Wechselwirkungen von Methylprednisolon

Methylprednisolon (Medrol, Solu-Medrol, Depo-Medrol), ein Kortikosteroid, hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 386 dokumentierte Wechselwirkungen: 30 schwerwiegende, 271 mittelschwere, 84 geringfügige und 1, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.

Wechselwirkungen laut Fachinformation

Schwerwiegende Wechselwirkungen (30)

  • AbirateronCYP2D6-HemmerSchwerwiegend

    Increased fractures and mortality in combination with radium Ra 223 dichloride: Use of YONSA plus methylprednisolone in combination with radium Ra 223 dichloride is not recommended. (Fachinformation zu Abirateron, Warnhinweise und Vorsichtsmaßnahmen)

  • AdalimumabImmunsuppressivumSchwerwiegend

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Adalimumab, Boxed Warning (umrahmter Warnhinweis))

  • AdrenalinSympathomimetikumSchwerwiegend

    …Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline Epinephrine should not be used to counteract circulatory collapse or hypotension caused by phenothiazines, as a reversal of the pressor effects of epinephrine… (Fachinformation zu Adrenalin, Arzneimittelwechselwirkungen)

  • AlkoholAlkoholSchwerwiegend

    DEPO-MEDROL is contraindicated for use in premature infants because the formulation contains benzyl alcohol (see WARNINGS and PRECAUTIONS: Pediatric Use ). (Fachinformation zu Methylprednisolon, Gegenanzeigen)

  • ArformoterolBeta-Adrenozeptor-AgonistSchwerwiegend

    Use of a LABA, including arformoterol tartrate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma. (Fachinformation zu Arformoterol, Gegenanzeigen)

  • ArsentrioxidQT-verlängerndes ArzneimittelSchwerwiegend

    If differentiation syndrome is suspected, immediately initiate high-dose corticosteroids and hemodynamic monitoring until resolution. (Fachinformation zu Arsentrioxid, Boxed Warning (umrahmter Warnhinweis))

  • Atazanavirantiretrovirales ArzneimittelSchwerwiegend

    Coadministration of fluticasone propionate and REYATAZ with ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects [see Warnings and Precautions (5.1) ] . (Fachinformation zu Atazanavir, Arzneimittelwechselwirkungen)

  • AxitinibSchwerwiegend

    Withhold INLYTA and avelumab or pembrolizumab, initiate corticosteroid therapy as needed, and/or permanently discontinue the combination for severe or life-threatening hepatotoxicity. (Fachinformation zu Axitinib, Warnhinweise und Vorsichtsmaßnahmen)

  • BaricitinibJAK-InhibitorSchwerwiegend

    Most patients with rheumatoid arthritis who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Baricitinib, Boxed Warning (umrahmter Warnhinweis))

  • DocetaxelSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Emtricitabin, Rilpivirin und Tenofovirantiretrovirales ArzneimittelSchwerwiegend

    …(5.7) , Drug Interactions (7) , and Clinical Pharmacology (12.3) ]: Anticonvulsants: carbamazepine, oxcarbazepine, phenobarbital, phenytoin Antimycobacterials: rifampin, rifapentine Glucocorticoid (systemic): dexamethasone (more than a single-dose) Herbal Products: St John's wort ( Hypericum perforatum ) Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole,… (Fachinformation zu Emtricitabin, Rilpivirin und Tenofovir, Gegenanzeigen)

  • EtanerceptImmunsuppressivumSchwerwiegend

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Etanercept, Boxed Warning (umrahmter Warnhinweis))

  • FormoterolBeta-Adrenozeptor-AgonistSchwerwiegend

    Use of a LABA, including formoterol fumarate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma [see Warnings and Precautions (5.1) ]. (Fachinformation zu Formoterol, Gegenanzeigen)

  • Fosamprenavirantiretrovirales ArzneimittelSchwerwiegend

    Coadministration of fluticasone and fosamprenavir calcium/ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (Fachinformation zu Fosamprenavir, Arzneimittelwechselwirkungen)

  • InfliximabImmunsuppressivumSchwerwiegend

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Infliximab, Boxed Warning (umrahmter Warnhinweis))

  • KetoconazolAzol-AntimykotikumSchwerwiegend

    Fluticasone: Coadministration of fluticasone propionate and ketoconazole is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (Fachinformation zu Ketoconazol, Arzneimittelwechselwirkungen)

  • LovastatinStatinSchwerwiegend

    Moreover, cholesterol and other products of the cholesterol biosynthesis pathway are essential components for fetal development, including synthesis of steroids and cell membranes. (Fachinformation zu Lovastatin, Gegenanzeigen)

  • MifepristonCYP3A4-HemmerSchwerwiegend

    WARNING: TERMINATION OF PREGNANCY Mifepristone is a potent antagonist of progesterone and cortisol via the progesterone and glucocorticoid (GR-II) receptors, respectively. (Fachinformation zu Mifepriston, Boxed Warning (umrahmter Warnhinweis))

  • MitotanCYP3A4-InduktorSchwerwiegend

    If shock, severe trauma or infection occurs or develops, temporarily discontinue LYSODREN and administer exogenous steroids. (Fachinformation zu Mitotan, Boxed Warning (umrahmter Warnhinweis))

  • MoexiprilACE-HemmerSchwerwiegend

    None of the cases were considered life-threatening and all resolved either without treatment or with medication (antihistamines or glucocorticoids). (Fachinformation zu Moexipril, Warnhinweise)

  • Rilpivirinantiretrovirales ArzneimittelSchwerwiegend

    Antimycobacterials Rifampin Rifapentine Glucocorticoid (systemic) Dexamethasone (more than a single-dose treatment) Herbal Products St. (Fachinformation zu Rilpivirin, Gegenanzeigen)

  • SalmeterolBeta-Adrenozeptor-AgonistSchwerwiegend

    WARNING: ASTHMA-RELATED DEATH Long-acting beta 2 -adrenergic agonists (LABA), such as salmeterol, the active ingredient in SEREVENT DISKUS, as monotherapy (without inhaled corticosteroids [ICS]) increase the risk of asthma-related death. (Fachinformation zu Salmeterol, Boxed Warning (umrahmter Warnhinweis))

  • SirolimusImmunsuppressivumSchwerwiegend

    In a multicenter clinical study, de novo renal transplant patients treated with sirolimus, mycophenolate mofetil (MMF), steroids, and an IL-2 receptor antagonist had significantly higher acute rejection rates and numerically higher death rates compared to patients treated with cyclosporine, MMF, steroids, and IL-2 receptor antagonist. (Fachinformation zu Sirolimus, Warnhinweise und Vorsichtsmaßnahmen)

  • SomatropinSchwerwiegend

    Intervention: Carefully adjust glucocorticoid dosing in pediatric patients receiving glucocorticoid treatments to avoid both hypoadrenalism and an inhibitory effect on growth. (Fachinformation zu Somatropin, Arzneimittelwechselwirkungen)

  • TocilizumabImmunsuppressivumSchwerwiegend

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Tocilizumab, Boxed Warning (umrahmter Warnhinweis))

  • TofacitinibImmunsuppressivumSchwerwiegend

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Tofacitinib, Boxed Warning (umrahmter Warnhinweis))

  • TrandolaprilACE-HemmerSchwerwiegend

    Two of the four cases were life-threatening and resolved without treatment or with medication (corticosteroids). (Fachinformation zu Trandolapril, Warnhinweise)

  • TretinoinRetinoidSchwerwiegend

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (Fachinformation zu Tretinoin, Boxed Warning (umrahmter Warnhinweis))

  • Umeclidiniumbromid und VilanterolAnticholinergikumSchwerwiegend

    • use of a long-acting beta 2 -adrenergic agonist (LABA), including vilanterol, one of the active ingredients in Umeclidinium and Vilanterol ELLIPTA, without an inhaled corticosteroid (ICS), in patients with asthma [see Warnings and Precautions ( 5.1 )] . (Fachinformation zu Umeclidiniumbromid und Vilanterol, Gegenanzeigen)

  • UpadacitinibImmunsuppressivumSchwerwiegend

    Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. (Fachinformation zu Upadacitinib, Boxed Warning (umrahmter Warnhinweis))

Mittelschwere Wechselwirkungen (271)

  • AcarboseAntidiabetikumMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AcetylsalicylsäureNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Acetylsalicylsäure und DipyridamolThrombozytenaggregationshemmerMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AclidiniumbromidAnticholinergikumMittelschwer

    Sympathomimetics, Methylxanthines, Steroids In clinical studies, concurrent administration of aclidinium bromide and other drugs commonly used in the treatment of COPD including sympathomimetics (short-acting beta 2 agonists), methylxanthines, and oral and inhaled steroids showed no increases in adverse drug reactions. (Fachinformation zu Aclidiniumbromid, Arzneimittelwechselwirkungen)

  • AfatinibMittelschwer

    Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (Fachinformation zu Afatinib, Warnhinweise und Vorsichtsmaßnahmen)

  • AlbendazolMittelschwer

    Risk of Neurologic Symptoms: Neurocysticercosis patients may experience cerebral hypertensive episodes, seizures or focal neurologic deficits after initiation of therapy; begin appropriate steroid and anticonvulsant therapy. (Fachinformation zu Albendazol, Warnhinweise und Vorsichtsmaßnahmen)

  • AlemtuzumabImmunsuppressivumMittelschwer

    Institute appropriate medical management (e.g., glucocorticoids, epinephrine, meperidine) for infusion-related reactions as needed [see Dosage and Administration (2.2) ] . (Fachinformation zu Alemtuzumab, Warnhinweise und Vorsichtsmaßnahmen)

  • AlendronsäureBisphosphonatMittelschwer

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (Fachinformation zu Alendronsäure, Warnhinweise und Vorsichtsmaßnahmen)

  • AliskirenAntihypertensivumMittelschwer

    Patients who experience these effects, even without respiratory distress, require prolonged observation and appropriate monitoring measures since treatment with antihistamines and corticosteroids may not be sufficient to prevent respiratory involvement. (Fachinformation zu Aliskiren, Warnhinweise und Vorsichtsmaßnahmen)

  • AlogliptinDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Alogliptin und MetforminDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AlpelisibMittelschwer

    If a SCAR is not confirmed, VIJOICE may require dose modifications, topical or systemic corticosteroids, or oral antihistamine treatment as described in Table 4 [see Dosage and Administration (2.5)] . (Fachinformation zu Alpelisib, Warnhinweise und Vorsichtsmaßnahmen)

  • Amphotericin BAntimykotikumMittelschwer

    There have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure (see CONTRAINDICATIONS and PRECAUTIONS: Drug Interactions, Amphotericin B injection and potassium-depleting agents ). (Fachinformation zu Methylprednisolon, Warnhinweise)

  • ApixabanAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AprepitantCYP3A4-HemmerMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ArgatrobanAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ArmodafinilZNS-StimulansMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AzithromycinMakrolid-AntibiotikumMittelschwer

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BalsalazidSalicylatMittelschwer

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BeclometasonKortikosteroidMittelschwer

    Lung function (FEV 1 or PEF), beta‑agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral or other systemic corticosteroids. (Fachinformation zu Beclometason, Warnhinweise und Vorsichtsmaßnahmen)

  • Belladonna und OpiumOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Belladonna und Opium, Warnhinweise und Vorsichtsmaßnahmen)

  • BendamustinMittelschwer

    Consider measures to prevent severe reactions, including antihistamines, antipyretics and corticosteroids in subsequent cycles in patients who have experienced Grade 1 or 2 infusion reactions. (Fachinformation zu Bendamustin, Warnhinweise und Vorsichtsmaßnahmen)

  • BenralizumabMittelschwer

    • Reduction in Corticosteroid Dosage: Do not discontinue systemic or inhaled corticosteroids abruptly upon initiation of therapy with FASENRA. (Fachinformation zu Benralizumab, Warnhinweise und Vorsichtsmaßnahmen)

  • BexagliflozinSGLT-2-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Bictegravir, Emtricitabin und Tenofoviralafenamidantiretrovirales ArzneimittelMittelschwer

    Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) ↓ lenacapavir (dexamethasone) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (Fachinformation zu Bictegravir, Emtricitabin und Tenofoviralafenamid, Arzneimittelwechselwirkungen)

  • BismutsubsalicylatSalicylatMittelschwer

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BivalirudinAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BosentanCYP3A4-InduktorMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Budesonid und FormoterolKortikosteroidMittelschwer

    In this situation, the patient requires immediate re-evaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of budesonide and formoterol fumarate dihydrate with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (Fachinformation zu Budesonid und Formoterol, Warnhinweise und Vorsichtsmaßnahmen)

  • BuprenorphinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Buprenorphin, Warnhinweise und Vorsichtsmaßnahmen)

  • Buprenorphin und NaloxonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Buprenorphin und Naloxon, Warnhinweise und Vorsichtsmaßnahmen)

  • BupropionAntidepressivumMittelschwer

    …risk of seizure: concomitant use of other medications that lower the seizure threshold (e.g., other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, and systemic corticosteroids), metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia), or use of illicit drugs (e.g., cocaine) or abuse or misuse… (Fachinformation zu Bupropion, Warnhinweise und Vorsichtsmaßnahmen)

  • Butalbital und ParacetamolBarbituratMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ButorphanolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Butorphanol, Warnhinweise)

  • CanagliflozinSGLT-2-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CarbamazepinAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CefoxitinCephalosporinMittelschwer

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Fachinformation zu Cefoxitin, Warnhinweise und Vorsichtsmaßnahmen)

  • CelecoxibNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CenobamatAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CiclosporinImmunsuppressivumMittelschwer

    Cyclosporine : Increased activity of both cyclosporine and corticosteroids may occur when the two are used concurrently. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CiprofloxacinFluorchinolonMittelschwer

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Fachinformation zu Ciprofloxacin, Warnhinweise und Vorsichtsmaßnahmen)

  • CladribinAntimetabolitMittelschwer

    Prevention or Management Consider a possible decrease in cladribine efficacy if potent BCRP (e.g., corticosteroids) or P-gp (e.g., rifampicin, St. (Fachinformation zu Cladribin, Arzneimittelwechselwirkungen)

  • ClarithromycinMakrolid-AntibiotikumMittelschwer

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ClobazamBenzodiazepinMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CodeinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Codein, Warnhinweise und Vorsichtsmaßnahmen)

  • ColestyraminGallensäurebinderMittelschwer

    Cholestyramine : Cholestyramine may increase the clearance of oral corticosteroids. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • CytarabinAntimetabolitMittelschwer

    These reactions include reversible corneal toxicity, and hemorrhagic conjunctivitis, which may be prevented or diminished by prophylaxis with a local corticosteroid eye drop; cerebral and cerebellar dysfunction, including personality changes, somnolence and coma, usually reversible; severe gastrointestinal ulceration, including pneumatosis cystoides intestinalis… (Fachinformation zu Cytarabin, Warnhinweise)

  • DabigatranAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DapagliflozinSGLT-2-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Dapagliflozin und MetforminSGLT-2-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DaptomycinAntibiotikumMittelschwer

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Fachinformation zu Daptomycin, Warnhinweise und Vorsichtsmaßnahmen)

  • Darunavirantiretrovirales ArzneimittelMittelschwer

    Corticosteroids primarily metabolized by CYP3A: e.g. betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone ↑ corticosteroids Co-administration with corticosteroids (all routes of administration) of which exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal… (Fachinformation zu Darunavir, Arzneimittelwechselwirkungen)

  • Darunavir und Cobicistatantiretrovirales ArzneimittelMittelschwer

    Corticosteroids: dexamethasone (systemic) Corticosteroids primarily metabolized by CYP3A: e.g. betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone ↓ darunavir ↓ cobicistat ↑ corticosteroids Co-administration with systemic dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic… (Fachinformation zu Darunavir und Cobicistat, Arzneimittelwechselwirkungen)

  • DeferasiroxEisenpräparatMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DenosumabMittelschwer

    Other risk factors for the development of ONJ include immunosuppressive therapy, treatment with angiogenesis inhibitors, systemic corticosteroids, diabetes, and gingival infections. (Fachinformation zu Denosumab, Warnhinweise und Vorsichtsmaßnahmen)

  • Desogestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DexamethasonKortikosteroidMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DiclofenacNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DicycloverinAnticholinergikumMittelschwer

    Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corticosteroids. (Fachinformation zu Dicycloverin, Arzneimittelwechselwirkungen)

  • DiflunisalNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DigoxinDigitalisglykosidMittelschwer

    Digitalis glycosides : Patients on digitalis glycosides may be at increased risk of arrhythmias due to hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Drospirenon und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DulaglutidGLP-1-RezeptoragonistMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DupilumabMittelschwer

    Eosinophilic Conditions: Be alert to vasculitic rash, worsening pulmonary symptoms, cardiac complications, kidney injury and/or neuropathy, especially upon reduction of oral corticosteroids. (Fachinformation zu Dupilumab, Warnhinweise und Vorsichtsmaßnahmen)

  • EdoxabanAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Efavirenzantiretrovirales ArzneimittelMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Efavirenz, Lamivudin und Tenofovirantiretrovirales ArzneimittelMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Although other risk factors were present in some cases (such as corticosteroid use, exposure to radiation), a possible risk attributable to treatment with ivacaftor cannot be excluded. (Fachinformation zu Elexacaftor, Tezacaftor und Ivacaftor, Warnhinweise und Vorsichtsmaßnahmen)

  • Elvitegravir, Cobicistat, Emtricitabin und Tenofovirantiretrovirales ArzneimittelMittelschwer

    Corticosteroids: e.g., betamethasone budesonide ciclesonide dexamethasone fluticasone methylprednisolone mometasone prednisone triamcinolone ↓ elvitegravir ↓ cobicistat ↑ corticosteroids Coadministration with oral dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic effect and development of resistance to elvitegravir. (Fachinformation zu Elvitegravir, Cobicistat, Emtricitabin und Tenofovir, Arzneimittelwechselwirkungen)

  • EmpagliflozinSGLT-2-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Empagliflozin und MetforminSGLT-2-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EnoxaparinAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ErlotinibMittelschwer

    Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (Fachinformation zu Erlotinib, Warnhinweise und Vorsichtsmaßnahmen)

  • ErythromycinMakrolid-AntibiotikumMittelschwer

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EslicarbazepinAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EstradiolEstrogenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Estradiol und Dienogestorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Estradiol und NorethisteronEstrogenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EtodolacNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Etravirinantiretrovirales ArzneimittelMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Etynodioldiacetat und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ExenatidGLP-1-RezeptoragonistMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • FenoprofenNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • FentanylOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Fentanyl, Warnhinweise und Vorsichtsmaßnahmen)

  • FidaxomicinMakrolid-AntibiotikumMittelschwer

    Antibiotics : Macrolide antibiotics have been reported to cause a significant decrease in corticosteroid clearance (see PRECAUTIONS: Drug Interactions, Hepatic Enzyme Inhibitors ). (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • FingolimodImmunsuppressivumMittelschwer

    In both cases, the patients were taking a 1.25 mg dose of fingolimod (higher than the recommended 0.5 mg dose) and had received high-dose corticosteroid therapy to treat suspected MS relapses. (Fachinformation zu Fingolimod, Warnhinweise und Vorsichtsmaßnahmen)

  • FlunisolidKortikosteroidMittelschwer

    Pregnancy As with other corticosteroids, flunisolide has been shown to be teratogenic and fetotoxic in rabbits and rats at oral doses of 40 and 200 mcg/kg/day, respectively (approximately 2 and 4 times, respectively, the maximum recommended daily intranasal dose in adults on a mg/m 2 basis). (Fachinformation zu Flunisolid, Vorsichtsmaßnahmen)

  • FluocinonidKortikosteroidMittelschwer

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic absorption of topical corticosteroids. (Fachinformation zu Fluocinonid, Warnhinweise und Vorsichtsmaßnahmen)

  • FlurbiprofenNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Fluticason und SalmeterolKortikosteroidMittelschwer

    In this situation, the patient requires immediate reevaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of Fluticasone Propionate/Salmeterol MDPI with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (Fachinformation zu Fluticason und Salmeterol, Warnhinweise und Vorsichtsmaßnahmen)

  • FondaparinuxAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • FosaprepitantCYP3A4-HemmerMittelschwer

    Methylprednisolone Clinical Impact Increased methylprednisolone exposure [see Clinical Pharmacology ( 12.3 )]. (Fachinformation zu Fosaprepitant, Arzneimittelwechselwirkungen)

  • FosphenytoinAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • FulvestrantEstrogenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • GlibenclamidSulfonylharnstoffMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Glibenclamid und MetforminSulfonylharnstoffMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • GlimepiridSulfonylharnstoffMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • GlipizidSulfonylharnstoffMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Glipizid und MetforminSulfonylharnstoffMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Corticosteroids, valproic acid, or haloperidol : May increase plasma ammonia level; monitor ammonia levels closely. (Fachinformation zu Glycerolphenylbutyrat, Arzneimittelwechselwirkungen)

  • GriseofulvinAntimykotikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • HalobetasolKortikosteroidMittelschwer

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic exposure to topical corticosteroids. (Fachinformation zu Halobetasol, Warnhinweise und Vorsichtsmaßnahmen)

  • HaloperidolAntipsychotikumMittelschwer

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (Fachinformation zu Haloperidol, Arzneimittelwechselwirkungen)

  • HeparinAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Humaninsulin (Normalinsulin)InsulinMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • HydralazinVasodilatatorMittelschwer

    Long-term treatment with steroids may be necessary (see PRECAUTIONS, Laboratory Tests ). (Fachinformation zu Hydralazin, Warnhinweise)

  • HydrocodonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Hydrocodon, Warnhinweise und Vorsichtsmaßnahmen)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Hydrocodon und Chlorphenamin, Warnhinweise und Vorsichtsmaßnahmen)

  • Hydrocodon und HomatropinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Hydrocodon und Homatropin, Warnhinweise und Vorsichtsmaßnahmen)

  • Hydrocodon und IbuprofenOpioidMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Hydrocodon und ParacetamolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Hydrocodon und Paracetamol, Warnhinweise)

  • HydrocortisonKortikosteroidMittelschwer

    There have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure (see CONTRAINDICATIONS and PRECAUTIONS: Drug Interactions, Amphotericin B injection and potassium-depleting agents ). (Fachinformation zu Methylprednisolon, Warnhinweise)

  • HydromorphonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Hydromorphon, Warnhinweise und Vorsichtsmaßnahmen)

  • IbandronsäureBisphosphonatMittelschwer

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (Fachinformation zu Ibandronsäure, Warnhinweise und Vorsichtsmaßnahmen)

  • IbuprofenNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Ibuprofen und FamotidinNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ImatinibCYP3A4-HemmerMittelschwer

    If either is abnormal, consider prophylactic use of systemic steroids (1-2 mg/kg) for one to two weeks concomitantly with Gleevec at the initiation of therapy. (Fachinformation zu Imatinib, Warnhinweise und Vorsichtsmaßnahmen)

  • IndometacinNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Insulin aspartInsulinMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Insulin degludecInsulinMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Insulin detemirInsulinMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Insulin glarginInsulinMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Insulin lisproInsulinMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • IsoniazidAntibiotikumMittelschwer

    Antitubercular drugs : Serum concentrations of isoniazid may be decreased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ItraconazolAzol-AntimykotikumMittelschwer

    Budesonide (inhalation) Budesonide (noninhalation) Ciclesonide (inhalation) Cyclosporine (IV) Cyclosporine (non-IV) Dexamethasone Fluticasone (inhalation) Fluticasone (nasal) Methylprednisolone Tacrolimus (IV) Tacrolimus (oral) Monitor for adverse reactions. (Fachinformation zu Itraconazol, Arzneimittelwechselwirkungen)

  • IvacaftorCYP3A4-HemmerMittelschwer

    Although other risk factors were present in some cases (such as corticosteroid use and/or exposure to radiation), a possible risk attributable to KALYDECO cannot be excluded. (Fachinformation zu Ivacaftor, Warnhinweise und Vorsichtsmaßnahmen)

  • IvermectinMittelschwer

    Oral hydration, recumbency, intravenous normal saline, and/or parenteral corticosteroids have been used to treat postural hypotension. (Fachinformation zu Ivermectin, Warnhinweise)

  • KetoprofenNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • KetorolacNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • KokainLokalanästhetikumMittelschwer

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (Fachinformation zu Kokain, Arzneimittelwechselwirkungen)

  • Konjugierte EstrogeneEstrogenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Lenacapavirantiretrovirales ArzneimittelMittelschwer

    Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (Fachinformation zu Lenacapavir, Arzneimittelwechselwirkungen)

  • LevofloxacinFluorchinolonMittelschwer

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients usually over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Fachinformation zu Levofloxacin, Warnhinweise und Vorsichtsmaßnahmen)

  • LevonorgestrelGestagenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Levonorgestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • LevorphanolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Levorphanol, Warnhinweise)

  • LevosalbutamolBeta-Adrenozeptor-AgonistMittelschwer

    If the patient needs more doses of XOPENEX HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (Fachinformation zu Levosalbutamol, Warnhinweise und Vorsichtsmaßnahmen)

  • LevothyroxinSchilddrüsenhormonMittelschwer

    Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (Fachinformation zu Levothyroxin, Warnhinweise und Vorsichtsmaßnahmen)

  • Levothyroxin und LiothyroninSchilddrüsenhormonMittelschwer

    The therapy of myxedema coma requires simultaneous administration of glucocorticoids (See DOSAGE AND ADMINISTRATION). (Fachinformation zu Levothyroxin und Liothyronin, Vorsichtsmaßnahmen)

  • LinagliptinDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Linagliptin und MetforminDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • LiothyroninSchilddrüsenhormonMittelschwer

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (Fachinformation zu Liothyronin, Warnhinweise und Vorsichtsmaßnahmen)

  • LiraglutidGLP-1-RezeptoragonistMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Lisinopril und HydrochlorothiazidACE-HemmerMittelschwer

    Even in those instances where swelling of only the tongue is involved, without respiratory distress, patients may require prolonged observation since treatment with antihistamines and corticosteroids may not be sufficient. (Fachinformation zu Lisinopril und Hydrochlorothiazid, Warnhinweise)

  • Lopinavir und Ritonavirantiretrovirales ArzneimittelMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • LorlatinibCYP3A4-InduktorMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MargetuximabMittelschwer

    In patients who experience mild or moderate IRRs, consider premedications, including antihistamines, corticosteroids, and antipyretics. (Fachinformation zu Margetuximab, Warnhinweise und Vorsichtsmaßnahmen)

  • MedroxyprogesteronGestagenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MefenaminsäureNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MegestrolGestagenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MeloxicamNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Menthol und MethylsalicylatSalicylatMittelschwer

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MepolizumabMittelschwer

    Decrease corticosteroids gradually, if appropriate. (Fachinformation zu Mepolizumab, Warnhinweise und Vorsichtsmaßnahmen)

  • MesalazinSalicylatMittelschwer

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MetforminBiguanidMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MethadonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Methadon, Warnhinweise und Vorsichtsmaßnahmen)

  • MethazolamidCarboanhydrasehemmerMittelschwer

    Drug Interactions Methazolamide should be used with caution in patients on steroid therapy because of the potential for developing hypokalemia. (Fachinformation zu Methazolamid, Arzneimittelwechselwirkungen)

  • MethohexitalBarbituratMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MethotrexatImmunsuppressivumMittelschwer

    NSAIDs, Aspirin, and Steroids: May elevate and prolong serum methotrexate levels and increase gastrointestinal toxicity. (Fachinformation zu Methotrexat, Arzneimittelwechselwirkungen)

  • MethyldopaAntihypertensivumMittelschwer

    If not, corticosteroids may be given and other causes of anemia should be considered. (Fachinformation zu Methyldopa, Warnhinweise)

  • MethyltestosteronAndrogenMittelschwer

    Testosterone has been subject to abuse, typically at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids. (Fachinformation zu Methyltestosteron, Warnhinweise)

  • MetolazonThiaziddiuretikumMittelschwer

    Corticosteroids Or ACTH May increase the risk of hypokalemia and increase salt and water retention. (Fachinformation zu Metolazon, Arzneimittelwechselwirkungen)

  • MetyraponMittelschwer

    This can be corrected by giving appropriate doses of corticosteroids. (Fachinformation zu Metyrapon, Warnhinweise und Vorsichtsmaßnahmen)

  • MiglitolAntidiabetikumMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MitapivatCYP3A4-InduktorMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ModafinilZNS-StimulansMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MometasonKortikosteroidMittelschwer

    Lung function (FEV 1 or PEF), beta-agonist use, and asthma symptoms should be carefully monitored during withdrawal of oral or other systemic corticosteroids. (Fachinformation zu Mometason, Warnhinweise und Vorsichtsmaßnahmen)

  • MontelukastLeukotrienrezeptor-AntagonistMittelschwer

    Inhaled corticosteroid may be reduced gradually. (Fachinformation zu Montelukast, Warnhinweise und Vorsichtsmaßnahmen)

  • MorphinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Morphin, Warnhinweise und Vorsichtsmaßnahmen)

  • MoxifloxacinFluorchinolonMittelschwer

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Fachinformation zu Moxifloxacin, Warnhinweise und Vorsichtsmaßnahmen)

  • NabumetonNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • NafcillinPenicillin-AntibiotikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • NalbuphinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Nalbuphin, Warnhinweise)

  • Naltrexon und BupropionOpioidantagonistMittelschwer

    …hypoglycemia concomitant administration of medications that may lower the seizure threshold, including other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, systemic steroids Recommendations for Reducing the Risk of Seizure: Clinical experience with bupropion suggests that the risk of seizure may be minimized by adhering to the recommended… (Fachinformation zu Naltrexon und Bupropion, Warnhinweise und Vorsichtsmaßnahmen)

  • NaproxenNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Naproxen und EsomeprazolNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • NatalizumabImmunsuppressivumMittelschwer

    In Studies MS1 and MS2, an increase in infections was seen in patients concurrently receiving short courses of corticosteroids. (Fachinformation zu Natalizumab, Warnhinweise und Vorsichtsmaßnahmen)

  • NateglinidGlinidMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Use of corticosteroids may cause a protein catabolic state and, thereby, potentially increase plasma ammonia levels in patients with impaired ability to form urea. (Fachinformation zu Natriumphenylacetat und Natriumbenzoat, Arzneimittelwechselwirkungen)

  • Valproic Acid, Haloperidol, or Corticosteroids : May increase plasma ammonia level; monitor ammonia levels closely. (Fachinformation zu Natriumphenylbutyrat, Arzneimittelwechselwirkungen)

  • Nevirapinantiretrovirales ArzneimittelMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • NintedanibMittelschwer

    Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (Fachinformation zu Nintedanib, Warnhinweise und Vorsichtsmaßnahmen)

  • Nirmatrelvir und RitonavirVirostatikumMittelschwer

    Corticosteroids primarily metabolized by CYP3A betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, triamcinolone ↑ corticosteroid Co-administration with corticosteroids (all routes of administration) of which exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing’s syndrome… (Fachinformation zu Nirmatrelvir und Ritonavir, Arzneimittelwechselwirkungen)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • NorethisteronGestagenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Norethisteron und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Norgestimat und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Norgestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • OcrelizumabImmunsuppressivumMittelschwer

    In multiple sclerosis (MS) clinical trials, all adult and pediatric patients who were treated with OCREVUS received premedication with methylprednisolone (or an equivalent steroid), and may have also received an antihistamine (all pediatric patients) and/or an analgesic/antipyretic to reduce the risk of infusion reactions prior to each infusion. (Fachinformation zu Ocrelizumab, Warnhinweise und Vorsichtsmaßnahmen)

  • OfloxacinFluorchinolonMittelschwer

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Fachinformation zu Ofloxacin, Warnhinweise)

  • OliceridinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Oliceridin, Warnhinweise und Vorsichtsmaßnahmen)

  • OmalizumabMittelschwer

    Corticosteroid Reduction: Do not abruptly discontinue corticosteroids upon initiation of OMLYCLO therapy. (Fachinformation zu Omalizumab, Warnhinweise und Vorsichtsmaßnahmen)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • OxaprozinNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • OxcarbazepinAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • OxycodonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Oxycodon, Warnhinweise und Vorsichtsmaßnahmen)

  • Oxycodon und ParacetamolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Oxycodon und Paracetamol, Warnhinweise und Vorsichtsmaßnahmen)

  • OxymorphonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Oxymorphon, Warnhinweise und Vorsichtsmaßnahmen)

  • PamidronsäureBisphosphonatMittelschwer

    Many of these patients were also receiving chemotherapy and corticosteroids, which may be risk factors for ONJ. (Fachinformation zu Pamidronsäure, Warnhinweise und Vorsichtsmaßnahmen)

  • Paracetamol und CodeinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Paracetamol und Codein, Warnhinweise)

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • PasireotidMittelschwer

    If adrenal insufficiency is suspected, it should be confirmed and treated per standard of care with exogenous glucocorticoids at replacement doses . (Fachinformation zu Pasireotid, Warnhinweise und Vorsichtsmaßnahmen)

  • PenicillaminMittelschwer

    Treatment has consisted of high doses of corticosteroids alone or, in some cases, concomitantly with an immunosuppressant. (Fachinformation zu Penicillamin, Warnhinweise)

  • Pentazocin und NaloxonOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Pentazocin und Naloxon, Warnhinweise)

  • PethidinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Pethidin, Warnhinweise und Vorsichtsmaßnahmen)

  • PhenobarbitalBarbituratMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Phentermin und TopiramatZNS-StimulansMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Phenylephrinabschwellendes Mittel (Dekongestivum)Mittelschwer

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (Fachinformation zu Phenylephrin, Arzneimittelwechselwirkungen)

  • PhenytoinAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • PioglitazonThiazolidindion (Glitazon)Mittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Pioglitazon und GlimepiridThiazolidindion (Glitazon)Mittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Pioglitazon und MetforminThiazolidindion (Glitazon)Mittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • PiroxicamNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • PonesimodImmunsuppressivumMittelschwer

    Prior and Concomitant Treatment with Anti-neoplastic, Immune-Modulating, or Immunosuppressive Therapies Anti-neoplastic, immune-modulating, or immunosuppressive therapies (including corticosteroids) should be coadministered with caution because of the risk of additive immune system effects [see Drug Interactions (7.1) ] . (Fachinformation zu Ponesimod, Warnhinweise und Vorsichtsmaßnahmen)

  • PrimidonAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ProgesteronGestagenMittelschwer

    Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Promethazin und CodeinOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Promethazin und Codein, Warnhinweise und Vorsichtsmaßnahmen)

  • PropofolZNS-dämpfendes ArzneimittelMittelschwer

    The following appear to be major risk factors for the development of these events: decreased oxygen delivery to tissues; serious neurological injury and/or sepsis; high dosages of one or more of the following pharmacological agents: vasoconstrictors, steroids, inotropes and/or prolonged, high-dose infusions of propofol (> 5 mg/kg/hour for > 48 hours). (Fachinformation zu Propofol, Warnhinweise und Vorsichtsmaßnahmen)

  • RepaglinidGlinidMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • RifabutinAntibiotikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • RifampicinAntibiotikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • RifapentinAntibiotikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • RisedronsäureBisphosphonatMittelschwer

    …the jaw include invasive dental procedures (for example, tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (for example, chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (for example, periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection,… (Fachinformation zu Risedronsäure, Warnhinweise und Vorsichtsmaßnahmen)

  • Ritonavirantiretrovirales ArzneimittelMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • RivaroxabanAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Rocuroniumneuromuskulärer BlockerMittelschwer

    Therefore, for patients receiving both neuromuscular blocking agents (including Rocuronium Bromide Injection) and corticosteroids, the period of use of the neuromuscular blocking agent should be limited as much as possible and only used in the setting where in the opinion of the prescribing physician, the specific advantages of the drug outweigh the risk. (Fachinformation zu Rocuronium, Warnhinweise und Vorsichtsmaßnahmen)

  • SalbutamolBeta-Adrenozeptor-AgonistMittelschwer

    If the patient needs more doses of Albuterol Sulfate HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (Fachinformation zu Salbutamol, Warnhinweise und Vorsichtsmaßnahmen)

  • SalsalatNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • SaxagliptinDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Saxagliptin und MetforminDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • SemaglutidGLP-1-RezeptoragonistMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • SitagliptinDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Sitagliptin und MetforminDPP-4-HemmerMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • SulfasalazinSulfonamidMittelschwer

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • SulindacNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Sumatriptan und NaproxenTriptanMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Suxamethoniumneuromuskulärer BlockerMittelschwer

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (Fachinformation zu Suxamethonium, Arzneimittelwechselwirkungen)

  • SuzetriginCYP3A4-InduktorMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • TacrolimusImmunsuppressivumMittelschwer

    Mild or Moderate CYP3A Inducers Methylprednisolone, prednisone May decrease tacrolimus whole blood trough concentrations. (Fachinformation zu Tacrolimus, Arzneimittelwechselwirkungen)

  • TapentadolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Tapentadol, Warnhinweise und Vorsichtsmaßnahmen)

  • TemozolomidMittelschwer

    Pneumocystis Pneumonia (PCP) : Closely monitor all patients, particularly those receiving steroids, for the development of lymphopenia and PCP. (Fachinformation zu Temozolomid, Warnhinweise und Vorsichtsmaßnahmen)

  • TemsirolimusMittelschwer

    If ILD is suspected, discontinue TORISEL, and consider use of corticosteroids and/or antibiotics. (Fachinformation zu Temsirolimus, Warnhinweise und Vorsichtsmaßnahmen)

  • TerbutalinBeta-Adrenozeptor-AgonistMittelschwer

    If the patient needs more doses of terbutaline sulfate tablets than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and the treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (Fachinformation zu Terbutalin, Warnhinweise)

  • TeriparatidSchilddrüsenhormonMittelschwer

    Risk factors for development of calciphylaxis include underlying auto-immune disease, kidney failure, and concomitant warfarin or systemic corticosteroid use. (Fachinformation zu Teriparatid, Warnhinweise und Vorsichtsmaßnahmen)

  • TesamorelinMittelschwer

    Glucocorticoids : Patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA SV. (Fachinformation zu Tesamorelin, Arzneimittelwechselwirkungen)

  • TestosteronAndrogenMittelschwer

    Abuse of Testosterone and Monitoring of Serum Testosterone : If testosterone use at doses higher than recommended for the approved indication and in combination with other anabolic androgenic steroids is suspected, check serum testosterone concentration ( 5.5 ). (Fachinformation zu Testosteron, Warnhinweise und Vorsichtsmaßnahmen)

  • TheophyllinMethylxanthinMittelschwer

    Dosage Increases: Increases in the dose of theophylline should not be made in response to an acute exacerbation of symptoms of chronic lung disease since theophylline provides little added benefit to inhaled beta2 -selective agonists and systemically administered corticosteroids in this circumstance and increases the risk of adverse effects. (Fachinformation zu Theophyllin, Warnhinweise)

  • TiotropiumbromidAnticholinergikumMittelschwer

    Concomitant Respiratory Medications SPIRIVA RESPIMAT has been used concomitantly with short-acting and long-acting sympathomimetic (beta-agonists) bronchodilators, methylxanthines, oral and inhaled steroids, antihistamines, mucolytics, leukotriene modifiers, cromones, and anti-IgE treatment without increases in adverse reactions. (Fachinformation zu Tiotropiumbromid, Arzneimittelwechselwirkungen)

  • TirzepatidGLP-1-RezeptoragonistMittelschwer

    Antidiabetics : Because corticosteroids may increase blood glucose concentrations, dosage adjustments of antidiabetic agents may be required. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • TolmetinNSARMittelschwer

    Nonsteroidal anti-inflammatory drugs (NSAIDs) : Concomitant use of aspirin (or other nonsteroidal anti-inflammatory agents) and corticosteroids increases the risk of gastrointestinal side effects. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • TopiramatAntiepileptikumMittelschwer

    Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin) : Drugs which induce cytochrome P450 3A4 enzyme activity may enhance the metabolism of corticosteroids and require that the dosage of the corticosteroid be increased. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • TorasemidSchleifendiuretikumMittelschwer

    Corticosteroids and ACTH: Increased risk of hypokalemia. (Fachinformation zu Torasemid, Arzneimittelwechselwirkungen)

  • TramadolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Tramadol, Warnhinweise und Vorsichtsmaßnahmen)

  • Tramadol und ParacetamolOpioidMittelschwer

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fachinformation zu Tramadol und Paracetamol, Warnhinweise und Vorsichtsmaßnahmen)

  • TrastuzumabMittelschwer

    Interrupt TRAZIMERA infusion in all patients experiencing dyspnea, clinically significant hypotension, and intervention of medical therapy administered (which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators, and oxygen). (Fachinformation zu Trastuzumab, Warnhinweise und Vorsichtsmaßnahmen)

  • TriamcinolonKortikosteroidMittelschwer

    Results from one multicenter, randomized, placebo-controlled study with methylprednisolone hemisuccinate, an intravenous corticosteroid, showed an increase in early (at 2 weeks) and late (at 6 months) mortality in patients with cranial trauma who were determined not to have other clear indications for corticosteroid treatment. (Fachinformation zu Triamcinolon, Warnhinweise)

  • Triamteren und Hydrochlorothiazidkaliumsparendes DiuretikumMittelschwer

    Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (Fachinformation zu Triamteren und Hydrochlorothiazid, Arzneimittelwechselwirkungen)

  • ValproinsäureAntiepileptikumMittelschwer

    Oral Contraceptive Steroids Administration of a single-dose of ethinyloestradiol (50 mcg)/levonorgestrel (250 mcg) to 6 women on valproate (200 mg BID) therapy for 2 months did not reveal any pharmacokinetic interaction. (Fachinformation zu Valproinsäure, Arzneimittelwechselwirkungen)

  • Estrogens, including oral contraceptives : Estrogens may decrease the hepatic metabolism of certain corticosteroids, thereby increasing their effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • VoriconazolAzol-AntimykotikumMittelschwer

    • Adrenal Dysfunction : Carefully monitor patients receiving voriconazole and corticosteroids (via all routes of administration) for adrenal dysfunction both during and after voriconazole treatment. (Fachinformation zu Voriconazol, Warnhinweise und Vorsichtsmaßnahmen)

  • WarfarinAntikoagulans (Gerinnungshemmer)Mittelschwer

    Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ZenocutuzumabMittelschwer

    Prior to the first BIZENGRI infusion, premedicate with a corticosteroid, an H1 antihistamine and acetaminophen to reduce the risk of IRRs [see Dosage and Administration (2.4) ]. (Fachinformation zu Zenocutuzumab, Warnhinweise und Vorsichtsmaßnahmen)

  • ZoledronsäureBisphosphonatMittelschwer

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (Fachinformation zu Zoledronsäure, Warnhinweise und Vorsichtsmaßnahmen)

Geringfügige Erwähnungen (84)

  • AcetazolamidCarboanhydrasehemmerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AlteplaseGeringfügig

    If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy (e.g., antihistamines, intravenous corticosteroids, epinephrine). (Fachinformation zu Alteplase, Warnhinweise und Vorsichtsmaßnahmen)

  • AmfetaminZNS-StimulansGeringfügig

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Fachinformation zu Amfetamin, Arzneimittelwechselwirkungen)

  • Amfetamin und DexamfetaminZNS-StimulansGeringfügig

    Interference with Laboratory Tests Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Fachinformation zu Amfetamin und Dexamfetamin, Arzneimittelwechselwirkungen)

  • AmikacinAminoglykosidGeringfügig

    Most patients with hypersensitivity pneumonitis discontinued treatment with ARIKAYCE and received treatment with corticosteroids [see Adverse Reactions (6.1) ] . (Fachinformation zu Amikacin, Warnhinweise und Vorsichtsmaßnahmen)

  • Amiloridkaliumsparendes DiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • AmiodaronAntiarrhythmikumGeringfügig

    Antithyroid drugs, β-adrenergic blockers, temporary corticosteroid therapy may be necessary to treat the symptoms of hyperthyroidism. (Fachinformation zu Amiodaron, Warnhinweise und Vorsichtsmaßnahmen)

  • AmpicillinPenicillin-AntibiotikumGeringfügig

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (Fachinformation zu Ampicillin, Warnhinweise)

  • Atenolol und ChlortalidonBetablockerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BempedoinsäureOATP1B1-HemmerGeringfügig

    Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (Fachinformation zu Bempedoinsäure, Warnhinweise und Vorsichtsmaßnahmen)

  • Benazepril und HydrochlorothiazidACE-HemmerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Benzylpenicillin (Penicillin G)Penicillin-AntibiotikumGeringfügig

    Oxygen, intravenous steroids, and airway management, including intubation, should also be administered as indicated. (Fachinformation zu Benzylpenicillin (Penicillin G), Warnhinweise)

  • BevacizumabGeringfügig

    Discontinue in patients who develop a severe infusion-related reaction and administer appropriate medical therapy (e.g., epinephrine, corticosteroids, intravenous antihistamines, bronchodilators and/or oxygen). (Fachinformation zu Bevacizumab, Warnhinweise und Vorsichtsmaßnahmen)

  • Bisoprolol und HydrochlorothiazidBetablockerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BumetanidSchleifendiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • BusulfanGeringfügig

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (Fachinformation zu Busulfan, Warnhinweise)

  • CalcitriolVitamin-D-AnalogonGeringfügig

    Corticosteroids A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption. (Fachinformation zu Calcitriol, Arzneimittelwechselwirkungen)

  • Candesartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Cannabidiol (verschreibungspflichtig)AntiepileptikumGeringfügig

    Some subjects in the EPIDIOLEX clinical trials had pruritus, erythema, and angioedema requiring treatment, including corticosteroids and antihistamines. (Fachinformation zu Cannabidiol (verschreibungspflichtig), Warnhinweise und Vorsichtsmaßnahmen)

  • CefaclorCephalosporinGeringfügig

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Fachinformation zu Cefaclor, Warnhinweise)

  • CefadroxilCephalosporinGeringfügig

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Fachinformation zu Cefadroxil, Warnhinweise und Vorsichtsmaßnahmen)

  • CefdinirCephalosporinGeringfügig

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Fachinformation zu Cefdinir, Warnhinweise)

  • CefotetanCephalosporinGeringfügig

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Fachinformation zu Cefotetan, Warnhinweise)

  • CefprozilCephalosporinGeringfügig

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Fachinformation zu Cefprozil, Warnhinweise)

  • CeftazidimCephalosporinGeringfügig

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, IV FLUIDS, IV ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Fachinformation zu Ceftazidim, Warnhinweise)

  • CeftriaxonCephalosporinGeringfügig

    Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures including oxygen, corticosteroids, intravenous fluids, intravenous antihistamines, pressor amines, and airway management, as clinically indicated. (Fachinformation zu Ceftriaxon, Warnhinweise und Vorsichtsmaßnahmen)

  • ChininMalariamittelGeringfügig

    Drug/Laboratory Interactions Quinine may produce an elevated value for urinary 17-ketogenic steroids when the Zimmerman method is used. (Fachinformation zu Chinin, Arzneimittelwechselwirkungen)

  • ChlorothiazidThiaziddiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ChlortalidonThiaziddiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • ClofarabinAntimetabolitGeringfügig

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Fachinformation zu Clofarabin, Warnhinweise und Vorsichtsmaßnahmen)

  • Clomifenselektiver Estrogenrezeptormodulator (SERM)Geringfügig

    Elevated urinary steroid levels, varying degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. (Fachinformation zu Clomifen, Warnhinweise)

  • CorticotropinGeringfügig

    The recovery of the adrenal gland may take from days to months so patients should be protected from the stress (e.g., trauma or surgery) by the use of corticosteroids during the period of stress. (Fachinformation zu Corticotropin, Warnhinweise und Vorsichtsmaßnahmen)

  • DasatinibGeringfügig

    Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (Fachinformation zu Dasatinib, Warnhinweise und Vorsichtsmaßnahmen)

  • DexamfetaminZNS-StimulansGeringfügig

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Fachinformation zu Dexamfetamin, Arzneimittelwechselwirkungen)

  • DonepezilCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • DroperidolDopaminantagonistGeringfügig

    These would include diuretics, laxatives and supraphysiological use of steroid hormones with mineralocorticoid potential. (Fachinformation zu Droperidol, Arzneimittelwechselwirkungen)

  • Enalapril und HydrochlorothiazidACE-HemmerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EplerenonAldosteronantagonistGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EtacrynsäureSchleifendiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • EverolimusImmunsuppressivumGeringfügig

    Corticosteroids may be indicated until clinical symptoms resolve. (Fachinformation zu Everolimus, Warnhinweise und Vorsichtsmaßnahmen)

  • FludarabinAntimetabolitGeringfügig

    Steroids may or may not be effective in controlling these hemolytic episodes. (Fachinformation zu Fludarabin, Warnhinweise und Vorsichtsmaßnahmen)

  • FluoxetinSSRIGeringfügig

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (Fachinformation zu Fluoxetin, Warnhinweise und Vorsichtsmaßnahmen)

  • Fosinopril und HydrochlorothiazidACE-HemmerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • FurosemidSchleifendiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • GalantaminCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • GlucagonGeringfügig

    In the reported cases NME resolved with discontinuation of the glucagon, and treatment with corticosteroids was not effective. (Fachinformation zu Glucagon, Warnhinweise und Vorsichtsmaßnahmen)

  • GuselkumabImmunsuppressivumGeringfügig

    TREMFYA was subsequently discontinued, and the liver test abnormalities resolved following administration of corticosteroids [see Adverse Reactions (6.1) ] . (Fachinformation zu Guselkumab, Warnhinweise und Vorsichtsmaßnahmen)

  • HydrochlorothiazidThiaziddiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • IndapamidThiaziddiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • IpratropiumbromidAnticholinergikumGeringfügig

    ATROVENT HFA has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroids commonly used in the treatment of COPD. (Fachinformation zu Ipratropiumbromid, Arzneimittelwechselwirkungen)

  • Irbesartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • LenalidomidGeringfügig

    Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (Fachinformation zu Lenalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Losartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MelphalanGeringfügig

    The infusion should be terminated immediately, followed by the administration of volume expanders, pressor agents, corticosteroids, or antihistamines at the discretion of the physician. (Fachinformation zu Melphalan, Warnhinweise)

  • Memantin und DonepezilCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MetamfetaminZNS-StimulansGeringfügig

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Fachinformation zu Metamfetamin, Arzneimittelwechselwirkungen)

  • Metoprolol und HydrochlorothiazidBetablockerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • MidodrinAlpha-Adrenozeptor-AgonistGeringfügig

    Midodrine hydrochloride has been used in patients concomitantly treated with salt-retaining steroid therapy (i.e., fludrocortisone acetate), with or without salt supplementation. (Fachinformation zu Midodrin, Arzneimittelwechselwirkungen)

  • MitoxantronGeringfügig

    Following concurrent administration of mitoxantrone injection with corticosteroids, no evidence of drug interactions has been observed. (Fachinformation zu Mitoxantron, Arzneimittelwechselwirkungen)

  • NaltrexonOpioidantagonistGeringfügig

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (Fachinformation zu Naltrexon, Warnhinweise und Vorsichtsmaßnahmen)

  • NeostigminCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Olanzapin und FluoxetinAntipsychotikumGeringfügig

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (Fachinformation zu Olanzapin und Fluoxetin, Warnhinweise und Vorsichtsmaßnahmen)

  • Olmesartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Olmesartan, Amlodipin und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • OxacillinPenicillin-AntibiotikumGeringfügig

    If an allergic reaction occurs, the drug should be discontinued and the patient should receive supportive treatment, e.g. , artificial maintenance of ventilation, pressor amines, antihistamines, and corticosteroids. (Fachinformation zu Oxacillin, Warnhinweise)

  • Phenoxymethylpenicillin (Penicillin V)Penicillin-AntibiotikumGeringfügig

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (Fachinformation zu Phenoxymethylpenicillin (Penicillin V), Warnhinweise)

  • PhysostigminCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • PropylthiouracilThyreostatikumGeringfügig

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (Fachinformation zu Propylthiouracil, Warnhinweise)

  • PyridostigminCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Quinapril und HydrochlorothiazidACE-HemmerGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Raloxifenselektiver Estrogenrezeptormodulator (SERM)Geringfügig

    Other Concomitant Medications EVISTA can be concomitantly administered with ampicillin, amoxicillin, antacids, corticosteroids, and digoxin [see Clinical Pharmacology ( 12.3 )] . (Fachinformation zu Raloxifen, Arzneimittelwechselwirkungen)

  • RituximabImmunsuppressivumGeringfügig

    For RA, GPA and MPA, and PV patients, methylprednisolone 100 mg intravenously or its equivalent is recommended 30 minutes prior to each infusion. (Fachinformation zu Rituximab, Warnhinweise und Vorsichtsmaßnahmen)

  • RivastigminCholinesterasehemmerGeringfügig

    Anticholinesterases : Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • SpironolactonAldosteronantagonistGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Spironolacton und HydrochlorothiazidAldosteronantagonistGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Telmisartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • TenecteplaseGeringfügig

    If symptoms of hypersensitivity occur, initiate appropriate therapy (e.g., antihistamines, corticosteroids, epinephrine). (Fachinformation zu Tenecteplase, Warnhinweise und Vorsichtsmaßnahmen)

  • ThiamazolThyreostatikumGeringfügig

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (Fachinformation zu Thiamazol, Warnhinweise)

  • TobramycinAminoglykosidGeringfügig

    In clinical studies, patients receiving TOBI Podhaler continued to take dornase alfa, bronchodilators, inhaled corticosteroids, and macrolides. (Fachinformation zu Tobramycin, Arzneimittelwechselwirkungen)

  • Triamterenkaliumsparendes DiuretikumGeringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • UstekinumabImmunsuppressivumGeringfügig

    Patients improved with discontinuation of therapy and in certain cases administration of corticosteroids. (Fachinformation zu Ustekinumab, Warnhinweise und Vorsichtsmaßnahmen)

  • Valsartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (Fachinformation zu Methylprednisolon, Arzneimittelwechselwirkungen)

  • Vitamin DVitamine und MineralstoffeGeringfügig

    Kortikosteroide wie Prednison verringern die Calciumaufnahme und beeinträchtigen den Vitamin-D-Stoffwechsel, was zum Knochenschwund beiträgt. (NIH Office of Dietary Supplements, Vitamin D)

  • ZiprasidonAntipsychotikumGeringfügig

    Most patients improved promptly with adjunctive treatment with antihistamines or steroids and/or upon discontinuation of ziprasidone, and all patients experiencing these reactions were reported to recover completely. (Fachinformation zu Ziprasidon, Warnhinweise und Vorsichtsmaßnahmen)

Keine relevante Wechselwirkung berichtet (1)

  • AminophyllinMethylxanthinKeine Wechselwirkung

    …dirithromycin enflurane famotidine felodipine finasteride hydrocortisone isoflurane isoniazid isradipine influenza vaccine ketoconazole lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative… (Fachinformation zu Aminophyllin, Arzneimittelwechselwirkungen)

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Im Wechselwirkungscheck öffnen

Keine medizinische Beratung. Der Schweregrad gibt die Formulierung der Fachinformation wieder, nicht Ihre persönlichen Umstände. Eine als „schwerwiegend“ eingestufte Wechselwirkung kann unter Aufsicht Routine sein, und eine „geringfügige“ kann bei hohen Dosen von Bedeutung sein. Fragen Sie in einer Apotheke nach.