Interacciones de Furosemida
Furosemida (Lasix, Furoscix), diurético de asa, tiene 384 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 29; moderadas: 310; leves: 44; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 1. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.
Interacciones según la etiqueta
Interacciones graves (29)
Avoid concomitant use with ethacrynic acid. (etiqueta de Furosemida, Interacciones medicamentosas)
Avoid concomitant use of ARIKAYCE with ethacrynic acid, furosemide, urea, or intravenous mannitol. (etiqueta de Amikacina, Interacciones medicamentosas)
Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (etiqueta de Amilorida, Advertencia en recuadro)
Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etiqueta de Bicarbonato de sodio, Contraindicaciones)
Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etiqueta de Ciclosporina, Interacciones medicamentosas)
The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (etiqueta de Citrato de potasio, Interacciones medicamentosas)
Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etiqueta de Clozapina, Advertencia en recuadro)
Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etiqueta de Coriogonadotropina alfa, Advertencias)
In the DIAMOND trials, 1252 patients were treated with dofetilide and diuretics concomitantly, of whom 493 died compared to 508 deaths among the 1248 patients receiving placebo and diuretics. (etiqueta de Dofetilida, Interacciones medicamentosas)
Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etiqueta de Droperidol, Advertencia en recuadro)
…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Enalaprilato, Advertencias)
…• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (etiqueta de Eplerenona, Contraindicaciones)
…of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etiqueta de Eptifibatida, Contraindicaciones)
CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)
- FolitropinaGrave
Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etiqueta de Folitropina, Advertencias y precauciones)
The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Gentamicina, Advertencia en recuadro)
- IrinotecánGrave
Avoid diuretics or laxatives in patients with diarrhea. (etiqueta de Irinotecán, Advertencias y precauciones)
Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etiqueta de Itraconazol, Interacciones medicamentosas)
Avoid concomitant use with lithium. (etiqueta de Furosemida, Interacciones medicamentosas)
Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)
Therefore, furosemide should not be administered in intravenous lines containing milrinone. (etiqueta de Milrinona, Interacciones medicamentosas)
Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (etiqueta de Minoxidil, Advertencia en recuadro)
The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Neomicina, Advertencia en recuadro)
…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Quinapril, Advertencias)
…sometimes associated with oliguria and/or progressive azotemia, and rarely acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis or severe volume and/or salt depletion of any etiology. (etiqueta de Quinapril e hidroclorotiazida, Advertencias)
…coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etiqueta de Tadalafilo, Advertencias y precauciones)
TOBI Podhaler should not be administered concomitantly with ethacrynic acid, furosemide, urea, or intravenous mannitol. (etiqueta de Tobramicina, Interacciones medicamentosas)
Hyperkalemia Abnormal elevation of serum potassium levels (≥5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including triamterene and hydrochlorothiazide. (etiqueta de Triamtereno e hidroclorotiazida, Advertencia en recuadro)
The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etiqueta de Trióxido de arsénico, Advertencias y precauciones)
Interacciones moderadas (310)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors or ARBs, and the elderly. (etiqueta de Ácido mefenámico, Advertencias y precauciones)
Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etiqueta de Ácido zoledrónico, Advertencias y precauciones)
…Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (etiqueta de Adrenalina, Interacciones medicamentosas)
Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etiqueta de Alfuzosina, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs and isoniazid Alogliptin Cytochrome (CYP) P450, CYP-Substrates or Inhibitors Clinical Impact: Insulin Secretagogues and Insulin Insulin and insulin secretagogues… (etiqueta de Alogliptina y metformina, Interacciones medicamentosas)
Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etiqueta de Alopurinol, Advertencias y precauciones)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (etiqueta de Amiodarona, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (etiqueta de Anfepramona, Interacciones medicamentosas)
Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etiqueta de Arformoterol, Interacciones medicamentosas)
Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etiqueta de Aripiprazol, Interacciones medicamentosas)
There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (etiqueta de Armodafinilo, Advertencias y precauciones)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Asenapina, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etiqueta de Atomoxetina, Interacciones medicamentosas)
• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etiqueta de Avanafilo, Advertencias y precauciones)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Belladona y opio, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Amphetamines may decrease the hypotensive effect of antihypertensives. (etiqueta de Benzfetamina, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ) [see Use in Specific Populations ( 8.6 )] , elderly patients, patients with low systolic blood pressure, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etiqueta de Bexagliflozina, Advertencias y precauciones)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
- BortezomibModerada
Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Brexpiprazol, Advertencias y precauciones)
Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etiqueta de Brimonidina, Interacciones medicamentosas)
Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etiqueta de Brimonidina y timolol, Interacciones medicamentosas)
Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etiqueta de Bromfeniramina, pseudoefedrina y dextrometorfano, Interacciones medicamentosas)
Use caution in patients taking antihypertensive medications. (etiqueta de Bromocriptina, Advertencias y precauciones)
Diuretics: Use with caution. (etiqueta de Budesonida y formoterol, Interacciones medicamentosas)
In these test animals bumetanide was 5 to 6 times more potent than furosemide and, since the diuretic potency of bumetanide is about 40 to 60 times furosemide, it is anticipated that blood levels necessary to produce ototoxicity will rarely be achieved. (etiqueta de Bumetanida, Advertencias)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Buprenorfina, Interacciones medicamentosas)
Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Buprenorfina y naloxona, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Butalbital, paracetamol, cafeína y codeína, Interacciones medicamentosas)
- CabozantinibModerada
Monitor patients for increased toxicity when MRP2 inhibitors (e.g., abacavir, adefovir, cidofovir, furosemide, lamivudine, nevirapine, ritonavir, probenecid, saquinavir, and tenofovir) are co-administered with COMETRIQ [see Clinical Pharmacology ( 12.3 )] . (etiqueta de Cabozantinib, Interacciones medicamentosas)
Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etiqueta de Canagliflozina, Advertencias y precauciones)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etiqueta de Carbamazepina, Advertencias y precauciones)
- CarbidopaModerada
Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etiqueta de Carbidopa, Interacciones medicamentosas)
Antihypertensive drugs: May cause symptomatic postural hypotension. (etiqueta de Carbidopa y levodopa, Interacciones medicamentosas)
Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etiqueta de Carbidopa, levodopa y entacapona, Interacciones medicamentosas)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Cariprazina, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (etiqueta de Furosemida, Interacciones medicamentosas)
• Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Celecoxib, Interacciones medicamentosas)
…concomitant use of TONMYA with: MAO inhibitors may be life-threatening [see Contraindications (4) ] , Alcohol, barbiturates, and other CNS depressants may increase the risk of adverse reactions associated with these drugs, Tramadol may increase the seizure risk, Guanethidine or other similar acting drugs may block the antihypertensive action of these drugs. (etiqueta de Ciclobenzaprina, Interacciones medicamentosas)
…inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity ● Amiodarone… (etiqueta de Ciclofosfamida, Interacciones medicamentosas)
However, there was an increase in systemic exposure to weak acids such as furosemide and atorvastatin, and a decrease in systemic exposure to weak bases such as dabigatran when co-administered with LOKELMA, as shown in Figure 2. (etiqueta de Ciclosilicato de sodio y zirconio, Interacciones medicamentosas)
- CisplatinoModerada
• Cisplatin and nephrotoxic drugs : Risk of ototoxicity and nephrotoxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Citalopram, Advertencias y precauciones)
Consider use of diuretics and/or albumin. (etiqueta de Clofarabina, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Clorpromazina, Precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
- Cloruro de calcioModerada
Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etiqueta de Cloruro de calcio, Interacciones medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Codeína, Interacciones medicamentosas)
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (etiqueta de Colestipol, Interacciones medicamentosas)
Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etiqueta de Colestiramina, Interacciones medicamentosas)
Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etiqueta de Dapagliflozina, Advertencias y precauciones)
Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etiqueta de Dapagliflozina y metformina, Advertencias y precauciones)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etiqueta de Desipramina, Advertencias)
- DesmopresinaModerada
…Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etiqueta de Desmopresina, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etiqueta de Desvenlafaxina, Advertencias y precauciones)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Dexlansoprazol, Advertencias y precauciones)
• Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Dexmetilfenidato, Interacciones medicamentosas)
- DiazóxidoModerada
The concomitant administration of thiazides or other diuretics may potentiate the hyperglycemic and hyperuricemic effects of PROGLYCEM. (etiqueta de Diazóxido, Interacciones medicamentosas)
Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Diclofenaco, Interacciones medicamentosas)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Drugs that Cause Hypokalemia The risk of hypokalemia is greater with coadministration of KEVEYIS and other drugs that can cause hypokalemia (e.g., loop diuretics, thiazide diuretics, laxatives, antifungals, penicillins, and theophylline) [see Warnings and Precautions (5.3) ] . (etiqueta de Diclorfenamida, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (etiqueta de Digoxina, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Doxercalciferol, Advertencias y precauciones)
Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (etiqueta de Drospirenona y etinilestradiol, Advertencias y precauciones)
The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (etiqueta de Duloxetina, Advertencias y precauciones)
While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the dose of tamsulosin [see Clinical Pharmacology (12.3) ] . (etiqueta de Dutasterida y tamsulosina, Interacciones medicamentosas)
Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etiqueta de Empagliflozina, Advertencias y precauciones)
Patients with impaired renal function (eGFR less than 60 mL/min/1.73 m 2 ), elderly patients, or patients on loop diuretics may be at increased risk for volume depletion or hypotension. (etiqueta de Empagliflozina y metformina, Advertencias y precauciones)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
- Epoetina alfaModerada
Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etiqueta de Epoetina alfa, Advertencias y precauciones)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Escitalopram, Advertencias y precauciones)
Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etiqueta de Esmolol, Interacciones medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Esomeprazol, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Nevertheless, clinical studies, as well as postmarketing observations have shown that etodolac can reduce the natriuretic effect of furosemide and thiazides in some patients with possible loss of blood pressure control. (etiqueta de Etodolaco, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
…hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (etiqueta de Fenelzina, Advertencias)
Warfarin Increased and decreased PT/INR responses have been reported when phenytoin is coadministered with warfarin Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Anticoagulants Apixaban, dabigatran, edoxaban, rivaroxaban… (etiqueta de Fenitoína, Interacciones medicamentosas)
Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Fenoprofeno, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
…treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (etiqueta de Fentanilo, Advertencias y precauciones)
In addition, when phentermine and topiramate extended-release capsules are used in conjunction with nonpotassium sparing diuretics this may further potentiate potassium-wasting. (etiqueta de Fentermina y topiramato, Advertencias y precauciones)
An effect of this magnitude should not necessitate a change in the fluconazole dose regimen in subjects receiving concomitant diuretics. (etiqueta de Fluconazol, Interacciones medicamentosas)
Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (etiqueta de Fludrocortisona, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Fluoxetina, Advertencias y precauciones)
Diuretics : NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Flurbiprofeno, Interacciones medicamentosas)
Diuretics: Use with caution. (etiqueta de Fluticasona y salmeterol, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Fluvoxamina, Advertencias y precauciones)
• Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etiqueta de Formoterol, Interacciones medicamentosas)
When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etiqueta de Foscarnet, Interacciones medicamentosas)
Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Anticoagulants Apixaban, dabigatran, edoxaban, rivaroxaban Antiepileptic drugs The effect of phenytoin on phenobarbital, valproic acid and sodium valproate serum levels… (etiqueta de Fosfenitoína, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
…danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline),… (etiqueta de Glimepirida, Interacciones medicamentosas)
…may reduce the glucose-lowering effect of GLUCOTROL XL, leading to worsening glycemic control: atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic… (etiqueta de Glipizida, Interacciones medicamentosas)
Metformin Hydrochloride: Furosemide: A single-dose, metformin-furosemide drug interaction study in healthy subjects demonstrated that pharmacokinetic parameters of both compounds were affected by co-administration. (etiqueta de Glipizida y metformina, Precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etiqueta de Haloperidol, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidrocodona, Interacciones medicamentosas)
Patients taking angiotensin converting enzyme (ACE) inhibitors, thiazide diuretics, or loop diuretics may have impaired response to these therapies when taking NSAIDs (see PRECAUTIONS: Drug Interactions). (etiqueta de Hidrocodona e ibuprofeno, Advertencias)
Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etiqueta de Hidrocodona y clorfenamina, Interacciones medicamentosas)
Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etiqueta de Hidrocodona y homatropina, Interacciones medicamentosas)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidrocodona y paracetamol, Interacciones medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidromorfona, Interacciones medicamentosas)
Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Ibuprofeno, Interacciones medicamentosas)
Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly. (etiqueta de Ibuprofeno y famotidina, Advertencias y precauciones)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Iloperidona, Advertencias y precauciones)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etiqueta de Imipramina, Advertencias)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Aspart Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g.,… (etiqueta de Insulina asparta, Interacciones medicamentosas)
Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Degludec Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g.,… (etiqueta de Insulina degludec, Interacciones medicamentosas)
Drugs That May Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol,… (etiqueta de Insulina detemir, Interacciones medicamentosas)
Drugs that May Decrease the Blood Glucose Lowering Effect of Insulin Glargine-yfgn Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents… (etiqueta de Insulina glargina, Interacciones medicamentosas)
Drugs That May Decrease the Blood Glucose Lowering Effect of LYUMJEV Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol,… (etiqueta de Insulina lispro, Interacciones medicamentosas)
Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (etiqueta de Ipratropio y salbutamol, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (etiqueta de Ketoconazol, Interacciones medicamentosas)
Diuretics NSAIDs can reduce the natriuretic effect of furosemide and thiazides in some patients. (etiqueta de Ketoprofeno, Advertencias y precauciones)
Diuretics Clinical studies, as well as postmarketing observations, have shown that ketorolac tromethamine can reduce the natriuretic effect of furosemide and thiazides in some patients. (etiqueta de Ketorolaco, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Lansoprazol, Advertencias y precauciones)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
In patients taking ARAVA, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased. (etiqueta de Leflunomida, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etiqueta de Levomilnaciprán, Advertencias y precauciones)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Levorfanol, Interacciones medicamentosas)
Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etiqueta de Levosalbutamol, Interacciones medicamentosas)
Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etiqueta de Furosemida, Interacciones medicamentosas)
Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (etiqueta de Linezolid, Advertencias y precauciones)
Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Lumateperona, Advertencias y precauciones)
Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etiqueta de Lurasidona, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
However, studies with furosemide agents and meloxicam have not demonstrated a reduction in natriuretic effect. (etiqueta de Meloxicam, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (etiqueta de Metadona, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Metilfenidato, Interacciones medicamentosas)
Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Methotrexate and other drugs undergoing renal tubular secretion Furosemide may decrease renal elimination of other drugs that undergo tubular secretion. (etiqueta de Furosemida, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etiqueta de Milnaciprán, Advertencias y precauciones)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etiqueta de Mirtazapina, Advertencias y precauciones)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (etiqueta de Modafinilo, Advertencias y precauciones)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Morfina, Interacciones medicamentosas)
Diuretics: Clinical studies, as well as post marketing observations, have shown that nabumetone can reduce the natriuretic effect of furosemide and thiazides in some patients. (etiqueta de Nabumetona, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Nalbufina, Interacciones medicamentosas)
Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Naproxeno, Interacciones medicamentosas)
Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, those taking diuretics and ACE-inhibitors or ARBs, and the elderly. (etiqueta de Naproxeno y esomeprazol, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
- NiacinaModerada
Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etiqueta de Niacina, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (etiqueta de Nimodipino, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Antihypertensives: Possible additive hypotensive effects. (etiqueta de Nitroglicerina, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
…of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etiqueta de Olanzapina, Advertencias y precauciones)
…and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Olanzapina y fluoxetina, Advertencias y precauciones)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oliceridina, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
- Olmesartán, amlodipino e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol, Advertencias y precauciones)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol y bicarbonato de sodio, Advertencias y precauciones)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Oxaprozina, Interacciones medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oxicodona, Interacciones medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oxicodona y paracetamol, Interacciones medicamentosas)
Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oximorfona, Interacciones medicamentosas)
Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Paliperidona, Advertencias y precauciones)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Pantoprazol, Advertencias y precauciones)
• Hypertension : Patients taking some antihypertensive medications may have impaired response to these therapies when taking NSAIDs. (etiqueta de Paracetamol e ibuprofeno, Advertencias y precauciones)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Paracetamol y codeína, Interacciones medicamentosas)
The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Paricalcitol, Advertencias y precauciones)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (etiqueta de Paroxetina, Advertencias y precauciones)
- PazopanibModerada
Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etiqueta de Pazopanib, Advertencias y precauciones)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Pentazocina y naloxona, Interacciones medicamentosas)
Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etiqueta de Pentoxifilina, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Petidina (meperidina), Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
…danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline),… (etiqueta de Pioglitazona y glimepirida, Interacciones medicamentosas)
Diuretics: NSAIDs can reduce natriuretic effect of furosemide and thiazide diuretics. (etiqueta de Piroxicam, Interacciones medicamentosas)
Reports usually indicate that furosemide ototoxicity is associated with rapid injection, severe renal impairment, the use of higher than recommended doses, hypoproteinemia or concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs. (etiqueta de Furosemida, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)
Diuretics : Codeine may reduce the efficacy of diuretics. (etiqueta de Prometazina y codeína, Interacciones medicamentosas)
Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Quetiapina, Advertencias y precauciones)
Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (etiqueta de Quinidina, Interacciones medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Rabeprazol, Advertencias y precauciones)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etiqueta de Riociguat, Advertencias y precauciones)
Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etiqueta de Risperidona, Advertencias y precauciones)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics: Use with caution. (etiqueta de Salbutamol, Interacciones medicamentosas)
• Diuretics: Use with caution. (etiqueta de Salmeterol, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Sertralina, Advertencias y precauciones)
Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etiqueta de Sildenafilo, Advertencias y precauciones)
However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etiqueta de Silodosina, Advertencias y precauciones)
- SorafenibModerada
Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etiqueta de Sorafenib, Advertencias y precauciones)
Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etiqueta de Sotalol, Advertencias y precauciones)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Drug Interactions In elderly patients concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. (etiqueta de Sulfametoxazol y trimetoprima, Interacciones medicamentosas)
• Salicylates : Risk of salicylate toxicity ( 7.1 ) (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics Clinical studies, as well as post marketing observations, have shown that sulindac can reduce the natriuretic effect of furosemide and thiazides in some patients. (etiqueta de Sulindaco, Interacciones medicamentosas)
Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, salt depletion, those taking diuretics and angiotensin-converting enzyme (ACE) inhibitors or ARBs, and the elderly. (etiqueta de Sumatriptán y naproxeno, Advertencias y precauciones)
- SunitinibModerada
Initiate and/or adjust antihypertensive therapy as appropriate. (etiqueta de Sunitinib, Advertencias y precauciones)
Paralytic agents Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine. (etiqueta de Furosemida, Interacciones medicamentosas)
• Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etiqueta de Tacrolimus, Advertencias y precauciones)
While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the tamsulosin hydrochloride capsules dosage [see Clinical Pharmacology ( 12.3 )] . (etiqueta de Tamsulosina, Interacciones medicamentosas)
…use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tapentadol, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etiqueta de Terbutalina, Precauciones)
In patients taking AUBAGIO, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased. (etiqueta de Teriflunomida, Interacciones medicamentosas)
Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (etiqueta de Furosemida, Interacciones medicamentosas)
In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (etiqueta de Testosterona, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Diuretics: Clinical studies, as well as post-marketing observations have shown that NSAIDs can reduce the natriuretic effect of furosemide and thiazides in some patients. (etiqueta de Tolmetina, Interacciones medicamentosas)
- TolvaptánModerada
Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etiqueta de Tolvaptán, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etiqueta de Toremifeno, Interacciones medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tramadol, Interacciones medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tramadol y paracetamol, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etiqueta de Trazodona, Advertencias y precauciones)
Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (etiqueta de Furosemida, Interacciones medicamentosas)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Trifluoperazina, Precauciones)
• Diuretics: Use with caution. (etiqueta de Umeclidinio y vilanterol, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Angiotensin converting enzyme inhibitors or angiotensin II receptor blockers May lead to severe hypotension and deterioration in renal function, including renal failure. (etiqueta de Furosemida, Interacciones medicamentosas)
Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etiqueta de Vardenafilo, Interacciones medicamentosas)
Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Venlafaxina, Advertencias y precauciones)
Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed. (etiqueta de Furosemida, Interacciones medicamentosas)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Vilazodona, Advertencias y precauciones)
Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etiqueta de Vortioxetina, Advertencias y precauciones)
- Yoduro de potasioModerada
Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etiqueta de Yoduro de potasio, Interacciones medicamentosas)
Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etiqueta de Ziprasidona, Advertencias y precauciones)
Menciones leves (44)
These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel-blocking drugs, and isoniazid. (etiqueta de Acarbosa, Interacciones medicamentosas)
- AmbrisentánLeve
Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etiqueta de Ambrisentán, Advertencias y precauciones)
Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etiqueta de Bosentán, Advertencias y precauciones)
In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs. (etiqueta de Butorfanol, Advertencias)
…Probenecid Probenecid is known to interact with the metabolism or renal tubular excretion of many drugs (e.g., acetaminophen, acyclovir, angiotensin-converting enzyme inhibitors, aminosalicylic acid, barbiturates, benzodiazepines, bumetanide, clofibrate, methotrexate, famotidine, furosemide, nonsteroidal anti-inflammatory agents, theophylline, and zidovudine). (etiqueta de Cidofovir, Interacciones medicamentosas)
- CorticotropinaLeve
Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etiqueta de Corticotropina, Interacciones medicamentosas)
- DasatinibLeve
Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etiqueta de Dasatinib, Advertencias y precauciones)
If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etiqueta de Desogestrel y etinilestradiol, Advertencias)
Antihypertensives Amphetamines may antagonize the hypotensive effects of antihypertensives. (etiqueta de Dexanfetamina, Interacciones medicamentosas)
Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (etiqueta de Dobutamina, Interacciones medicamentosas)
- DocetaxelLeve
Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etiqueta de Docetaxel, Advertencias y precauciones)
Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (etiqueta de Dronedarona, Advertencias y precauciones)
Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (etiqueta de Efedrina, Interacciones medicamentosas)
In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Estrógenos esterificados y metiltestosterona, Advertencias)
…clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (etiqueta de Finasterida, Interacciones medicamentosas)
Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (etiqueta de Flecainida, Interacciones medicamentosas)
These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (etiqueta de Glibenclamida, Interacciones medicamentosas)
Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etiqueta de Glibenclamida y metformina, Interacciones medicamentosas)
Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (etiqueta de Gluconato de calcio, Interacciones medicamentosas)
- HialuronidasaLeve
• Furosemide, the benzodiazepines and phenytoin are incompatible with hyaluronidase ( 7.1 ) (etiqueta de Hialuronidasa, Interacciones medicamentosas)
- IcatibantLeve
ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etiqueta de Icatibant, Interacciones medicamentosas)
Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (etiqueta de Imatinib, Advertencias y precauciones)
Atypical Antipsychotics (e.g., olanzapine and clozapine), Corticosteroids, Danazol, Diuretics, Estrogens, Glucagon, Isoniazid, Niacin, Oral Contraceptives, Phenothiazines, Progestogens (e.g., in oral contraceptives), Protease inhibitors, Somatropin, Sympathomimetic Agents (e.g., albuterol, epinephrine, terbutaline) and Thyroid Hormones. (etiqueta de Insulina regular (humana), Interacciones medicamentosas)
These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (etiqueta de Linagliptina y metformina, Interacciones medicamentosas)
- MacitentánLeve
Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etiqueta de Macitentán, Advertencias y precauciones)
El uso a largo plazo de diuréticos de asa y diuréticos tiazídicos aumenta la pérdida de magnesio por la orina. (NIH Office of Dietary Supplements, Magnesium)
Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etiqueta de Metformina, Interacciones medicamentosas)
Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etiqueta de Metilprednisolona, Interacciones medicamentosas)
In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Metiltestosterona, Advertencias)
In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etiqueta de Mexiletina, Interacciones medicamentosas)
The antihypertensive action of guanethidine and similar agents may be blocked. (etiqueta de Nortriptilina, Advertencias)
These drugs include: aspirin, phenylbutazone, sulfonamides, indomethacin, thiazide diuretics, furosemide and ethacrynic acid. (etiqueta de Penicilina G, Interacciones medicamentosas)
These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etiqueta de Pioglitazona y metformina, Interacciones medicamentosas)
Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (etiqueta de Piperacilina y tazobactam, Advertencias y precauciones)
Los diuréticos de asa y los diuréticos tiazídicos aumentan la pérdida de potasio; a veces se prescribe un suplemento junto con ellos. (NIH Office of Dietary Supplements, Potassium)
Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etiqueta de Prednisolona, Interacciones medicamentosas)
Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etiqueta de Prednisona, Interacciones medicamentosas)
Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etiqueta de Protriptilina, Advertencias)
Examples: Atypical antipsychotics (e.g., olanzapine and clozapine), calcium channel antagonists, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and… (etiqueta de Repaglinida, Interacciones medicamentosas)
These medications include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (etiqueta de Saxagliptina y metformina, Interacciones medicamentosas)
Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (etiqueta de Sitagliptina y metformina, Interacciones medicamentosas)
Potentiation of the action of sulfonylurea hypoglycemic agents, thiazide diuretics and uricosuric agents may also be noted. (etiqueta de Sulfadiazina, Interacciones medicamentosas)
There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (etiqueta de Terbinafina, Interacciones medicamentosas)
Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etiqueta de Triamcinolona, Interacciones medicamentosas)
Sin interacción significativa según la etiqueta (1)
Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etiqueta de Pamidronato, Interacciones medicamentosas)
Compruebe Furosemida frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.
Abrir en el verificadorNo es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.