Interações de Octreotida
Octreotida (Sandostatin, Bynfezia, Mycapssa) tem 125 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 0; moderadas: 125; leves: 0; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.
Interações segundo a bula
Interações moderadas (125)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Bromocriptine: dose adjustment of bromocriptine may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Cyclosporine : may have decreased bioavailability and require dose adjustment ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Drugs Metabolized by CYP 450 Enzymes: concomitant use with other drugs mainly metabolized by CYP3A4 that have a narrow therapeutic index (e.g., quinidine) should be used with caution and increased monitoring may be required ( 7 ). (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Digoxin: exposure may be decreased and assessment of clinical response to digoxin should be performed ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
- GlucagonModerada
Hyperglycemia and Hypoglycemia MYCAPSSA alters the balance between the counter-regulatory hormones, insulin, glucagon, and growth hormone, which may result in hypoglycemia, or hyperglycemia, or diabetes mellitus. (bula de Octreotida, Advertências e precauções)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Levonorgestrel Clinical Impact: Concomitant administration of MYCAPSSA with levonorgestrel decreases levonorgestrel bioavailability [see Clinical Pharmacology (12.3) ] . (bula de Octreotida, Interações medicamentosas)
Levonorgestrel Clinical Impact: Concomitant administration of MYCAPSSA with levonorgestrel decreases levonorgestrel bioavailability [see Clinical Pharmacology (12.3) ] . (bula de Octreotida, Interações medicamentosas)
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Lisinopril: bioavailability may be increased, monitor patient's blood pressure and adjust dose of lisinopril if needed ( 7 ). (bula de Octreotida, Interações medicamentosas)
Lisinopril: bioavailability may be increased, monitor patient's blood pressure and adjust dose of lisinopril if needed ( 7 ). (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Intervention: Decreased bioavailability may potentially diminish the effectiveness of combined oral contraceptives (COCs) or increase breakthrough bleeding. (bula de Octreotida, Interações medicamentosas)
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Drugs Metabolized by CYP 450 Enzymes: concomitant use with other drugs mainly metabolized by CYP3A4 that have a narrow therapeutic index (e.g., quinidine) should be used with caution and increased monitoring may be required ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Proton Pump Inhibitors, H2-receptor Antagonists, or Antacids: may decrease bioavailability of MYCAPSSA and the MYCAPSSA dose may need to be increased ( 7 ). (bula de Octreotida, Interações medicamentosas)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
- TelotristateModerada
Short-Acting Octreotide Concurrent administration of short-acting octreotide with Xermelo significantly decreased the systemic exposure of telotristat ethyl and telotristat, the active metabolite. (bula de Telotristate, Interações medicamentosas)
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)
Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (7.2) ]. (bula de Octreotida, Advertências e precauções)
Hypoglycemia or Hyperglycemia: Monitor glucose and adjust antidiabetic treatment as needed ( 5.2 ). (bula de Octreotida, Advertências e precauções)
Beta Blocker and Calcium Channel Blockers : dose adjustment of beta blockers or calcium channel blockers may be necessary ( 7 ). (bula de Octreotida, Interações medicamentosas)
Change in vitamin B12 levels: Monitor vitamin B 12 levels during treatment ( 5.6 ). (bula de Octreotida, Advertências e precauções)
Verifique Octreotida com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.
Abrir no verificadorNão é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.