Interações de Clorotiazida

Clorotiazida (Diuril), diurético tiazídico, tem 395 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 35; moderadas: 311; leves: 47; casos em que uma bula relata não haver interação significativa: 2). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (35)

  • Acetazolamidainibidor da anidrase carbônicaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Ácido etacrínicodiurético de alçaGrave

    CONTRAINDICATIONS All diuretics, including ethacrynic acid, are contraindicated in anuria. (bula de Ácido etacrínico, Contraindicações)

  • Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (bula de Alfacoriogonadotropina, Advertências)

  • Amiloridadiurético poupador de potássioGrave

    Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (bula de Amilorida, Advertência em caixa preta)

  • Bicarbonato de sódioantiácidoGrave

    Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (bula de Bicarbonato de sódio, Contraindicações)

  • Brinzolamidainibidor da anidrase carbônicaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Bumetanidadiurético de alçaGrave

    WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (bula de Bumetanida, Advertência em caixa preta)

  • CiclosporinaimunossupressorGrave

    Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (bula de Ciclosporina, Interações medicamentosas)

  • Citrato de potássiosuplemento de potássioGrave

    The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (bula de Citrato de potássio, Interações medicamentosas)

  • ClozapinaantipsicóticoGrave

    Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (bula de Clozapina, Advertência em caixa preta)

  • CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (bula de Diazóxido, Contraindicações)

  • Diclorfenamidainibidor da anidrase carbônicaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • DofetilidaantiarrítmicoGrave

    In the DIAMOND trials, 1252 patients were treated with dofetilide and diuretics concomitantly, of whom 493 died compared to 508 deaths among the 1248 patients receiving placebo and diuretics. (bula de Dofetilida, Interações medicamentosas)

  • Dorzolamidainibidor da anidrase carbônicaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Dorzolamida + timololinibidor da anidrase carbônicaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Droperidolantagonista da dopaminaGrave

    Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (bula de Droperidol, Advertência em caixa preta)

  • Enalaprilateinibidor da ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Enalaprilate, Advertências)

  • Eplerenonaantagonista da aldosteronaGrave

    …• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (bula de Eplerenona, Contraindicações)

  • Eptifibatidaantiagregante plaquetárioGrave

    …of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (bula de Eptifibatida, Contraindicações)

  • Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (bula de Folitropina, Advertências e precauções)

  • GentamicinaaminoglicosídeoGrave

    The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Gentamicina, Advertência em caixa preta)

  • Avoid diuretics or laxatives in patients with diarrhea. (bula de Irinotecano, Advertências e precauções)

  • Itraconazolantifúngico azólicoGrave

    Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (bula de Itraconazol, Interações medicamentosas)

  • Metazolamidainibidor da anidrase carbônicaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Metolazonadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (bula de Metolazona, Advertências)

  • MinoxidilvasodilatadorGrave

    Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (bula de Minoxidil, Advertência em caixa preta)

  • NeomicinaaminoglicosídeoGrave

    The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Neomicina, Advertência em caixa preta)

  • Quinaprilinibidor da ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Quinapril, Advertências)

  • SulfadiazinasulfonamidaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Sulfadiazina de pratasulfonamidaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • SulfassalazinasulfonamidaGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Tadalafilainibidor da PDE5Grave

    …coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (bula de Tadalafila, Advertências e precauções)

  • Trióxido de arsêniomedicamento que prolonga o intervalo QTGrave

    The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (bula de Trióxido de arsênio, Advertências e precauções)

  • ZonisamidaanticonvulsivanteGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

Interações moderadas (311)

  • AcarboseantidiabéticoModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • AcebutololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Ácido mefenâmicoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Ácido zoledrônicobisfosfonatoModerada

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (bula de Ácido zoledrônico, Advertências e precauções)

  • ÁlcoolÁlcoolModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • AlfaepoetinaModerada

    Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (bula de Alfaepoetina, Advertências e precauções)

  • AlfuzosinaalfabloqueadorModerada

    Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (bula de Alfuzosina, Advertências e precauções)

  • Alisquirenoanti-hipertensivoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Alogliptinainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Alogliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Alopurinolinibidor da xantina oxidaseModerada

    Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (bula de Alopurinol, Advertências e precauções)

  • AmicacinaaminoglicosídeoModerada

    Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (bula de Amicacina, Interações medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (bula de Amiodarona, Advertências e precauções)

  • Anfepramona (dietilpropiona)estimulante do SNCModerada

    The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (bula de Anfepramona (dietilpropiona), Interações medicamentosas)

  • Anlodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Anlodipino + atorvastatinabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Anlodipino + benazeprilbloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Anlodipino + olmesartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Anlodipino + valsartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Arformoterolagonista beta-adrenérgicoModerada

    Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Arformoterol, Interações medicamentosas)

  • AripiprazolantipsicóticoModerada

    Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (bula de Aripiprazol, Interações medicamentosas)

  • Armodafinilaestimulante do SNCModerada

    There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (bula de Armodafinila, Advertências e precauções)

  • AsenapinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (bula de Asenapina, Advertências e precauções)

  • AtenololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Atenolol + clortalidonabetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Atomoxetinainibidor da recaptação de noradrenalinaModerada

    Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (bula de Atomoxetina, Interações medicamentosas)

  • Avanafilainibidor da PDE5Moderada

    • Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (bula de Avanafila, Advertências e precauções)

  • Azilsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Baclofenorelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • Beladona + ópioopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Benazeprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Benazepril + hidroclorotiazidainibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Benzfetaminaestimulante do SNCModerada

    Amphetamines may decrease the hypotensive effect of antihypertensives. (bula de Benzfetamina, Interações medicamentosas)

  • BetaxololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Bexagliflozinainibidor do SGLT2Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • BisoprololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Bisoprolol + hidroclorotiazidabetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • BortezomibeModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (bula de Bortezomibe, Advertências e precauções)

  • BrexpiprazolantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Brexpiprazol, Advertências e precauções)

  • Brimonidinaagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (bula de Brimonidina, Interações medicamentosas)

  • Brimonidina + timololagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (bula de Brimonidina + timolol, Interações medicamentosas)

  • Bromocriptinaagonista da dopaminaModerada

    Use caution in patients taking antihypertensive medications. (bula de Bromocriptina, Advertências e precauções)

  • Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (bula de Bronfeniramina + pseudoefedrina + dextrometorfano, Interações medicamentosas)

  • Budesonida + formoterolcorticosteroideModerada

    Diuretics: Use with caution. (bula de Budesonida + formoterol, Interações medicamentosas)

  • BuprenorfinaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Butalbital + paracetamolbarbitúricoModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • ButorfanolopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Calcitriolanálogo da vitamina DModerada

    Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (bula de Calcitriol, Interações medicamentosas)

  • Canagliflozinainibidor do SGLT2Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Candesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Captoprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • CarbamazepinaanticonvulsivanteModerada

    Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (bula de Carbamazepina, Advertências e precauções)

  • CarbidopaModerada

    Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (bula de Carbidopa, Interações medicamentosas)

  • Carbidopa + levodopamedicamento dopaminérgicoModerada

    Antihypertensive drugs: May cause symptomatic postural hypotension. (bula de Carbidopa + levodopa, Interações medicamentosas)

  • Carbidopa + levodopa + entacaponamedicamento dopaminérgicoModerada

    Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (bula de Carbidopa + levodopa + entacapona, Interações medicamentosas)

  • CariprazinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Cariprazina, Advertências e precauções)

  • Carisoprodolrelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • CarvedilolbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • CefepimacefalosporinaModerada

    Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (bula de Cefepima, Interações medicamentosas)

  • CeftazidimacefalosporinaModerada

    Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (bula de Ceftazidima, Interações medicamentosas)

  • CelecoxibeAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Cetoconazolantifúngico azólicoModerada

    Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (bula de Cetoconazol, Interações medicamentosas)

  • CetoprofenoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • CetorolacoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Ciclobenzaprinarelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • CiclofosfamidaimunossupressorModerada

    …inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (bula de Ciclofosfamida, Interações medicamentosas)

  • Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (bula de Ciclossilicato de zircônio sódico, Advertências e precauções)

  • CitalopramISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Citalopram, Advertências e precauções)

  • ClofarabinaantimetabólitoModerada

    Consider use of diuretics and/or albumin. (bula de Clofarabina, Advertências e precauções)

  • Clonidinaagonista alfa-adrenérgicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (bula de Cloreto de cálcio, Interações medicamentosas)

  • ClorpromazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Clorpromazina, Precauções)

  • Clortalidonadiurético tiazídicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Clorzoxazonarelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • CodeínaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Colestipolsequestrante de ácidos biliaresModerada

    Studies in humans show that the absorption of chlorothiazide as reflected in urinary excretion is markedly decreased even when administered one hour before colestipol hydrochloride. (bula de Colestipol, Interações medicamentosas)

  • Colestiraminasequestrante de ácidos biliaresModerada

    Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (bula de Colestiramina, Interações medicamentosas)

  • Dantrolenorelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • Dapagliflozinainibidor do SGLT2Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Dapagliflozina + metforminainibidor do SGLT2Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Desipraminaantidepressivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (bula de Desipramina, Advertências)

  • …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (bula de Desmopressina, Interações medicamentosas)

  • DesvenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (bula de Desvenlafaxina, Advertências e precauções)

  • Dexlansoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Dexlansoprazol, Advertências e precauções)

  • Dexmetilfenidatoestimulante do SNCModerada

    • Antihypertensive Drugs: Monitor blood pressure. (bula de Dexmetilfenidato, Interações medicamentosas)

  • DiclofenacoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • DiflunisalAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Digoxinaglicosídeo digitálicoModerada

    Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (bula de Digoxina, Advertências e precauções)

  • Diltiazembloqueador dos canais de cálcioModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • DoxazosinaalfabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Doxercalciferolanálogo da vitamina DModerada

    Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Doxercalciferol, Advertências e precauções)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (bula de Drospirenona + etinilestradiol, Advertências e precauções)

  • Dulaglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • DuloxetinaIRSNModerada

    The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (bula de Duloxetina, Advertências e precauções)

  • EluxadolinaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Empagliflozinainibidor do SGLT2Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Empagliflozina + metforminainibidor do SGLT2Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Enalaprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Enalapril + hidroclorotiazidainibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Epinefrina (adrenalina)simpaticomiméticoModerada

    …Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (bula de Epinefrina (adrenalina), Interações medicamentosas)

  • Epoprostenolanálogo de prostaglandinaModerada

    Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (bula de Epoprostenol, Interações medicamentosas)

  • EscitalopramISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • EsmololbetabloqueadorModerada

    Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (bula de Esmolol, Interações medicamentosas)

  • Esomeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Esomeprazol, Advertências e precauções)

  • Espironolactonaantagonista da aldosteronaModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • EtodolacoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Exenatidaagonista do receptor de GLP-1Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Felodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Fenelzinainibidor da MAOModerada

    …hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (bula de Fenelzina, Advertências)

  • FenobarbitalbarbitúricoModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • FenoprofenoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • FenoxibenzaminaalfabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • FentanilaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Fentermina + topiramatoestimulante do SNCModerada

    In addition, when phentermine and topiramate extended-release capsules are used in conjunction with nonpotassium sparing diuretics this may further potentiate potassium-wasting. (bula de Fentermina + topiramato, Advertências e precauções)

  • Fluconazolantifúngico azólicoModerada

    An effect of this magnitude should not necessitate a change in the fluconazole dose regimen in subjects receiving concomitant diuretics. (bula de Fluconazol, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (bula de Fludrocortisona, Interações medicamentosas)

  • FluoxetinaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Fluoxetina, Advertências e precauções)

  • FlurbiprofenoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Fluticasona + salmeterolcorticosteroideModerada

    Diuretics: Use with caution. (bula de Fluticasona + salmeterol, Interações medicamentosas)

  • FluvoxaminaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Fluvoxamina, Advertências e precauções)

  • Formoterolagonista beta-adrenérgicoModerada

    • Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Formoterol, Interações medicamentosas)

  • FoscarneteantiviralModerada

    When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (bula de Foscarnete, Interações medicamentosas)

  • Fosinoprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Fosinopril + hidroclorotiazidainibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Furosemidadiurético de alçaModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • GlibenclamidasulfonilureiaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Glibenclamida + metforminasulfonilureiaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • GlimepiridasulfonilureiaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • GlipizidasulfonilureiaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Guanfacinaagonista alfa-adrenérgicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • HaloperidolantipsicóticoModerada

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (bula de Haloperidol, Interações medicamentosas)

  • HidralazinavasodilatadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • HidrocodonaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • HidromorfonaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • IbuprofenoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • IloperidonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Iloperidona, Advertências e precauções)

  • Imipraminaantidepressivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (bula de Imipramina, Advertências)

  • Indapamidadiurético tiazídicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • IndometacinaAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Insulina asparteinsulinaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Insulina degludecainsulinaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Insulina detemirinsulinaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Insulina glarginainsulinaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Insulina lisproinsulinaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (bula de Iodeto de potássio, Interações medicamentosas)

  • Ipratrópio + salbutamolanticolinérgicoModerada

    Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (bula de Ipratrópio + salbutamol, Interações medicamentosas)

  • Irbesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Isradipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • LabetalolbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Lansoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Lansoprazol, Advertências e precauções)

  • LevomilnacipranaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (bula de Levomilnaciprana, Advertências e precauções)

  • LevorfanolopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Levossalbutamolagonista beta-adrenérgicoModerada

    Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (bula de Levossalbutamol, Interações medicamentosas)

  • Linagliptinainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Linagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • LinezolidaantibióticoModerada

    Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (bula de Linezolida, Advertências e precauções)

  • Liraglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Lisinoprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Lítiomedicamento serotoninérgicoModerada

    Lithium generally should not be given with diuretics (see PRECAUTIONS , Drug Interactions ). (bula de Clorotiazida, Advertências)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Losartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • LumateperonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (bula de Lumateperona, Advertências e precauções)

  • LurasidonaantipsicóticoModerada

    Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (bula de Lurasidona, Advertências e precauções)

  • Mecamilaminaanti-hipertensivoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • MeloxicamAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • MetadonaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Metaxalonarelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • MetforminabiguanidaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Metildopaanti-hipertensivoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Metilfenidatoestimulante do SNCModerada

    Antihypertensive Drugs: Monitor blood pressure. (bula de Metilfenidato, Interações medicamentosas)

  • Metocarbamolrelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • MetoexitalbarbitúricoModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • MetoprololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • MiglitolantidiabéticoModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • MilnacipranaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (bula de Milnaciprana, Advertências e precauções)

  • MirtazapinaantidepressivoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (bula de Mirtazapina, Advertências e precauções)

  • Modafinilaestimulante do SNCModerada

    However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (bula de Modafinila, Advertências e precauções)

  • Moexiprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • MorfinaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • NabumetonaAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • NadololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • NalbufinaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • NaproxenoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • NateglinidameglitinidaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • NebivololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (bula de Niacina (ácido nicotínico), Interações medicamentosas)

  • Nicardipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Nifedipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Nimodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (bula de Nimodipino, Interações medicamentosas)

  • Nisoldipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • NitroglicerinanitratoModerada

    Antihypertensives: Possible additive hypotensive effects. (bula de Nitroglicerina, Interações medicamentosas)

  • Nitroprusseto de sódiovasodilatadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • OlanzapinaantipsicóticoModerada

    …of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (bula de Olanzapina, Advertências e precauções)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    …and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Olanzapina + fluoxetina, Advertências e precauções)

  • OliceridinaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Olmesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Omeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol, Advertências e precauções)

  • Omeprazol + bicarbonato de sódioinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol + bicarbonato de sódio, Advertências e precauções)

  • Orfenadrinarelaxante muscularModerada

    Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • Skeletal Muscle Relaxants, Nondepolarizing (e.g., Tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Clorotiazida, Interações medicamentosas)

  • OxaprozinaAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • OxicodonaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • OximorfonaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • PaliperidonaantipsicóticoModerada

    Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Paliperidona, Advertências e precauções)

  • Pantoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Pantoprazol, Advertências e precauções)

  • Paracetamol + codeínaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Paricalcitolanálogo da vitamina DModerada

    The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Paricalcitol, Advertências e precauções)

  • ParoxetinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (bula de Paroxetina, Advertências e precauções)

  • PazopanibeModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Pentazocina + naloxonaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • PentoxifilinametilxantinaModerada

    Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (bula de Pentoxifilina, Interações medicamentosas)

  • Perindoprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Petidina (meperidina)opioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • PindololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • PioglitazonatiazolidinedionaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Pioglitazona + glimepiridatiazolidinedionaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Pioglitazona + metforminatiazolidinedionaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • PiroxicamAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • PrazosinaalfabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • PrimidonaanticonvulsivanteModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • ProclorperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Proclorperazina, Precauções)

  • Prometazina + codeínaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • PropranololbetabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • QuetiapinaantipsicóticoModerada

    Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Quetiapina, Advertências e precauções)

  • Quinapril + hidroclorotiazidainibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • QuinidinaantiarrítmicoModerada

    Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (bula de Quinidina, Interações medicamentosas)

  • Rabeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Rabeprazol, Advertências e precauções)

  • Ramiprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • RemifentanilaopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • RepaglinidameglitinidaModerada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • RiociguatevasodilatadorModerada

    Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (bula de Riociguate, Advertências e precauções)

  • RisperidonaantipsicóticoModerada

    Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (bula de Risperidona, Advertências e precauções)

  • Sacubitril + valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Salbutamolagonista beta-adrenérgicoModerada

    Diuretics: Use with caution. (bula de Salbutamol, Interações medicamentosas)

  • Salmeterolagonista beta-adrenérgicoModerada

    • Diuretics: Use with caution. (bula de Salmeterol, Interações medicamentosas)

  • SalsalatoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Saxagliptinainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Saxagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Semaglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • SertralinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Sertralina, Advertências e precauções)

  • Sildenafilainibidor da PDE5Moderada

    Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (bula de Sildenafila, Advertências e precauções)

  • SilodosinaalfabloqueadorModerada

    However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (bula de Silodosina, Advertências e precauções)

  • Sitagliptinainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Sitagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • SorafenibeModerada

    Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (bula de Sorafenibe, Advertências e precauções)

  • SotalolbetabloqueadorModerada

    Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (bula de Sotalol, Advertências e precauções)

  • SulindacoAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • Sumatriptana + naproxenotriptanoModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • SunitinibeModerada

    Initiate and/or adjust antihypertensive therapy as appropriate. (bula de Sunitinibe, Advertências e precauções)

  • Suxametônio (succinilcolina)bloqueador neuromuscularModerada

    Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (bula de Suxametônio (succinilcolina), Advertências e precauções)

  • TacrolimoimunossupressorModerada

    • Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (bula de Tacrolimo, Advertências e precauções)

  • TapentadolopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Telmisartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Telmisartana + anlodipinobloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • TerazosinaalfabloqueadorModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Terbutalinaagonista beta-adrenérgicoModerada

    Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (bula de Terbutalina, Precauções)

  • TestosteronaandrogênioModerada

    In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (bula de Testosterona, Advertências e precauções)

  • Tirzepatidaagonista do receptor de GLP-1Moderada

    Antidiabetic Drugs (Oral Agents and Insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Clorotiazida, Interações medicamentosas)

  • Tizanidinarelaxante muscularModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • TobramicinaaminoglicosídeoModerada

    Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (bula de Tobramicina, Interações medicamentosas)

  • TolmetinaAINEModerada

    Non-steroidal Anti-inflammatory Drugs (NSAIDs) Including Selective Cyclooxygenase-2 (COX-2) Inhibitors - In some patients, the administration of a non-steroidal anti-inflammatory agent including a selective COX-2 inhibitor can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. (bula de Clorotiazida, Interações medicamentosas)

  • TolvaptanaModerada

    Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (bula de Tolvaptana, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Toremifenomodulador seletivo do receptor de estrogênioModerada

    Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (bula de Toremifeno, Interações medicamentosas)

  • TramadolopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Tramadol + paracetamolopioideModerada

    Alcohol, Barbiturates, or Narcotics - potentiation of orthostatic hypotension may occur. (bula de Clorotiazida, Interações medicamentosas)

  • Trandolaprilinibidor da ECAModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • TrazodonaantidepressivoModerada

    Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (bula de Trazodona, Advertências e precauções)

  • Trianterenodiurético poupador de potássioModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • TrifluoperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Trifluoperazina, Precauções)

  • Umeclidínio + vilanterolanticolinérgicoModerada

    • Diuretics: Use with caution. (bula de Umeclidínio + vilanterol, Interações medicamentosas)

  • Valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • Vardenafilainibidor da PDE5Moderada

    Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (bula de Vardenafila, Interações medicamentosas)

  • VenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Venlafaxina, Advertências e precauções)

  • Verapamilbloqueador dos canais de cálcioModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Clorotiazida, Advertências)

  • VilazodonaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (bula de Vilazodona, Advertências e precauções)

  • Vitamina DVitaminas e mineraisModerada

    Os diuréticos tiazídicos reduzem a excreção de cálcio; combinado com suplementos de vitamina D e de cálcio, isso pode levar a hipercalcemia, especialmente em idosos. (NIH Office of Dietary Supplements, Vitamin D)

  • VortioxetinaantidepressivoModerada

    Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (bula de Vortioxetina, Advertências e precauções)

  • ZiprasidonaantipsicóticoModerada

    Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (bula de Ziprasidona, Advertências e precauções)

Menções leves (47)

  • Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (bula de Ambrisentana, Advertências e precauções)

  • Azelastina + fluticasonaanti-histamínicoLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • BeclometasonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasLeve

    These drugs include: aspirin, phenylbutazone, sulfonamides, indomethacin, thiazide diuretics, furosemide and ethacrynic acid. (bula de Benzilpenicilina (penicilina G), Interações medicamentosas)

  • BetametasonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Bosentanaindutor da CYP3A4Leve

    Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (bula de Bosentana, Advertências e precauções)

  • BudesonidacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • CálcioVitaminas e mineraisLeve

    Os diuréticos tiazídicos reduzem a excreção de cálcio, de modo que um consumo alto de cálcio pode elevar o cálcio no sangue. (NIH Office of Dietary Supplements, Calcium)

  • CiclesonidacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • ClobetasolcorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (bula de Corticotropina, Interações medicamentosas)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (bula de Dasatinibe, Advertências e precauções)

  • DeflazacortecorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Desogestrel + etinilestradiolanticoncepcional oralLeve

    If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (bula de Desogestrel + etinilestradiol, Advertências)

  • DesonidacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • DexametasonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Dextroanfetaminaestimulante do SNCLeve

    Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (bula de Dextroanfetamina, Interações medicamentosas)

  • Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (bula de Docetaxel, Advertências e precauções)

  • DronedaronaantiarrítmicoLeve

    Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (bula de Dronedarona, Advertências e precauções)

  • EfedrinasimpaticomiméticoLeve

    Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (bula de Efedrina, Interações medicamentosas)

  • In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Estrogênios esterificados + metiltestosterona, Advertências)

  • Finasteridainibidor da 5-alfa-redutaseLeve

    …clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (bula de Finasterida, Interações medicamentosas)

  • FlecainidaantiarrítmicoLeve

    Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (bula de Flecainida, Interações medicamentosas)

  • FlunisolidacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • FluocinonidacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • FluticasonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (bula de Gliconato de cálcio, Interações medicamentosas)

  • HalobetasolcorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • HidrocortisonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (bula de Icatibanto, Interações medicamentosas)

  • Imatinibeinibidor da CYP3A4Leve

    Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (bula de Imatinibe, Advertências e precauções)

  • Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (bula de Macitentana, Advertências e precauções)

  • MagnésioVitaminas e mineraisLeve

    O uso prolongado de diuréticos de alça e tiazídicos aumenta a perda de magnésio na urina. (NIH Office of Dietary Supplements, Magnesium)

  • MetilprednisolonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • MetiltestosteronaandrogênioLeve

    In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Metiltestosterona, Advertências)

  • MexiletinaantiarrítmicoLeve

    In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (bula de Mexiletina, Interações medicamentosas)

  • MometasonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Nortriptilinaantidepressivo tricíclicoLeve

    The antihypertensive action of guanethidine and similar agents may be blocked. (bula de Nortriptilina, Advertências)

  • Olopatadina + mometasonaanti-histamínicoLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasLeve

    Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (bula de Piperacilina + tazobactam, Advertências e precauções)

  • PotássioVitaminas e mineraisLeve

    Os diuréticos de alça e tiazídicos aumentam a perda de potássio; a suplementação às vezes é prescrita junto com eles. (NIH Office of Dietary Supplements, Potassium)

  • PrednisolonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • PrednisonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • Protriptilinaantidepressivo tricíclicoLeve

    Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (bula de Protriptilina, Advertências)

  • TerbinafinaantifúngicoLeve

    There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (bula de Terbinafina, Interações medicamentosas)

  • TriancinolonacorticosteroideLeve

    Corticosteroids, ACTH - intensified electrolyte depletion, particularly hypokalemia. (bula de Clorotiazida, Interações medicamentosas)

  • ZincoVitaminas e mineraisLeve

    Os diuréticos tiazídicos aumentam a perda de zinco na urina com o uso prolongado. (NIH Office of Dietary Supplements, Zinc)

Nenhuma interação significativa relatada (2)

  • PamidronatobisfosfonatoSem interação

    Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (bula de Pamidronato, Interações medicamentosas)

  • Ropinirolagonista da dopaminaSem interação

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (bula de Ropinirol, Interações medicamentosas)

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