Interações de Naltrexona

Naltrexona (Vivitrol, Revia), antagonista opioide, tem 77 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 40; moderadas: 3; leves: 31; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (40)

  • Beladona + ópioopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Opioid Antagonist: Naloxegol ↑ naloxegol Avoid use with BIXLENVO; if unavoidable, decrease the dosage of naloxegol and monitor for adverse reactions. (bula de Bictegravir + entricitabina + tenofovir alafenamida, Interações medicamentosas)

  • BuprenorfinaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Any individual who has failed the naloxone challenge test or has a positive urine screen for opioids [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • ButorfanolopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • CodeínaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • DarunavirantirretroviralGrave

    John's wort ( Hypericum perforatum ) Hepatitis C direct acting antiviral: elbasvir/grazoprevir Lipid modifying agents: lomitapide, lovastatin, simvastatin Opioid Antagonist: naloxegol PDE-5 inhibitor: sildenafil when used for treatment of pulmonary arterial hypertension Sedatives/hypnotics: orally administered midazolam, triazolam Co-administration of PREZISTA/ritonavir… (bula de Darunavir, Contraindicações)

  • Darunavir + cobicistateantirretroviralGrave

    John's wort ( Hypericum perforatum ) Hepatitis C direct acting antiviral: elbasvir/grazoprevir Lipid modifying agents: lomitapide, lovastatin, simvastatin Opioid Antagonist: naloxegol PDE-5 inhibitor: sildenafil when used for treatment of pulmonary arterial hypertension Sedatives/hypnotics: orally administered midazolam, triazolam PREZCOBIX or PREZCOBIX PED is… (bula de Darunavir + cobicistate, Contraindicações)

  • EluxadolinaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • FentanilaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • HidrocodonaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • HidromorfonaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • LenacapavirantirretroviralGrave

    Opioid Antagonist: naloxegol ↑ naloxegol Avoid use with SUNLENCA; if unavoidable, decrease the dosage of naloxegol and monitor for adverse reactions. (bula de Lenacapavir, Interações medicamentosas)

  • LevorfanolopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • MetadonaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Metilnaltrexonaantagonista opioideGrave

    • Other Opioid Antagonists : Potential for additive effect and increased risk of opioid withdrawal; avoid concomitant use. (bula de Metilnaltrexona, Interações medicamentosas)

  • MorfinaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • NalbufinaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naldemedinaantagonista opioideGrave

    Intervention Avoid use of SYMPROIC with another opioid antagonist. (bula de Naldemedina, Interações medicamentosas)

  • Naloxegolantagonista opioideGrave

    Other opioid antagonists : Potential for additive effect and increased risk of opioid withdrawal; avoid concomitant use. (bula de Naloxegol, Interações medicamentosas)

  • Naloxonaantagonista opioideGrave

    Any individual who has failed the naloxone challenge test or has a positive urine screen for opioids [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • …Migraine medications: eletriptan, ubrogepant • Mineralocorticoid receptor antagonists: finerenone • Non-opioid analgesic (selective blocker of Na v 1.8 sodium channels): suzetrigine • Opioid antagonists: naloxegol • PDE5 inhibitor: sildenafil (Revatio ® ) when used for pulmonary arterial hypertension (PAH) • Sedative/hypnotics: triazolam, oral midazolam • Serotonin… (bula de Nirmatrelvir + ritonavir, Contraindicações)

  • OliceridinaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • OxicodonaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • OximorfonaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Any individual who has failed the naloxone challenge test or has a positive urine screen for opioids [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • RemifentanilaopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • TapentadolopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • TramadolopioideGrave

    Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

  • Naltrexone for extended-release injectable suspension is contraindicated in: Patients receiving opioid analgesics [see Warnings and Precautions ( 5.3 ) ] . (bula de Naltrexona, Contraindicações)

Interações moderadas (3)

  • EtravirinaantirretroviralModerada

    Narcotic analgesics/treatment of opioid dependence: buprenorphine buprenorphine/naloxone methadone ↔ etravirine ↓ buprenorphine ↔ norbuprenorphine ↔ methadone Etravirine and buprenorphine (or buprenorphine/naloxone) can be co-administered without dose adjustments, however, clinical monitoring for withdrawal symptoms is recommended as buprenorphine (or buprenorphine/naloxone)… (bula de Etravirina, Interações medicamentosas)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Oral Naltrexone : Concomitant use may reduce efficacy of oral naltrexone. (bula de Lofexidina, Interações medicamentosas)

  • Nalmefenoantagonista opioideModerada

    Strongly consider recommending or prescribing an opioid reversal agent (e.g., naloxone, nalmefene) for the emergency treatment of opioid overdose (5.1) . (bula de Naltrexona, Advertências e precauções)

Menções leves (31)

  • ÁlcoolÁlcoolLeve

    Precipitation of Opioid Withdrawal : Opioid-dependent and opioid-using patients, including those being treated for alcohol dependence, should be opioid-free before starting naltrexone for extended-release injectable suspension treatment, and should notify healthcare providers of any recent opioid use. (bula de Naltrexona, Advertências e precauções)

  • Azelastina + fluticasonaanti-histamínicoLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • BeclometasonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • BetametasonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • BudesonidacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Budesonida + formoterolcorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Cetaminadepressor do SNCLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • CiclesonidacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • ClobetasolcorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • DeflazacortecorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Desfluranoanestésico geralLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • DesonidacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • DexametasonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Etomidatoanestésico geralLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • FludrocortisonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • FlunisolidacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • FluocinonidacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • FluticasonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Fluticasona + salmeterolcorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • HalobetasolcorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • HidrocortisonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Isofluranoanestésico geralLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • MetilprednisolonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • MetoexitalbarbitúricoLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • MometasonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Olopatadina + mometasonaanti-histamínicoLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • PrednisolonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • PrednisonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

  • Propofoldepressor do SNCLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • Sevofluranoanestésico geralLeve

    The opioid therapy must be provided by individuals specifically trained in the use of anesthetic drugs and the management of the respiratory effects of potent opioids, specifically the establishment and maintenance of a patent airway and assisted ventilation. (bula de Naltrexona, Advertências e precauções)

  • TriancinolonacorticosteroideLeve

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (bula de Naltrexona, Advertências e precauções)

Nenhuma interação significativa relatada (3)

  • AcamprosatoSem interação

    The pharmacokinetics of acamprosate are not affected by alcohol, diazepam, or disulfiram, and clinically important interactions between naltrexone and acamprosate were not observed [ see Clinical Pharmacology ( 12.3 ) ]. (bula de Acamprosato, Interações medicamentosas)

  • Narcotic Analgesics: buprenorphine/ naloxone ↑ buprenorphine ↑ norbuprenorphine ↓ naloxone No dosage adjustment of buprenorphine/naloxone is required upon coadministration with GENVOYA. (bula de Elvitegravir + cobicistate + entricitabina + tenofovir, Interações medicamentosas)

  • Entricitabina + tenofovirantirretroviralSem interação

    No clinically significant drug interactions have been either observed or are expected when DESCOVY is combined with the following drugs: buprenorphine, itraconazole, ketoconazole, lorazepam, methadone, midazolam, naloxone, norbuprenorphine, norgestimate/ethinyl estradiol, and sertraline. (bula de Entricitabina + tenofovir, Interações medicamentosas)

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