Interação entre Amoxicilina + clavulanato de potássio e Piperacilina + tazobactam
Amoxicilina + clavulanato de potássio e Piperacilina + tazobactam: ambas as bulas profissionais sinalizam esta combinação com a linguagem mais forte, como uma contraindicação, uma advertência em caixa preta ou uma instrução para evitá-la.
Não combine sem a orientação de um prescritor. A linguagem da bula abaixo é a mais forte que a FDA usa.
O que dizem as bulas da FDA
Da bula de Amoxicilina + clavulanato de potássio (Amoxicillin and Clavulanate Potassium) · em vigor desde 2026-07-07
History of a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to AUGMENTIN or to other beta‑lactams (e.g., penicillins or cephalosporins).
Serious Hypersensitivity Reactions Amoxicillin and Clavulanate Potassium Extended Release Tablets is contraindicated in patients with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to amoxicillin, clavulanate or to other beta-lactam antibacterial drugs (e.g., penicillins and cephalosporins).
Da bula de Piperacilina + tazobactam (Piperacillin and Tazobactam and Sodium Chloride) · em vigor desde 2026-05-08
Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients.
Nephrotoxicity in Critically Ill Patients The use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients [see Adverse Reactions (6.1) ].
As with other penicillins, the administration of piperacillin and tazobactam may result in a false-positive reaction for glucose in the urine using a copper-reduction method (CLINITEST ® ).
As with other penicillins, piperacillin and tazobactam may cause neuromuscular excitability or seizures.
Central Nervous System Adverse Reactions As with other penicillins, piperacillin and tazobactam may cause neuromuscular excitability or seizures.
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Abrir no verificadorNão é aconselhamento médico. Interaction Checker cita o texto das bulas da FDA e fichas informativas do NIH. A importância de uma interação para você depende das doses, dos horários, da função renal e hepática e de outras condições de saúde. Confirme com um farmacêutico ou com o prescritor.