Interações de Dinoprostona

Dinoprostona (Cervidil, Prepidil, Prostin E2), análogo de prostaglandina, tem 36 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 3; moderadas: 28; leves: 5; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (3)

  • CetorolacoAINEGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • …fatal, anaphylactic reactions to NSAIDs have been reported in such patients [see Warnings and Precautions (5.8 , 5.9) ] • Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to diclofenac sodium and misoprostol, other prostaglandins, or any components of the drug product [see Warnings and Precautions (5.8 , 5.10) ] • Pregnancy ( 4 ) (bula de Diclofenaco + misoprostol, Contraindicações)

  • Latanoprostaanálogo de prostaglandinaGrave

    The combined use of two or more prostaglandins, or prostaglandin analogs including XELPROS is not recommended. (bula de Latanoprosta, Interações medicamentosas)

Interações moderadas (28)

  • Ácido mefenâmicoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Ácido mefenâmico, Advertências e precauções)

  • AtenololbetabloqueadorModerada

    Concomitant use of prostaglandin synthase inhibiting drugs, e.g., indomethacin, may decrease the hypotensive effects of beta-blockers. (bula de Atenolol, Interações medicamentosas)

  • Atenolol + clortalidonabetabloqueadorModerada

    Concomitant use of prostaglandin synthase inhibiting drugs, e.g., indomethacin, may decrease the hypotensive effects of beta-blockers. (bula de Atenolol + clortalidona, Interações medicamentosas)

  • CelecoxibeAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Celecoxibe, Advertências e precauções)

  • CetoprofenoAINEModerada

    A second form of renal toxicity has been seen in patients with conditions leading to a reduction in renal blood flow or blood volume, where renal prostaglandins have a supportive role in the maintenance of renal blood flow. (bula de Cetoprofeno, Advertências e precauções)

  • DiclofenacoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Diclofenaco, Advertências e precauções)

  • DiflunisalAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Diflunisal, Advertências)

  • EtodolacoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Etodolaco, Advertências)

  • FenoprofenoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Fenoprofeno, Advertências e precauções)

  • FlurbiprofenoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Flurbiprofeno, Advertências e precauções)

  • Furosemidadiurético de alçaModerada

    Indomethacin Coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of furosemide in some patients by inhibiting prostaglandin synthesis. (bula de Furosemida, Interações medicamentosas)

  • Renal Toxicity and Hyperkalemia Renal Toxicity Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury.Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Hidrocodona + ibuprofeno, Advertências)

  • IbuprofenoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Ibuprofeno, Advertências e precauções)

  • Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Ibuprofeno + famotidina, Advertências e precauções)

  • IndometacinaAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Indometacina, Advertências e precauções)

  • MeloxicamAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Meloxicam, Advertências e precauções)

  • Metilergometrinaalcaloide do ergotModerada

    Caution should be exercised when methylergonovine maleate is used concurrently with other vasoconstrictors, ergot alkaloids, or prostaglandins. (bula de Metilergometrina, Interações medicamentosas)

  • NabumetonaAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Nabumetona, Advertências)

  • NaproxenoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Naproxeno, Advertências e precauções)

  • Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Naproxeno + esomeprazol, Advertências e precauções)

  • OcitocinaModerada

    Prostaglandins, including CERVIDIL, may potentiate the effect of oxytocin [see Drug Interactions (7) ] . (bula de Dinoprostona, Advertências e precauções)

  • OxaprozinaAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Oxaprozina, Advertências e precauções)

  • Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Paracetamol + ibuprofeno, Advertências e precauções)

  • PiroxicamAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Piroxicam, Advertências e precauções)

  • SalsalatoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • SulindacoAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion.In these patients, administration of a non-steroidal anti-inflammatory drug may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. (bula de Sulindaco, Advertências)

  • Sumatriptana + naproxenotriptanoModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Sumatriptana + naproxeno, Advertências e precauções)

  • TolmetinaAINEModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Tolmetina, Advertências)

Menções leves (5)

  • Carboprostaanálogo de prostaglandinaLeve

    Evidence from animal studies has suggested that certain other prostaglandins have some teratogenic potential. (bula de Carboprosta, Advertências)

  • Cloreto de potássiosuplemento de potássioLeve

    Nonsteroidal Anti-inflammatory Drugs (NSAIDs) NSAIDs may produce potassium retention by reducing renal synthesis of prostaglandin E and impairing the renin-angiotensin system. (bula de Cloreto de potássio, Interações medicamentosas)

  • EnoxaparinaanticoagulanteLeve

    Therapy consisting of prompt removal of the source of procoagulant material, replacement of depleted clotting factors and, in some cases, anti-coagulation with heparin should be instituted promptly. (bula de Dinoprostona, Advertências e precauções)

  • HeparinaanticoagulanteLeve

    Therapy consisting of prompt removal of the source of procoagulant material, replacement of depleted clotting factors and, in some cases, anti-coagulation with heparin should be instituted promptly. (bula de Dinoprostona, Advertências e precauções)

  • Treprostinilaanálogo de prostaglandinaLeve

    Bronchospasm Like other inhaled prostaglandins, Tyvaso may cause acute bronchospasm. (bula de Treprostinila, Advertências e precauções)

Verifique Dinoprostona com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

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Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.