiotensin converting enzyme (ACE) inhibitors, thiazide diuretics, or loop diuretics may have impaired response to these therapies when taking NSAIDs (see PRECAUTIONS: Drug Interactions). (etykieta leku Hydrokodon + ibuprofen, Ostrzeżenia)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Hydrokodon + paracetamol, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Hydromorfon, Interakcje z innymi lekami)

Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Ibuprofen, Interakcje z innymi lekami)

Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly. (etykieta leku Ibuprofen + famotydyna, Ostrzeżenia i środki ostrożności)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etykieta leku Iloperydon, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etykieta leku Imipramina, Ostrzeżenia)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Aspart Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g.,… (etykieta leku Insulina aspart, Interakcje z innymi lekami)

Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Degludec Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g.,… (etykieta leku Insulina degludec, Interakcje z innymi lekami)

Drugs That May Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol,… (etykieta leku Insulina detemir, Interakcje z innymi lekami)

Drugs that May Decrease the Blood Glucose Lowering Effect of Insulin Glargine-yfgn Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents… (etykieta leku Insulina glargine, Interakcje z innymi lekami)

Drugs That May Decrease the Blood Glucose Lowering Effect of LYUMJEV Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol,… (etykieta leku Insulina lispro, Interakcje z innymi lekami)

Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (etykieta leku Ipratropium + salbutamol, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etykieta leku Jodek potasu, Interakcje z innymi lekami)

Monitor patients for increased toxicity when MRP2 inhibitors (e.g., abacavir, adefovir, cidofovir, furosemide, lamivudine, nevirapine, ritonavir, probenecid, saquinavir, and tenofovir) are co-administered with COMETRIQ [see Clinical Pharmacology ( 12.3 )] . (etykieta leku Kabozantynib, Interakcje z innymi lekami)

Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etykieta leku Kanagliflozyna, Ostrzeżenia i środki ostrożności)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etykieta leku Karbamazepina, Ostrzeżenia i środki ostrożności)

Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etykieta leku Karbidopa, Interakcje z innymi lekami)

Antihypertensive drugs: May cause symptomatic postural hypotension. (etykieta leku Karbidopa + lewodopa, Interakcje z innymi lekami)

Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etykieta leku Karbidopa + lewodopa + entakapon, Interakcje z innymi lekami)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etykieta leku Kariprazyna, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (etykieta leku Ketokonazol, Interakcje z innymi lekami)

Diuretics NSAIDs can reduce the natriuretic effect of furosemide and thiazides in some patients. (etykieta leku Ketoprofen, Ostrzeżenia i środki ostrożności)

Diuretics Clinical studies, as well as postmarketing observations, have shown that ketorolac tromethamine can reduce the natriuretic effect of furosemide and thiazides in some patients. (etykieta leku Ketorolak, Interakcje z innymi lekami)

Consider use of diuretics and/or albumin. (etykieta leku Klofarabina, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Kodeina, Interakcje z innymi lekami)

The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (etykieta leku Kolestypol, Interakcje z innymi lekami)

Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etykieta leku Kolestyramina, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (etykieta leku Kwas mefenamowy, Ostrzeżenia i środki ostrożności)

Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etykieta leku Kwas zoledronowy, Ostrzeżenia i środki ostrożności)

Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etykieta leku Kwetiapina, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etykieta leku Lanzoprazol, Ostrzeżenia i środki ostrożności)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

In patients taking ARAVA, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased. (etykieta leku Leflunomid, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etykieta leku Lewomilnacypran, Ostrzeżenia i środki ostrożności)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Leworfanol, Interakcje z innymi lekami)

Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etykieta leku Lewosalbutamol, Interakcje z innymi lekami)

Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etykieta leku Furosemid, Interakcje z innymi lekami)

Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (etykieta leku Linezolid, Ostrzeżenia i środki ostrożności)

Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etykieta leku Lumateperon, Ostrzeżenia i środki ostrożności)

Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etykieta leku Lurazydon, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

However, studies with furosemide agents and meloxicam have not demonstrated a reduction in natriuretic effect. (etykieta leku Meloksykam, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (etykieta leku Metadon, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Methotrexate and other drugs undergoing renal tubular secretion Furosemide may decrease renal elimination of other drugs that undergo tubular secretion. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Antihypertensive Drugs: Monitor blood pressure. (etykieta leku Metylofenidat, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etykieta leku Milnacypran, Ostrzeżenia i środki ostrożności)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etykieta leku Mirtazapina, Ostrzeżenia i środki ostrożności)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (etykieta leku Modafinil, Ostrzeżenia i środki ostrożności)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Morfina, Interakcje z innymi lekami)

Diuretics: Clinical studies, as well as post marketing observations, have shown that nabumetone can reduce the natriuretic effect of furosemide and thiazides in some patients. (etykieta leku Nabumeton, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Nalbufina, Interakcje z innymi lekami)

Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Naproksen, Interakcje z innymi lekami)

Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly. (etykieta leku Naproksen + ezomeprazol, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etykieta leku Niacyna (kwas nikotynowy), Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (etykieta leku Nimodypina, Interakcje z innymi lekami)

Antihypertensives: Possible additive hypotensive effects. (etykieta leku Nitrogliceryna, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Oksaprozyna, Interakcje z innymi lekami)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Oksykodon, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Oksykodon + paracetamol, Interakcje z innymi lekami)

Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Oksymorfon, Interakcje z innymi lekami)

…of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etykieta leku Olanzapina, Ostrzeżenia i środki ostrożności)

…and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etykieta leku Olanzapina + fluoksetyna, Ostrzeżenia i środki ostrożności)

Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Olicerydyna, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etykieta leku Omeprazol, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etykieta leku Omeprazol + wodorowęglan sodu, Ostrzeżenia i środki ostrożności)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etykieta leku Paliperydon, Ostrzeżenia i środki ostrożności)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etykieta leku Pantoprazol, Ostrzeżenia i środki ostrożności)

• Hypertension : Patients taking some antihypertensive medications may have impaired response to these therapies when taking NSAIDs. (etykieta leku Paracetamol + ibuprofen, Ostrzeżenia i środki ostrożności)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Paracetamol + kodeina, Interakcje z innymi lekami)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (etykieta leku Paroksetyna, Ostrzeżenia i środki ostrożności)

The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etykieta leku Parykalcytol, Ostrzeżenia i środki ostrożności)

Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etykieta leku Pazopanib, Ostrzeżenia i środki ostrożności)

Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Pentazocyna + nalokson, Interakcje z innymi lekami)

Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etykieta leku Pentoksyfilina, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Petydyna, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

…danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline),… (etykieta leku Pioglitazon + glimepiryd, Interakcje z innymi lekami)

Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etykieta leku Piroksykam, Interakcje z innymi lekami)

Reports usually indicate that furosemide ototoxicity is associated with rapid injection, severe renal impairment, the use of higher than recommended doses, hypoproteinemia or concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs. (etykieta leku Furosemid, Ostrzeżenia i środki ostrożności)

Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Pokrzyk wilcza jagoda (belladonna) + opium, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etykieta leku Prochlorperazyna, Środki ostrożności)

Diuretics : Codeine may reduce the efficacy of diuretics. (etykieta leku Prometazyna + kodeina, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etykieta leku Furosemid, Interakcje z innymi lekami)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etykieta leku Rabeprazol, Ostrzeżenia i środki ostrożności)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etykieta leku Riocyguat, Ostrzeżenia i środki ostrożności)

Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etykieta leku Rysperydon, Ostrzeżenia i środki ostrożności)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics: Use with caution. (etykieta leku Salbutamol, Interakcje z innymi lekami)

• Diuretics: Use with caution. (etykieta leku Salmeterol, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etykieta leku Sertralina, Ostrzeżenia i środki ostrożności)

Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etykieta leku Sorafenib, Ostrzeżenia i środki ostrożności)

Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etykieta leku Sotalol, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Paralytic agents Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine. (etykieta leku Furosemid, Interakcje z innymi lekami)

Drug Interactions In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. (etykieta leku Sulfametoksazol + trimetoprim, Interakcje z innymi lekami)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics Clinical studies, as well as post marketing observations, have shown that sulindac can reduce the natriuretic effect of furosemide and thiazides in some patients. (etykieta leku Sulindak, Interakcje z innymi lekami)

Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, salt depletion, those taking diuretics and angiotensin-converting enzyme (ACE) inhibitors or ARBs, and the elderly. (etykieta leku Sumatryptan + naproksen, Ostrzeżenia i środki ostrożności)

Initiate and/or adjust antihypertensive therapy as appropriate. (etykieta leku Sunitynib, Ostrzeżenia i środki ostrożności)

Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etykieta leku Syldenafil, Ostrzeżenia i środki ostrożności)

However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etykieta leku Sylodosyna, Ostrzeżenia i środki ostrożności)

• Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etykieta leku Takrolimus, Ostrzeżenia i środki ostrożności)

While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the tamsulosin hydrochloride capsules dosage [see Clinical Pharmacology ( 12.3 )] . (etykieta leku Tamsulosyna, Interakcje z innymi lekami)

…use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Tapentadol, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etykieta leku Terbutalina, Środki ostrożności)

In patients taking AUBAGIO, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased. (etykieta leku Teryflunomid, Interakcje z innymi lekami)

Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etykieta leku Furosemid, Interakcje z innymi lekami)

In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (etykieta leku Testosteron, Ostrzeżenia i środki ostrożności)

Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etykieta leku Furosemid, Interakcje z innymi lekami)

Diuretics: Clinical studies, as well as post-marketing observations have shown that NSAIDs can reduce the natriuretic effect of furosemide and thiazides in some patients. (etykieta leku Tolmetyna, Interakcje z innymi lekami)

Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etykieta leku Tolwaptan, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etykieta leku Toremifen, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Tramadol, Interakcje z innymi lekami)

Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etykieta leku Tramadol + paracetamol, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etykieta leku Trazodon, Ostrzeżenia i środki ostrożności)

Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etykieta leku Furosemid, Interakcje z innymi lekami)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etykieta leku Trifluoperazyna, Środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

• Diuretics: Use with caution. (etykieta leku Umeklidynium + wilanterol, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etykieta leku Furosemid, Interakcje z innymi lekami)

Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etykieta leku Wardenafil, Interakcje z innymi lekami)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etykieta leku Wenlafaksyna, Ostrzeżenia i środki ostrożności)

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etykieta leku Furosemid, Interakcje z innymi lekami)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etykieta leku Wilazodon, Ostrzeżenia i środki ostrożności)

Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etykieta leku Wortioksetyna, Ostrzeżenia i środki ostrożności)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etykieta leku Furosemid, Interakcje z innymi lekami)

Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etykieta leku Zyprazydon, Ostrzeżenia i środki ostrożności)

These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel-blocking drugs, and isoniazid. (etykieta leku Akarboza, Interakcje z innymi lekami)

Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etykieta leku Ambrisentan, Ostrzeżenia i środki ostrożności)

These drugs include: aspirin, phenylbutazone, sulfonamides, indomethacin, thiazide diuretics, furosemide and ethacrynic acid. (etykieta leku Benzylopenicylina, Interakcje z innymi lekami)

Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etykieta leku Bosentan, Ostrzeżenia i środki ostrożności)

In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs. (etykieta leku Butorfanol, Ostrzeżenia)

…Probenecid Probenecid is known to interact with the metabolism or renal tubular excretion of many drugs (e.g., acetaminophen, acyclovir, angiotensin-converting enzyme inhibitors, aminosalicylic acid, barbiturates, benzodiazepines, bumetanide, clofibrate, methotrexate, famotidine, furosemide, nonsteroidal anti-inflammatory agents, theophylline, and zidovudine). (etykieta leku Cydofowir, Interakcje z innymi lekami)

Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etykieta leku Dazatynib, Ostrzeżenia i środki ostrożności)

Antihypertensives Amphetamines may antagonize the hypotensive effects of antihypertensives. (etykieta leku Deksamfetamina, Interakcje z innymi lekami)

If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etykieta leku Dezogestrel + etynyloestradiol, Ostrzeżenia)

Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (etykieta leku Dobutamina, Interakcje z innymi lekami)

Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etykieta leku Docetaksel, Ostrzeżenia i środki ostrożności)

Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (etykieta leku Dronedaron, Ostrzeżenia i środki ostrożności)

Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (etykieta leku Efedryna, Interakcje z innymi lekami)

In addition to discontinuation of the drug, diuretic therapy may be required. (etykieta leku Estrogeny estryfikowane + metylotestosteron, Ostrzeżenia)

…clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (etykieta leku Finasteryd, Interakcje z innymi lekami)

Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (etykieta leku Flekainid, Interakcje z innymi lekami)

These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (etykieta leku Glibenklamid, Interakcje z innymi lekami)

Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etykieta leku Glibenklamid + metformina, Interakcje z innymi lekami)

Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (etykieta leku Glukonian wapnia, Interakcje z innymi lekami)

• Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (etykieta leku Hialuronidaza, Interakcje z innymi lekami)

ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etykieta leku Ikatybant, Interakcje z innymi lekami)

Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (etykieta leku Imatynib, Ostrzeżenia i środki ostrożności)

Atypical Antipsychotics (e.g., olanzapine and clozapine), Corticosteroids, Danazol, Diuretics, Estrogens, Glucagon, Isoniazid, Niacin, Oral Contraceptives, Phenothiazines, Progestogens (e.g., in oral contraceptives), Protease inhibitors, Somatropin, Sympathomimetic Agents (e.g., albuterol, epinephrine, terbutaline) and Thyroid Hormones. (etykieta leku Insulina ludzka krótko działająca, Interakcje z innymi lekami)

Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etykieta leku Kortykotropina, Interakcje z innymi lekami)

These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (etykieta leku Linagliptyna + metformina, Interakcje z innymi lekami)

Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etykieta leku Macytentan, Ostrzeżenia i środki ostrożności)

Długotrwałe stosowanie diuretyków pętlowych i tiazydowych zwiększa utratę magnezu z moczem. (NIH Office of Dietary Supplements, Magnesium)

In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etykieta leku Meksyletyna, Interakcje z innymi lekami)

Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etykieta leku Metformina, Interakcje z innymi lekami)

Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

In addition to discontinuation of the drug, diuretic therapy may be required. (etykieta leku Metylotestosteron, Ostrzeżenia)

The antihypertensive action of guanethidine and similar agents may be blocked. (etykieta leku Nortryptylina, Ostrzeżenia)

These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etykieta leku Pioglitazon + metformina, Interakcje z innymi lekami)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (etykieta leku Piperacylina + tazobaktam, Ostrzeżenia i środki ostrożności)

Diuretyki pętlowe i tiazydowe zwiększają utratę potasu; niekiedy razem z nimi przepisuje się suplementację. (NIH Office of Dietary Supplements, Potassium)

Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizolon, Interakcje z innymi lekami)

Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etykieta leku Prednizon, Interakcje z innymi lekami)

Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etykieta leku Protryptylina, Ostrzeżenia)

Examples: Atypical antipsychotics (e.g., olanzapine and clozapine), calcium channel antagonists, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and… (etykieta leku Repaglinid, Interakcje z innymi lekami)

These medications include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (etykieta leku Saksagliptyna + metformina, Interakcje z innymi lekami)

Potentiation of the action of sulfonylurea hypoglycemic agents, thiazide diuretics and uricosuric agents may also be noted. (etykieta leku Sulfadiazyna, Interakcje z innymi lekami)

Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etykieta leku Sytagliptyna + metformina, Interakcje z innymi lekami)

There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (etykieta leku Terbinafina, Interakcje z innymi lekami)

Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Triamcynolon, Interakcje z innymi lekami)

Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etykieta leku Kwas pamidronowy, Interakcje z innymi lekami)