Interações de Cetorolaco

Cetorolaco (Toradol, Sprix), AINE, tem 315 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 83; moderadas: 147; leves: 82; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (83)

  • CONCOMITANT USE WITH NSAIDs Ketorolac tromethamine is CONTRAINDICATED in patients currently receiving aspirin or NSAIDs because of the cumulative risk of inducing serious NSAID-related side effects. (bula de Cetorolaco, Advertência em caixa preta)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioGrave

    CONCOMITANT USE WITH NSAIDs Ketorolac tromethamine is CONTRAINDICATED in patients currently receiving aspirin or NSAIDs because of the cumulative risk of inducing serious NSAID-related side effects. (bula de Cetorolaco, Advertência em caixa preta)

  • Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Alprostadilanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • ApixabanaanticoagulanteGrave

    …risk of developing epidural or spinal hematomas in these patients include: • use of indwelling epidural catheters • concomitant use of other drugs that affect hemostasis, such as nonsteroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants • a history of traumatic or repeated epidural or spinal punctures • a history of spinal deformity… (bula de Apixabana, Advertência em caixa preta)

  • Beladona + ópioopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • Bimatoprostaanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • BuprenorfinaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • CONCOMITANT USE WITH NSAIDs Ketorolac tromethamine is CONTRAINDICATED in patients currently receiving aspirin or NSAIDs because of the cumulative risk of inducing serious NSAID-related side effects. (bula de Cetorolaco, Advertência em caixa preta)

  • CONCOMITANT USE WITH NSAIDs Ketorolac tromethamine is CONTRAINDICATED in patients currently receiving aspirin or NSAIDs because of the cumulative risk of inducing serious NSAID-related side effects. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • ButorfanolopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • Carboprostaanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • CelecoxibeAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • CetoprofenoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • CidofovirantiviralGrave

    Nephrotoxic agents Concomitant administration of cidofovir injection and agents with nephrotoxic potential [e.g., intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and nonsteroidal anti-inflammatory agents] is contraindicated. (bula de Cidofovir, Interações medicamentosas)

  • CodeínaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • DabigatranaanticoagulanteGrave

    …the risk of developing epidural or spinal hematomas in these patients include: use of indwelling epidural catheters concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants a history of traumatic or repeated epidural or spinal punctures a history of spinal deformity… (bula de Dabigatrana, Advertência em caixa preta)

  • DiclofenacoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • DiflunisalAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Dinoprostonaanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • EdoxabanaanticoagulanteGrave

    …the risk of developing epidural or spinal hematomas in these patients include: use of indwelling epidural catheters concomitant use of other drugs that affect hemostasis, such as nonsteroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants a history of traumatic or repeated epidural or spinal punctures a history of spinal deformity… (bula de Edoxabana, Advertência em caixa preta)

  • Avoid SYMFI with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple non-steroidal anti-inflammatory drugs [NSAIDs]) [see Drug Interactions (7.3) ] . (bula de Efavirenz + lamivudina + tenofovir, Advertências e precauções)

  • EluxadolinaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • EnoxaparinaanticoagulanteGrave

    …the risk of developing epidural or spinal hematomas in these patients include: Use of indwelling epidural catheters Concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, and other anticoagulants A history of traumatic or repeated epidural or spinal punctures A history of spinal deformity… (bula de Enoxaparina, Advertência em caixa preta)

  • COMPLERA should be avoided with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple nonsteroidal anti-inflammatory drugs [NSAIDs]) [see Drug Interactions (7.4) ]. (bula de Entricitabina + rilpivirina + tenofovir, Advertências e precauções)

  • Epoprostenolanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • EtodolacoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • FenoprofenoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • FentanilaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • FlurbiprofenoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • FondaparinuxanticoagulanteGrave

    …risk of developing epidural or spinal hematomas in these patients include: • use of indwelling epidural catheters • concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, or other anticoagulants • a history of traumatic or repeated epidural or spinal puncture • a history of spinal deformity… (bula de Fondaparinux, Advertência em caixa preta)

  • HidrocodonaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • HidromorfonaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • IbuprofenoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • IndometacinaAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Latanoprostaanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • LevorfanolopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • MeloxicamAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • MetadonaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • MetotrexatoimunossupressorGrave

    Unexpectedly severe and fatal gastrointestinal toxicity can occur with concomitant administration of XATMEP (primarily at high dosage) and nonsteroidal anti-inflammatory drugs (NSAIDs) [see Drug Interactions ( 7.1 )] . (bula de Metotrexato, Advertências e precauções)

  • Misoprostolanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

  • Montelucasteantagonista do receptor de leucotrienosGrave

    Patients with known aspirin sensitivity should continue to avoid aspirin or non-steroidal anti-inflammatory agents while taking SINGULAIR ( 5.4 ). (bula de Montelucaste, Advertências e precauções)

  • MorfinaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • NabumetonaAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • NalbufinaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • NaproxenoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • OliceridinaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • CONCOMITANT USE WITH NSAIDs Ketorolac tromethamine is CONTRAINDICATED in patients currently receiving aspirin or NSAIDs because of the cumulative risk of inducing serious NSAID-related side effects. (bula de Cetorolaco, Advertência em caixa preta)

  • OxaprozinaAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • OxicodonaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • OximorfonaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • PentoxifilinametilxantinaGrave

    The concomitant use of ketorolac tromethamine and pentoxifylline is contraindicated. (bula de Cetorolaco, Contraindicações)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • PiroxicamAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • PralatrexatoantimetabólitoGrave

    Avoid coadministration with probenecid or nonsteroidal anti-inflammatory drugs. (bula de Pralatrexato, Interações medicamentosas)

  • Prasugrelantiagregante plaquetárioGrave

    Additional risk factors for bleeding include: body weight <60 kg, propensity to bleed, concomitant use of medications that increase the risk of bleeding (e.g . , warfarin, heparin, fibrinolytic therapy, chronic use of nonsteroidal anti-inflammatory drugs [NSAIDs]) [see Warnings and Precautions (5.1) ] . (bula de Prasugrel, Advertência em caixa preta)

  • The concomitant use of ketorolac tromethamine and probenecid is contraindicated. (bula de Cetorolaco, Contraindicações)

  • The concomitant use of ketorolac tromethamine and probenecid is contraindicated. (bula de Cetorolaco, Contraindicações)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • RemifentanilaopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • RivaroxabanaanticoagulanteGrave

    …risk of developing epidural or spinal hematomas in these patients include: • use of indwelling epidural catheters • concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants • a history of traumatic or repeated epidural or spinal punctures • a history of spinal deformity… (bula de Rivaroxabana, Advertência em caixa preta)

  • SalsalatoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • SulindacoAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • TapentadolopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • TenofovirantirretroviralGrave

    VIREAD should be avoided with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple non-steroidal anti-inflammatory drugs [NSAIDs]) [see Drug Interactions (7.1) ] . (bula de Tenofovir, Advertências e precauções)

  • TolmetinaAINEGrave

    Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Cetorolaco, Contraindicações)

  • TramadolopioideGrave

    BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • BOXED WARNING Ketorolac tromethamine tablets, a nonsteroidal anti-inflammatory drug (NSAID), are indicated for the short-term (up to 5 days in adults), management of moderately severe acute pain that requires analgesia at the opioid level and only as continuation treatment following IV or IM dosing of ketorolac tromethamine, if necessary. (bula de Cetorolaco, Advertência em caixa preta)

  • Treprostinilaanálogo de prostaglandinaGrave

    Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine contractions, thus increasing the risk of uterine hemorrhage. (bula de Cetorolaco, Contraindicações)

Interações moderadas (147)

  • Acetazolamidainibidor da anidrase carbônicaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Ácido etacrínicodiurético de alçaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Ácido zoledrônicobisfosfonatoModerada

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Ácido zoledrônico, Interações medicamentosas)

  • AdefovirantiviralModerada

    However, this is of special importance in patients at risk of or having underlying renal dysfunction and patients taking concomitant nephrotoxic agents such as cyclosporine, tacrolimus, aminoglycosides, vancomycin and non-steroidal anti-inflammatory drugs [See Adverse Reactions (6.2) and Clinical Pharmacology (12.3) ]. (bula de Adefovir, Advertências e precauções)

  • AfatinibeModerada

    Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (bula de Afatinibe, Advertências e precauções)

  • ÁlcoolÁlcoolModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • AlendronatobisfosfonatoModerada

    Use caution when co-prescribing aspirin/nonsteroidal anti- inflammatory drugs that may worsen gastrointestinal irritation. (bula de Alendronato, Interações medicamentosas)

  • Alisquirenoanti-hipertensivoModerada

    …part on the activity of the RAAS (e.g., patients with renal artery stenosis, severe heart failure, post-myocardial infarction or volume depletion) or patients receiving ARB, ACEI or nonsteroidal anti-inflammatory drug (NSAID), including selective Cyclooxygenase-2 inhibitors (COX-2 inhibitors), therapy may be at particular risk for developing acute renal failure… (bula de Alisquireno, Advertências e precauções)

  • Amiloridadiurético poupador de potássioModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Anagrelidamedicamento que prolonga o intervalo QTModerada

    Monitor patients for bleeding, including those receiving concomitant therapy with other drugs known to cause bleeding (e.g., anticoagulants, PDE3 inhibitors, NSAIDs, antiplatelet agents, selective serotonin reuptake inhibitors) [see Drug Interactions (7.3) , Clinical Pharmacology (12.3) ] . (bula de Anagrelida, Advertências e precauções)

  • Anlodipino + benazeprilbloqueador dos canais de cálcio di-hidropiridínicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Anlodipino + olmesartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Anlodipino + valsartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • ArgatrobanaanticoagulanteModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Atenolol + clortalidonabetabloqueadorModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Azelastina + fluticasonaanti-histamínicoModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Azilsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • BalsalazidasalicilatoModerada

    Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • BeclometasonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Benazeprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Benazepril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • BetametasonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Bisoprolol + hidroclorotiazidabetabloqueadorModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • BivalirudinaanticoagulanteModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • BudesonidacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Budesonida + formoterolcorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Bumetanidadiurético de alçaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Candesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Captoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • CefotaximacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CiclesonidacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • CiclosporinaimunossupressorModerada

    In addition, concomitant use of NSAIDs with cyclosporine, particularly in the setting of dehydration, may potentiate renal dysfunction. (bula de Ciclosporina, Interações medicamentosas)

  • CiprofloxacinofluoroquinolonaModerada

    NSAIDs Use with caution Non-steroidal anti-inflammatory drugs (but not acetyl salicylic acid) in combination of very high doses of quinolones have been shown to provoke convulsions in pre-clinical studies and in postmarketing. (bula de Ciprofloxacino, Interações medicamentosas)

  • CitalopramISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Citrato de potássiosuplemento de potássioModerada

    Nonsteroidal Anti-inflammatory drugs (NSAIDs) monitor for hyperkalemia (7.4) (bula de Citrato de potássio, Interações medicamentosas)

  • ClobetasolcorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Clopidogrelantiagregante plaquetárioModerada

    Risk factors for bleeding include concomitant use of other drugs that increase the risk of bleeding (e.g., anticoagulants, antiplatelet agents, and chronic use of NSAIDs) [see Drug Interactions (7.4 , 7.5 , 7.6 , 7.7) ]. (bula de Clopidogrel, Advertências e precauções)

  • Cloreto de potássiosuplemento de potássioModerada

    Nonsteroidal anti-inflammatory drugs: Monitor for hyperkalemia ( 7.3 ) (bula de Cloreto de potássio, Interações medicamentosas)

  • Clorotiazidadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Clortalidonadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Dapagliflozinainibidor do SGLT2Moderada

    …↔ ↔ Valsartan (320 mg) 20 mg ↓12% [↓3%, ↓20%] ↔ Simvastatin (40 mg) 20 mg ↔ ↔ Anti-infective Agent Rifampin (600 mg once daily for 6 days) 10 mg ↓7% [↓22%, ↑11%] ↓22% [↓27%, ↓17%] Nonsteroidal Anti-inflammatory Agent Mefenamic Acid (loading dose of 500 mg followed by 14 doses of 250 mg every 6 hours) 10 mg ↑13% [↑3%, ↑24%] ↑51% [↑44%, ↑58%] ↔ = no change (geometric… (bula de Dapagliflozina, Interações medicamentosas)

  • Deferasiroxsuplemento de ferroModerada

    The risk of GI hemorrhage may be increased when administering Exjade in combination with drugs that have ulcerogenic or hemorrhagic potential, such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, oral bisphosphonates, or anticoagulants. (bula de Deferasirox, Advertências e precauções)

  • DeflazacortecorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (bula de Desmopressina, Interações medicamentosas)

  • DesonidacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • DesvenlafaxinaIRSNModerada

    • Increased Risk of Bleeding: Concomitant use of aspirin, NSAIDs, other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.4 ). (bula de Desvenlafaxina, Advertências e precauções)

  • DexametasonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Digoxinaglicosídeo digitálicoModerada

    Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • Donepezilainibidor da colinesteraseModerada

    Therefore, patients should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Donepezila, Advertências e precauções)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (bula de Drospirenona + etinilestradiol, Advertências e precauções)

  • DuloxetinaIRSNModerada

    Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and other anti-coagulants may add to this risk. (bula de Duloxetina, Advertências e precauções)

  • Patients taking tenofovir prodrugs who have impaired renal function and those taking nephrotoxic agents including non-steroidal anti-inflammatory drugs are at increased risk of developing renal-related adverse reactions. (bula de Elvitegravir + cobicistate + entricitabina + tenofovir, Advertências e precauções)

  • Enalaprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Enalapril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Enalaprilateinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Entricitabina + tenofovirantirretroviralModerada

    Individuals taking tenofovir prodrugs who have impaired renal function and those taking nephrotoxic agents including non-steroidal anti-inflammatory drugs are at increased risk of developing renal-related adverse reactions. (bula de Entricitabina + tenofovir, Advertências e precauções)

  • Eplerenonaantagonista da aldosteronaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Eptifibatidaantiagregante plaquetárioModerada

    Use of Thrombolytics, Anticoagulants, and Other Antiplatelet Agents Risk factors for bleeding include older age, a history of bleeding disorders, and concomitant use of drugs that increase the risk of bleeding (thrombolytics, oral anticoagulants, nonsteroidal anti-inflammatory drugs, and P2Y 12 inhibitors). (bula de Eptifibatida, Advertências e precauções)

  • ErlotinibeModerada

    Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (bula de Erlotinibe, Advertências e precauções)

  • EscitalopramISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Espironolactonaantagonista da aldosteronaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Febuxostateinibidor da xantina oxidaseModerada

    In order to prevent gout flares when ULORIC is initiated, concurrent prophylactic treatment with an NSAID or colchicine is recommended [see Dosage and Administration (2.4) ]. (bula de Febuxostate, Advertências e precauções)

  • Fluconazolantifúngico azólicoModerada

    Non-steroidal anti-inflammatory drugs The C max and AUC of flurbiprofen were increased by 23% and 81%, respectively, when coadministered with fluconazole compared to administration of flurbiprofen alone. (bula de Fluconazol, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • FlunisolidacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • FluocinonidacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • FluoxetinaISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • FluticasonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Fluticasona + salmeterolcorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • FluvoxaminaISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Fosinoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Fosinopril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Furosemidadiurético de alçaModerada

    Diuretics Clinical studies, as well as postmarketing observations, have shown that ketorolac tromethamine can reduce the natriuretic effect of furosemide and thiazides in some patients. (bula de Cetorolaco, Interações medicamentosas)

  • Galantaminainibidor da colinesteraseModerada

    Therefore, patients should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those with an increased risk for developing ulcers, e.g., those with a history of ulcer disease or patients using concurrent nonsteroidal anti-inflammatory drugs (NSAIDS). (bula de Galantamina, Advertências e precauções)

  • GlibenclamidasulfonilureiaModerada

    Drug Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking… (bula de Glibenclamida, Interações medicamentosas)

  • GlimepiridasulfonilureiaModerada

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (bula de Glimepirida, Interações medicamentosas)

  • GlipizidasulfonilureiaModerada

    …angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, nonsteroidal anti-inflammatory agents, chloramphenicol, probenecid, coumarins, voriconazole, H2 receptor antagonists, and quinolones. (bula de Glipizida, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaModerada

    Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (bula de Glipizida + metformina, Precauções)

  • HalobetasolcorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • HeparinaanticoagulanteModerada

    The concurrent use of ketorolac tromethamine and therapy that affects hemostasis, including prophylactic low-dose heparin (2500 to 5000 units q12h), warfarin and dextrans have not been studied extensively, but may also be associated with an increased risk of bleeding. (bula de Cetorolaco, Advertências e precauções)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • HidrocortisonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • IbandronatobisfosfonatoModerada

    Use caution when co-prescribing aspirin/nonsteroidal anti-inflammatory drugs that may worsen gastrointestinal irritation. (bula de Ibandronato, Interações medicamentosas)

  • Indapamidadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Irbesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Itraconazolantifúngico azólicoModerada

    Nonsteroidal Anti-Inflammatory Drugs Meloxicam Concomitant drug dose increase may be necessary. (bula de Itraconazol, Interações medicamentosas)

  • LevofloxacinofluoroquinolonaModerada

    Non-Steroidal Anti-Inflammatory Drugs The concomitant administration of a non-steroidal anti-inflammatory drug with a fluoroquinolone, including Levofloxacin in 5% Dextrose Injection, may increase the risk of CNS stimulation and convulsive seizures [see Warnings and Precautions (5.4) ]. (bula de Levofloxacino, Interações medicamentosas)

  • LevomilnacipranaIRSNModerada

    Increased Risk of Bleeding : Concomitant use of NSAIDs, aspirin, other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.5 ). (bula de Levomilnaciprana, Advertências e precauções)

  • Lisinoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Lítiomedicamento serotoninérgicoModerada

    Lithium NSAIDs have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance. (bula de Cetorolaco, Interações medicamentosas)

  • Losartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Memantina + donepezilainibidor da colinesteraseModerada

    Patients treated with NAMZARIC should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Memantina + donepezila, Advertências e precauções)

  • Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • MesalazinasalicilatoModerada

    Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • MetilprednisolonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Metolazonadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Mifepristonainibidor da CYP3A4Moderada

    When given concomitantly with mifepristone, drugs that are substrates of CYP2C8/2C9 (including non-steroidal anti-inflammatory drugs, warfarin, and repaglinide) should be used at the smallest recommended doses, and patients should be closely monitored for adverse effects. [See Clinical Pharmacology ( 12.3 )] 7.5 Drugs Metabolized by CYP2B6 Mifepristone is an… (bula de Mifepristona, Interações medicamentosas)

  • MilnacipranaIRSNModerada

    Caution patients about the risk of bleeding associated with the concomitant use of milnacipran hydrochloride and NSAIDs, aspirin, or other drugs that affect coagulation ( 5.9 ). (bula de Milnaciprana, Advertências e precauções)

  • Moexiprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • MometasonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • MoxifloxacinofluoroquinolonaModerada

    Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Although not observed with moxifloxacin in preclinical and clinical trials, the concomitant administration of a nonsteroidal anti-inflammatory drug with a quinolone may increase the risks of CNS stimulation and convulsions [see Warnings and Precautions ( 5.4 ), and Patient Counseling Information ( 17 )]. (bula de Moxifloxacino, Interações medicamentosas)

  • NateglinidameglitinidaModerada

    Table 2: Clinically Significant Drug Interactions with Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone),… (bula de Nateglinida, Interações medicamentosas)

  • NintedanibeModerada

    Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (bula de Nintedanibe, Advertências e precauções)

  • OfloxacinofluoroquinolonaModerada

    Non Steroidal Anti-Inflammatory Drugs The concomitant administration of a non-steroidal anti-inflammatory drug with a quinolone, including ofloxacin, may increase the risk of CNS stimulation and convulsive seizures (see WARNINGS and PRECAUTIONS , General ). (bula de Ofloxacino, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Olmesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Olopatadina + mometasonaanti-histamínicoModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • ParoxetinaISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Perindoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Pioglitazona + glimepiridatiazolidinedionaModerada

    …steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides, chloramphenicol, coumarins, probenecid and monoamine oxidase inhibitors. (bula de Pioglitazona + glimepirida, Interações medicamentosas)

  • PrednisolonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • PrednisonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Quinaprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Quinapril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Ramiprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Rivastigminainibidor da colinesteraseModerada

    Monitor patients using rivastigmine tartrate for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Rivastigmina, Advertências e precauções)

  • Sacubitril + valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • SertralinaISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Subsalicilato de bismutosalicilatoModerada

    Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • SulfassalazinasulfonamidaModerada

    Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • Tabaco e fumoTabaco e cannabisModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Telmisartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Telmisartana + anlodipinobloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • TofacitinibeimunossupressorModerada

    Promptly evaluate patients treated with XELJANZ/XELJANZ XR who may be at increased risk for gastrointestinal perforation (e.g., patients with a history of diverticulitis or taking NSAIDs) and who present with new onset abdominal symptoms for early identification of gastrointestinal perforation [see Adverse Reactions (6.1) ] . (bula de Tofacitinibe, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Trandolaprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • TrazodonaantidepressivoModerada

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.5 ). (bula de Trazodona, Advertências e precauções)

  • TriancinolonacorticosteroideModerada

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Cetorolaco, Advertências e precauções)

  • Trianterenodiurético poupador de potássioModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • UpadacitinibeimunossupressorModerada

    Monitor RINVOQ/RINVOQ LQ-treated patients who may be at risk for gastrointestinal perforation (e.g., patients with a history of diverticulitis and those taking concomitant medications including NSAIDs or corticosteroids). (bula de Upadacitinibe, Advertências e precauções)

  • Valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    ACE Inhibitors/Angiotensin II Receptor Antagonists Concomitant use of ACE inhibitors and/or angiotensin II receptor antagonists may increase the risk of renal impairment, particularly in volume-depleted patients. (bula de Cetorolaco, Interações medicamentosas)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Cetorolaco, Advertências e precauções)

  • VarfarinaanticoagulanteModerada

    The concurrent use of ketorolac tromethamine and therapy that affects hemostasis, including prophylactic low-dose heparin (2500 to 5000 units q12h), warfarin and dextrans have not been studied extensively, but may also be associated with an increased risk of bleeding. (bula de Cetorolaco, Advertências e precauções)

  • VenlafaxinaIRSNModerada

    Concomitant use of aspirin, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), warfarin, and other anticoagulants may add to this risk. (bula de Venlafaxina, Advertências e precauções)

  • VilazodonaISRSModerada

    Selective Serotonin Reuptake Inhibitors (SSRIs) There is an increased risk of gastrointestinal bleeding when selective serotonin reuptake inhibitors (SSRIs) are combined with NSAIDs. (bula de Cetorolaco, Interações medicamentosas)

  • Voriconazolantifúngico azólicoModerada

    NSAIDs Non-Steroidal Anti-Inflammatory Drug including. ibuprofen and diclofenac (CYP2C9 Inhibition) Increased Frequent monitoring for adverse reactions and toxicity related to NSAIDs. (bula de Voriconazol, Interações medicamentosas)

  • VortioxetinaantidepressivoModerada

    • Increased Risk of Bleeding : Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin, or other drugs that affect coagulation may increase risk ( 5.3 ). (bula de Vortioxetina, Advertências e precauções)

Menções leves (82)

  • AcebutololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Ácido valproicoanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • AlprazolambenzodiazepínicoLeve

    Psychoactive Drugs Hallucinations have been reported when ketorolac tromethamine was used in patients taking psychoactive drugs (fluoxetine, thiothixene, alprazolam). (bula de Cetorolaco, Interações medicamentosas)

  • Anlodipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Anlodipino + atorvastatinabloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • AtenololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Baclofenorelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • BetaxololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • BisoprololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • BrivaracetamanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • CarbamazepinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Carisoprodolrelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • CarvedilolbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • CenobamatoanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Ciclobenzaprinarelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • ClobazambenzodiazepínicoLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • ClonazepambenzodiazepínicoLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Clonidinaagonista alfa-adrenérgicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Clorzoxazonarelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • Dantrolenorelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • Diltiazembloqueador dos canais de cálcioLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • DoxazosinaalfabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • EslicarbazepinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • EtossuximidaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • FelbamatoanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Felodipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • FenitoínaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • FenobarbitalbarbitúricoLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • FenoxibenzaminaalfabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Fentermina + topiramatoestimulante do SNCLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Finasteridainibidor da 5-alfa-redutaseLeve

    …angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives without evidence of clinically significant adverse interactions. (bula de Finasterida, Interações medicamentosas)

  • FosfenitoínaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • GabapentinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (bula de Glibenclamida + metformina, Interações medicamentosas)

  • Guanfacinaagonista alfa-adrenérgicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • HidralazinavasodilatadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • InfliximabeimunossupressorLeve

    In RA, concomitant medications besides MTX were nonsteroidal anti-inflammatory agents (NSAIDs), folic acid, corticosteroids and/or narcotics. (bula de Infliximabe, Interações medicamentosas)

  • Isradipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • LabetalolbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • LacosamidaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • LamotriginaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (bula de Lenalidomida, Advertências e precauções)

  • LevetiracetamanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Levotiroxinahormônio tireoidianoLeve

    Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (bula de Levotiroxina, Interações medicamentosas)

  • Liotironinahormônio tireoidianoLeve

    Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement. (bula de Liotironina, Interações medicamentosas)

  • Lofexidinaagonista alfa-adrenérgicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Mecamilaminaanti-hipertensivoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Mesuximida (metossuximida)anticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Metaxalonarelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • Metildopaanti-hipertensivoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Metocarbamolrelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • MetoprololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • MinoxidilvasodilatadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • NadololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • NebivololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Nicardipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Nifedipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Nisoldipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Nitroprusseto de sódiovasodilatadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • Orfenadrinarelaxante muscularLeve

    Nondepolarizing Muscle Relaxants In postmarketing experience there have been reports of a possible interaction between ketorolac tromethamineIV/IMand nondepolarizing muscle relaxants that resulted in apnea. (bula de Cetorolaco, Interações medicamentosas)

  • OxcarbazepinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • PerampanelanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • PindololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • PrazosinaalfabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • PregabalinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • PrimidonaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • PropranololbetabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • RepaglinidameglitinidaLeve

    Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (bula de Repaglinida, Interações medicamentosas)

  • RisedronatobisfosfonatoLeve

    Aspirin/Nonsteroidal Anti-Inflammatory Drugs In the Phase 3 study comparing Risedronate sodium delayed-release 35 mg once-a-week immediately following breakfast and risedronate sodium 5 mg daily, 18% of NSAID users (any use) in both groups developed upper gastrointestinal adverse reactions. (bula de Risedronato, Interações medicamentosas)

  • RufinamidaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • TerazosinaalfabloqueadorLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • TiagabinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • TiotixenoantipsicóticoLeve

    Psychoactive Drugs Hallucinations have been reported when ketorolac tromethamine was used in patients taking psychoactive drugs (fluoxetine, thiothixene, alprazolam). (bula de Cetorolaco, Interações medicamentosas)

  • Tizanidinarelaxante muscularLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • TocilizumabeimunossupressorLeve

    Concomitant Drugs for Treatment of Adult Indications In RA patients, population pharmacokinetic analyses did not detect any effect of methotrexate (MTX), non-steroidal anti-inflammatory drugs or corticosteroids on tocilizumab clearance. (bula de Tocilizumabe, Interações medicamentosas)

  • TopiramatoanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • Verapamilbloqueador dos canais de cálcioLeve

    Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE inhibitors and/or angiotensin II receptor antagonists. (bula de Cetorolaco, Interações medicamentosas)

  • VigabatrinaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

  • ZonisamidaanticonvulsivanteLeve

    Antiepileptic Drugs Sporadic cases of seizures have been reported during concomitant use of ketorolac tromethamine and antiepileptic drugs (phenytoin, carbamazepine). (bula de Cetorolaco, Interações medicamentosas)

Nenhuma interação significativa relatada (3)

  • Butalbital + paracetamolbarbitúricoSem interação

    Therapeutic concentrations of digoxin, warfarin, ibuprofen, naproxen, piroxicam, acetaminophen, phenytoin and tolbutamide did not alter ketorolac tromethamine protein binding. (bula de Cetorolaco, Interações medicamentosas)

  • Butalbital + paracetamol + cafeínabarbitúricoSem interação

    Therapeutic concentrations of digoxin, warfarin, ibuprofen, naproxen, piroxicam, acetaminophen, phenytoin and tolbutamide did not alter ketorolac tromethamine protein binding. (bula de Cetorolaco, Interações medicamentosas)

  • ParacetamolSem interação

    Therapeutic concentrations of digoxin, warfarin, ibuprofen, naproxen, piroxicam, acetaminophen, phenytoin and tolbutamide did not alter ketorolac tromethamine protein binding. (bula de Cetorolaco, Interações medicamentosas)

Verifique Cetorolaco com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.