Interações de Cefazolina

Cefazolina (Ancef, Kefzol), cefalosporina, tem 80 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 30; moderadas: 18; leves: 32; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (30)

  • Amoxicilinaantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Amoxicilina + clavulanato de potássioantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Ampicilinaantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Ampicilina + sulbactamantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefaclorcefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefadroxilacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefalexinacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefdinircefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefepimacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefiximacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefotaximacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefotetanacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefoxitinacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefpodoximacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefprozilacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CeftarolinacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CeftazidimacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CeftriaxonacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefuroximacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Dicloxacilinaantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • ErtapenémantibióticoGrave

    INVANZ is contraindicated in patients with known hypersensitivity to any component of this product or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams. (bula de Ertapeném, Contraindicações)

  • Fenoximetilpenicilina (penicilina V)antibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Imipeném + cilastatinaantibióticoGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (bula de Imipeném + cilastatina, Advertências e precauções)

  • Nafcilinaantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Oxacilinaantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • Co-administration of probenecid with Cefazolin for Injection is not recommended. (bula de Cefazolina, Interações medicamentosas)

  • Co-administration of probenecid with Cefazolin for Injection is not recommended. (bula de Cefazolina, Interações medicamentosas)

  • RifampicinaantibióticoGrave

    Postmarketing reports suggest that concomitant administration of high doses of cefazolin and rifampin may prolong the prothrombin time, leading to severe vitamin K–dependent coagulation disorders that may be life-threatening or fatal. (bula de Rifampicina, Advertências)

Interações moderadas (18)

  • Ácido etacrínicodiurético de alçaModerada

    Ethacrynic acid may increase the ototoxic potential of other drugs such as aminoglycoside and some cephalosporin antibiotics. (bula de Ácido etacrínico, Interações medicamentosas)

  • ApixabanaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • ArgatrobanaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • AztreonamantibióticoModerada

    Use caution when CAYSTON is administered to patients with a known allergic reaction to beta-lactams. (bula de Aztreonam, Advertências e precauções)

  • BivalirudinaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • DabigatranaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • EdoxabanaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • EnoxaparinaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • Fitomenadiona (vitamina K1)vitamina KModerada

    Prothrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicated (5.5) (bula de Cefazolina, Advertências e precauções)

  • FondaparinuxanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • Furosemidadiurético de alçaModerada

    Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (bula de Furosemida, Interações medicamentosas)

  • GentamicinaaminoglicosídeoModerada

    Increased nephrotoxicity has been reported following concomitant administration of aminoglycoside antibiotics and cephalosporins. (bula de Gentamicina, Interações medicamentosas)

  • HeparinaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • MicofenolatoimunossupressorModerada

    Examples Cyclosporine A, trimethoprim/sulfamethoxazole, bile acid sequestrants (cholestyramine), rifampin as well as aminoglycoside, cephalosporin, fluoroquinolone and penicillin classes of antimicrobials Drugs Modulating Glucuronidation Clinical Impact Concomitant use with drugs inducing glucuronidation decreases MPA systemic exposure, potentially reducing mycophenolate… (bula de Micofenolato, Interações medicamentosas)

  • ProtaminaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (bula de Protamina, Precauções)

  • RivaroxabanaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • VarfarinaanticoagulanteModerada

    Those at risk include patients with renal or hepatic impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. (bula de Cefazolina, Advertências e precauções)

  • Vitamina KVitaminas e mineraisModerada

    Prothrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicated (5.5) (bula de Cefazolina, Advertências e precauções)

Menções leves (32)

  • Ácido valproicoanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • AminofilinametilxantinaLeve

    Some drugs (e.g., cefazolin, cephalothin), however, may interfere with certain HPLC techniques. (bula de Aminofilina, Interações medicamentosas)

  • BrivaracetamanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • CarbamazepinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • CenobamatoanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • ClobazambenzodiazepínicoLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • ClonazepambenzodiazepínicoLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • EslicarbazepinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • EtossuximidaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • FelbamatoanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • FenitoínaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • FenobarbitalbarbitúricoLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • Fentermina + topiramatoestimulante do SNCLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • FosfenitoínaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • GabapentinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • LacosamidaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • LamotriginaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • LevetiracetamanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • MeropenémantibióticoLeve

    Before initiating therapy with Meropenem for injection, it is important to inquire about previous hypersensitivity reactions to penicillins, cephalosporins, other β-lactams, and other allergens. (bula de Meropeném, Advertências e precauções)

  • Mesuximida (metossuximida)anticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • OxcarbazepinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • PerampanelanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • PregabalinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • PrimidonaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • RufinamidaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • TeofilinametilxantinaLeve

    Some drugs (e.g. cefazolin, cephalothin), however, may interfere with certain HPLC techniques. (bula de Teofilina, Interações medicamentosas)

  • TiagabinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • TopiramatoanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • VigabatrinaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

  • ZonisamidaanticonvulsivanteLeve

    Anticonvulsant therapy should be continued in patients with known seizure disorders. (bula de Cefazolina, Advertências e precauções)

Verifique Cefazolina com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.