Interações de Salsalato

Salsalato, AINE, tem 303 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 47; moderadas: 216; leves: 40; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (47)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • ApixabanaanticoagulanteGrave

    …risk of developing epidural or spinal hematomas in these patients include: • use of indwelling epidural catheters • concomitant use of other drugs that affect hemostasis, such as nonsteroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants • a history of traumatic or repeated epidural or spinal punctures • a history of spinal deformity… (bula de Apixabana, Advertência em caixa preta)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • CelecoxibeAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • CetoprofenoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • CetorolacoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • CidofovirantiviralGrave

    Nephrotoxic agents Concomitant administration of cidofovir injection and agents with nephrotoxic potential [e.g., intravenous aminoglycosides (e.g., tobramycin, gentamicin, and amikacin), amphotericin B, foscarnet, intravenous pentamidine, vancomycin, and nonsteroidal anti-inflammatory agents] is contraindicated. (bula de Cidofovir, Interações medicamentosas)

  • DabigatranaanticoagulanteGrave

    …the risk of developing epidural or spinal hematomas in these patients include: use of indwelling epidural catheters concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants a history of traumatic or repeated epidural or spinal punctures a history of spinal deformity… (bula de Dabigatrana, Advertência em caixa preta)

  • DiclofenacoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • DiflunisalAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • EdoxabanaanticoagulanteGrave

    …the risk of developing epidural or spinal hematomas in these patients include: use of indwelling epidural catheters concomitant use of other drugs that affect hemostasis, such as nonsteroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants a history of traumatic or repeated epidural or spinal punctures a history of spinal deformity… (bula de Edoxabana, Advertência em caixa preta)

  • Avoid SYMFI with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple non-steroidal anti-inflammatory drugs [NSAIDs]) [see Drug Interactions (7.3) ] . (bula de Efavirenz + lamivudina + tenofovir, Advertências e precauções)

  • EnoxaparinaanticoagulanteGrave

    …the risk of developing epidural or spinal hematomas in these patients include: Use of indwelling epidural catheters Concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, and other anticoagulants A history of traumatic or repeated epidural or spinal punctures A history of spinal deformity… (bula de Enoxaparina, Advertência em caixa preta)

  • COMPLERA should be avoided with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple nonsteroidal anti-inflammatory drugs [NSAIDs]) [see Drug Interactions (7.4) ]. (bula de Entricitabina + rilpivirina + tenofovir, Advertências e precauções)

  • EtodolacoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • FenoprofenoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Fisostigminainibidor da colinesteraseGrave

    Contraindications: ANTICHOLIUM ® should not be used in the presence of hypersensitivity to physostigmine salicylate, bronchial asthma, ulcers associated with tissue destruction (gangrene), coronary heart disease, constipation (mechanical obstipation), mechanical ischuria (urinary retention), hereditary form of muscle atrophy (myotonic dystrophy), closed traumatic… (bula de Fisostigmina, Contraindicações)

  • FlurbiprofenoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • FondaparinuxanticoagulanteGrave

    …risk of developing epidural or spinal hematomas in these patients include: • use of indwelling epidural catheters • concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, or other anticoagulants • a history of traumatic or repeated epidural or spinal puncture • a history of spinal deformity… (bula de Fondaparinux, Advertência em caixa preta)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • IbuprofenoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • IndometacinaAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • MeloxicamAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • MetotrexatoimunossupressorGrave

    Unexpectedly severe and fatal gastrointestinal toxicity can occur with concomitant administration of XATMEP (primarily at high dosage) and nonsteroidal anti-inflammatory drugs (NSAIDs) [see Drug Interactions ( 7.1 )] . (bula de Metotrexato, Advertências e precauções)

  • Misoprostolanálogo de prostaglandinaGrave

    MISOPROSTOL SHOULD NOT BE TAKEN BY PREGNANT WOMEN TO REDUCE THE RISK OF ULCERS INDUCED BY NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) (see CONTRAINDICATIONS , WARNINGS , and PRECAUTIONS ). (bula de Misoprostol, Advertência em caixa preta)

  • Montelucasteantagonista do receptor de leucotrienosGrave

    Patients with known aspirin sensitivity should continue to avoid aspirin or non-steroidal anti-inflammatory agents while taking SINGULAIR ( 5.4 ). (bula de Montelucaste, Advertências e precauções)

  • NabumetonaAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • NaproxenoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • OxaprozinaAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • PiroxicamAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • PralatrexatoantimetabólitoGrave

    Avoid coadministration with probenecid or nonsteroidal anti-inflammatory drugs. (bula de Pralatrexato, Interações medicamentosas)

  • Prasugrelantiagregante plaquetárioGrave

    Additional risk factors for bleeding include: body weight <60 kg, propensity to bleed, concomitant use of medications that increase the risk of bleeding (e.g . , warfarin, heparin, fibrinolytic therapy, chronic use of nonsteroidal anti-inflammatory drugs [NSAIDs]) [see Warnings and Precautions (5.1) ] . (bula de Prasugrel, Advertência em caixa preta)

  • In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (bula de Probenecida, Advertências)

  • In patients on probenecid and colchicine the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (bula de Probenecida + colchicina, Advertências)

  • RivaroxabanaanticoagulanteGrave

    …risk of developing epidural or spinal hematomas in these patients include: • use of indwelling epidural catheters • concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants • a history of traumatic or repeated epidural or spinal punctures • a history of spinal deformity… (bula de Rivaroxabana, Advertência em caixa preta)

  • SulindacoAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

  • TenofovirantirretroviralGrave

    VIREAD should be avoided with concurrent or recent use of a nephrotoxic agent (e.g., high-dose or multiple non-steroidal anti-inflammatory drugs [NSAIDs]) [see Drug Interactions (7.1) ] . (bula de Tenofovir, Advertências e precauções)

  • TolmetinaAINEGrave

    Salsalate tablets, USP should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. (bula de Salsalato, Contraindicações)

Interações moderadas (216)

  • AcarboseantidiabéticoModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Acetazolamidainibidor da anidrase carbônicaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Ácido etacrínicodiurético de alçaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Ácido zoledrônicobisfosfonatoModerada

    Nephrotoxic Drugs Caution is indicated when Reclast is used with other potentially nephrotoxic drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Ácido zoledrônico, Interações medicamentosas)

  • AdapalenoretinoideModerada

    Particular caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid in combination with Adapalene Cream, 0.1%. (bula de Adapaleno, Interações medicamentosas)

  • AdefovirantiviralModerada

    However, this is of special importance in patients at risk of or having underlying renal dysfunction and patients taking concomitant nephrotoxic agents such as cyclosporine, tacrolimus, aminoglycosides, vancomycin and non-steroidal anti-inflammatory drugs [See Adverse Reactions (6.2) and Clinical Pharmacology (12.3) ]. (bula de Adefovir, Advertências e precauções)

  • AfatinibeModerada

    Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (bula de Afatinibe, Advertências e precauções)

  • ÁlcoolÁlcoolModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • AlendronatobisfosfonatoModerada

    Use caution when co-prescribing aspirin/nonsteroidal anti- inflammatory drugs that may worsen gastrointestinal irritation. (bula de Alendronato, Interações medicamentosas)

  • Alisquirenoanti-hipertensivoModerada

    …part on the activity of the RAAS (e.g., patients with renal artery stenosis, severe heart failure, post-myocardial infarction or volume depletion) or patients receiving ARB, ACEI or nonsteroidal anti-inflammatory drug (NSAID), including selective Cyclooxygenase-2 inhibitors (COX-2 inhibitors), therapy may be at particular risk for developing acute renal failure… (bula de Alisquireno, Advertências e precauções)

  • Alogliptinainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Alogliptina + metforminainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Alprostadilanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • Amiloridadiurético poupador de potássioModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Amoxicilinaantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Amoxicilina + clavulanato de potássioantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Ampicilinaantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Ampicilina + sulbactamantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Anagrelidamedicamento que prolonga o intervalo QTModerada

    Monitor patients for bleeding, including those receiving concomitant therapy with other drugs known to cause bleeding (e.g., anticoagulants, PDE3 inhibitors, NSAIDs, antiplatelet agents, selective serotonin reuptake inhibitors) [see Drug Interactions (7.3) , Clinical Pharmacology (12.3) ] . (bula de Anagrelida, Advertências e precauções)

  • Anlodipino + benazeprilbloqueador dos canais de cálcio di-hidropiridínicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Anlodipino + olmesartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    • Increased exposure of amlodipine when coadministered with CYP3A inhibitors Olmesartan medoxomil ( 7.2 ): • Nonsteroidal anti-inflammatory drugs (NSAIDS) may lead to increased risk of renal impairment and loss of antihypertensive effect. (bula de Anlodipino + olmesartana, Interações medicamentosas)

  • Anlodipino + valsartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Non-Steroidal Anti-Inflammatory Agents Including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) : In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with angiotensin II receptor antagonists, including valsartan, may… (bula de Anlodipino + valsartana, Interações medicamentosas)

  • ArgatrobanaanticoagulanteModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Atenolol + clortalidonabetabloqueadorModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Azelastina + fluticasonaanti-histamínicoModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Azilsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Non-steroidal Anti-Inflammatory Agents, including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) In patients who are elderly, volume-depleted (including those on diuretic therapy), or who have compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with angiotensin II receptor antagonists, including azilsartan,… (bula de Azilsartana, Interações medicamentosas)

  • BalsalazidasalicilatoModerada

    ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (bula de Salsalato, Interações medicamentosas)

  • BeclometasonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Benazeprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Benazepril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • BetametasonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Bexagliflozinainibidor do SGLT2Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Bimatoprostaanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • Bisoprolol + hidroclorotiazidabetabloqueadorModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • BivalirudinaanticoagulanteModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Brinzolamidainibidor da anidrase carbônicaModerada

    • Rare instances of acid-base alterations have occurred with high-dose salicylate therapy. (bula de Brinzolamida, Interações medicamentosas)

  • Bromocriptinaagonista da dopaminaModerada

    Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects. (bula de Bromocriptina, Interações medicamentosas)

  • BudesonidacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Budesonida + formoterolcorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Bumetanidadiurético de alçaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Canagliflozinainibidor do SGLT2Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Candesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    NSAIDS use may lead to increased risk of renal impairment and loss of antihypertensive effect ( 7 ). (bula de Candesartana, Interações medicamentosas)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Captoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Carboprostaanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • CefotaximacefalosporinaModerada

    Drug Interactions As with other cephalosporins, cefotaxime may potentiate the nephrotoxic effects of nephrotoxic drugs such as aminoglycosides, NSAIDs and furosemide. (bula de Cefotaxima, Interações medicamentosas)

  • CiclesonidacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • CiclosporinaimunossupressorModerada

    In addition, concomitant use of NSAIDs with cyclosporine, particularly in the setting of dehydration, may potentiate renal dysfunction. (bula de Ciclosporina, Interações medicamentosas)

  • CiprofloxacinofluoroquinolonaModerada

    NSAIDs Use with caution Non-steroidal anti-inflammatory drugs (but not acetyl salicylic acid) in combination of very high doses of quinolones have been shown to provoke convulsions in pre-clinical studies and in postmarketing. (bula de Ciprofloxacino, Interações medicamentosas)

  • CitalopramISRSModerada

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk. (bula de Citalopram, Advertências e precauções)

  • Citrato de potássiosuplemento de potássioModerada

    Nonsteroidal Anti-inflammatory drugs (NSAIDs) monitor for hyperkalemia (7.4) (bula de Citrato de potássio, Interações medicamentosas)

  • ClobetasolcorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Clopidogrelantiagregante plaquetárioModerada

    Risk factors for bleeding include concomitant use of other drugs that increase the risk of bleeding (e.g., anticoagulants, antiplatelet agents, and chronic use of NSAIDs) [see Drug Interactions (7.4 , 7.5 , 7.6 , 7.7) ]. (bula de Clopidogrel, Advertências e precauções)

  • Cloreto de potássiosuplemento de potássioModerada

    Nonsteroidal anti-inflammatory drugs: Monitor for hyperkalemia ( 7.3 ) (bula de Cloreto de potássio, Interações medicamentosas)

  • Clorotiazidadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Clortalidonadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Dapagliflozinainibidor do SGLT2Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Dapagliflozina + metforminainibidor do SGLT2Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Deferasiroxsuplemento de ferroModerada

    The risk of GI hemorrhage may be increased when administering Exjade in combination with drugs that have ulcerogenic or hemorrhagic potential, such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, oral bisphosphonates, or anticoagulants. (bula de Deferasirox, Advertências e precauções)

  • DeflazacortecorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (bula de Desmopressina, Interações medicamentosas)

  • Desogestrel + etinilestradiolanticoncepcional oralModerada

    COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (bula de Desogestrel + etinilestradiol, Interações medicamentosas)

  • DesonidacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • DesvenlafaxinaIRSNModerada

    • Increased Risk of Bleeding: Concomitant use of aspirin, NSAIDs, other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.4 ). (bula de Desvenlafaxina, Advertências e precauções)

  • DexametasonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Diclorfenamidainibidor da anidrase carbônicaModerada

    Concomitant Use of Aspirin or Other Salicylates Carbonic anhydrase inhibitors, including KEVEYIS, can cause metabolic acidosis [see Warnings and Precautions (5.4) ] , which can increase the risk of salicylate toxicity. (bula de Diclorfenamida, Advertências e precauções)

  • Dicloxacilinaantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Dinoprostonaanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • Donepezilainibidor da colinesteraseModerada

    Therefore, patients should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Donepezila, Advertências e precauções)

  • Dorzolamidainibidor da anidrase carbônicaModerada

    High-Dose Salicylate Therapy Although acid-base and electrolyte disturbances were not reported in the clinical trials with dorzolamide hydrochloride ophthalmic solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associated with high-dose salicylate therapy). (bula de Dorzolamida, Interações medicamentosas)

  • Dorzolamida + timololinibidor da anidrase carbônicaModerada

    High-Dose Salicylate Therapy Although acid-base and electrolyte disturbances were not reported in the clinical trials with dorzolamide hydrochloride ophthalmic solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associated with high-dose salicylate therapy). (bula de Dorzolamida + timolol, Interações medicamentosas)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (bula de Drospirenona + etinilestradiol, Advertências e precauções)

  • Dulaglutidaagonista do receptor de GLP-1Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • DuloxetinaIRSNModerada

    Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and other anti-coagulants may add to this risk. (bula de Duloxetina, Advertências e precauções)

  • Patients taking tenofovir prodrugs who have impaired renal function and those taking nephrotoxic agents including non-steroidal anti-inflammatory drugs are at increased risk of developing renal-related adverse reactions. (bula de Elvitegravir + cobicistate + entricitabina + tenofovir, Advertências e precauções)

  • Empagliflozinainibidor do SGLT2Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Empagliflozina + metforminainibidor do SGLT2Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Enalaprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Enalapril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Enalaprilateinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Entricitabina + tenofovirantirretroviralModerada

    Individuals taking tenofovir prodrugs who have impaired renal function and those taking nephrotoxic agents including non-steroidal anti-inflammatory drugs are at increased risk of developing renal-related adverse reactions. (bula de Entricitabina + tenofovir, Advertências e precauções)

  • Eplerenonaantagonista da aldosteronaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Epoprostenolanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • Eptifibatidaantiagregante plaquetárioModerada

    Use of Thrombolytics, Anticoagulants, and Other Antiplatelet Agents Risk factors for bleeding include older age, a history of bleeding disorders, and concomitant use of drugs that increase the risk of bleeding (thrombolytics, oral anticoagulants, nonsteroidal anti-inflammatory drugs, and P2Y 12 inhibitors). (bula de Eptifibatida, Advertências e precauções)

  • ErlotinibeModerada

    Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (bula de Erlotinibe, Advertências e precauções)

  • EscitalopramISRSModerada

    Increased Risk of Bleeding: Concomitant use of nonsteroidal anti-inflammatory drugs, aspirin, other antiplatelet drugs, warfarin and other anticoagulants may increase risk ( 5.7 , 7) (bula de Escitalopram, Advertências e precauções)

  • Espironolactonaantagonista da aldosteronaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • CHCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid and temazepam. (bula de Etonogestrel + etinilestradiol, Interações medicamentosas)

  • Exenatidaagonista do receptor de GLP-1Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Febuxostateinibidor da xantina oxidaseModerada

    In order to prevent gout flares when ULORIC is initiated, concurrent prophylactic treatment with an NSAID or colchicine is recommended [see Dosage and Administration (2.4) ]. (bula de Febuxostate, Advertências e precauções)

  • Hyperventilation and Metabolic Acidosis: Sodium Phenylacetate and Sodium Benzoate Injection may cause side effects typically associated with salicylate overdose, such as hyperventilation and metabolic acidosis. (bula de Fenilacetato de sódio + benzoato de sódio, Advertências e precauções)

  • FenitoínaanticonvulsivanteModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Fenoximetilpenicilina (penicilina V)antibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • Fluconazolantifúngico azólicoModerada

    Non-steroidal anti-inflammatory drugs The C max and AUC of flurbiprofen were increased by 23% and 81%, respectively, when coadministered with fluconazole compared to administration of flurbiprofen alone. (bula de Fluconazol, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • FlunisolidacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • FluocinonidacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • FluoxetinaISRSModerada

    Use with NSAIDs, aspirin, warfarin, or other drugs that affect coagulation may potentiate the risk of gastrointestinal or other bleeding ( 5.7 ) (bula de Fluoxetina, Advertências e precauções)

  • FluticasonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Fluticasona + salmeterolcorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • FluvoxaminaISRSModerada

    Other Drugs Affecting Hemostasis: Increased risk of bleeding with concomitant use of NSAIDs, aspirin, or other drugs affecting coagulation ( 5.8 , 5.10 ). (bula de Fluvoxamina, Advertências e precauções)

  • FosfenitoínaanticonvulsivanteModerada

    …sulfamethoxazole-trimethoprim Other Acute alcohol intake, amiodarone, chloramphenicol, chlordiazepoxide, disulfiram, estrogen, fluvastatin, isoniazid, methylphenidate, phenothiazines, salicylates, ticlopidine, tolbutamide, trazodone, warfarin Drugs that may decrease phenytoin serum levels Antineoplastic agents usually in combination Bleomycin, carboplatin, cisplatin,… (bula de Fosfenitoína, Interações medicamentosas)

  • Fosinoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Fosinopril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Furosemidadiurético de alçaModerada

    Furosemide Clinical studies, as well as post marketing observations, have shown that Salsalate tablets, USP can reduce the natriuretic effect-of furosemide and thiazides in some patients. (bula de Salsalato, Interações medicamentosas)

  • Galantaminainibidor da colinesteraseModerada

    Therefore, patients should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those with an increased risk for developing ulcers, e.g., those with a history of ulcer disease or patients using concurrent nonsteroidal anti-inflammatory drugs (NSAIDS). (bula de Galantamina, Advertências e precauções)

  • GlibenclamidasulfonilureiaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Glibenclamida + metforminasulfonilureiaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • GlimepiridasulfonilureiaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • GlipizidasulfonilureiaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • GriseofulvinaantifúngicoModerada

    Serum salicylate concentrations may be decreased when griseofulvin is given concomitantly with salicylates. (bula de Griseofulvina, Interações medicamentosas)

  • HalobetasolcorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • HeparinaanticoagulanteModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (bula de Hialuronidase, Interações medicamentosas)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • HidrocortisonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • IbandronatobisfosfonatoModerada

    Use caution when co-prescribing aspirin/nonsteroidal anti-inflammatory drugs that may worsen gastrointestinal irritation. (bula de Ibandronato, Interações medicamentosas)

  • Indapamidadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Insulina asparteinsulinaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Insulina degludecainsulinaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Insulina detemirinsulinaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Insulina glarginainsulinaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Insulina lisproinsulinaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Irbesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and COX-2 inhibitors: Increased risk of renal impairment. (bula de Irbesartana, Interações medicamentosas)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Itraconazolantifúngico azólicoModerada

    Nonsteroidal Anti-Inflammatory Drugs Meloxicam Concomitant drug dose increase may be necessary. (bula de Itraconazol, Interações medicamentosas)

  • Latanoprostaanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • LevofloxacinofluoroquinolonaModerada

    Non-Steroidal Anti-Inflammatory Drugs The concomitant administration of a non-steroidal anti-inflammatory drug with a fluoroquinolone, including Levofloxacin in 5% Dextrose Injection, may increase the risk of CNS stimulation and convulsive seizures [see Warnings and Precautions (5.4) ]. (bula de Levofloxacino, Interações medicamentosas)

  • LevomilnacipranaIRSNModerada

    Increased Risk of Bleeding : Concomitant use of NSAIDs, aspirin, other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.5 ). (bula de Levomilnaciprana, Advertências e precauções)

  • Levonorgestrel + etinilestradiolanticoncepcional oralModerada

    Other Drugs Clinical effect Concomitant use of CHCs may decrease systemic exposure of acetaminophen, morphine, salicylic acid, and temazepam. (bula de Levonorgestrel + etinilestradiol, Interações medicamentosas)

  • Levotiroxinahormônio tireoidianoModerada

    An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (bula de Levotiroxina, Interações medicamentosas)

  • Linagliptinainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Linagliptina + metforminainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Liotironinahormônio tireoidianoModerada

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (bula de Liotironina, Interações medicamentosas)

  • Liraglutidaagonista do receptor de GLP-1Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Lisinoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Lítiomedicamento serotoninérgicoModerada

    Lithium NSAIDs have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance. (bula de Salsalato, Interações medicamentosas)

  • Losartanabloqueador do receptor da angiotensina II (BRA)Moderada

    NSAIDs: Increased risk of renal impairment and reduced diuretic, natriuretic, and antihypertensive effects. (bula de Losartana, Interações medicamentosas)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Memantina + donepezilainibidor da colinesteraseModerada

    Patients treated with NAMZARIC should be monitored closely for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Memantina + donepezila, Advertências e precauções)

  • ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (bula de Salsalato, Interações medicamentosas)

  • MesalazinasalicilatoModerada

    ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (bula de Salsalato, Interações medicamentosas)

  • MetforminabiguanidaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • MetilprednisolonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Metolazonadiurético tiazídicoModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Mifepristonainibidor da CYP3A4Moderada

    When given concomitantly with mifepristone, drugs that are substrates of CYP2C8/2C9 (including non-steroidal anti-inflammatory drugs, warfarin, and repaglinide) should be used at the smallest recommended doses, and patients should be closely monitored for adverse effects. [See Clinical Pharmacology ( 12.3 )] 7.5 Drugs Metabolized by CYP2B6 Mifepristone is an… (bula de Mifepristona, Interações medicamentosas)

  • MiglitolantidiabéticoModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • MilnacipranaIRSNModerada

    Caution patients about the risk of bleeding associated with the concomitant use of milnacipran hydrochloride and NSAIDs, aspirin, or other drugs that affect coagulation ( 5.9 ). (bula de Milnaciprana, Advertências e precauções)

  • Moexiprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • MometasonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • MoxifloxacinofluoroquinolonaModerada

    Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Although not observed with moxifloxacin in preclinical and clinical trials, the concomitant administration of a nonsteroidal anti-inflammatory drug with a quinolone may increase the risks of CNS stimulation and convulsions [see Warnings and Precautions ( 5.4 ), and Patient Counseling Information ( 17 )]. (bula de Moxifloxacino, Interações medicamentosas)

  • Nafcilinaantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • NateglinidameglitinidaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • NintedanibeModerada

    Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (bula de Nintedanibe, Advertências e precauções)

  • Nizatidinabloqueador H2Moderada

    In patients given very high doses (3,900 mg) of aspirin daily, increases in serum salicylate levels were seen when nizatidine, 150 mg b.i.d., was administered concurrently. (bula de Nizatidina, Interações medicamentosas)

  • CHCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, and temazepam. (bula de Norelgestromina + etinilestradiol, Interações medicamentosas)

  • Norgestimato + etinilestradiolanticoncepcional oralModerada

    COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (bula de Norgestimato + etinilestradiol, Interações medicamentosas)

  • Norgestrel + etinilestradiolanticoncepcional oralModerada

    COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (bula de Norgestrel + etinilestradiol, Interações medicamentosas)

  • OfloxacinofluoroquinolonaModerada

    Non Steroidal Anti-Inflammatory Drugs The concomitant administration of a non-steroidal anti-inflammatory drug with a quinolone, including ofloxacin, may increase the risk of CNS stimulation and convulsive seizures (see WARNINGS and PRECAUTIONS , General ). (bula de Ofloxacino, Interações medicamentosas)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    Use with NSAIDs, aspirin, warfarin, or other drugs that affect coagulation may potentiate the risk of gastrointestinal or other bleeding ( 5.16 ) (bula de Olanzapina + fluoxetina, Advertências e precauções)

  • Olmesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    NSAID use may lead to increased risk of renal impairment and loss of antihypertensive effect ( 7.2 ). (bula de Olmesartana, Interações medicamentosas)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Olopatadina + mometasonaanti-histamínicoModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Oxacilinaantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • ParoxetinaISRSModerada

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin, and other anticoagulant drugs may increase risk. (bula de Paroxetina, Advertências e precauções)

  • PentoxifilinametilxantinaModerada

    DRUG INTERACTIONS Bleeding has been reported in patients treated with pentoxifylline extended-release tablets with or without concomitant NSAIDs, anticoagulants, or platelet aggregation inhibitors. (bula de Pentoxifilina, Interações medicamentosas)

  • Perindoprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • PioglitazonatiazolidinedionaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Pioglitazona + glimepiridatiazolidinedionaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Pioglitazona + metforminatiazolidinedionaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • PrednisolonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • PrednisonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Quinaprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Quinapril + hidroclorotiazidainibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Ramiprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • RepaglinidameglitinidaModerada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Rivastigminainibidor da colinesteraseModerada

    Monitor patients using rivastigmine tartrate for symptoms of active or occult gastrointestinal bleeding, especially those at increased risk for developing ulcers, e.g., those with a history of ulcer disease or those receiving concurrent nonsteroidal anti-inflammatory drugs (NSAIDs). (bula de Rivastigmina, Advertências e precauções)

  • Sacubitril + valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): May lead to increased risk of renal impairment. (bula de Sacubitril + valsartana, Interações medicamentosas)

  • Saxagliptinainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Saxagliptina + metforminainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Semaglutidaagonista do receptor de GLP-1Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • SertralinaISRSModerada

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (bula de Sertralina, Advertências e precauções)

  • Sitagliptinainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Sitagliptina + metforminainibidor da DPP-4Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • Subsalicilato de bismutosalicilatoModerada

    ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (bula de Salsalato, Interações medicamentosas)

  • SulfadiazinasulfonamidaModerada

    Conversely, agents such as indomethacin, probenecid and salicylates may displace sulfonamides from plasma albumin and increase the concentrations of free drug in plasma. (bula de Sulfadiazina, Interações medicamentosas)

  • SulfassalazinasulfonamidaModerada

    ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (bula de Salsalato, Interações medicamentosas)

  • Tabaco e fumoTabaco e cannabisModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Telmisartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors): In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, co-administration of NSAIDs, including selective COX-2 inhibitors, with angiotensin II receptor antagonists, including telmisartan, may… (bula de Telmisartana, Interações medicamentosas)

  • Telmisartana + anlodipinobloqueador do receptor da angiotensina II (BRA)Moderada

    NSAIDS: Increased risk of renal impairment and loss of antihypertensive effect (7) (bula de Telmisartana + anlodipino, Interações medicamentosas)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Tirzepatidaagonista do receptor de GLP-1Moderada

    Salicylates may enhance the hypoglycemic effect of oral antidiabetic drugs of the sulfonylurea class. (bula de Salsalato, Interações medicamentosas)

  • TofacitinibeimunossupressorModerada

    Promptly evaluate patients treated with XELJANZ/XELJANZ XR who may be at increased risk for gastrointestinal perforation (e.g., patients with a history of diverticulitis or taking NSAIDs) and who present with new onset abdominal symptoms for early identification of gastrointestinal perforation [see Adverse Reactions (6.1) ] . (bula de Tofacitinibe, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Trandolaprilinibidor da ECAModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • TrazodonaantidepressivoModerada

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.5 ). (bula de Trazodona, Advertências e precauções)

  • Treprostinilaanálogo de prostaglandinaModerada

    Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. (bula de Salsalato, Advertências)

  • TriancinolonacorticosteroideModerada

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (bula de Salsalato, Advertências)

  • Trianterenodiurético poupador de potássioModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • UpadacitinibeimunossupressorModerada

    Monitor RINVOQ/RINVOQ LQ-treated patients who may be at risk for gastrointestinal perforation (e.g., patients with a history of diverticulitis and those taking concomitant medications including NSAIDs or corticosteroids). (bula de Upadacitinibe, Advertências e precauções)

  • Valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Non-Steroidal Anti-Inflammatory Drug (NSAID) use may lead to increased risk of renal impairment and loss of antihypertensive effect ( 7.2 ) (bula de Valsartana, Interações medicamentosas)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly. (bula de Salsalato, Advertências)

  • VarfarinaanticoagulanteModerada

    Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (bula de Salsalato, Interações medicamentosas)

  • VenlafaxinaIRSNModerada

    Concomitant use of aspirin, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), warfarin, and other anticoagulants may add to this risk. (bula de Venlafaxina, Advertências e precauções)

  • VilazodonaISRSModerada

    Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk ( 5.3 ) (bula de Vilazodona, Advertências e precauções)

  • Voriconazolantifúngico azólicoModerada

    NSAIDs Non-Steroidal Anti-Inflammatory Drug including. ibuprofen and diclofenac (CYP2C9 Inhibition) Increased Frequent monitoring for adverse reactions and toxicity related to NSAIDs. (bula de Voriconazol, Interações medicamentosas)

  • VortioxetinaantidepressivoModerada

    • Increased Risk of Bleeding : Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin, or other drugs that affect coagulation may increase risk ( 5.3 ). (bula de Vortioxetina, Advertências e precauções)

Menções leves (40)

  • AcebutololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Anlodipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Anlodipino + atorvastatinabloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • AtenololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • BetaxololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • BisoprololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • CarvedilolbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Clonidinaagonista alfa-adrenérgicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Diltiazembloqueador dos canais de cálcioLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • DoxazosinaalfabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • In vitro studies have shown no binding displacement between entacapone and other highly bound drugs, such as warfarin, salicylic acid, phenylbutazone, and diazepam. (bula de Entacapona, Precauções)

  • Felodipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • FenoxibenzaminaalfabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Finasteridainibidor da 5-alfa-redutaseLeve

    …angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives without evidence of clinically significant adverse interactions. (bula de Finasterida, Interações medicamentosas)

  • Guanfacinaagonista alfa-adrenérgicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • HidralazinavasodilatadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • InfliximabeimunossupressorLeve

    In RA, concomitant medications besides MTX were nonsteroidal anti-inflammatory agents (NSAIDs), folic acid, corticosteroids and/or narcotics. (bula de Infliximabe, Interações medicamentosas)

  • Isradipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • LabetalolbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (bula de Lenalidomida, Advertências e precauções)

  • Lofexidinaagonista alfa-adrenérgicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Mecamilaminaanti-hipertensivoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Metildopaanti-hipertensivoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • MetoprololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • MinoxidilvasodilatadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • NadololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • NebivololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Nicardipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Nifedipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Nisoldipinobloqueador dos canais de cálcio di-hidropiridínicoLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Nitroprusseto de sódiovasodilatadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • PindololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • PrazosinaalfabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • PropranololbetabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • RisedronatobisfosfonatoLeve

    Aspirin/Nonsteroidal Anti-Inflammatory Drugs In the Phase 3 study comparing Risedronate sodium delayed-release 35 mg once-a-week immediately following breakfast and risedronate sodium 5 mg daily, 18% of NSAID users (any use) in both groups developed upper gastrointestinal adverse reactions. (bula de Risedronato, Interações medicamentosas)

  • TerazosinaalfabloqueadorLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • Tizanidinarelaxante muscularLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

  • TocilizumabeimunossupressorLeve

    Concomitant Drugs for Treatment of Adult Indications In RA patients, population pharmacokinetic analyses did not detect any effect of methotrexate (MTX), non-steroidal anti-inflammatory drugs or corticosteroids on tocilizumab clearance. (bula de Tocilizumabe, Interações medicamentosas)

  • Verapamilbloqueador dos canais de cálcioLeve

    DRUG INTERACTIONS ACE-inhibitors Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors. (bula de Salsalato, Interações medicamentosas)

Verifique Salsalato com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.