Interaction Checker

Interações de Pazopanibe

Pazopanibe (Votrient) tem 257 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 148; moderadas: 107; leves: 2; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (148)

  • Abrocitinibeinibidor da JAKGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • AlfuzosinaalfabloqueadorGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • AmiodaronaantiarrítmicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Amitriptilinaantidepressivo tricíclicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Anagrelidamedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Antiácidos (Tums, Maalox, Mylanta)Produtos de venda livreGrave

    If concomitant administration with a gastric acid-reducing agent cannot be avoided, consider short-acting antacids in place of PPIs and H2-receptor antagonists. (bula de Pazopanibe, Interações medicamentosas)

  • Aprepitantoinibidor da CYP3A4Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Armodafinilaestimulante do SNCGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • AsenapinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • AtazanavirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Azitromicinaantibiótico macrolídeoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Bicarbonato de sódioantiácidoGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Bosentanaindutor da CYP3A4Grave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • CarbamazepinaanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • CenobamatoanticonvulsivanteGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Cetoconazolantifúngico azólicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • CiclosporinaimunossupressorGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Cimetidinabloqueador H2Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • CiprofloxacinofluoroquinolonaGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • CitalopramISRSGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Claritromicinaantibiótico macrolídeoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • ClobazambenzodiazepínicoGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • CloroquinaantimaláricoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • ClorpromazinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • ClozapinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • DarunavirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Darunavir + cobicistateantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Deferasiroxsuplemento de ferroGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Deutetrabenazinainibidor do VMAT2Grave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • DexametasonacorticosteroideGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Dexlansoprazolinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Dextrometorfano + quinidinamedicamento serotoninérgicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Diltiazembloqueador dos canais de cálcioGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • DisopiramidaantiarrítmicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • DofetilidaantiarrítmicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • DronedaronaantiarrítmicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Droperidolantagonista da dopaminaGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • EfavirenzantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Efavirenz + lamivudina + tenofovirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Elvitegravir + cobicistate + entricitabina + tenofovirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Eritromicinaantibiótico macrolídeoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • EscitalopramISRSGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • EslicarbazepinaanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Esomeprazolinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • EtravirinaantirretroviralGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • EverolimoimunossupressorGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Famotidinabloqueador H2Grave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • FenitoínaanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • FenobarbitalbarbitúricoGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Fentermina + topiramatoestimulante do SNCGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • FingolimodeimunossupressorGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • FlecainidaantiarrítmicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Flibanserinadepressor do SNCGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • Fluconazolantifúngico azólicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • FluoxetinaISRSGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • FosamprenavirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Fosaprepitantoinibidor da CYP3A4Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • FosfenitoínaanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Granisetronamedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • GriseofulvinaantifúngicoGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • HaloperidolantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Hidroxicloroquinamedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Hidroxizinaanti-histamínicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Ibuprofeno + famotidinaAINEGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • IbutilidaantiarrítmicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • IloperidonaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Imatinibeinibidor da CYP3A4Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • IsoniazidaantibióticoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Itraconazolantifúngico azólicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Ivacaftorinibidor da CYP3A4Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Lansoprazolinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Lapatinibeinibidor da glicoproteína PGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • Ledipasvir + sofosbuvirantiviralGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • LenacapavirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • LevofloxacinofluoroquinolonaGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Loperamidamedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Lopinavir + ritonavirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Lorlatinibeindutor da CYP3A4Grave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • MetadonaopioideGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Mifepristonainibidor da CYP3A4Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Mirabegronaagonista beta-adrenérgicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Mitapivateindutor da CYP3A4Grave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Mitotanoindutor da CYP3A4Grave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Modafinilaestimulante do SNCGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • MoxifloxacinofluoroquinolonaGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Nafcilinaantibiótico da classe das penicilinasGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Naproxeno + esomeprazolAINEGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • NefazodonaantidepressivoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • NevirapinaantirretroviralGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Nilotinibemedicamento que prolonga o intervalo QTGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • Nirmatrelvir + ritonavirantiviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Nizatidinabloqueador H2Grave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • OfloxacinofluoroquinolonaGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Omeprazolinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Omeprazol + bicarbonato de sódioinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Ondansetronamedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • OxcarbazepinaanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Palbociclibeinibidor da CYP3A4Grave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • PaliperidonaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Pantoprazolinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Pentamidinamedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • PerampanelanticonvulsivanteGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • PimavanserinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • PimozidaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Pitolisantomedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Posaconazolantifúngico azólicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • PrimidonaanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • ProcainamidaantiarrítmicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Prometazinaanti-histamínicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Prometazina + codeínaopioideGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Prometazina + dextrometorfanoanti-histamínicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • PropafenonaantiarrítmicoGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • QuetiapinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • QuinidinaantiarrítmicoGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • QuininaantimaláricoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Rabeprazolinibidor da bomba de prótonsGrave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Ranitidinabloqueador H2Grave

    Concomitant Use With Gastric Acid-Reducing Agents : Avoid concomitant use of VOTRIENT with gastric acid-reducing agents. (bula de Pazopanibe, Interações medicamentosas)

  • Ranolazinamedicamento que prolonga o intervalo QTGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • RifabutinaantibióticoGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • RifampicinaantibióticoGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • RifapentinaantibióticoGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • RisperidonaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • RitonavirantirretroviralGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Sofosbuvir + velpatasvirantiviralGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

  • SolifenacinaanticolinérgicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • SotalolbetabloqueadorGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Suvorexantosedativo-hipnóticoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Suzetriginaindutor da CYP3A4Grave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • TacrolimoimunossupressorGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Tamoxifenomodulador seletivo do receptor de estrogênioGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Tetrabenazinainibidor do VMAT2Grave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Ticagrelorantiagregante plaquetárioGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • TioridazinaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • TolterodinaanticolinérgicoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • TopiramatoanticonvulsivanteGrave

    VOTRIENT is not recommended if chronic use of strong CYP3A4 inducers cannot be avoided. (bula de Pazopanibe, Interações medicamentosas)

  • Toremifenomodulador seletivo do receptor de estrogênioGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • TramadolopioideGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Tramadol + paracetamolopioideGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • TrazodonaantidepressivoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Trióxido de arsêniomedicamento que prolonga o intervalo QTGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Valbenazinainibidor do VMAT2Grave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Vardenafilainibidor da PDE5Grave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • VenlafaxinaIRSNGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • Verapamilbloqueador dos canais de cálcioGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • Voriconazolantifúngico azólicoGrave

    Strong CYP3A4 Inhibitors : Avoid coadministration of VOTRIENT with strong CYP3A4 inhibitors. (bula de Pazopanibe, Interações medicamentosas)

  • ZiprasidonaantipsicóticoGrave

    Avoid coadministration of VOTRIENT with drugs known to prolong the QT/QTc interval. (bula de Pazopanibe, Interações medicamentosas)

  • ZonisamidaanticonvulsivanteGrave

    Avoid concomitant use of VOTRIENT with strong inhibitors of P-gp or BCRP. (bula de Pazopanibe, Interações medicamentosas)

Interações moderadas (107)

  • AcebutololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Ácido etacrínicodiurético de alçaModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • AdenosinaantiarrítmicoModerada

    Monitor patients who are at significant risk of developing QTc prolongation, including patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval, and those with relevant preexisting cardiac disease [see Drug Interactions (7.5)] . (bula de Pazopanibe, Advertências e precauções)

  • Alisquirenoanti-hipertensivoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Amiloridadiurético poupador de potássioModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Anlodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Anlodipino + atorvastatinabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Anlodipino + benazeprilbloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Anlodipino + olmesartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Anlodipino + valsartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • AtenololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Atenolol + clortalidonabetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • AtorvastatinaestatinaModerada

    Insufficient data are available to assess the risk of concomitant administration of alternative statins and VOTRIENT. (bula de Pazopanibe, Advertências e precauções)

  • Azilsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Benazeprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Benazepril + hidroclorotiazidainibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • BetaxololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • BisoprololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Bisoprolol + hidroclorotiazidabetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Candesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Captoprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • CarvedilolbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Clonidinaagonista alfa-adrenérgicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Clorotiazidadiurético tiazídicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Clortalidonadiurético tiazídicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Digoxinaglicosídeo digitálicoModerada

    Monitor patients who are at significant risk of developing QTc prolongation, including patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval, and those with relevant preexisting cardiac disease [see Drug Interactions (7.5)] . (bula de Pazopanibe, Advertências e precauções)

  • Dinitrato de isossorbida + hidralazinanitratoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • DoxazosinaalfabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Enalaprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Enalapril + hidroclorotiazidainibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Enalaprilateinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Eplerenonaantagonista da aldosteronaModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • EsmololbetabloqueadorModerada

    Monitor patients who are at significant risk of developing QTc prolongation, including patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval, and those with relevant preexisting cardiac disease [see Drug Interactions (7.5)] . (bula de Pazopanibe, Advertências e precauções)

  • Espironolactonaantagonista da aldosteronaModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Ezetimiba + sinvastatinaestatinaModerada

    Concomitant Use of Simvastatin Concomitant use of VOTRIENT and simvastatin increases the risk of ALT elevations [see Drug Interactions (7.3)] . (bula de Pazopanibe, Advertências e precauções)

  • Felodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • FenoxibenzaminaalfabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • FluvastatinaestatinaModerada

    Insufficient data are available to assess the risk of concomitant administration of alternative statins and VOTRIENT. (bula de Pazopanibe, Advertências e precauções)

  • Fosinoprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Fosinopril + hidroclorotiazidainibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Furosemidadiurético de alçaModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Guanfacinaagonista alfa-adrenérgicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • HidralazinavasodilatadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Indapamidadiurético tiazídicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Irbesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Isradipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • LabetalolbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Levotiroxinahormônio tireoidianoModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Levotiroxina + liotironinahormônio tireoidianoModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Lidocaínaanestésico localModerada

    Monitor patients who are at significant risk of developing QTc prolongation, including patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval, and those with relevant preexisting cardiac disease [see Drug Interactions (7.5)] . (bula de Pazopanibe, Advertências e precauções)

  • Lidocaína + prilocaínaanestésico localModerada

    Monitor patients who are at significant risk of developing QTc prolongation, including patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval, and those with relevant preexisting cardiac disease [see Drug Interactions (7.5)] . (bula de Pazopanibe, Advertências e precauções)

  • Liotironinahormônio tireoidianoModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Lisinoprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • LomitapidaModerada

    …Weak CYP3A4 inhibitors (such as alprazolam, amiodarone, amlodipine, atorvastatin, bicalutamide, cilostazol, cimetidine, cyclosporine, fluoxetine, fluvoxamine, ginkgo, goldenseal, isoniazid, lapatinib, nilotinib, pazopanib, ranitidine, ranolazine, ticagrelor, zileuton) can increase lomitapide exposure approximately 2-fold [see Clinical Pharmacology (12.3) ] . (bula de Lomitapida, Interações medicamentosas)

  • Losartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • LovastatinaestatinaModerada

    Insufficient data are available to assess the risk of concomitant administration of alternative statins and VOTRIENT. (bula de Pazopanibe, Advertências e precauções)

  • Mecamilaminaanti-hipertensivoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Metildopaanti-hipertensivoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Metolazonadiurético tiazídicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • MetoprololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • MexiletinaantiarrítmicoModerada

    Monitor patients who are at significant risk of developing QTc prolongation, including patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval, and those with relevant preexisting cardiac disease [see Drug Interactions (7.5)] . (bula de Pazopanibe, Advertências e precauções)

  • MinoxidilvasodilatadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Moexiprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • NadololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • NebivololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Nicardipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Nifedipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Nisoldipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Nitroprusseto de sódiovasodilatadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Olmesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • PemetrexedeantimetabólitoModerada

    Clinical trials of VOTRIENT in combination with pemetrexed and lapatinib were terminated early due to increased toxicity and mortality. (bula de Pazopanibe, Advertências e precauções)

  • Perindoprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • PindololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • PitavastatinaestatinaModerada

    Insufficient data are available to assess the risk of concomitant administration of alternative statins and VOTRIENT. (bula de Pazopanibe, Advertências e precauções)

  • PravastatinaestatinaModerada

    Insufficient data are available to assess the risk of concomitant administration of alternative statins and VOTRIENT. (bula de Pazopanibe, Advertências e precauções)

  • PrazosinaalfabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Propiltiouracilamedicamento antitireoidianoModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • PropranololbetabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Quinaprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Quinapril + hidroclorotiazidainibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Ramiprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • RosuvastatinaestatinaModerada

    Insufficient data are available to assess the risk of concomitant administration of alternative statins and VOTRIENT. (bula de Pazopanibe, Advertências e precauções)

  • Sacubitril + valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • SinvastatinaestatinaModerada

    Concomitant Use of Simvastatin Concomitant use of VOTRIENT and simvastatin increases the risk of ALT elevations [see Drug Interactions (7.3)] . (bula de Pazopanibe, Advertências e precauções)

  • Telmisartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Telmisartana + anlodipinobloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • TerazosinaalfabloqueadorModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Teriparatidahormônio tireoidianoModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Tiamazol (metimazol)medicamento antitireoidianoModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Tizanidinarelaxante muscularModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Trandolaprilinibidor da ECAModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Trianterenodiurético poupador de potássioModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

Menções leves (2)

  • BevacizumabeLeve

    Thrombotic Microangiopathy Thrombotic microangiopathy (TMA), including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), occurred in clinical trials of VOTRIENT as monotherapy, in combination with bevacizumab, and in combination with topotecan. (bula de Pazopanibe, Advertências e precauções)

  • TopotecanoLeve

    Thrombotic Microangiopathy Thrombotic microangiopathy (TMA), including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), occurred in clinical trials of VOTRIENT as monotherapy, in combination with bevacizumab, and in combination with topotecan. (bula de Pazopanibe, Advertências e precauções)

Verifique Pazopanibe com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.