Interações de Triantereno + hidroclorotiazida
Triantereno + hidroclorotiazida (Maxzide, Dyazide), diurético poupador de potássio, tem 421 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 47; moderadas: 342; leves: 30; casos em que uma bula relata não haver interação significativa: 2). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.
Interações segundo a bula
Interações graves (47)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Hyperkalemia Abnormal elevation of serum potassium levels (≥5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Advertência em caixa preta)
Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (bula de Alfacoriogonadotropina, Advertências)
CONTRAINDICATIONS Antikaliuretic Therapy and Potassium Supplementation Triamterene and hydrochlorothiazide should not be given to patients receiving other potassium-sparing agents such as spironolactone, amiloride, or other formulations containing triamterene. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (bula de Benazepril + hidroclorotiazida, Contraindicações)
Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (bula de Bicarbonato de sódio, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Hyperkalemia Abnormal elevation of serum potassium levels (≥5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Advertência em caixa preta)
Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (bula de Ciclosporina, Interações medicamentosas)
Such conditions include: chronic renal failure, uncontrolled diabetes mellitus, acute dehydration, strenuous physical exercise in unconditioned individuals, adrenal insufficiency, extensive tissue breakdown or the administration of a potassium-sparing agent (such as triamterene, spironolactone or amiloride). (bula de Citrato de potássio, Contraindicações)
Potassium chloride is contraindicated in patients on triamterene and amiloride. (bula de Cloreto de potássio, Contraindicações)
Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (bula de Clozapina, Advertência em caixa preta)
- DiazóxidoGrave
CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (bula de Diazóxido, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (bula de Dofetilida, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (bula de Droperidol, Advertência em caixa preta)
Avoid potassium sparing agents in patients with heart failure ( 7.3 ). (bula de Enalapril, Interações medicamentosas)
…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Enalaprilate, Advertências)
CONTRAINDICATIONS Antikaliuretic Therapy and Potassium Supplementation Triamterene and hydrochlorothiazide should not be given to patients receiving other potassium-sparing agents such as spironolactone, amiloride, or other formulations containing triamterene. (bula de Triantereno + hidroclorotiazida, Contraindicações)
…of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (bula de Eptifibatida, Contraindicações)
CONTRAINDICATIONS Antikaliuretic Therapy and Potassium Supplementation Triamterene and hydrochlorothiazide should not be given to patients receiving other potassium-sparing agents such as spironolactone, amiloride, or other formulations containing triamterene. (bula de Triantereno + hidroclorotiazida, Contraindicações)
CONTRAINDICATIONS Antikaliuretic Therapy and Potassium Supplementation Triamterene and hydrochlorothiazide should not be given to patients receiving other potassium-sparing agents such as spironolactone, amiloride, or other formulations containing triamterene. (bula de Triantereno + hidroclorotiazida, Contraindicações)
- FolitropinaGrave
Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (bula de Folitropina, Advertências e precauções)
Hyperkalemia Abnormal elevation of serum potassium levels (≥5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Advertência em caixa preta)
The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Gentamicina, Advertência em caixa preta)
• GI Toxicity with Solid Oral Dosage Forms of Potassium Chloride : Concomitant use is not recommended. (bula de Glicopirrônio, Interações medicamentosas)
Indomethacin and triamterene should not be administered together. (bula de Indometacina, Advertências e precauções)
- IrinotecanoGrave
Avoid diuretics or laxatives in patients with diarrhea. (bula de Irinotecano, Advertências e precauções)
Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (bula de Itraconazol, Interações medicamentosas)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (bula de Metolazona, Advertências)
Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (bula de Minoxidil, Advertência em caixa preta)
The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Neomicina, Advertência em caixa preta)
Concomitant potassium-containing salt substitutes should also not be used. (bula de Triantereno + hidroclorotiazida, Contraindicações)
…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Quinapril, Advertências)
…sometimes associated with oliguria and/or progressive azotemia, and rarely acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis or severe volume and/or salt depletion of any etiology. (bula de Quinapril + hidroclorotiazida, Advertências)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
…coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (bula de Tadalafila, Advertências e precauções)
Hyperkalemia Abnormal elevation of serum potassium levels (≥5.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Advertência em caixa preta)
CONTRAINDICATIONS Antikaliuretic Therapy and Potassium Supplementation Triamterene and hydrochlorothiazide should not be given to patients receiving other potassium-sparing agents such as spironolactone, amiloride, or other formulations containing triamterene. (bula de Triantereno + hidroclorotiazida, Contraindicações)
The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (bula de Trióxido de arsênio, Advertências e precauções)
Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)
Interações moderadas (342)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (bula de Ácido zoledrônico, Advertências e precauções)
- AlfaepoetinaModerada
Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (bula de Alfaepoetina, Advertências e precauções)
Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (bula de Alfuzosina, Advertências e precauções)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (bula de Alopurinol, Advertências e precauções)
Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (bula de Amicacina, Interações medicamentosas)
Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (bula de Amiodarona, Advertências e precauções)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (bula de Anfepramona (dietilpropiona), Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Arformoterol, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (bula de Aripiprazol, Interações medicamentosas)
There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (bula de Armodafinila, Advertências e precauções)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (bula de Asenapina, Advertências e precauções)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (bula de Atomoxetina, Interações medicamentosas)
• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (bula de Avanafila, Advertências e precauções)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Beladona + ópio, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Amphetamines may decrease the hypotensive effect of antihypertensives. (bula de Benzfetamina, Interações medicamentosas)
…with renal insufficiency: blood from blood bank (may contain potassium up to 30 mEq/L of plasma or up to 65 mEq/L of whole blood when stored for more than 10 days); low-salt milk (may contain potassium up to 60 mEq/L); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Chronic or overuse of laxatives may reduce serum potassium levels by promoting excessive potassium loss from the intestinal tract; laxatives may interfere with the potassium-retaining effects of triamterene. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- BortezomibeModerada
Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (bula de Bortezomibe, Advertências e precauções)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Brexpiprazol, Advertências e precauções)
Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (bula de Brimonidina, Interações medicamentosas)
Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (bula de Brimonidina + timolol, Interações medicamentosas)
Use caution in patients taking antihypertensive medications. (bula de Bromocriptina, Advertências e precauções)
Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (bula de Bronfeniramina + pseudoefedrina + dextrometorfano, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Buprenorfina, Interações medicamentosas)
Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Buprenorfina + naloxona, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Butalbital + paracetamol + cafeína + codeína, Interações medicamentosas)
Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (bula de Calcitriol, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (bula de Carbamazepina, Advertências e precauções)
- CarbidopaModerada
Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (bula de Carbidopa, Interações medicamentosas)
Antihypertensive drugs: May cause symptomatic postural hypotension. (bula de Carbidopa + levodopa, Interações medicamentosas)
Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (bula de Carbidopa + levodopa + entacapona, Interações medicamentosas)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Cariprazina, Advertências e precauções)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (bula de Cefepima, Interações medicamentosas)
Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (bula de Ceftazidima, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (bula de Cetoconazol, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
…inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (bula de Ciclofosfamida, Interações medicamentosas)
Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (bula de Ciclossilicato de zircônio sódico, Advertências e precauções)
Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Citalopram, Advertências e precauções)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Consider use of diuretics and/or albumin. (bula de Clofarabina, Advertências e precauções)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- Cloreto de cálcioModerada
Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (bula de Cloreto de cálcio, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Clorpromazina, Precauções)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Codeína, Interações medicamentosas)
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (bula de Colestipol, Interações medicamentosas)
Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (bula de Colestiramina, Interações medicamentosas)
- CorticotropinaModerada
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (bula de Desipramina, Advertências)
- DesmopressinaModerada
…Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (bula de Desmopressina, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (bula de Desvenlafaxina, Advertências e precauções)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Dexlansoprazol, Advertências e precauções)
• Antihypertensive Drugs: Monitor blood pressure. (bula de Dexmetilfenidato, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (bula de Digoxina, Advertências e precauções)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Chronic or overuse of laxatives may reduce serum potassium levels by promoting excessive potassium loss from the intestinal tract; laxatives may interfere with the potassium-retaining effects of triamterene. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Doxercalciferol, Advertências e precauções)
Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (bula de Drospirenona + etinilestradiol, Advertências e precauções)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (bula de Duloxetina, Advertências e precauções)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
…Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (bula de Epinefrina (adrenalina), Interações medicamentosas)
Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (bula de Epoprostenol, Interações medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)
Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (bula de Esmolol, Interações medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Esomeprazol, Advertências e precauções)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
…hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (bula de Fenelzina, Advertências)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
…treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (bula de Fentanila, Advertências e precauções)
Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively. (bula de Fentermina + topiramato, Interações medicamentosas)
Hydrochlorothiazide In a pharmacokinetic interaction study, coadministration of multiple-dose hydrochlorothiazide to healthy volunteers receiving fluconazole increased plasma concentrations of fluconazole by 40%. (bula de Fluconazol, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Fluoxetina, Advertências e precauções)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Fluvoxamina, Advertências e precauções)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
• Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Formoterol, Interações medicamentosas)
When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (bula de Foscarnete, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (bula de Haloperidol, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Hidrocodona, Interações medicamentosas)
Diuretics : Hydrocodone may reduce the efficacy of diuretics. (bula de Hidrocodona + clorfeniramina, Interações medicamentosas)
Diuretics : Hydrocodone may reduce the efficacy of diuretics. (bula de Hidrocodona + homatropina, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Hidrocodona + paracetamol, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Hidromorfona, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Iloperidona, Advertências e precauções)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (bula de Imipramina, Advertências)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- Iodeto de potássioModerada
Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (bula de Iodeto de potássio, Interações medicamentosas)
Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (bula de Ipratrópio + salbutamol, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Chronic or overuse of laxatives may reduce serum potassium levels by promoting excessive potassium loss from the intestinal tract; laxatives may interfere with the potassium-retaining effects of triamterene. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Lansoprazol, Advertências e precauções)
Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (bula de Levomilnaciprana, Advertências e precauções)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Levorfanol, Interações medicamentosas)
Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (bula de Levossalbutamol, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (bula de Linezolida, Advertências e precauções)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Lithium Lithium generally should not be given with diuretics because they reduce its renal clearance and increase the risk of lithium toxicity. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (bula de Lumateperona, Advertências e precauções)
Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (bula de Lurasidona, Advertências e precauções)
Chronic or overuse of laxatives may reduce serum potassium levels by promoting excessive potassium loss from the intestinal tract; laxatives may interfere with the potassium-retaining effects of triamterene. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (bula de Metadona, Advertências e precauções)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The effectiveness of methenamine may be decreased when used concurrently with hydrochlorothiazide because of alkalinization of the urine. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Antihypertensive Drugs: Monitor blood pressure. (bula de Metilfenidato, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (bula de Milnaciprana, Advertências e precauções)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (bula de Mirtazapina, Advertências e precauções)
However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (bula de Modafinila, Advertências e precauções)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Morfina, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Nalbufina, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- Niacina (ácido nicotínico)Moderada
Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (bula de Niacina (ácido nicotínico), Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (bula de Nimodipino, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Antihypertensives: Possible additive hypotensive effects. (bula de Nitroglicerina, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
…of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (bula de Olanzapina, Advertências e precauções)
…and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Olanzapina + fluoxetina, Advertências e precauções)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oliceridina, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol, Advertências e precauções)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol + bicarbonato de sódio, Advertências e precauções)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oxicodona, Interações medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oxicodona + paracetamol, Interações medicamentosas)
Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Oximorfona, Interações medicamentosas)
Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Paliperidona, Advertências e precauções)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Pantoprazol, Advertências e precauções)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Paracetamol + codeína, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Paricalcitol, Advertências e precauções)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (bula de Paroxetina, Advertências e precauções)
- PazopanibeModerada
Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)
Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Pentazocina + naloxona, Interações medicamentosas)
Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (bula de Pentoxifilina, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Petidina (meperidina), Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Triantereno + hidroclorotiazida, Advertências)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Exchange resins, such as sodium polystyrene sulfonate, whether administered orally or rectally, reduce serum potassium levels by sodium replacement of the potassium; fluid retention may occur in some patients because of the increased sodium intake. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Proclorperazina, Precauções)
Diuretics : Codeine may reduce the efficacy of diuretics. (bula de Prometazina + codeína, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Quetiapina, Advertências e precauções)
Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (bula de Quinidina, Interações medicamentosas)
For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Rabeprazol, Advertências e precauções)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (bula de Riociguate, Advertências e precauções)
Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (bula de Risperidona, Advertências e precauções)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics: Use with caution. (bula de Salbutamol, Interações medicamentosas)
• Diuretics: Use with caution. (bula de Salmeterol, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Chronic or overuse of laxatives may reduce serum potassium levels by promoting excessive potassium loss from the intestinal tract; laxatives may interfere with the potassium-retaining effects of triamterene. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Sertralina, Advertências e precauções)
Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (bula de Sildenafila, Advertências e precauções)
However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (bula de Silodosina, Advertências e precauções)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- SorafenibeModerada
Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (bula de Sorafenibe, Advertências e precauções)
Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (bula de Sotalol, Advertências e precauções)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- SunitinibeModerada
Initiate and/or adjust antihypertensive therapy as appropriate. (bula de Sunitinibe, Advertências e precauções)
Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (bula de Suxametônio (succinilcolina), Advertências e precauções)
• Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (bula de Tacrolimo, Advertências e precauções)
…use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Tapentadol, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (bula de Terbutalina, Precauções)
In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (bula de Testosterona, Advertências e precauções)
Oral Hypoglycemic Drugs Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (bula de Tobramicina, Interações medicamentosas)
Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
- TolvaptanaModerada
Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (bula de Tolvaptana, Advertências e precauções)
Hydrochlorothiazide (HCTZ) Topiramate C max and AUC increased when HCTZ was added to immediate-release topiramate. (bula de Topiramato, Interações medicamentosas)
Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (bula de Toremifeno, Interações medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Tramadol, Interações medicamentosas)
Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (bula de Tramadol + paracetamol, Interações medicamentosas)
Drug Interactions Angiotensin-Converting Enzyme Inhibitors Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (bula de Trazodona, Advertências e precauções)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Trifluoperazina, Precauções)
• Diuretics: Use with caution. (bula de Umeclidínio + vilanterol, Interações medicamentosas)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Other Considerations Concurrent use of hydrochlorothiazide with amphotericin B or corticosteroids or corticotropin (ACTH) may intensify electrolyte imbalance, particularly hypokalemia, although the presence of triamterene minimizes the hypokalemic effect. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (bula de Vardenafila, Interações medicamentosas)
The effect of oral anticoagulants may be decreased when used concurrently with hydrochlorothiazide; dosage adjustments may be necessary. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Venlafaxina, Advertências e precauções)
Thiazides may add to or potentiate the action of other antihypertensive drugs. (bula de Triantereno + hidroclorotiazida, Interações medicamentosas)
Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (bula de Vilazodona, Advertências e precauções)
Os diuréticos tiazídicos reduzem a excreção de cálcio; combinado com suplementos de vitamina D e de cálcio, isso pode levar a hipercalcemia, especialmente em idosos. (NIH Office of Dietary Supplements, Vitamin D)
Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (bula de Vortioxetina, Advertências e precauções)
Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (bula de Ziprasidona, Advertências e precauções)
Menções leves (30)
Coadministration of 1 Dyazide (triamterene/hydrochlorothiazide) resulted in a higher plasma amantadine hydrochloride concentration in a 61-year old man receiving amantadine hydrochloride 100 mg TID for Parkinson's disease. (bula de Amantadina, Interações medicamentosas)
- AmbrisentanaLeve
Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (bula de Ambrisentana, Advertências e precauções)
Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (bula de Bosentana, Advertências e precauções)
In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs. (bula de Butorfanol, Advertências)
Os diuréticos tiazídicos reduzem a excreção de cálcio, de modo que um consumo alto de cálcio pode elevar o cálcio no sangue. (NIH Office of Dietary Supplements, Calcium)
- DasatinibeLeve
Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (bula de Dasatinibe, Advertências e precauções)
If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (bula de Desogestrel + etinilestradiol, Advertências)
Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (bula de Dextroanfetamina, Interações medicamentosas)
Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (bula de Dobutamina, Interações medicamentosas)
- DocetaxelLeve
Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (bula de Docetaxel, Advertências e precauções)
Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (bula de Dronedarona, Advertências e precauções)
Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (bula de Efedrina, Interações medicamentosas)
In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Estrogênios esterificados + metiltestosterona, Advertências)
In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, ULORIC does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology (12.3) ]. (bula de Febuxostate, Interações medicamentosas)
…clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (bula de Finasterida, Interações medicamentosas)
Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (bula de Flecainida, Interações medicamentosas)
Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (bula de Gliconato de cálcio, Interações medicamentosas)
Drug interactions may occur when anticholinergics are used with the following medications: antacids, antidiarrheals (adsorbent), other anticholinergics, antimyasthenics, cyclopropane, haloperidol, ketoconazole, metoclopramide, opioid (narcotic) analgesics, and potassium chloride. (bula de Hiosciamina, Interações medicamentosas)
- IcatibantoLeve
ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (bula de Icatibanto, Interações medicamentosas)
Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (bula de Imatinibe, Advertências e precauções)
- MacitentanaLeve
Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (bula de Macitentana, Advertências e precauções)
O uso prolongado de diuréticos de alça e tiazídicos aumenta a perda de magnésio na urina. (NIH Office of Dietary Supplements, Magnesium)
In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Metiltestosterona, Advertências)
In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (bula de Mexiletina, Interações medicamentosas)
…for Drug Interaction: It appears possible, although there is no supporting experimental evidence, that the high renal clearance of desglymidodrine (a base) is due to active tubular secretion by the base-secreting system also responsible for the secretion of such drugs as metformin, cimetidine, ranitidine, procainamide, triamterene, flecainide, and quinidine. (bula de Midodrina, Precauções)
…been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (bula de Milrinona, Interações medicamentosas)
The antihypertensive action of guanethidine and similar agents may be blocked. (bula de Nortriptilina, Advertências)
Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (bula de Protriptilina, Advertências)
There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (bula de Terbinafina, Interações medicamentosas)
Os diuréticos tiazídicos aumentam a perda de zinco na urina com o uso prolongado. (NIH Office of Dietary Supplements, Zinc)
Nenhuma interação significativa relatada (2)
Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (bula de Pamidronato, Interações medicamentosas)
Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (bula de Ropinirol, Interações medicamentosas)
Verifique Triantereno + hidroclorotiazida com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.
Abrir no verificadorNão é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.