Interações de Metronidazol

Metronidazol (Flagyl), antibiótico, tem 121 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 8; moderadas: 101; leves: 9; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (8)

  • ÁlcoolÁlcoolGrave

    Patients who consume alcohol or products containing propylene glycol during and for at least three days after LIKMEZ therapy. (bula de Metronidazol, Contraindicações)

  • Bosentanaindutor da CYP3A4Grave

    Co-administration of such combinations of a CYP2C9 inhibitor plus a strong or moderate CYP3A inhibitor with TRACLEER is not recommended. (bula de Bosentana, Interações medicamentosas)

  • Busulfan : Increased busulfan serum concentrations; avoid concomitant use, monitor for plasma concentrations and adjust the busulfan dose accordingly. (bula de Metronidazol, Interações medicamentosas)

  • Dissulfiraminibidor da CYP2C9Grave

    Patients who have used disulfiram within the last two weeks. (bula de Metronidazol, Contraindicações)

  • DronabinolcanabinoideGrave

    …reactions to dronabinol include lip swelling, hives, disseminated rash, oral lesions, skin burning, flushing, throat tightness [see Adverse Reactions ( 6.2 )] . with a history of a hypersensitivity reaction to alcohol. who are receiving, or have recently received, disulfiram- or metronidazole-containing products within 14 days [see Warning and Precautions ( 5.3 )] . (bula de Dronabinol, Contraindicações)

  • Moderate dual CYP3A4 and CYP2C9 inhibitors (fluconazole, amiodarone) or use of combined CYP3A4 and CYP2C9 inhibitors may increase exposure to macitentan: avoid co-administration with OPSUMIT ( 7.3 , 12.3 ). (bula de Macitentana, Interações medicamentosas)

  • Avoid concomitant use of mebendazole and metronidazole ( 5.3 ) (bula de Mebendazol, Advertências e precauções)

  • TinidazolantibióticoGrave

    WARNING: POTENTIAL RISK FOR CARCINOGENICITY WARNING: POTENTIAL RISK FOR CARCINOGENICITY Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent [see Nonclinical Toxicology (13.1)]. (bula de Tinidazol, Advertência em caixa preta)

Interações moderadas (101)

  • AlfuzosinaalfabloqueadorModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Amitriptilinaantidepressivo tricíclicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Anagrelidamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • ApixabanaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • ArgatrobanaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • AsenapinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Avanafilainibidor da PDE5Moderada

    HIV Protease inhibitor — Ritonavir (600 mg twice daily), a strong CYP3A4 inhibitor, which also inhibits CYP2C9, increased avanafil 50 mg single-dose C max and AUC equal to approximately 2-fold and 13-fold, and prolonged the half-life of avanafil to approximately 9 hours in healthy volunteers. (bula de Avanafila, Interações medicamentosas)

  • Azitromicinaantibiótico macrolídeoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • BivalirudinaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • CarvedilolbetabloqueadorModerada

    Amiodarone Amiodarone and its metabolite desethyl amiodarone, inhibitors of CYP2C9, and P- glycoprotein increased concentrations of the S(-)-enantiomer of carvedilol by at least 2 fold [see Clinical Pharmacology (12.5) ]. (bula de Carvedilol, Interações medicamentosas)

  • CelecoxibeAINEModerada

    Co-administration of celecoxib with drugs that are known to inhibit CYP2C9 (e.g., fluconazole) may enhance the exposure and toxicity of celecoxib whereas co-administration with CYP2C9 inducers (e.g., rifampin) may lead to compromised efficacy of celecoxib. (bula de Celecoxibe, Interações medicamentosas)

  • Cetoconazolantifúngico azólicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • CiclofosfamidaimunossupressorModerada

    Monitor for neurologic toxicities in patients receiving metronidazole. (bula de Ciclofosfamida, Interações medicamentosas)

  • Cimetidinabloqueador H2Moderada

    Inhibitors of CYP450 Liver Enzymes The simultaneous administration of LIKMEZ and drugs that decrease microsomal liver enzymes, such as cimetidine, may prolong the half-life and decrease plasma clearance of metronidazole. (bula de Metronidazol, Interações medicamentosas)

  • CiprofloxacinofluoroquinolonaModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • CitalopramISRSModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Claritromicinaantibiótico macrolídeoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • CloroquinaantimaláricoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • ClorpromazinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • ClozapinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • DabigatranaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • Deutetrabenazinainibidor do VMAT2Moderada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Dextrometorfano + quinidinamedicamento serotoninérgicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • DiclofenacoAINEModerada

    Co-administration of diclofenac with CYP2C9 inhibitors (e.g. voriconazole) may enhance the exposure and toxicity of diclofenac whereas co- administration with CYP2C9 inducers (e.g. rifampin) may lead to compromised efficacy of diclofenac. (bula de Diclofenaco, Interações medicamentosas)

  • Co-administration of diclofenac with CYP2C9 inhibitors (e.g., voriconazole) may enhance the exposure and toxicity of diclofenac [see Clinical Pharmacology (12.3) ] whereas co-administration with CYP2C9 inducers (e.g., rifampin) may lead to compromised efficacy of diclofenac. (bula de Diclofenaco + misoprostol, Interações medicamentosas)

  • DisopiramidaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • DofetilidaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • DronedaronaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Droperidolantagonista da dopaminaModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • EdoxabanaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • Effect of TRIKAFTA on Other Drugs CYP2C9 Substrates Ivacaftor may inhibit CYP2C9; therefore, monitoring of the international normalized ratio (INR) during concomitant use of TRIKAFTA with warfarin is recommended. (bula de Elexacaftor + tezacaftor + ivacaftor, Interações medicamentosas)

  • EnoxaparinaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • Eritromicinaantibiótico macrolídeoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • EscitalopramISRSModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • FenitoínaanticonvulsivanteModerada

    Inducers of CYP450 Liver Enzymes The simultaneous administration of LIKMEZ and drugs that induce microsomal liver enzymes, such as phenytoin or phenobarbital, may accelerate the elimination of metronidazole, resulting in reduced plasma concentrations of metronidazole. (bula de Metronidazol, Interações medicamentosas)

  • FenobarbitalbarbitúricoModerada

    Inducers of CYP450 Liver Enzymes The simultaneous administration of LIKMEZ and drugs that induce microsomal liver enzymes, such as phenytoin or phenobarbital, may accelerate the elimination of metronidazole, resulting in reduced plasma concentrations of metronidazole. (bula de Metronidazol, Interações medicamentosas)

  • Inducers of CYP450 Liver Enzymes The simultaneous administration of LIKMEZ and drugs that induce microsomal liver enzymes, such as phenytoin or phenobarbital, may accelerate the elimination of metronidazole, resulting in reduced plasma concentrations of metronidazole. (bula de Metronidazol, Interações medicamentosas)

  • FingolimodeimunossupressorModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • FlecainidaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Fluconazolantifúngico azólicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • FluoxetinaISRSModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • FondaparinuxanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • Granisetronamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • HaloperidolantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • HeparinaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • Hidroxicloroquinamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Hidroxizinaanti-histamínicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • IbutilidaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • IloperidonaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • LacosamidaanticonvulsivanteModerada

    Strong CYP3A4 or CYP2C9 Inhibitors Patients with renal or hepatic impairment who are taking strong inhibitors of CYP3A4 and CYP2C9 may have a significant increase in exposure to VIMPAT. (bula de Lacosamida, Interações medicamentosas)

  • LevofloxacinofluoroquinolonaModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Lítiomedicamento serotoninérgicoModerada

    Lithium: Increased lithium serum concentrations; measure serum lithium and serum creatinine concentrations during therapy. (bula de Metronidazol, Interações medicamentosas)

  • Loperamidamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • MeloxicamAINEModerada

    Thus concomitant usage of CYP2C9 inhibitors (such as amiodarone, fluconazole, and sulphaphenazole) may lead to abnormally high plasma levels of meloxicam due to reduced metabolic clearance [ see Use in Specific Populations ( 8.8 ); and Clinical Pharmacology ( 12.3 , 12.5 ) ]. (bula de Meloxicam, Interações medicamentosas)

  • MetadonaopioideModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • MoxifloxacinofluoroquinolonaModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • NateglinidameglitinidaModerada

    …salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan, thioctic acid, and inhibitors of CYP2C9 (e.g., amiodarone, fluconazole, voriconazole, sulfinpyrazone) or in patients known to be poor metabolizers of CYP2C9 substrates, alcohol. (bula de Nateglinida, Interações medicamentosas)

  • Nilotinibemedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • OfloxacinofluoroquinolonaModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Ondansetronamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • PaliperidonaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Pentamidinamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • PimavanserinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • PimozidaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Pitolisantomedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Posaconazolantifúngico azólicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • ProcainamidaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Prometazinaanti-histamínicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Prometazina + codeínaopioideModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Prometazina + dextrometorfanoanti-histamínicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • QuetiapinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • QuinidinaantiarrítmicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • QuininaantimaláricoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Ramelteonasedativo-hipnóticoModerada

    Fluconazole (strong CYP2C9 inhibitor): Increases systemic exposure of ramelteon; administer with caution. (bula de Ramelteona, Interações medicamentosas)

  • Ranolazinamedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • RisperidonaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • RivaroxabanaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • RosuvastatinaestatinaModerada

    Rosuvastatin plasma levels can be significantly increased with concomitant administration of inhibitors of CYP2C9 and transporters. (bula de Rosuvastatina, Interações medicamentosas)

  • SolifenacinaanticolinérgicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • SotalolbetabloqueadorModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Warfarin and other Oral Anticoagulants Metronidazole has been reported to potentiate the anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time. (bula de Metronidazol, Interações medicamentosas)

  • TacrolimoimunossupressorModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Tamoxifenomodulador seletivo do receptor de estrogênioModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Tetrabenazinainibidor do VMAT2Moderada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • TioridazinaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • TolterodinaanticolinérgicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Torasemidadiurético de alçaModerada

    CYP2C9: Concomitant use with CYP2C9 inhibitors can decrease torsemide clearance. (bula de Torasemida, Interações medicamentosas)

  • Toremifenomodulador seletivo do receptor de estrogênioModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • TramadolopioideModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Tramadol + paracetamolopioideModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • TrazodonaantidepressivoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Trióxido de arsêniomedicamento que prolonga o intervalo QTModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Valbenazinainibidor do VMAT2Moderada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Vardenafilainibidor da PDE5Moderada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • VarfarinaanticoagulanteModerada

    Warfarin and Other Oral Anticoagulants : LIKMEZ can potentiate the anticoagulant effect. (bula de Metronidazol, Interações medicamentosas)

  • VenlafaxinaIRSNModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Voriconazolantifúngico azólicoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

  • Zafirlucasteantagonista do receptor de leucotrienosModerada

    Zafirlukast exposure is likely to be increased by other moderate and strong CYP2C9 inhibitors. (bula de Zafirlucaste, Precauções)

  • ZiprasidonaantipsicóticoModerada

    Drugs that Prolong the QT Interval QT prolongation has been reported, particularly when metronidazole was administered with drugs with the potential for prolonging the QT interval. (bula de Metronidazol, Interações medicamentosas)

Menções leves (9)

  • Clopidogrelantiagregante plaquetárioLeve

    However, at high concentrations in vitro , clopidogrel inhibits CYP2C9. (bula de Clopidogrel, Interações medicamentosas)

  • Clotrimazolantifúngico azólicoLeve

    Fungal Superinfections Known or previously unrecognized candidiasis may present more prominent symptoms during therapy with LIKMEZ and requires treatment with an antifungal agent. (bula de Metronidazol, Advertências e precauções)

  • Econazolantifúngico azólicoLeve

    Fungal Superinfections Known or previously unrecognized candidiasis may present more prominent symptoms during therapy with LIKMEZ and requires treatment with an antifungal agent. (bula de Metronidazol, Advertências e precauções)

  • Ergotamina + cafeínaalcaloide do ergotLeve

    Examples of less potent CYP 3A4 inhibitors include: saquinavir, nefazodone, fluconazole, fluoxetine, grapefruit juice, fluvoxamine, zileuton, metronidazole, and clotrimazole. (bula de Ergotamina + cafeína, Advertências)

  • InfliximabeimunossupressorLeve

    Serum infliximab concentrations appeared to be unaffected by baseline use of medications for the treatment of CD including corticosteroids, antibiotics (metronidazole or ciprofloxacin) and aminosalicylates. (bula de Infliximabe, Interações medicamentosas)

  • Itraconazolantifúngico azólicoLeve

    Fungal Superinfections Known or previously unrecognized candidiasis may present more prominent symptoms during therapy with LIKMEZ and requires treatment with an antifungal agent. (bula de Metronidazol, Advertências e precauções)

  • Lopinavir + ritonavirantirretroviralLeve

    Disulfiram/metronidazole KALETRA oral solution contains ethanol, which can produce disulfiram-like reactions when co-administered with disulfiram or other drugs that produce this reaction (e.g., metronidazole). (bula de Lopinavir + ritonavir, Interações medicamentosas)

  • Miconazolantifúngico azólicoLeve

    Fungal Superinfections Known or previously unrecognized candidiasis may present more prominent symptoms during therapy with LIKMEZ and requires treatment with an antifungal agent. (bula de Metronidazol, Advertências e precauções)

  • TerbinafinaantifúngicoLeve

    Fluconazole is an inhibitor of CYP2C9 and CYP3A enzymes. (bula de Terbinafina, Interações medicamentosas)

Nenhuma interação significativa relatada (3)

  • AminofilinametilxantinaSem interação

    …enflurane famotidine felodipine finasteride hydrocortisone isoflurane isoniazid isradipine influenza vaccine ketoconazole lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not… (bula de Aminofilina, Interações medicamentosas)

  • Neostigminainibidor da colinesteraseSem interação

    There was no effect on neostigmine action on rocuronium reversal by cefuroxime, metronidazole, cefuroxime or metronidazole. (bula de Neostigmina, Interações medicamentosas)

  • TeofilinametilxantinaSem interação

    …clinically significant interaction with theophylline.* albuterol, systemic and inhaled mebendazole amoxicillin medroxyprogesterone ampicillin, with or without methylprednisolone sulbactam metronidazole atenolol metoprolol azithromycin nadolol caffeine, dietary ingestion nifedipine cefaclor nizatidine co-trimoxazole (trimethoprim and sulfamethoxazole) norfloxacin ofloxacin… (bula de Teofilina, Interações medicamentosas)

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Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.