Metyloprednizolon: interakcje

Metyloprednizolon (Medrol, Solu-Medrol, Depo-Medrol), kortykosteroid: 386 udokumentowanych interakcji w indeksowanych przez nas etykietach FDA i kartach informacyjnych. Poważne: 30, umiarkowane: 271, niewielkie: 84, pary, dla których etykieta nie zgłasza istotnej interakcji: 1. Każda pozycja poniżej cytuje zdanie, na którym się opiera. Ta strona leku to punkt wyjścia, a nie rozstrzygnięcie dla indywidualnej sytuacji.

Interakcje z etykiety

Poważne interakcje (30)

  • Abirateroninhibitor CYP2D6Poważna

    Increased fractures and mortality in combination with radium Ra 223 dichloride: Use of YONSA plus methylprednisolone in combination with radium Ra 223 dichloride is not recommended. (etykieta leku Abirateron, Ostrzeżenia i środki ostrożności)

  • Adalimumablek immunosupresyjnyPoważna

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Adalimumab, Ostrzeżenie w ramce)

  • AdrenalinasympatykomimetykPoważna

    …Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline Epinephrine should not be used to counteract circulatory collapse or hypotension caused by phenothiazines, as a reversal of the pressor effects of epinephrine… (etykieta leku Adrenalina, Interakcje z innymi lekami)

  • AksytynibPoważna

    Withhold INLYTA and avelumab or pembrolizumab, initiate corticosteroid therapy as needed, and/or permanently discontinue the combination for severe or life-threatening hepatotoxicity. (etykieta leku Aksytynib, Ostrzeżenia i środki ostrożności)

  • AlkoholAlkoholPoważna

    DEPO-MEDROL is contraindicated for use in premature infants because the formulation contains benzyl alcohol (see WARNINGS and PRECAUTIONS: Pediatric Use ). (etykieta leku Metyloprednizolon, Przeciwwskazania)

  • Arformoterolagonista receptorów beta-adrenergicznychPoważna

    Use of a LABA, including arformoterol tartrate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma. (etykieta leku Arformoterol, Przeciwwskazania)

  • Atazanawirlek przeciwretrowirusowyPoważna

    Coadministration of fluticasone propionate and REYATAZ with ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects [see Warnings and Precautions (5.1) ] . (etykieta leku Atazanawir, Interakcje z innymi lekami)

  • Baricytynibinhibitor JAKPoważna

    Most patients with rheumatoid arthritis who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Baricytynib, Ostrzeżenie w ramce)

  • DocetakselPoważna

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (etykieta leku Docetaksel, Ostrzeżenia i środki ostrożności)

  • Emtrycytabina + rylpiwiryna + tenofowirlek przeciwretrowirusowyPoważna

    …(5.7) , Drug Interactions (7) , and Clinical Pharmacology (12.3) ]: Anticonvulsants: carbamazepine, oxcarbazepine, phenobarbital, phenytoin Antimycobacterials: rifampin, rifapentine Glucocorticoid (systemic): dexamethasone (more than a single-dose) Herbal Products: St John's wort ( Hypericum perforatum ) Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole,… (etykieta leku Emtrycytabina + rylpiwiryna + tenofowir, Przeciwwskazania)

  • Etanerceptlek immunosupresyjnyPoważna

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Etanercept, Ostrzeżenie w ramce)

  • Formoterolagonista receptorów beta-adrenergicznychPoważna

    Use of a LABA, including formoterol fumarate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma [see Warnings and Precautions (5.1) ]. (etykieta leku Formoterol, Przeciwwskazania)

  • Fosamprenawirlek przeciwretrowirusowyPoważna

    Coadministration of fluticasone and fosamprenavir calcium/ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (etykieta leku Fosamprenawir, Interakcje z innymi lekami)

  • Infliksymablek immunosupresyjnyPoważna

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Infliksymab, Ostrzeżenie w ramce)

  • Ketokonazolazolowy lek przeciwgrzybiczyPoważna

    Fluticasone: Coadministration of fluticasone propionate and ketoconazole is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (etykieta leku Ketokonazol, Interakcje z innymi lekami)

  • LowastatynastatynaPoważna

    Moreover, cholesterol and other products of the cholesterol biosynthesis pathway are essential components for fetal development, including synthesis of steroids and cell membranes. (etykieta leku Lowastatyna, Przeciwwskazania)

  • Mifeprystoninhibitor CYP3A4Poważna

    WARNING: TERMINATION OF PREGNANCY Mifepristone is a potent antagonist of progesterone and cortisol via the progesterone and glucocorticoid (GR-II) receptors, respectively. (etykieta leku Mifepryston, Ostrzeżenie w ramce)

  • Mitotaninduktor CYP3A4Poważna

    If shock, severe trauma or infection occurs or develops, temporarily discontinue LYSODREN and administer exogenous steroids. (etykieta leku Mitotan, Ostrzeżenie w ramce)

  • Moeksyprylinhibitor ACEPoważna

    None of the cases were considered life-threatening and all resolved either without treatment or with medication (antihistamines or glucocorticoids). (etykieta leku Moeksypryl, Ostrzeżenia)

  • Rylpiwirynalek przeciwretrowirusowyPoważna

    Antimycobacterials Rifampin Rifapentine Glucocorticoid (systemic) Dexamethasone (more than a single-dose treatment) Herbal Products St. (etykieta leku Rylpiwiryna, Przeciwwskazania)

  • Salmeterolagonista receptorów beta-adrenergicznychPoważna

    WARNING: ASTHMA-RELATED DEATH Long-acting beta 2 -adrenergic agonists (LABA), such as salmeterol, the active ingredient in SEREVENT DISKUS, as monotherapy (without inhaled corticosteroids [ICS]) increase the risk of asthma-related death. (etykieta leku Salmeterol, Ostrzeżenie w ramce)

  • SomatropinaPoważna

    Intervention: Carefully adjust glucocorticoid dosing in pediatric patients receiving glucocorticoid treatments to avoid both hypoadrenalism and an inhibitory effect on growth. (etykieta leku Somatropina, Interakcje z innymi lekami)

  • Syrolimuslek immunosupresyjnyPoważna

    In a multicenter clinical study, de novo renal transplant patients treated with sirolimus, mycophenolate mofetil (MMF), steroids, and an IL-2 receptor antagonist had significantly higher acute rejection rates and numerically higher death rates compared to patients treated with cyclosporine, MMF, steroids, and IL-2 receptor antagonist. (etykieta leku Syrolimus, Ostrzeżenia i środki ostrożności)

  • Tocilizumablek immunosupresyjnyPoważna

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Tocilizumab, Ostrzeżenie w ramce)

  • Tofacytyniblek immunosupresyjnyPoważna

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Tofacytynib, Ostrzeżenie w ramce)

  • Trandolaprylinhibitor ACEPoważna

    Two of the four cases were life-threatening and resolved without treatment or with medication (corticosteroids). (etykieta leku Trandolapryl, Ostrzeżenia)

  • TretynoinaretinoidPoważna

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (etykieta leku Tretynoina, Ostrzeżenie w ramce)

  • Trójtlenek arsenulek wydłużający odstęp QTPoważna

    If differentiation syndrome is suspected, immediately initiate high-dose corticosteroids and hemodynamic monitoring until resolution. (etykieta leku Trójtlenek arsenu, Ostrzeżenie w ramce)

  • Umeklidynium + wilanterollek przeciwcholinergicznyPoważna

    • use of a long-acting beta 2 -adrenergic agonist (LABA), including vilanterol, one of the active ingredients in Umeclidinium and Vilanterol ELLIPTA, without an inhaled corticosteroid (ICS), in patients with asthma [see Warnings and Precautions ( 5.1 )] . (etykieta leku Umeklidynium + wilanterol, Przeciwwskazania)

  • Upadacytyniblek immunosupresyjnyPoważna

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (etykieta leku Upadacytynib, Ostrzeżenie w ramce)

Umiarkowane interakcje (271)

  • AfatynibUmiarkowana

    Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (etykieta leku Afatynib, Ostrzeżenia i środki ostrożności)

  • Akarbozalek przeciwcukrzycowyUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Aklidyniumlek przeciwcholinergicznyUmiarkowana

    Sympathomimetics, Methylxanthines, Steroids In clinical studies, concurrent administration of aclidinium bromide and other drugs commonly used in the treatment of COPD including sympathomimetics (short-acting beta 2 agonists), methylxanthines, and oral and inhaled steroids showed no increases in adverse drug reactions. (etykieta leku Aklidynium, Interakcje z innymi lekami)

  • AlbendazolUmiarkowana

    Risk of Neurologic Symptoms: Neurocysticercosis patients may experience cerebral hypertensive episodes, seizures or focal neurologic deficits after initiation of therapy; begin appropriate steroid and anticonvulsant therapy. (etykieta leku Albendazol, Ostrzeżenia i środki ostrożności)

  • Alemtuzumablek immunosupresyjnyUmiarkowana

    Institute appropriate medical management (e.g., glucocorticoids, epinephrine, meperidine) for infusion-related reactions as needed [see Dosage and Administration (2.2) ] . (etykieta leku Alemtuzumab, Ostrzeżenia i środki ostrożności)

  • Aliskirenlek przeciwnadciśnieniowyUmiarkowana

    Patients who experience these effects, even without respiratory distress, require prolonged observation and appropriate monitoring measures since treatment with antihistamines and corticosteroids may not be sufficient to prevent respiratory involvement. (etykieta leku Aliskiren, Ostrzeżenia i środki ostrożności)

  • Alogliptynainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Alogliptyna + metforminainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • AlpelisybUmiarkowana

    If a SCAR is not confirmed, VIJOICE may require dose modifications, topical or systemic corticosteroids, or oral antihistamine treatment as described in Table 4 [see Dosage and Administration (2.5)] . (etykieta leku Alpelisyb, Ostrzeżenia i środki ostrożności)

  • Amfoterycyna Blek przeciwgrzybiczyUmiarkowana

    There have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure (see CONTRAINDICATIONS and PRECAUTIONS: Drug Interactions, Amphotericin B injection and potassium-depleting agents ). (etykieta leku Metyloprednizolon, Ostrzeżenia)

  • Apiksabanlek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Aprepitantinhibitor CYP3A4Umiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Argatrobanlek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Armodafinillek pobudzający OUNUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Azytromycynaantybiotyk makrolidowyUmiarkowana

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • BalsalazydsalicylanUmiarkowana

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • BeklometazonkortykosteroidUmiarkowana

    Lung function (FEV 1 or PEF), beta‑agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral or other systemic corticosteroids. (etykieta leku Beklometazon, Ostrzeżenia i środki ostrożności)

  • BendamustynaUmiarkowana

    Consider measures to prevent severe reactions, including antihistamines, antipyretics and corticosteroids in subsequent cycles in patients who have experienced Grade 1 or 2 infusion reactions. (etykieta leku Bendamustyna, Ostrzeżenia i środki ostrożności)

  • BenralizumabUmiarkowana

    • Reduction in Corticosteroid Dosage: Do not discontinue systemic or inhaled corticosteroids abruptly upon initiation of therapy with FASENRA. (etykieta leku Benralizumab, Ostrzeżenia i środki ostrożności)

  • Bexagliflozininhibitor SGLT2Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Biktegrawir + emtrycytabina + alafenamid tenofowirulek przeciwretrowirusowyUmiarkowana

    Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) ↓ lenacapavir (dexamethasone) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (etykieta leku Biktegrawir + emtrycytabina + alafenamid tenofowiru, Interakcje z innymi lekami)

  • Biwalirudynalek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Bosentaninduktor CYP3A4Umiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Budezonid + formoterolkortykosteroidUmiarkowana

    In this situation, the patient requires immediate re-evaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of budesonide and formoterol fumarate dihydrate with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (etykieta leku Budezonid + formoterol, Ostrzeżenia i środki ostrożności)

  • BuprenorfinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Buprenorfina, Ostrzeżenia i środki ostrożności)

  • Buprenorfina + naloksonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Buprenorfina + nalokson, Ostrzeżenia i środki ostrożności)

  • Bupropionlek przeciwdepresyjnyUmiarkowana

    …risk of seizure: concomitant use of other medications that lower the seizure threshold (e.g., other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, and systemic corticosteroids), metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia), or use of illicit drugs (e.g., cocaine) or abuse or misuse… (etykieta leku Bupropion, Ostrzeżenia i środki ostrożności)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Butalbital + paracetamolbarbituranUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • ButorfanolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Butorfanol, Ostrzeżenia)

  • CefoksytynacefalosporynaUmiarkowana

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (etykieta leku Cefoksytyna, Ostrzeżenia i środki ostrożności)

  • CelekoksybNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Cenobamatlek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Cyklosporynalek immunosupresyjnyUmiarkowana

    Cyclosporine : Increased activity of both cyclosporine and corticosteroids may occur when the two are used concurrently. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • CyprofloksacynafluorochinolonUmiarkowana

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Cyprofloksacyna, Ostrzeżenia i środki ostrożności)

  • CytarabinaantymetabolitUmiarkowana

    These reactions include reversible corneal toxicity, and hemorrhagic conjunctivitis, which may be prevented or diminished by prophylaxis with a local corticosteroid eye drop; cerebral and cerebellar dysfunction, including personality changes, somnolence and coma, usually reversible; severe gastrointestinal ulceration, including pneumatosis cystoides intestinalis… (etykieta leku Cytarabina, Ostrzeżenia)

  • Dabigatranlek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Dapagliflozynainhibitor SGLT2Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Dapagliflozyna + metforminainhibitor SGLT2Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • DaptomycynaantybiotykUmiarkowana

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (etykieta leku Daptomycyna, Ostrzeżenia i środki ostrożności)

  • Darunawirlek przeciwretrowirusowyUmiarkowana

    Corticosteroids primarily metabolized by CYP3A: e.g. betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone ↑ corticosteroids Co-administration with corticosteroids (all routes of administration) of which exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal… (etykieta leku Darunawir, Interakcje z innymi lekami)

  • Darunawir + kobicystatlek przeciwretrowirusowyUmiarkowana

    Corticosteroids: dexamethasone (systemic) Corticosteroids primarily metabolized by CYP3A: e.g. betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone ↓ darunavir ↓ cobicistat ↑ corticosteroids Co-administration with systemic dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic… (etykieta leku Darunawir + kobicystat, Interakcje z innymi lekami)

  • Deferazyrokssuplement żelazaUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • DeksametazonkortykosteroidUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • DenosumabUmiarkowana

    Other risk factors for the development of ONJ include immunosuppressive therapy, treatment with angiogenesis inhibitors, systemic corticosteroids, diabetes, and gingival infections. (etykieta leku Denosumab, Ostrzeżenia i środki ostrożności)

  • Dezogestrel + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Dicyklowerynalek przeciwcholinergicznyUmiarkowana

    Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corticosteroids. (etykieta leku Dicykloweryna, Interakcje z innymi lekami)

  • DiflunisalNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Digoksynaglikozyd naparstnicyUmiarkowana

    Digitalis glycosides : Patients on digitalis glycosides may be at increased risk of arrhythmias due to hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • DiklofenakNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Dioctan etynodiolu + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Drospirenon + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Dulaglutydagonista receptora GLP-1Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • DupilumabUmiarkowana

    Eosinophilic Conditions: Be alert to vasculitic rash, worsening pulmonary symptoms, cardiac complications, kidney injury and/or neuropathy, especially upon reduction of oral corticosteroids. (etykieta leku Dupilumab, Ostrzeżenia i środki ostrożności)

  • Edoksabanlek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Efawirenzlek przeciwretrowirusowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Efawirenz + lamiwudyna + tenofowirlek przeciwretrowirusowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Eksenatydagonista receptora GLP-1Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Although other risk factors were present in some cases (such as corticosteroid use, exposure to radiation), a possible risk attributable to treatment with ivacaftor cannot be excluded. (etykieta leku Eleksakaftor + tezakaftor + iwakaftor, Ostrzeżenia i środki ostrożności)

  • Corticosteroids: e.g., betamethasone budesonide ciclesonide dexamethasone fluticasone methylprednisolone mometasone prednisone triamcinolone ↓ elvitegravir ↓ cobicistat ↑ corticosteroids Coadministration with oral dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic effect and development of resistance to elvitegravir. (etykieta leku Elwitegrawir + kobicystat + emtrycytabina + tenofowir, Interakcje z innymi lekami)

  • Empagliflozynainhibitor SGLT2Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Empagliflozyna + metforminainhibitor SGLT2Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Enoksaparynalek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • ErlotynibUmiarkowana

    Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (etykieta leku Erlotynib, Ostrzeżenia i środki ostrożności)

  • Erytromycynaantybiotyk makrolidowyUmiarkowana

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Eslikarbazepinalek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • EstradiolestrogenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Estradiol + dienogestdoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Estradiol + noretysteronestrogenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Estrogeny skoniugowaneestrogenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • EtodolakNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Etrawirynalek przeciwretrowirusowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • FenobarbitalbarbituranUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • FenoprofenNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • FentanylopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Fentanyl, Ostrzeżenia i środki ostrożności)

  • Fentermina + topiramatlek pobudzający OUNUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Fenylefrynalek obkurczający błonę śluzową nosaUmiarkowana

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (etykieta leku Fenylefryna, Interakcje z innymi lekami)

  • Corticosteroids, valproic acid, or haloperidol : May increase plasma ammonia level; monitor ammonia levels closely. (etykieta leku Fenylomaślan glicerolu, Interakcje z innymi lekami)

  • Valproic Acid, Haloperidol, or Corticosteroids : May increase plasma ammonia level; monitor ammonia levels closely. (etykieta leku Fenylomaślan sodu, Interakcje z innymi lekami)

  • Use of corticosteroids may cause a protein catabolic state and, thereby, potentially increase plasma ammonia levels in patients with impaired ability to form urea. (etykieta leku Fenylooctan sodu + benzoesan sodu, Interakcje z innymi lekami)

  • Fenytoinalek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Fidaksomycynaantybiotyk makrolidowyUmiarkowana

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Fingolimodlek immunosupresyjnyUmiarkowana

    In both cases, the patients were taking a 1.25 mg dose of fingolimod (higher than the recommended 0.5 mg dose) and had received high-dose corticosteroid therapy to treat suspected MS relapses. (etykieta leku Fingolimod, Ostrzeżenia i środki ostrożności)

  • FlunizolidkortykosteroidUmiarkowana

    Pregnancy As with other corticosteroids, flunisolide has been shown to be teratogenic and fetotoxic in rabbits and rats at oral doses of 40 and 200 mcg/kg/day, respectively (approximately 2 and 4 times, respectively, the maximum recommended daily intranasal dose in adults on a mg/m 2 basis). (etykieta leku Flunizolid, Środki ostrożności)

  • FluocynonidkortykosteroidUmiarkowana

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic absorption of topical corticosteroids. (etykieta leku Fluocynonid, Ostrzeżenia i środki ostrożności)

  • FlurbiprofenNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Flutykazon + salmeterolkortykosteroidUmiarkowana

    In this situation, the patient requires immediate reevaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of Fluticasone Propionate/Salmeterol MDPI with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (etykieta leku Flutykazon + salmeterol, Ostrzeżenia i środki ostrożności)

  • Fondaparynukslek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Fosaprepitantinhibitor CYP3A4Umiarkowana

    Methylprednisolone Clinical Impact Increased methylprednisolone exposure [see Clinical Pharmacology ( 12.3 )]. (etykieta leku Fosaprepitant, Interakcje z innymi lekami)

  • Fosfenytoinalek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • FulwestrantestrogenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Glibenklamidpochodna sulfonylomocznikaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Glibenklamid + metforminapochodna sulfonylomocznikaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Glimepirydpochodna sulfonylomocznikaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Glipizydpochodna sulfonylomocznikaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Glipizyd + metforminapochodna sulfonylomocznikaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Gryzeofulwinalek przeciwgrzybiczyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • HalobetazolkortykosteroidUmiarkowana

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic exposure to topical corticosteroids. (etykieta leku Halobetazol, Ostrzeżenia i środki ostrożności)

  • Haloperydollek przeciwpsychotycznyUmiarkowana

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etykieta leku Haloperydol, Interakcje z innymi lekami)

  • Heparynalek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Hydralazynalek rozszerzający naczyniaUmiarkowana

    Long-term treatment with steroids may be necessary (see PRECAUTIONS, Laboratory Tests ). (etykieta leku Hydralazyna, Ostrzeżenia)

  • HydrokodonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon, Ostrzeżenia i środki ostrożności)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon + chlorfenamina, Ostrzeżenia i środki ostrożności)

  • Hydrokodon + homatropinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon + homatropina, Ostrzeżenia i środki ostrożności)

  • Hydrokodon + ibuprofenopioidUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Hydrokodon + paracetamolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydrokodon + paracetamol, Ostrzeżenia)

  • HydrokortyzonkortykosteroidUmiarkowana

    There have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure (see CONTRAINDICATIONS and PRECAUTIONS: Drug Interactions, Amphotericin B injection and potassium-depleting agents ). (etykieta leku Metyloprednizolon, Ostrzeżenia)

  • HydromorfonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Hydromorfon, Ostrzeżenia i środki ostrożności)

  • IbuprofenNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Ibuprofen + famotydynaNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Imatynibinhibitor CYP3A4Umiarkowana

    If either is abnormal, consider prophylactic use of systemic steroids (1-2 mg/kg) for one to two weeks concomitantly with Gleevec at the initiation of therapy. (etykieta leku Imatynib, Ostrzeżenia i środki ostrożności)

  • IndometacynaNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Insulina aspartinsulinaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Insulina degludecinsulinaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Insulina detemirinsulinaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Insulina glargineinsulinaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Insulina lisproinsulinaUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Itrakonazolazolowy lek przeciwgrzybiczyUmiarkowana

    Budesonide (inhalation) Budesonide (noninhalation) Ciclesonide (inhalation) Cyclosporine (IV) Cyclosporine (non-IV) Dexamethasone Fluticasone (inhalation) Fluticasone (nasal) Methylprednisolone Tacrolimus (IV) Tacrolimus (oral) Monitor for adverse reactions. (etykieta leku Itrakonazol, Interakcje z innymi lekami)

  • Iwakaftorinhibitor CYP3A4Umiarkowana

    Although other risk factors were present in some cases (such as corticosteroid use and/or exposure to radiation), a possible risk attributable to KALYDECO cannot be excluded. (etykieta leku Iwakaftor, Ostrzeżenia i środki ostrożności)

  • IwermektynaUmiarkowana

    Oral hydration, recumbency, intravenous normal saline, and/or parenteral corticosteroids have been used to treat postural hypotension. (etykieta leku Iwermektyna, Ostrzeżenia)

  • IzoniazydantybiotykUmiarkowana

    Antitubercular drugs : Serum concentrations of isoniazid may be decreased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kanagliflozynainhibitor SGLT2Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Karbamazepinalek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • KetoprofenNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • KetorolakNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • KladrybinaantymetabolitUmiarkowana

    Prevention or Management Consider a possible decrease in cladribine efficacy if potent BCRP (e.g., corticosteroids) or P-gp (e.g., rifampicin, St. (etykieta leku Kladrybina, Interakcje z innymi lekami)

  • Klarytromycynaantybiotyk makrolidowyUmiarkowana

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • KlobazambenzodiazepinaUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • KodeinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Kodeina, Ostrzeżenia i środki ostrożności)

  • Kokainaśrodek znieczulający miejscowoUmiarkowana

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (etykieta leku Kokaina, Interakcje z innymi lekami)

  • Kolestyraminasekwestrant kwasów żółciowychUmiarkowana

    Cholestyramine : Cholestyramine may increase the clearance of oral corticosteroids. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kwas acetylosalicylowyNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kwas acetylosalicylowy + dipirydamollek przeciwpłytkowyUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kwas alendronowybisfosfonianUmiarkowana

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (etykieta leku Kwas alendronowy, Ostrzeżenia i środki ostrożności)

  • Kwas ibandronowybisfosfonianUmiarkowana

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (etykieta leku Kwas ibandronowy, Ostrzeżenia i środki ostrożności)

  • Kwas mefenamowyNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kwas pamidronowybisfosfonianUmiarkowana

    Many of these patients were also receiving chemotherapy and corticosteroids, which may be risk factors for ONJ. (etykieta leku Kwas pamidronowy, Ostrzeżenia i środki ostrożności)

  • Kwas ryzedronowybisfosfonianUmiarkowana

    …the jaw include invasive dental procedures (for example, tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (for example, chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (for example, periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection,… (etykieta leku Kwas ryzedronowy, Ostrzeżenia i środki ostrożności)

  • Kwas walproinowylek przeciwdrgawkowyUmiarkowana

    Oral Contraceptive Steroids Administration of a single-dose of ethinyloestradiol (50 mcg)/levonorgestrel (250 mcg) to 6 women on valproate (200 mg BID) therapy for 2 months did not reveal any pharmacokinetic interaction. (etykieta leku Kwas walproinowy, Interakcje z innymi lekami)

  • Kwas zoledronowybisfosfonianUmiarkowana

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (etykieta leku Kwas zoledronowy, Ostrzeżenia i środki ostrożności)

  • Lenakapawirlek przeciwretrowirusowyUmiarkowana

    Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (etykieta leku Lenakapawir, Interakcje z innymi lekami)

  • LewofloksacynafluorochinolonUmiarkowana

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients usually over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Lewofloksacyna, Ostrzeżenia i środki ostrożności)

  • LewonorgestrelprogestagenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Lewonorgestrel + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • LeworfanolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Leworfanol, Ostrzeżenia)

  • Lewosalbutamolagonista receptorów beta-adrenergicznychUmiarkowana

    If the patient needs more doses of XOPENEX HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (etykieta leku Lewosalbutamol, Ostrzeżenia i środki ostrożności)

  • Lewotyroksynahormon tarczycyUmiarkowana

    Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etykieta leku Lewotyroksyna, Ostrzeżenia i środki ostrożności)

  • Lewotyroksyna + liotyroninahormon tarczycyUmiarkowana

    The therapy of myxedema coma requires simultaneous administration of glucocorticoids (See DOSAGE AND ADMINISTRATION). (etykieta leku Lewotyroksyna + liotyronina, Środki ostrożności)

  • Linagliptynainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Linagliptyna + metforminainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Liotyroninahormon tarczycyUmiarkowana

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (etykieta leku Liotyronina, Ostrzeżenia i środki ostrożności)

  • Liraglutydagonista receptora GLP-1Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Lizynopryl + hydrochlorotiazydinhibitor ACEUmiarkowana

    Even in those instances where swelling of only the tongue is involved, without respiratory distress, patients may require prolonged observation since treatment with antihistamines and corticosteroids may not be sufficient. (etykieta leku Lizynopryl + hydrochlorotiazyd, Ostrzeżenia)

  • Lopinawir + rytonawirlek przeciwretrowirusowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Lorlatynibinduktor CYP3A4Umiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MargetuximabUmiarkowana

    In patients who experience mild or moderate IRRs, consider premedications, including antihistamines, corticosteroids, and antipyretics. (etykieta leku Margetuximab, Ostrzeżenia i środki ostrożności)

  • MedroksyprogesteronprogestagenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MegestrolprogestagenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MeloksykamNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Mentol + salicylan metylusalicylanUmiarkowana

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MepolizumabUmiarkowana

    Decrease corticosteroids gradually, if appropriate. (etykieta leku Mepolizumab, Ostrzeżenia i środki ostrożności)

  • MesalazynasalicylanUmiarkowana

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MetadonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Metadon, Ostrzeżenia i środki ostrożności)

  • Metazolamidinhibitor anhydrazy węglanowejUmiarkowana

    Drug Interactions Methazolamide should be used with caution in patients on steroid therapy because of the potential for developing hypokalemia. (etykieta leku Metazolamid, Interakcje z innymi lekami)

  • MetforminabiguanidUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MetoheksitalbarbituranUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Metolazondiuretyk tiazydowyUmiarkowana

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (etykieta leku Metolazon, Interakcje z innymi lekami)

  • Metotreksatlek immunosupresyjnyUmiarkowana

    NSAIDs, Aspirin, and Steroids: May elevate and prolong serum methotrexate levels and increase gastrointestinal toxicity. (etykieta leku Metotreksat, Interakcje z innymi lekami)

  • Metyldopalek przeciwnadciśnieniowyUmiarkowana

    If not, corticosteroids may be given and other causes of anemia should be considered. (etykieta leku Metyldopa, Ostrzeżenia)

  • MetylotestosteronandrogenUmiarkowana

    Testosterone has been subject to abuse, typically at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids. (etykieta leku Metylotestosteron, Ostrzeżenia)

  • MetyraponUmiarkowana

    This can be corrected by giving appropriate doses of corticosteroids. (etykieta leku Metyrapon, Ostrzeżenia i środki ostrożności)

  • Miglitollek przeciwcukrzycowyUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Mitapiwatinduktor CYP3A4Umiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Modafinillek pobudzający OUNUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MoksyfloksacynafluorochinolonUmiarkowana

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Moksyfloksacyna, Ostrzeżenia i środki ostrożności)

  • MometazonkortykosteroidUmiarkowana

    Lung function (FEV 1 or PEF), beta-agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral or other systemic corticosteroids. (etykieta leku Mometazon, Ostrzeżenia i środki ostrożności)

  • Montelukastantagonista receptora leukotrienowegoUmiarkowana

    Inhaled corticosteroid may be reduced gradually. (etykieta leku Montelukast, Ostrzeżenia i środki ostrożności)

  • MorfinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Morfina, Ostrzeżenia i środki ostrożności)

  • NabumetonNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Nafcylinaantybiotyk penicylinowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • NalbufinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Nalbufina, Ostrzeżenia)

  • Naltrekson + bupropionantagonista receptorów opioidowychUmiarkowana

    …hypoglycemia concomitant administration of medications that may lower the seizure threshold, including other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, systemic steroids Recommendations for Reducing the Risk of Seizure: Clinical experience with bupropion suggests that the risk of seizure may be minimized by adhering to the recommended… (etykieta leku Naltrekson + bupropion, Ostrzeżenia i środki ostrożności)

  • NaproksenNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Natalizumablek immunosupresyjnyUmiarkowana

    In Studies MS1 and MS2, an increase in infections was seen in patients concurrently receiving short courses of corticosteroids. (etykieta leku Natalizumab, Ostrzeżenia i środki ostrożności)

  • NateglinidmeglitynidUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Newirapinalek przeciwretrowirusowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • NintedanibUmiarkowana

    Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (etykieta leku Nintedanib, Ostrzeżenia i środki ostrożności)

  • Nirmatrelwir + rytonawirlek przeciwwirusowyUmiarkowana

    Corticosteroids primarily metabolized by CYP3A betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, triamcinolone ↑ corticosteroid Co-administration with corticosteroids (all routes of administration) of which exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing’s syndrome… (etykieta leku Nirmatrelwir + rytonawir, Interakcje z innymi lekami)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • NoretysteronprogestagenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Noretysteron + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Norgestrel + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Norgestymat + etynyloestradioldoustny środek antykoncepcyjnyUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • OfloksacynafluorochinolonUmiarkowana

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (etykieta leku Ofloksacyna, Ostrzeżenia)

  • Okrelizumablek immunosupresyjnyUmiarkowana

    In multiple sclerosis (MS) clinical trials, all adult and pediatric patients who were treated with OCREVUS received premedication with methylprednisolone (or an equivalent steroid), and may have also received an antihistamine (all pediatric patients) and/or an analgesic/antipyretic to reduce the risk of infusion reactions prior to each infusion. (etykieta leku Okrelizumab, Ostrzeżenia i środki ostrożności)

  • OksaprozynaNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Okskarbazepinalek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • OksykodonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Oksykodon, Ostrzeżenia i środki ostrożności)

  • Oksykodon + paracetamolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Oksykodon + paracetamol, Ostrzeżenia i środki ostrożności)

  • OksymorfonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Oksymorfon, Ostrzeżenia i środki ostrożności)

  • OlicerydynaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Olicerydyna, Ostrzeżenia i środki ostrożności)

  • OmalizumabUmiarkowana

    Corticosteroid Reduction: Do not abruptly discontinue corticosteroids upon initiation of OMLYCLO therapy. (etykieta leku Omalizumab, Ostrzeżenia i środki ostrożności)

  • Orfenadryna + kwas acetylosalicylowy + kofeinalek zwiotczający mięśnieUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Paracetamol + kodeinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Paracetamol + kodeina, Ostrzeżenia)

  • PasyreotydUmiarkowana

    If adrenal insufficiency is suspected, it should be confirmed and treated per standard of care with exogenous glucocorticoids at replacement doses . (etykieta leku Pasyreotyd, Ostrzeżenia i środki ostrożności)

  • PenicylaminaUmiarkowana

    Treatment has consisted of high doses of corticosteroids alone or, in some cases, concomitantly with an immunosuppressant. (etykieta leku Penicylamina, Ostrzeżenia)

  • Pentazocyna + naloksonopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Pentazocyna + nalokson, Ostrzeżenia)

  • PetydynaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Petydyna, Ostrzeżenia i środki ostrożności)

  • PioglitazontiazolidynodionUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Pioglitazon + glimepirydtiazolidynodionUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Pioglitazon + metforminatiazolidynodionUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • PiroksykamNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Pokrzyk wilcza jagoda (belladonna) + opium, Ostrzeżenia i środki ostrożności)

  • Ponesimodlek immunosupresyjnyUmiarkowana

    Prior and Concomitant Treatment with Anti-neoplastic, Immune-Modulating, or Immunosuppressive Therapies Anti-neoplastic, immune-modulating, or immunosuppressive therapies (including corticosteroids) should be coadministered with caution because of the risk of additive immune system effects [see Drug Interactions (7.1) ] . (etykieta leku Ponesimod, Ostrzeżenia i środki ostrożności)

  • ProgesteronprogestagenUmiarkowana

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Prometazyna + kodeinaopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Prometazyna + kodeina, Ostrzeżenia i środki ostrożności)

  • Propofollek działający depresyjnie na OUNUmiarkowana

    The following appear to be major risk factors for the development of these events: decreased oxygen delivery to tissues; serious neurological injury and/or sepsis; high dosages of one or more of the following pharmacological agents: vasoconstrictors, steroids, inotropes and/or prolonged, high-dose infusions of propofol (> 5 mg/kg/hour for > 48 hours). (etykieta leku Propofol, Ostrzeżenia i środki ostrożności)

  • Prymidonlek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • RepaglinidmeglitynidUmiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Rokuroniumlek blokujący przewodnictwo nerwowo-mięśnioweUmiarkowana

    Therefore, for patients receiving both neuromuscular blocking agents (including Rocuronium Bromide Injection) and corticosteroids, the period of use of the neuromuscular blocking agent should be limited as much as possible and only used in the setting where in the opinion of the prescribing physician, the specific advantages of the drug outweigh the risk. (etykieta leku Rokuronium, Ostrzeżenia i środki ostrożności)

  • RyfabutynaantybiotykUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • RyfampicynaantybiotykUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • RyfapentynaantybiotykUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Rytonawirlek przeciwretrowirusowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Rywaroksabanlek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Saksagliptynainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Saksagliptyna + metforminainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Salbutamolagonista receptorów beta-adrenergicznychUmiarkowana

    If the patient needs more doses of Albuterol Sulfate HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (etykieta leku Salbutamol, Ostrzeżenia i środki ostrożności)

  • SalsalatNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Semaglutydagonista receptora GLP-1Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Suksametoniumlek blokujący przewodnictwo nerwowo-mięśnioweUmiarkowana

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (etykieta leku Suksametonium, Interakcje z innymi lekami)

  • SulfasalazynasulfonamidUmiarkowana

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • SulindakNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Sumatryptan + naproksentryptanUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Suzetryginainduktor CYP3A4Umiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Sytagliptynainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Sytagliptyna + metforminainhibitor DPP-4Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Takrolimuslek immunosupresyjnyUmiarkowana

    Mild or Moderate CYP3A Inducers Methylprednisolone, prednisone May decrease tacrolimus whole blood trough concentrations. (etykieta leku Takrolimus, Interakcje z innymi lekami)

  • TapentadolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Tapentadol, Ostrzeżenia i środki ostrożności)

  • TemozolomidUmiarkowana

    Pneumocystis Pneumonia (PCP) : Closely monitor all patients, particularly those receiving steroids, for the development of lymphopenia and PCP. (etykieta leku Temozolomid, Ostrzeżenia i środki ostrożności)

  • TemsyrolimusUmiarkowana

    If ILD is suspected, discontinue TORISEL, and consider use of corticosteroids and/or antibiotics. (etykieta leku Temsyrolimus, Ostrzeżenia i środki ostrożności)

  • TeofilinametyloksantynaUmiarkowana

    Dosage Increases: Increases in the dose of theophylline should not be made in response to an acute exacerbation of symptoms of chronic lung disease since theophylline provides little added benefit to inhaled beta2 -selective agonists and systemically administered corticosteroids in this circumstance and increases the risk of adverse effects. (etykieta leku Teofilina, Ostrzeżenia)

  • Terbutalinaagonista receptorów beta-adrenergicznychUmiarkowana

    If the patient needs more doses of terbutaline sulfate tablets than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and the treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (etykieta leku Terbutalina, Ostrzeżenia)

  • Teryparatydhormon tarczycyUmiarkowana

    Risk factors for development of calciphylaxis include underlying auto-immune disease, kidney failure, and concomitant warfarin or systemic corticosteroid use. (etykieta leku Teryparatyd, Ostrzeżenia i środki ostrożności)

  • TesamorelinaUmiarkowana

    Glucocorticoids : Patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA SV. (etykieta leku Tesamorelina, Interakcje z innymi lekami)

  • TestosteronandrogenUmiarkowana

    Abuse of Testosterone and Monitoring of Serum Testosterone : If testosterone use at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids is suspected, check serum testosterone concentration ( 5.5 ). (etykieta leku Testosteron, Ostrzeżenia i środki ostrożności)

  • Tiotropiumlek przeciwcholinergicznyUmiarkowana

    Concomitant Respiratory Medications SPIRIVA RESPIMAT has been used concomitantly with short-acting and long-acting sympathomimetic (beta-agonists) bronchodilators, methylxanthines, oral and inhaled steroids, antihistamines, mucolytics, leukotriene modifiers, cromones, and anti-IgE treatment without increases in adverse reactions. (etykieta leku Tiotropium, Interakcje z innymi lekami)

  • TolmetynaNLPZUmiarkowana

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Topiramatlek przeciwdrgawkowyUmiarkowana

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Torasemiddiuretyk pętlowyUmiarkowana

    Corticosteroids and ACTH: Increased risk of hypokalemia. (etykieta leku Torasemid, Interakcje z innymi lekami)

  • TramadolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Tramadol, Ostrzeżenia i środki ostrożności)

  • Tramadol + paracetamolopioidUmiarkowana

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (etykieta leku Tramadol + paracetamol, Ostrzeżenia i środki ostrożności)

  • TrastuzumabUmiarkowana

    Interrupt TRAZIMERA infusion in all patients experiencing dyspnea, clinically significant hypotension, and intervention of medical therapy administered (which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators, and oxygen). (etykieta leku Trastuzumab, Ostrzeżenia i środki ostrożności)

  • TriamcynolonkortykosteroidUmiarkowana

    Results from one multicenter, randomized, placebo-controlled study with methylprednisolone hemisuccinate, an intravenous corticosteroid, showed an increase in early (at 2 weeks) and late (at 6 months) mortality in patients with cranial trauma who were determined not to have other clear indications for corticosteroid treatment. (etykieta leku Triamcynolon, Ostrzeżenia)

  • Triamteren + hydrochlorotiazyddiuretyk oszczędzający potasUmiarkowana

    Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (etykieta leku Triamteren + hydrochlorotiazyd, Interakcje z innymi lekami)

  • Tyrzepatydagonista receptora GLP-1Umiarkowana

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Warfarynalek przeciwzakrzepowyUmiarkowana

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Worykonazolazolowy lek przeciwgrzybiczyUmiarkowana

    • Adrenal Dysfunction : Carefully monitor patients receiving voriconazole and corticosteroids (via all routes of administration) for adrenal dysfunction both during and after voriconazole treatment. (etykieta leku Worykonazol, Ostrzeżenia i środki ostrożności)

  • Zasadowy salicylan bizmutusalicylanUmiarkowana

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • ZenocutuzumabUmiarkowana

    Prior to the first BIZENGRI infusion, premedicate with a corticosteroid, an H1 antihistamine and acetaminophen to reduce the risk of IRRs [see Dosage and Administration (2.4) ]. (etykieta leku Zenocutuzumab, Ostrzeżenia i środki ostrożności)

Wzmianki o niewielkim znaczeniu (84)

  • Acetazolamidinhibitor anhydrazy węglanowejNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • AlteplazaNiewielka

    If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy (e.g., antihistamines, intravenous corticosteroids, epinephrine). (etykieta leku Alteplaza, Ostrzeżenia i środki ostrożności)

  • Amfetaminalek pobudzający OUNNiewielka

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Amfetamina, Interakcje z innymi lekami)

  • Amfetamina + deksamfetaminalek pobudzający OUNNiewielka

    Interference with Laboratory Tests Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Amfetamina + deksamfetamina, Interakcje z innymi lekami)

  • AmikacynaaminoglikozydNiewielka

    Most patients with hypersensitivity pneumonitis discontinued treatment with ARIKAYCE and received treatment with corticosteroids [see Adverse Reactions (6.1) ] . (etykieta leku Amikacyna, Ostrzeżenia i środki ostrożności)

  • Amiloryddiuretyk oszczędzający potasNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Amiodaronlek przeciwarytmicznyNiewielka

    Antithyroid drugs, β-adrenergic blockers, temporary corticosteroid therapy may be necessary to treat the symptoms of hyperthyroidism. (etykieta leku Amiodaron, Ostrzeżenia i środki ostrożności)

  • Ampicylinaantybiotyk penicylinowyNiewielka

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (etykieta leku Ampicylina, Ostrzeżenia)

  • Atenolol + chlortalidonbeta-blokerNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Benazepryl + hydrochlorotiazydinhibitor ACENiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Benzylopenicylinaantybiotyk penicylinowyNiewielka

    Oxygen, intravenous steroids, and airway management, including intubation, should also be administered as indicated. (etykieta leku Benzylopenicylina, Ostrzeżenia)

  • BewacyzumabNiewielka

    Discontinue in patients who develop a severe infusion-related reaction and administer appropriate medical therapy (e.g., epinephrine, corticosteroids, intravenous antihistamines, bronchodilators and/or oxygen). (etykieta leku Bewacyzumab, Ostrzeżenia i środki ostrożności)

  • Bisoprolol + hydrochlorotiazydbeta-blokerNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Bumetaniddiuretyk pętlowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • BusulfanNiewielka

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (etykieta leku Busulfan, Ostrzeżenia)

  • CefadroksylcefalosporynaNiewielka

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefadroksyl, Ostrzeżenia i środki ostrożności)

  • CefaklorcefalosporynaNiewielka

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefaklor, Ostrzeżenia)

  • CefdynircefalosporynaNiewielka

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefdynir, Ostrzeżenia)

  • CefotetancefalosporynaNiewielka

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefotetan, Ostrzeżenia)

  • CefprozylcefalosporynaNiewielka

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Cefprozyl, Ostrzeżenia)

  • CeftazydymcefalosporynaNiewielka

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, IV FLUIDS, IV ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (etykieta leku Ceftazydym, Ostrzeżenia)

  • CeftriaksoncefalosporynaNiewielka

    Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures including oxygen, corticosteroids, intravenous fluids, intravenous antihistamines, pressor amines, and airway management, as clinically indicated. (etykieta leku Ceftriakson, Ostrzeżenia i środki ostrożności)

  • Chinapryl + hydrochlorotiazydinhibitor ACENiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Chininalek przeciwmalarycznyNiewielka

    Drug/Laboratory Interactions Quinine may produce an elevated value for urinary 17-ketogenic steroids when the Zimmerman method is used. (etykieta leku Chinina, Interakcje z innymi lekami)

  • Chlorotiazyddiuretyk tiazydowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Chlortalidondiuretyk tiazydowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • DazatynibNiewielka

    Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etykieta leku Dazatynib, Ostrzeżenia i środki ostrożności)

  • Deksamfetaminalek pobudzający OUNNiewielka

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Deksamfetamina, Interakcje z innymi lekami)

  • Donepezylinhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Droperydolantagonista dopaminyNiewielka

    These would include diuretics, laxatives and supraphysiological use of steroid hormones with mineralocorticoid potential. (etykieta leku Droperydol, Interakcje z innymi lekami)

  • Enalapryl + hydrochlorotiazydinhibitor ACENiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Eplerenonantagonista aldosteronuNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Ewerolimuslek immunosupresyjnyNiewielka

    Corticosteroids may be indicated until clinical symptoms resolve. (etykieta leku Ewerolimus, Ostrzeżenia i środki ostrożności)

  • Fenoksymetylopenicylinaantybiotyk penicylinowyNiewielka

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (etykieta leku Fenoksymetylopenicylina, Ostrzeżenia)

  • Fizostygminainhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • FludarabinaantymetabolitNiewielka

    Steroids may or may not be effective in controlling these hemolytic episodes. (etykieta leku Fludarabina, Ostrzeżenia i środki ostrożności)

  • FluoksetynaSSRINiewielka

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (etykieta leku Fluoksetyna, Ostrzeżenia i środki ostrożności)

  • Fozynopryl + hydrochlorotiazydinhibitor ACENiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Furosemiddiuretyk pętlowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Galantaminainhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • GlukagonNiewielka

    In the reported cases NME resolved with discontinuation of the glucagon, and treatment with corticosteroids was not effective. (etykieta leku Glukagon, Ostrzeżenia i środki ostrożności)

  • Guselkumablek immunosupresyjnyNiewielka

    TREMFYA was subsequently discontinued, and the liver test abnormalities resolved following administration of corticosteroids [see Adverse Reactions (6.1) ] . (etykieta leku Guselkumab, Ostrzeżenia i środki ostrożności)

  • Hydrochlorotiazyddiuretyk tiazydowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Indapamiddiuretyk tiazydowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Ipratropiumlek przeciwcholinergicznyNiewielka

    ATROVENT HFA has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroids commonly used in the treatment of COPD. (etykieta leku Ipratropium, Interakcje z innymi lekami)

  • Irbesartan + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kalcytriolanalog witaminy DNiewielka

    Corticosteroids A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption. (etykieta leku Kalcytriol, Interakcje z innymi lekami)

  • Kandesartan + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Kannabidiol (na receptę)lek przeciwdrgawkowyNiewielka

    Some subjects in the EPIDIOLEX clinical trials had pruritus, erythema, and angioedema requiring treatment, including corticosteroids and antihistamines. (etykieta leku Kannabidiol (na receptę), Ostrzeżenia i środki ostrożności)

  • KlofarabinaantymetabolitNiewielka

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (etykieta leku Klofarabina, Ostrzeżenia i środki ostrożności)

  • Klomifenselektywny modulator receptora estrogenowegoNiewielka

    Elevated urinary steroid levels, varying degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. (etykieta leku Klomifen, Ostrzeżenia)

  • The recovery of the adrenal gland may take from days to months so patients should be protected from the stress (e.g., trauma or surgery) by the use of corticosteroids during the period of stress. (etykieta leku Kortykotropina, Ostrzeżenia i środki ostrożności)

  • Kwas bempedoinowyinhibitor OATP1B1Niewielka

    Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (etykieta leku Kwas bempedoinowy, Ostrzeżenia i środki ostrożności)

  • Kwas etakrynowydiuretyk pętlowyNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • LenalidomidNiewielka

    Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (etykieta leku Lenalidomid, Ostrzeżenia i środki ostrożności)

  • Losartan + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • MelfalanNiewielka

    The infusion should be terminated immediately, followed by the administration of volume expanders, pressor agents, corticosteroids, or antihistamines at the discretion of the physician. (etykieta leku Melfalan, Ostrzeżenia)

  • Memantyna + donepezylinhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Metamfetaminalek pobudzający OUNNiewielka

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (etykieta leku Metamfetamina, Interakcje z innymi lekami)

  • Metoprolol + hydrochlorotiazydbeta-blokerNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Midodrynaagonista receptorów alfa-adrenergicznychNiewielka

    Midodrine hydrochloride has been used in patients concomitantly treated with salt-retaining steroid therapy (i.e., fludrocortisone acetate), with or without salt supplementation. (etykieta leku Midodryna, Interakcje z innymi lekami)

  • MitoksantronNiewielka

    Following concurrent administration of mitoxantrone injection with corticosteroids, no evidence of drug interactions has been observed. (etykieta leku Mitoksantron, Interakcje z innymi lekami)

  • Naltreksonantagonista receptorów opioidowychNiewielka

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (etykieta leku Naltrekson, Ostrzeżenia i środki ostrożności)

  • Neostygminainhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Oksacylinaantybiotyk penicylinowyNiewielka

    If an allergic reaction occurs, the drug should be discontinued and the patient should receive supportive treatment, e.g. , artificial maintenance of ventilation, pressor amines, antihistamines, and corticosteroids. (etykieta leku Oksacylina, Ostrzeżenia)

  • Olanzapina + fluoksetynalek przeciwpsychotycznyNiewielka

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (etykieta leku Olanzapina + fluoksetyna, Ostrzeżenia i środki ostrożności)

  • Olmesartan + amlodypina + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Olmesartan + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Pirydostygminainhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Propylotiouracyllek przeciwtarczycowyNiewielka

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (etykieta leku Propylotiouracyl, Ostrzeżenia)

  • Raloksyfenselektywny modulator receptora estrogenowegoNiewielka

    Other Concomitant Medications EVISTA can be concomitantly administered with ampicillin, amoxicillin, antacids, corticosteroids, and digoxin [see Clinical Pharmacology ( 12.3 )] . (etykieta leku Raloksyfen, Interakcje z innymi lekami)

  • Rytuksymablek immunosupresyjnyNiewielka

    For RA, GPA and MPA, and PV patients, methylprednisolone 100 mg intravenously or its equivalent is recommended 30 minutes prior to each infusion. (etykieta leku Rytuksymab, Ostrzeżenia i środki ostrożności)

  • Rywastygminainhibitor cholinoesterazyNiewielka

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Spironolaktonantagonista aldosteronuNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Spironolakton + hydrochlorotiazydantagonista aldosteronuNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Telmisartan + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • TenekteplazaNiewielka

    If symptoms of hypersensitivity occur, initiate appropriate therapy (e.g., antihistamines, corticosteroids, epinephrine). (etykieta leku Tenekteplaza, Ostrzeżenia i środki ostrożności)

  • Tiamazollek przeciwtarczycowyNiewielka

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (etykieta leku Tiamazol, Ostrzeżenia)

  • TobramycynaaminoglikozydNiewielka

    In clinical studies, patients receiving TOBI Podhaler continued to take dornase alfa, bronchodilators, inhaled corticosteroids, and macrolides. (etykieta leku Tobramycyna, Interakcje z innymi lekami)

  • Triamterendiuretyk oszczędzający potasNiewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Ustekinumablek immunosupresyjnyNiewielka

    Patients improved with discontinuation of therapy and in certain cases administration of corticosteroids. (etykieta leku Ustekinumab, Ostrzeżenia i środki ostrożności)

  • Walsartan + hydrochlorotiazydantagonista receptora angiotensyny II (ARB)Niewielka

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etykieta leku Metyloprednizolon, Interakcje z innymi lekami)

  • Witamina DWitaminy i minerałyNiewielka

    Kortykosteroidy, takie jak prednizon, zmniejszają wchłanianie wapnia i zaburzają metabolizm witaminy D, przyczyniając się do utraty masy kostnej. (NIH Office of Dietary Supplements, Vitamin D)

  • Zyprazydonlek przeciwpsychotycznyNiewielka

    Most patients improved promptly with adjunctive treatment with antihistamines or steroids and/or upon discontinuation of ziprasidone, and all patients experiencing these reactions were reported to recover completely. (etykieta leku Zyprazydon, Ostrzeżenia i środki ostrożności)

Nie zgłoszono istotnej interakcji (1)

  • AminofilinametyloksantynaBrak interakcji

    …dirithromycin enflurane famotidine felodipine finasteride hydrocortisone isoflurane isoniazid isradipine influenza vaccine ketoconazole lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative… (etykieta leku Aminofilina, Interakcje z innymi lekami)

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