Interações de Cefotaxima

Cefotaxima (Claforan), cefalosporina, tem 77 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 19; moderadas: 50; leves: 8; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (19)

  • Amoxicilinaantibiótico da classe das penicilinasGrave

    AMOXIL is contraindicated in patients who have experienced a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to AMOXIL or to other β-lactam antibacterial drugs (e.g., penicillins and cephalosporins). (bula de Amoxicilina, Contraindicações)

  • Amoxicilina + clavulanato de potássioantibiótico da classe das penicilinasGrave

    History of a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to AUGMENTIN or to other beta‑lactams (e.g., penicillins or cephalosporins). (bula de Amoxicilina + clavulanato de potássio, Contraindicações)

  • Ampicilinaantibiótico da classe das penicilinasGrave

    CONTRAINDICATIONS The use of Ampicillin is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin or to other beta-lactam antibacterial drugs. (bula de Ampicilina, Contraindicações)

  • Ampicilina + sulbactamantibiótico da classe das penicilinasGrave

    CONTRAINDICATIONS The use of UNASYN is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or to other beta-lactam antibacterial drugs (e.g., penicillins and cephalosporins). (bula de Ampicilina + sulbactam, Contraindicações)

  • CefaclorcefalosporinaGrave

    CONTRAINDICATIONS Cefaclor extended-release tablets are contraindicated in patients with known hypersensitivity to cefaclor and other cephalosporins. (bula de Cefaclor, Contraindicações)

  • CefalexinacefalosporinaGrave

    Cephalexin is contraindicated in patients with known hypersensitivity to cephalexin or other members of the cephalosporin class of antibacterial drugs. (bula de Cefalexina, Contraindicações)

  • CefazolinacefalosporinaGrave

    Hypersensitivity to cefazolin or other cephalosporin class antibacterial drugs, penicillins, or other beta-lactams (4.1) (bula de Cefazolina, Contraindicações)

  • CefepimacefalosporinaGrave

    Patients with known immediate hypersensitivity reactions to cefepime or other cephalosporins, penicillins or other beta-lactam antibacterial drugs. (bula de Cefepima, Contraindicações)

  • CefiximacefalosporinaGrave

    Contraindicated in patients with known allergy to cefixime or other cephalosporins. (bula de Cefixima, Contraindicações)

  • CefoxitinacefalosporinaGrave

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (bula de Cefoxitina, Contraindicações)

  • CeftarolinacefalosporinaGrave

    CONTRAINDICATIONS Teflaro is contraindicated in patients with known serious hypersensitivity to ceftaroline or other members of the cephalosporin class. (bula de Ceftarolina, Contraindicações)

  • CeftriaxonacefalosporinaGrave

    Anaphylaxis to ceftriaxone or other cephalosporin class antibacterials, penicillins, or other beta-lactam antibacterials ( 4.1 ) (bula de Ceftriaxona, Contraindicações)

  • CefuroximacefalosporinaGrave

    Known hypersensitivity (e.g., anaphylaxis) to cefuroxime axetil or to other β-lactams (e.g., penicillins and cephalosporins). (bula de Cefuroxima, Contraindicações)

  • ErtapenémantibióticoGrave

    INVANZ is contraindicated in patients with known hypersensitivity to any component of this product or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams. (bula de Ertapeném, Contraindicações)

  • Imipeném + cilastatinaantibióticoGrave

    Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (bula de Imipeném + cilastatina, Advertências e precauções)

  • Nafcilinaantibiótico da classe das penicilinasGrave

    WARNINGS Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving beta-lactam antibacterial drugs. (bula de Nafcilina, Advertências)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasGrave

    Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (bula de Piperacilina + tazobactam, Contraindicações)

  • Administration of cefotaxime in excess of 6 grams/day should be avoided in patients receiving probenecid (see CLINICAL PHARMACOLOGY, Drug Interactions ). (bula de Cefotaxima, Interações medicamentosas)

  • Administration of cefotaxime in excess of 6 grams/day should be avoided in patients receiving probenecid (see CLINICAL PHARMACOLOGY, Drug Interactions ). (bula de Cefotaxima, Interações medicamentosas)

Interações moderadas (50)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Ácido etacrínicodiurético de alçaModerada

    Ethacrynic acid may increase the ototoxic potential of other drugs such as aminoglycoside and some cephalosporin antibiotics. (bula de Ácido etacrínico, Interações medicamentosas)

  • Ácido mefenâmicoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • AmicacinaaminoglicosídeoModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • AztreonamantibióticoModerada

    Use caution when CAYSTON is administered to patients with a known allergic reaction to beta-lactams. (bula de Aztreonam, Advertências e precauções)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasModerada

    THIS PRODUCT SHOULD BE GIVEN WITH CAUTION TO PATIENTS WITH TYPE I HYPERSENSITIVITY REACTIONS TO PENICILLIN. (bula de Cefotaxima, Advertências)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CefadroxilacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CefdinircefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CefotetanacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CefpodoximacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CefprozilacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CeftazidimacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CelecoxibeAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CetoprofenoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CetorolacoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • DiclofenacoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Dicloxacilinaantibiótico da classe das penicilinasModerada

    THIS PRODUCT SHOULD BE GIVEN WITH CAUTION TO PATIENTS WITH TYPE I HYPERSENSITIVITY REACTIONS TO PENICILLIN. (bula de Cefotaxima, Advertências)

  • DiflunisalAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • EtodolacoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • FenoprofenoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Fenoximetilpenicilina (penicilina V)antibiótico da classe das penicilinasModerada

    THIS PRODUCT SHOULD BE GIVEN WITH CAUTION TO PATIENTS WITH TYPE I HYPERSENSITIVITY REACTIONS TO PENICILLIN. (bula de Cefotaxima, Advertências)

  • FlurbiprofenoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Furosemidadiurético de alçaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • GentamicinaaminoglicosídeoModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • IbuprofenoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • IndometacinaAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • MeloxicamAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • MicofenolatoimunossupressorModerada

    Examples Cyclosporine A, trimethoprim/sulfamethoxazole, bile acid sequestrants (cholestyramine), rifampin as well as aminoglycoside, cephalosporin, fluoroquinolone and penicillin classes of antimicrobials Drugs Modulating Glucuronidation Clinical Impact Concomitant use with drugs inducing glucuronidation decreases MPA systemic exposure, potentially reducing mycophenolate… (bula de Micofenolato, Interações medicamentosas)

  • NabumetonaAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • NaproxenoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • NeomicinaaminoglicosídeoModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Oxacilinaantibiótico da classe das penicilinasModerada

    THIS PRODUCT SHOULD BE GIVEN WITH CAUTION TO PATIENTS WITH TYPE I HYPERSENSITIVITY REACTIONS TO PENICILLIN. (bula de Cefotaxima, Advertências)

  • OxaprozinaAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • PiroxicamAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • PlazomicinaaminoglicosídeoModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • ProtaminaModerada

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (bula de Protamina, Precauções)

  • SalsalatoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • SulindacoAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • Sumatriptana + naproxenotriptanoModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • TobramicinaaminoglicosídeoModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • TolmetinaAINEModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

Menções leves (8)

  • ÁlcoolÁlcoolLeve

    Additionally, no disulfiram-like reactions were reported in a study conducted in 22 healthy volunteers administered cefotaxime and ethanol. (bula de Cefotaxima, Interações medicamentosas)

  • Articaína + epinefrinaanestésico localLeve

    SERIOUS HYPERSENSITIVITY REACTIONS MAY REQUIRE EPINEPHRINE AND OTHER EMERGENCY MEASURES. (bula de Cefotaxima, Advertências)

  • Bupivacaína + epinefrinaanestésico localLeve

    SERIOUS HYPERSENSITIVITY REACTIONS MAY REQUIRE EPINEPHRINE AND OTHER EMERGENCY MEASURES. (bula de Cefotaxima, Advertências)

  • Dissulfiraminibidor da CYP2C9Leve

    Additionally, no disulfiram-like reactions were reported in a study conducted in 22 healthy volunteers administered cefotaxime and ethanol. (bula de Cefotaxima, Interações medicamentosas)

  • Epinefrina (adrenalina)simpaticomiméticoLeve

    SERIOUS HYPERSENSITIVITY REACTIONS MAY REQUIRE EPINEPHRINE AND OTHER EMERGENCY MEASURES. (bula de Cefotaxima, Advertências)

  • Lidocaína + epinefrinaanestésico localLeve

    SERIOUS HYPERSENSITIVITY REACTIONS MAY REQUIRE EPINEPHRINE AND OTHER EMERGENCY MEASURES. (bula de Cefotaxima, Advertências)

  • MeropenémantibióticoLeve

    Before initiating therapy with Meropenem for injection, it is important to inquire about previous hypersensitivity reactions to penicillins, cephalosporins, other β-lactams, and other allergens. (bula de Meropeném, Advertências e precauções)

  • Prilocaína + epinefrinaanestésico localLeve

    SERIOUS HYPERSENSITIVITY REACTIONS MAY REQUIRE EPINEPHRINE AND OTHER EMERGENCY MEASURES. (bula de Cefotaxima, Advertências)

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Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.