Interações de Cocaína

Cocaína (Goprelto, Numbrino), anestésico local, tem 163 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 67; moderadas: 93; leves: 3; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (67)

  • Anfepramona (dietilpropiona)estimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Anfetaminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Anfetamina + dextroanfetaminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Arformoterolagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Armodafinilaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Articaína + epinefrinaanestésico localGrave

    Avoid use of additional vasoconstrictor agents such as epinephrine or phenylephrine with NUMBRINO. (bula de Cocaína, Advertências e precauções)

  • Benzfetaminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Budesonida + formoterolcorticosteroideGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Bupivacaínaanestésico localGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Bupivacaína + epinefrinaanestésico localGrave

    Avoid use of additional vasoconstrictor agents such as epinephrine or phenylephrine with NUMBRINO. (bula de Cocaína, Advertências e precauções)

  • WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Cetaminadepressor do SNCGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Cloroprocaínaanestésico localGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Desfluranoanestésico geralGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Dexmetilfenidatoestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Dextroanfetaminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Difenidraminaanti-histamínicoGrave

    Use as a Local Anesthetic Because of the risk of local necrosis, this drug should not be used as a local anesthetic. (bula de Difenidramina, Contraindicações)

  • Dissulfiraminibidor da CYP2C9Grave

    Avoid using NUMBRINO in patients taking disulfiram. (bula de Cocaína, Interações medicamentosas)

  • DobutaminasimpaticomiméticoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • DroxidopasimpaticomiméticoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • EfedrinasimpaticomiméticoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Epinefrina (adrenalina)simpaticomiméticoGrave

    Avoid use of additional vasoconstrictor agents such as epinephrine or phenylephrine with NUMBRINO. (bula de Cocaína, Advertências e precauções)

  • Ergotamina + cafeínaalcaloide do ergotGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • ErtapenémantibióticoGrave

    Due to the use of lidocaine HCl as a diluent, INVANZ administered intramuscularly is contraindicated in patients with a known hypersensitivity to local anesthetics of the amide type. (bula de Ertapeném, Contraindicações)

  • Etomidatoanestésico geralGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Fendimetrazinaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Fenelzinainibidor da MAOGrave

    Therefore, patients being treated with phenelzine sulfate should not take sympathomimetic drugs (including amphetamines, cocaine, methylphenidate, dopamine, epinephrine, and norepinephrine) or related compounds (including methyldopa, L-dopa, L-tryptophan, L-tyrosine, and phenylalanine). (bula de Fenelzina, Contraindicações)

  • FenilefrinadescongestionanteGrave

    Avoid use of additional vasoconstrictor agents such as epinephrine or phenylephrine with NUMBRINO. (bula de Cocaína, Advertências e precauções)

  • Fenterminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Fentermina + topiramatoestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Fluticasona + salmeterolcorticosteroideGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Formoterolagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Imipraminaantidepressivo tricíclicoGrave

    Avoid the use of preparations, such as decongestants and local anesthetics, that contain any sympathomimetic amine (e.g., epinephrine, norepinephrine), since it has been reported that tricyclic antidepressants can potentiate the effects of catecholamines. (bula de Imipramina, Interações medicamentosas)

  • Ipratrópio + salbutamolanticolinérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Isofluranoanestésico geralGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Levossalbutamolagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Lidocaínaanestésico localGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Lidocaína + epinefrinaanestésico localGrave

    Avoid use of additional vasoconstrictor agents such as epinephrine or phenylephrine with NUMBRINO. (bula de Cocaína, Advertências e precauções)

  • Lidocaína + prilocaínaanestésico localGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Lisdexanfetaminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Mepivacaínaanestésico localGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Metanfetaminaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Metilfenidatoestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • MetoexitalbarbitúricoGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Midodrinaagonista alfa-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Mirabegronaagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Modafinilaestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Naltrexona + bupropionaantagonista opioideGrave

    …nervous system tumor or infection, or metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia) excessive use of alcohol or sedatives, addiction to cocaine or stimulants, or withdrawal from sedatives patients with diabetes treated with insulin and/or oral diabetic medications (sulfonylureas and meglitinides) that may cause hypoglycemia… (bula de Naltrexona + bupropiona, Advertências e precauções)

  • WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • OximetazolinadescongestionanteGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Prilocaína + epinefrinaanestésico localGrave

    Avoid use of additional vasoconstrictor agents such as epinephrine or phenylephrine with NUMBRINO. (bula de Cocaína, Advertências e precauções)

  • ProcainamidaantiarrítmicoGrave

    Idiosyncratic Hypersensitivity: In patients sensitive to procaine or other ester-type local anesthetics, cross sensitivity to PA is unlikely. (bula de Procainamida, Contraindicações)

  • Propofoldepressor do SNCGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • PseudoefedrinadescongestionanteGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Ropivacaínaanestésico localGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Salbutamolagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Salmeterolagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Sevofluranoanestésico geralGrave

    NUMBRINO is contraindicated in: patients with a known history of hypersensitivity to cocaine hydrochloride, other ester-based local anesthetics, or any other component of the nasal solution [see Warnings and Precautions ( 5.5 )] . (bula de Cocaína, Contraindicações)

  • Solriamfetolestimulante do SNCGrave

    WARNING: ABUSE AND DEPENDENCE CNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence. (bula de Cocaína, Advertência em caixa preta)

  • Terbutalinaagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Umeclidínio + vilanterolanticolinérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

  • Vibegronaagonista beta-adrenérgicoGrave

    Known Hypersensitivity or Idiosyncrasy to the Sympathomimetic Amines NUMBRINO is contraindicated in patients with a known history of hypersensitivity to cocaine or to the components of the nasal solution. (bula de Cocaína, Advertências e precauções)

Interações moderadas (93)

  • Amitriptilinaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Amoxapinaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Azelastina + fluticasonaanti-histamínicoModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Azul de metilenoinibidor da MAOModerada

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (bula de Cocaína, Interações medicamentosas)

  • BeclometasonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • BetametasonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • BudesonidacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • BupropionaantidepressivoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • CiclesonidacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • CiclofosfamidaimunossupressorModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Cisatracúriobloqueador neuromuscularModerada

    Potentiation of Neuromuscular Blockade Certain drugs may enhance the neuromuscular blocking action of Cisatracurium Besylate Injection including inhalational anesthetics, antibiotics, magnesium salts, lithium, local anesthetics, procainamide and quinidine [see Drug Interactions ( 7.1 )] . (bula de Cisatracúrio, Advertências e precauções)

  • CitalopramISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • ClobetasolcorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Clomipraminaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • DeflazacortecorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Desipraminaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Desogestrel + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • DesonidacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • DesvenlafaxinaIRSNModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Deutetrabenazinainibidor do VMAT2Moderada

    Postganglionic Blocking Agents Agents such as reserpine potentiate cocaine-induced sympathetic stimulation; concurrent use may increase the risk of hypertension and cardiac arrhythmias that may be life-threatening. (bula de Cocaína, Interações medicamentosas)

  • DexametasonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Diacetato de etinodiol + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Donepezilainibidor da colinesteraseModerada

    Cholinesterase inhibitors: Concomitant administration may increase the risk of cocaine toxicity. (bula de Cocaína, Interações medicamentosas)

  • Doxepinaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • DuloxetinaIRSNModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • EscitalopramISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • EstradiolestrogênioModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Estradiol + dienogesteanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Estradiol + noretisteronaestrogênioModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Estrogênios conjugadosestrogênioModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • FentolaminaalfabloqueadorModerada

    Lidocaine and Epinephrine When OraVerse was administered as an intraoral submucosal injection 30 minutes after injection of a local anesthetic, 2% lidocaine HCl with 1:100,000 epinephrine, the lidocaine concentration increased immediately after OraVerse intraoral injection. (bula de Fentolamina, Interações medicamentosas)

  • Fisostigminainibidor da colinesteraseModerada

    Cholinesterase inhibitors: Concomitant administration may increase the risk of cocaine toxicity. (bula de Cocaína, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • FlunisolidacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • FluocinonidacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • FluoxetinaISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • FluticasonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • FluvoxaminaISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • FulvestrantoestrogênioModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Galantaminainibidor da colinesteraseModerada

    Cholinesterase inhibitors: Concomitant administration may increase the risk of cocaine toxicity. (bula de Cocaína, Interações medicamentosas)

  • HalobetasolcorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • • Local anesthetics: Hyaluronidase hastens onset and shortens duration of effect, increases incidence of systemic reactions ( 7.3 ) (bula de Hialuronidase, Interações medicamentosas)

  • HidrocortisonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • IsoniazidaantibióticoModerada

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (bula de Cocaína, Interações medicamentosas)

  • LevomilnacipranaIRSNModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • LevonorgestrelprogestinaModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Levonorgestrel + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • LinezolidaantibióticoModerada

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (bula de Cocaína, Interações medicamentosas)

  • MedroxiprogesteronaprogestinaModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • MegestrolprogestinaModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Memantina + donepezilainibidor da colinesteraseModerada

    Cholinesterase inhibitors: Concomitant administration may increase the risk of cocaine toxicity. (bula de Cocaína, Interações medicamentosas)

  • MetilprednisolonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • MidazolambenzodiazepínicoModerada

    Should such reactions occur, the response to each dose of midazolam and all other drugs, including local anesthetics, should be evaluated before proceeding. (bula de Midazolam, Advertências e precauções)

  • Mifepristonainibidor da CYP3A4Moderada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • MirtazapinaantidepressivoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • MometasonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • NefazodonaantidepressivoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Neostigminainibidor da colinesteraseModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • NoretisteronaprogestinaModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Noretisterona + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Norgestimato + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Norgestrel + etinilestradiolanticoncepcional oralModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Nortriptilinaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Olopatadina + mometasonaanti-histamínicoModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • ParoxetinaISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Piridostigminainibidor da colinesteraseModerada

    Cholinesterase inhibitors: Concomitant administration may increase the risk of cocaine toxicity. (bula de Cocaína, Interações medicamentosas)

  • PrednisolonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • PrednisonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • ProgesteronaprogestinaModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Prometazinaanti-histamínicoModerada

    It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. (bula de Prometazina, Advertências)

  • Prometazina + dextrometorfanoanti-histamínicoModerada

    It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. (bula de Prometazina + dextrometorfano, Advertências)

  • Protriptilinaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Rasagilinainibidor da MAOModerada

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (bula de Cocaína, Interações medicamentosas)

  • Rivastigminainibidor da colinesteraseModerada

    Cholinesterase inhibitors: Concomitant administration may increase the risk of cocaine toxicity. (bula de Cocaína, Interações medicamentosas)

  • Rocurôniobloqueador neuromuscularModerada

    Certain inhalation anesthetics, particularly enflurane and isoflurane, antibiotics, magnesium salts, lithium, local anesthetics, procainamide, and quinidine have been shown to increase the duration of neuromuscular block and decrease infusion requirements of neuromuscular blocking agents [see Drug Interactions ( 7.3 )] . (bula de Rocurônio, Advertências e precauções)

  • Selegilinainibidor da MAOModerada

    Monoamine-oxidase inhibitors: Concomitant administration may potentiate the effects and toxicity of monoamine-oxidase inhibitors. (bula de Cocaína, Interações medicamentosas)

  • SertralinaISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Tetrabenazinainibidor do VMAT2Moderada

    Postganglionic Blocking Agents Agents such as reserpine potentiate cocaine-induced sympathetic stimulation; concurrent use may increase the risk of hypertension and cardiac arrhythmias that may be life-threatening. (bula de Cocaína, Interações medicamentosas)

  • TiotepaModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Tranilciprominainibidor da MAOModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • TrazodonaantidepressivoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • TriancinolonacorticosteroideModerada

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (bula de Cocaína, Interações medicamentosas)

  • Trimipraminaantidepressivo tricíclicoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • Valbenazinainibidor do VMAT2Moderada

    Postganglionic Blocking Agents Agents such as reserpine potentiate cocaine-induced sympathetic stimulation; concurrent use may increase the risk of hypertension and cardiac arrhythmias that may be life-threatening. (bula de Cocaína, Interações medicamentosas)

  • VenlafaxinaIRSNModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • VilazodonaISRSModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

  • VortioxetinaantidepressivoModerada

    Sympathomimetics, postganglionic blocking agents, and tricyclic antidepressants: Concomitant administration may increase the risk of cardiovascular adverse reactions. (bula de Cocaína, Interações medicamentosas)

Menções leves (3)

  • Application-Associated Pain Even following use of a local anesthetic prior to administration of QUTENZA, patients may experience substantial procedural pain and burning upon application of QUTENZA and following removal of QUTENZA. (bula de Capsaicina, Advertências e precauções)

  • Ondansetronamedicamento que prolonga o intervalo QTLeve

    Interactions with general or local anesthetics have not been studied. (bula de Ondansetrona, Interações medicamentosas)

  • Ramelteonasedativo-hipnóticoLeve

    In addition, in vitro data indicate that ramelteon does not cause false-positive results for benzodiazepines, opiates, barbiturates, cocaine, cannabinoids, or amphetamines in two standard urine drug screening methods in vitro . (bula de Ramelteona, Advertências e precauções)

Verifique Cocaína com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.