Interações de Propiltiouracila

Propiltiouracila (PTU), medicamento antitireoidiano, tem 202 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 18; moderadas: 99; leves: 83; casos em que uma bula relata não haver interação significativa: 2). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (18)

  • Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid, adrenal, or pituitary disorders). (bula de Alfacoriogonadotropina, Contraindicações)

  • Brimonidina + timololagonista alfa-adrenérgicoGrave

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (bula de Brimonidina + timolol, Advertências e precauções)

  • Clomifenomodulador seletivo do receptor de estrogênioGrave

    Clomiphene citrate tablets are contraindicated in patients with uncontrolled thyroid or adrenal dysfunction or in the presence of an organic intracranial lesion such as pituitary tumor (see INDICATIONS AND USAGE). (bula de Clomifeno, Contraindicações)

  • DexametasonacorticosteroideGrave

    When concomitant administration of corticosteroids and levothyroxine is required, administration of corticosteroid should precede the initiation of levothyroxine therapy to avoid adrenal crisis. (bula de Dexametasona, Advertências e precauções)

  • Dorzolamida + timololinibidor da anidrase carbônicaGrave

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (bula de Dorzolamida + timolol, Advertências e precauções)

  • Dulaglutidaagonista do receptor de GLP-1Grave

    WARNING: RISK OF THYROID C-CELL TUMORS In male and female rats, dulaglutide causes a dose-related and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure. (bula de Dulaglutida, Advertência em caixa preta)

  • Reactions including anaphylaxis have been reported [see Adverse Reactions (6.2) ] High levels of FSH indicating primary gonadal failure Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid, adrenal, or pituitary disorders) [see Indications and Usage (1.1 , 1.2 , 1.3) ] Hypersensitivity reactions to streptomycin or neomycin. (bula de Folitropina, Contraindicações)

  • Lantânioquelante de fosfatoGrave

    Do not take thyroid hormone replacement therapy within 2 hours of dosing with LANTHANUM CARBONATE. (bula de Lantânio, Interações medicamentosas)

  • Liraglutidaagonista do receptor de GLP-1Grave

    WARNING: RISK OF THYROID C-CELL TUMORS • Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. (bula de Liraglutida, Advertência em caixa preta)

  • NadololbetabloqueadorGrave

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blockade which might precipitate a thyroid storm. (bula de Nadolol, Advertências)

  • PindololbetabloqueadorGrave

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-blockade which might precipitate a thyroid crisis. (bula de Pindolol, Advertências)

  • PropranololbetabloqueadorGrave

    Avoid abrupt withdrawal of beta-blockade, which may precipitate a thyroid storm. (bula de Propranolol, Advertências e precauções)

  • Semaglutidaagonista do receptor de GLP-1Grave

    WARNING: RISK OF THYROID C-CELL TUMORS • In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (bula de Semaglutida, Advertência em caixa preta)

  • SotalolbetabloqueadorGrave

    Thyroid Abnormalities Avoid abrupt withdrawal of beta-blockade which might be followed by an exacerbation of symptoms of hyperthyroidism, including thyroid storm. (bula de Sotalol, Advertências e precauções)

  • Tiamazol (metimazol)medicamento antitireoidianoGrave

    Propylthiouracil should be reserved for patients who cannot tolerate methimazole and in whom radioactive iodine therapy or surgery are not appropriate treatments for the management of hyperthyroidism. (bula de Propiltiouracila, Advertência em caixa preta)

  • TimololbetabloqueadorGrave

    Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (bula de Timolol, Advertências e precauções)

  • Tirzepatidaagonista do receptor de GLP-1Grave

    WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (bula de Tirzepatida, Advertência em caixa preta)

  • Tranilciprominainibidor da MAOGrave

    People who have thyroid problems (hyperthyroidism) may have a higher chance of having a hypertensive crisis. (bula de Tranilcipromina, Advertência em caixa preta)

Interações moderadas (99)

  • AcebutololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • AlendronatobisfosfonatoModerada

    Levothyroxine The bioavailability of alendronate was slightly decreased when BINOSTO and levothyroxine were co-administered to healthy subjects [see Clinical Pharmacology (12.3) ] . (bula de Alendronato, Interações medicamentosas)

  • Alogliptina + metforminainibidor da DPP-4Moderada

    Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs and isoniazid Alogliptin Cytochrome (CYP) P450, CYP-Substrates or Inhibitors Clinical Impact: Insulin Secretagogues and Insulin Insulin and insulin secretagogues… (bula de Alogliptina + metformina, Interações medicamentosas)

  • Alopurinolinibidor da xantina oxidaseModerada

    Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • AminofilinametilxantinaModerada

    Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Thyroid Abnormalities Nexterone inhibits peripheral conversion of throxine (T4) to triiodothyronine (T3) and may cause increased T3 levels, and increased levels of inactive reverse T3 (rT3) in clinically euthyroid patients. (bula de Amiodarona, Advertências e precauções)

  • ApixabanaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • ArgatrobanaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • AtenololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • Atenolol + clortalidonabetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • AxitinibeModerada

    Monitor thyroid function before initiation of, and periodically throughout, treatment with INLYTA. (bula de Axitinibe, Advertências e precauções)

  • Thyroid function should be monitored periodically. (bula de Betainterferona 1a, Advertências e precauções)

  • BetaxololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • BexarotenoretinoideModerada

    Monitor and replace thyroid hormone if needed. (bula de Bexaroteno, Advertências e precauções)

  • BisoprololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • Bisoprolol + hidroclorotiazidabetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • BivalirudinaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • CarvedilolbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • Colesevelamsequestrante de ácidos biliaresModerada

    Concomitant use with colesevelam hydrochloride may decrease the exposure of the following drugs: Drugs with a narrow therapeutic index (e.g., cyclosporine), phenytoin, thyroid hormone replacement therapy, warfarin, oral contraceptives containing ethinyl estradiol and norethindrone, olmesartan medoxomil, and sulfonylureas (glimepiride, glipizide, glyburide). (bula de Colesevelam, Interações medicamentosas)

  • Colestiraminasequestrante de ácidos biliaresModerada

    Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (bula de Colestiramina, Interações medicamentosas)

  • DabigatranaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • DanazolandrogênioModerada

    Other metabolic events include a reduction in thyroid binding globulin and T4 with increased uptake of T3, but without disturbance of thyroid stimulating hormone or of free thyroxin index. (bula de Danazol, Precauções)

  • DeflazacortecorticosteroideModerada

    In addition, patients with hypopituitarism, primary adrenal insufficiency or congenital adrenal hyperplasia, altered thyroid function, or pheochromocytoma may be at increased risk for adverse endocrine events. (bula de Deflazacorte, Advertências e precauções)

  • Desipraminaantidepressivo tricíclicoModerada

    In patients with thyroid disease or those taking thyroid medication, because of the possibility of cardiovascular toxicity, including arrhythmias. e. (bula de Desipramina, Advertências)

  • Desogestrel + etinilestradiolanticoncepcional oralModerada

    Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because serum concentrations of thyroid-binding globulin increases with use of COCs. (bula de Desogestrel + etinilestradiol, Interações medicamentosas)

  • Diacetato de etinodiol + etinilestradiolanticoncepcional oralModerada

    …and blood components may be affected by oral contraceptives: a) Increased prothrombin and factors VII, VIII, IX and X; decreased antithrombin III; increased platelet aggregability. b) Increased thyroid binding globulin (TBG), leading to increased circulating total thyroid hormone as measured by protein-bound iodine (PBI), T 4 by column or by radioimmunoassay. (bula de Diacetato de etinodiol + etinilestradiol, Precauções)

  • Digoxinaglicosídeo digitálicoModerada

    Digitalis glycosides: Serum digitalis levels may be increased when hyperthyroid patients on a stable digitalis glycoside regimen become euthyroid; a reduced dose of digitalis glycosides may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because serum concentrations of thyroid-binding globulin increase with use of COCs [see Drug Interactions ( 7.2 )] . (bula de Drospirenona + etinilestradiol, Advertências e precauções)

  • EdoxabanaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • EnoxaparinaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • Epinefrina (adrenalina)simpaticomiméticoModerada

    …[see Warnings and Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids… (bula de Epinefrina (adrenalina), Interações medicamentosas)

  • Ergotamina + cafeínaalcaloide do ergotModerada

    Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • EslicarbazepinaanticonvulsivanteModerada

    Abnormal Thyroid Function Tests Dose-dependent decreases in serum T3 and T4 (free and total) values have been observed in patients taking APTIOM. (bula de Eslicarbazepina, Advertências e precauções)

  • EsmololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • EstradiolestrogênioModerada

    Hypothyroidism Estrogen administration leads to increased thyroid-binding globulin (TBG) levels. (bula de Estradiol, Precauções)

  • Estradiol + dienogesteanticoncepcional oralModerada

    Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because serum concentrations of thyroid-binding globulin increase with use of COCs [see Clinical Pharmacology ( 12.3 )] . (bula de Estradiol + dienogeste, Advertências e precauções)

  • Estradiol + noretisteronaestrogênioModerada

    Discontinue estrogen if severe hypercalcemia, loss of vision, severe hypertriglyceridemia or cholestatic jaundice occurs ( 5.5 , 5.6 , 5.9 , 5.10 ) Monitor thyroid function in women on thyroid replacement therapy ( 5.11 , 5.18 ) (bula de Estradiol + noretisterona, Advertências e precauções)

  • Estrogênios conjugadosestrogênioModerada

    Hypothyroidism Estrogen administration leads to increased thyroid-binding globulin (TBG) levels. (bula de Estrogênios conjugados, Precauções)

  • • Monitor thyroid function in women on thyroid replacement therapy ( 5.10 , 5.17 ) (bula de Estrogênios conjugados + bazedoxifeno, Advertências e precauções)

  • The dose of replacement thyroid hormones or cortisol therapy may need to be increased. (bula de Etonogestrel + etinilestradiol, Advertências e precauções)

  • Febuxostateinibidor da xantina oxidaseModerada

    Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • Fitomenadiona (vitamina K1)vitamina KModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • FondaparinuxanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • Furosemidadiurético de alçaModerada

    Thyroid hormones High-doses (> 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels. (bula de Furosemida, Interações medicamentosas)

  • GlimepiridasulfonilureiaModerada

    …somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline), and isoniazid. (bula de Glimepirida, Interações medicamentosas)

  • GlipizidasulfonilureiaModerada

    …olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), thyroid hormones, phenytoin, nicotinic acid, and calcium channel blocking drugs. (bula de Glipizida, Interações medicamentosas)

  • HeparinaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • …recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (bula de Hialuronidase, Interações medicamentosas)

  • Imipraminaantidepressivo tricíclicoModerada

    …levels of the drug; Patients with history of urinary retention, or history of narrow-angle glaucoma because of the drug's anticholinergic properties; hyperthyroid patients or those on thyroid medication because of the possibility of cardiovascular toxicity; patients with a history of seizure disorder because this drug has been shown to lower the seizure threshold;… (bula de Imipramina, Advertências)

  • Insulina asparteinsulinaModerada

    …Insulin Aspart Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. (bula de Insulina asparte, Interações medicamentosas)

  • Insulina degludecainsulinaModerada

    …Insulin Degludec Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. (bula de Insulina degludeca, Interações medicamentosas)

  • Insulina detemirinsulinaModerada

    …Effect of LEVEMIR Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. (bula de Insulina detemir, Interações medicamentosas)

  • Insulina glarginainsulinaModerada

    …Glargine-yfgn Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. (bula de Insulina glargina, Interações medicamentosas)

  • Insulina lisproinsulinaModerada

    …Effect of LYUMJEV Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. (bula de Insulina lispro, Interações medicamentosas)

  • Drug Interactions: Concurrent use with lithium or antithyroid drugs may potentiate the hypothyroid and goitrogenic effects of these medications. (bula de Iodeto de potássio, Interações medicamentosas)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoModerada

    Drugs that may potentiate clinical response of Isoproterenol Clinical Impact The effects of isoproterenol may be potentiated by tricyclic antidepressants, monoamine oxidase inhibitors, levothyroxine sodium, and certain antihistamines, notably chlorpheniramine, tripelennamine, and diphenhydramine. (bula de Isoprenalina (isoproterenol), Interações medicamentosas)

  • LabetalolbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • LanreotidaModerada

    Thyroid Function Abnormalities : Decreases in thyroid function may occur; perform tests where clinically indicated. (bula de Lanreotida, Advertências e precauções)

  • Levonorgestrel + etinilestradiolanticoncepcional oralModerada

    The dose of replacement thyroid hormone or cortisol therapy may need to be increased. (bula de Levonorgestrel + etinilestradiol, Advertências e precauções)

  • Lítiomedicamento serotoninérgicoModerada

    • Hypothyroidism and Hyperthyroidism: Monitor thyroid function regularly ( 5.7 ). (bula de Lítio, Advertências e precauções)

  • MetoprololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • Midodrinaagonista alfa-adrenérgicoModerada

    The risk of hypertension increases with concomitant administration of drugs that increase blood pressure (phenylephrine, pseudoephedrine, ephedrine, dihydroergotamine, thyroid hormones, or droxidopa). (bula de Midodrina, Interações medicamentosas)

  • NateglinidameglitinidaModerada

    Drugs and Herbals That May Reduce the Blood-Glucose-Lowering Effect of Nateglinide and Increase Susceptibility to Hyperglycemia Drugs: Thiazides, corticosteroids, thyroid products, sympathomimetics, somatropin, somatostatin analogues (e.g., lanreotide, octreotide), and CYP inducers (e.g., rifampin, phenytoin and St John's Wort). (bula de Nateglinida, Interações medicamentosas)

  • NebivololbetabloqueadorModerada

    Beta-adrenergic blocking agents: Hyperthyroidism may cause an increased clearance of beta blockers with a high extraction ratio. (bula de Propiltiouracila, Interações medicamentosas)

  • The dose of replacement thyroid hormone or cortisol therapy may need to be increased. (bula de Norelgestromina + etinilestradiol, Advertências e precauções)

  • NoretisteronaprogestinaModerada

    • Thyroxine concentrations may be decreased, due to a decrease in thyroid binding globulin (TBG). (bula de Noretisterona, Precauções)

  • Noretisterona + etinilestradiolanticoncepcional oralModerada

    Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because serum concentrations of thyroid binding globulin increase with use of COCs. (bula de Noretisterona + etinilestradiol, Advertências e precauções)

  • Norgestimato + etinilestradiolanticoncepcional oralModerada

    The dose of replacement thyroid hormone or cortisol therapy may need to be increased. (bula de Norgestimato + etinilestradiol, Advertências e precauções)

  • Norgestrel + etinilestradiolanticoncepcional oralModerada

    Women on thyroid hormone replacement therapy may need increased doses of thyroid hormone because serum concentration of thyroid-binding globulin increases with use of COCs. (bula de Norgestrel + etinilestradiol, Interações medicamentosas)

  • OctreotidaModerada

    Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (bula de Octreotida, Advertências e precauções)

  • Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • OrlistateModerada

    Drug Interactions and Decreased Vitamin Absorption ORLISTAT may interact with concomitant drugs including cyclosporine, levothyroxine, warfarin, amiodarone, antiepileptic drugs, and antiretroviral drugs [see Drug Interactions (7) ]. (bula de Orlistate, Advertências e precauções)

  • PasireotidaModerada

    Monitoring pituitary function (e.g., thyroid, adrenal, gonadal) prior to initiation of therapy with SIGNIFOR LAR, as well as periodically during treatment, as clinically appropriate, is recommended. (bula de Pasireotida, Advertências e precauções)

  • PazopanibeModerada

    Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • PentoxifilinametilxantinaModerada

    Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • Pioglitazona + glimepiridatiazolidinedionaModerada

    …somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline), and isoniazid. (bula de Pioglitazona + glimepirida, Interações medicamentosas)

  • PrednisolonacorticosteroideModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisolona, Advertências e precauções)

  • PrednisonacorticosteroideModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Prednisona, Advertências e precauções)

  • ProgesteronaprogestinaModerada

    Thyroid function: increase in PBI, and butanol extractable protein bound iodine and decrease in T3 uptake values. (bula de Progesterona, Interações medicamentosas)

  • PseudoefedrinadescongestionanteModerada

    Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland When using this product do not exceed recommended dosage Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur symptoms do not improve within 7 days or occur with a fever If pregnant or breast-feeding,… (bula de Pseudoefedrina, Advertências)

  • QuetiapinaantipsicóticoModerada

    Hypothyroidism Adults: Clinical trials with quetiapine demonstrated dose-related decreases in thyroid hormone levels. (bula de Quetiapina, Advertências e precauções)

  • RifampicinaantibióticoModerada

    Substitute non-enzyme inducing therapies at least 2 weeks prior to initiation of irinotecan therapy Decrease irinotecan and active metabolite exposure Levothyroxine Decrease exposure Losartan Parent Decrease AUC by 30% Active metabolite (E3174) Decrease AUC by 40% Methadone In patients well-stabilized on methadone, concomitant administration of rifampin resulted… (bula de Rifampicina, Interações medicamentosas)

  • RifapentinaantibióticoModerada

    …levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines Theophylline Narcotic analgesics Methadone Phosphodiesterase-5 (PDE-5) Inhibitors Sildenafil Thyroid preparations Levothyroxine Tricyclic antidepressants Amitriptyline, nortriptyline 7.5 Other Interactions The conversion of PRIFTIN to 25-desacetyl rifapentine is mediated by an esterase enzyme. (bula de Rifapentina, Interações medicamentosas)

  • RivaroxabanaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • Sevelâmerquelante de fosfatoModerada

    For oral medication where a reduction in the bioavailability of that medication would have a clinically significant effect on its safety or efficacy (e.g., cyclosporine, tacrolimus, levothyroxine), consider separation of the timing of the administration of the two drugs [see Clinical Pharmacology (12.3) ] . (bula de Sevelâmer, Interações medicamentosas)

  • SomatropinaModerada

    Hypothyroidism: Monitor thyroid function periodically as hypothyroidism may occur or worsen after initiation of somatropin. (bula de Somatropina, Advertências e precauções)

  • SorafenibeModerada

    • Impairment of Thyroid Stimulating Hormone Suppression (TSH) in DTC : Monitor TSH monthly and adjust thyroid replacement therapy in patients with thyroid cancer. (bula de Sorafenibe, Advertências e precauções)

  • SunitinibeModerada

    • Thyroid Dysfunction : Monitor thyroid function at baseline, periodically during treatment, and as clinically indicated. (bula de Sunitinibe, Advertências e precauções)

  • Tamoxifenomodulador seletivo do receptor de estrogênioModerada

    Drug-Laboratory Test Interactions There are postmarketing reports of T 4 elevations in postmenopausal patients taking tamoxifen that may be explained by increases in thyroid-binding globulin. (bula de Tamoxifeno, Interações medicamentosas)

  • TeofilinametilxantinaModerada

    Theophylline: Theophylline clearance may decrease when hyperthyroid patients on a stable theophylline regimen become euthyroid; a reduced dose of theophylline may be needed. (bula de Propiltiouracila, Interações medicamentosas)

  • TriancinolonacorticosteroideModerada

    Changes in thyroid status of the patient may necessitate adjustment in dosage. (bula de Triancinolona, Advertências)

  • Trimipraminaantidepressivo tricíclicoModerada

    Caution is advised in patients with history of urinary retention because of the drug's anticholinergic properties; hyperthyroid patients or those on thyroid medication because of the possibility of cardiovascular toxicity; patients with a history of seizure disorder, because this drug has been shown to lower the seizure threshold; patients receiving guanethidine… (bula de Trimipramina, Advertências)

  • VarfarinaanticoagulanteModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

  • Vitamina KVitaminas e mineraisModerada

    Drug Interactions Anticoagulants (oral) : Due to the potential inhibition of vitamin K activity by propylthiouracil, the activity of oral anticoagulants (e.g., warfarin) may be increased; additional monitoring of PT/INR should be considered, especially before surgical procedures. (bula de Propiltiouracila, Interações medicamentosas)

Menções leves (83)

  • AbatacepteimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Abrocitinibeinibidor da JAKLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • AcarboseantidiabéticoLeve

    These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel-blocking drugs, and isoniazid. (bula de Acarbose, Interações medicamentosas)

  • Ácido valproicoanticonvulsivanteLeve

    Effect on Ketone and Thyroid Function Tests Valproate is partially eliminated in the urine as a keto-metabolite which may lead to a false interpretation of the urine ketone test. (bula de Ácido valproico, Advertências e precauções)

  • Ácido zoledrônicobisfosfonatoLeve

    Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (bula de Ácido zoledrônico, Advertências e precauções)

  • AdalimumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • AlentuzumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Amitriptilinaantidepressivo tricíclicoLeve

    Guanethidine or similarly acting compounds; thyroid medication; alcohol, barbiturates and other CNS depressants; and disulfiram – see WARNINGS section. (bula de Amitriptilina, Interações medicamentosas)

  • AzatioprinaimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Azelastina + fluticasonaanti-histamínicoLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Baricitinibeinibidor da JAKLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • BeclometasonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • BetametasonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • BudesonidacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Budesonida + formoterolcorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (bula de Bussulfano, Advertências)

  • CarbamazepinaanticonvulsivanteLeve

    …dicumarol, dihydropyridine calcium channel blockers (e.g., felodipine), doxycycline, ethosuximide, everolimus, felbamate, glucocorticoids, haloperidol, imatinib, itraconazole, lamotrigine, levothyroxine, lorazepam, methadone, methsuxamide, mianserin, midazolam, mirtazapine, nefazodone, olanzapine, oral and other hormonal contraceptives, oxcarbazepine, paliperidone, phenytoin,… (bula de Carbamazepina, Interações medicamentosas)

  • CiclesonidacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • CiclofosfamidaimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • CiclosporinaimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Losartan, glipizide and levothyroxine did not show any changes in exposure when co-administered with LOKELMA. (bula de Ciclossilicato de zircônio sódico, Interações medicamentosas)

  • Other Medications Used for the Management of Fanconi Syndrome PROCYSBI can be administered with other electrolyte and mineral replacements necessary for management of Fanconi syndrome, as well as vitamin D and thyroid hormone. (bula de Cisteamina, Interações medicamentosas)

  • CladribinaantimetabólitoLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • ClobetasolcorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Dapagliflozina + metforminainibidor do SGLT2Leve

    These medications include thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (bula de Dapagliflozina + metformina, Interações medicamentosas)

  • DesonidacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Effect on Ketone and Thyroid Function Tests Valproate is partially eliminated in the urine as a keto-metabolite which may lead to a false interpretation of the urine ketone test. (bula de Divalproato de sódio (valproato), Advertências e precauções)

  • Empagliflozina + metforminainibidor do SGLT2Leve

    These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (bula de Empagliflozina + metformina, Interações medicamentosas)

  • EtanercepteimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • EverolimoimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • FingolimodeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • FludrocortisonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • FlunisolidacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • FluocinonidacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • FluticasonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Fluticasona + salmeterolcorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Fumarato de dimetilaimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • GlibenclamidasulfonilureiaLeve

    These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (bula de Glibenclamida, Interações medicamentosas)

  • Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (bula de Glibenclamida + metformina, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaLeve

    These drugs include thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (bula de Glipizida + metformina, Precauções)

  • GuselcumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • HalobetasolcorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • HidrocortisonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Cases of myelodysplastic syndrome, acute leukemias, lymphomas, thyroid cancers, and sarcomas have occurred and may develop several years after chemotherapy has been discontinued. (bula de Ifosfamida, Advertências e precauções)

  • Imatinibeinibidor da CYP3A4Leve

    Hypothyroidism has been reported in thyroidectomy patients undergoing levothyroxine replacement. (bula de Imatinibe, Advertências e precauções)

  • InfliximabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Atypical Antipsychotics (e.g., olanzapine and clozapine), Corticosteroids, Danazol, Diuretics, Estrogens, Glucagon, Isoniazid, Niacin, Oral Contraceptives, Phenothiazines, Progestogens (e.g., in oral contraceptives), Protease inhibitors, Somatropin, Sympathomimetic Agents (e.g., albuterol, epinephrine, terbutaline) and Thyroid Hormones. (bula de Insulina regular (humana), Interações medicamentosas)

  • LeflunomidaimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Thyroid Disorders Both hypothyroidism and hyperthyroidism have been reported [see Adverse Reactions (6.2) ] . (bula de Lenalidomida, Advertências e precauções)

  • Linagliptina + metforminainibidor da DPP-4Leve

    These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (bula de Linagliptina + metformina, Interações medicamentosas)

  • MercaptopurinaantimetabólitoLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • MetforminabiguanidaLeve

    Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (bula de Metformina, Interações medicamentosas)

  • MetilprednisolonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • MetiltestosteronaandrogênioLeve

    Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction. (bula de Metiltestosterona, Precauções)

  • Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (bula de Metirapona, Interações medicamentosas)

  • MetotrexatoimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • MicofenolatoimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Minociclinaantibiótico da classe das tetraciclinasLeve

    EMROSI may induce hyperpigmentation in many organs, including nails, bone, skin, eyes, thyroid, visceral tissue, oral cavity (teeth, mucosa, alveolar bone), sclerae and heart valves. (bula de Minociclina, Advertências e precauções)

  • Mitotanoindutor da CYP3A4Leve

    In cases of cognitive dysfunction, thyroid function should be evaluated as mitotane may induce hypothyroidism. (bula de Mitotano, Advertências e precauções)

  • MometasonacorticosteroideLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • NatalizumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Nortriptilinaantidepressivo tricíclicoLeve

    Great care is required if Pamelor is given to hyperthyroid patients or to those receiving thyroid medication, since cardiac arrhythmias may develop. (bula de Nortriptilina, Advertências)

  • OcrelizumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Olopatadina + mometasonaanti-histamínicoLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Pilocarpinaagonista colinérgicoLeve

    …performed, the following concomitant drugs were used in at least 10% of patients in either or both Sjogren's efficacy studies: acetylsalicylic acid, artificial tears, calcium, conjugated estrogens, hydroxychloroquine sulfate, ibuprofen, levothyroxine sodium, medroxyprogesterone acetate, methotrexate, multivitamins, naproxen, omeprazole, paracetamol, and prednisone. (bula de Pilocarpina, Interações medicamentosas)

  • Pimecrolimoinibidor da calcineurinaLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Pioglitazona + metforminatiazolidinedionaLeve

    These drugs include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (bula de Pioglitazona + metformina, Interações medicamentosas)

  • PonesimodeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Protriptilinaantidepressivo tricíclicoLeve

    On rare occasions, hyperthyroid patients or those receiving thyroid medication may develop arrhythmias when this drug is given. (bula de Protriptilina, Advertências)

  • RepaglinidameglitinidaLeve

    …antipsychotics (e.g., olanzapine and clozapine), calcium channel antagonists, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. (bula de Repaglinida, Interações medicamentosas)

  • Ritlecitinibeinibidor da JAKLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • RituximabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Saxagliptina + metforminainibidor da DPP-4Leve

    These medications include the thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blocking drugs, and isoniazid. (bula de Saxagliptina + metformina, Interações medicamentosas)

  • SecuquinumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • SirolimoimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • Sitagliptina + metforminainibidor da DPP-4Leve

    Examples: Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, and isoniazid. (bula de Sitagliptina + metformina, Interações medicamentosas)

  • TacrolimoimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • TeriflunomidaimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • TestosteronaandrogênioLeve

    Free thyroid hormone concentrations remain unchanged, however, and there is no clinical evidence of thyroid dysfunction. (bula de Testosterona, Advertências e precauções)

  • TocilizumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • TofacitinibeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • UpadacitinibeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

  • UstequinumabeimunossupressorLeve

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (bula de Propiltiouracila, Advertências)

Nenhuma interação significativa relatada (2)

  • FenoprofenoAINESem interação

    Thyroid-stimulating hormone, total thyroxine, and thyrotropin-releasing hormone response are not affected. (bula de Fenoprofeno, Interações medicamentosas)

  • Montelucasteantagonista do receptor de leucotrienosSem interação

    …adjustment is needed when SINGULAIR is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, fexofenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 (CYP) enzyme inducers [see Clinical Pharmacology (12.3)… (bula de Montelucaste, Interações medicamentosas)

Verifique Propiltiouracila com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.