Interações de Bisoprolol + hidroclorotiazida

Bisoprolol + hidroclorotiazida (Ziac), betabloqueador, tem 476 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 43; moderadas: 373; leves: 57; casos em que uma bula relata não haver interação significativa: 3). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Aparência de Bisoprolol + hidroclorotiazida

Todas as 24 versões
Bisoprolol + hidroclorotiazida 6.25 mg / 5 mg em comprimido: rosa, redondo, 8 mm, com a gravação UL de um lado e ll do outro.
UL / ll
6.25 mg / 5 mg · rosa · redondo · 8 mm
Unichem Pharmaceuticals (U…
Bisoprolol + hidroclorotiazida 2.5 mg / 6.25 mg em comprimido: amarelo, redondo, 7 mm, com a gravação 113.
113
2.5 mg / 6.25 mg · amarelo · redondo · 7 mm
Viona
Bisoprolol + hidroclorotiazida 5 mg / 6.25 mg em comprimido: rosa, redondo, 7 mm, com a gravação 114.
114
5 mg / 6.25 mg · rosa · redondo · 7 mm
Viona
Bisoprolol + hidroclorotiazida 10 mg / 6.25 mg em comprimido: branco, redondo, 7 mm, com a gravação 115.
115
10 mg / 6.25 mg · branco · redondo · 7 mm
Viona

Representações criadas a partir das listas de produtos das bulas da FDA: cor, formato, tamanho e gravação. 24 versões documentadas de 10 fabricantes.

Interações segundo a bula

Interações graves (43)

  • Acetazolamidainibidor da anidrase carbônicaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Ácido etacrínicodiurético de alçaGrave

    CONTRAINDICATIONS All diuretics, including ethacrynic acid, are contraindicated in anuria. (bula de Ácido etacrínico, Contraindicações)

  • Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (bula de Alfacoriogonadotropina, Advertências)

  • Amiloridadiurético poupador de potássioGrave

    Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (bula de Amilorida, Advertência em caixa preta)

  • Benazepril + hidroclorotiazidainibidor da ECAGrave

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (bula de Benazepril + hidroclorotiazida, Contraindicações)

  • Bicarbonato de sódioantiácidoGrave

    Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (bula de Bicarbonato de sódio, Contraindicações)

  • Brinzolamidainibidor da anidrase carbônicaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Bumetanidadiurético de alçaGrave

    WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (bula de Bumetanida, Advertência em caixa preta)

  • CiclosporinaimunossupressorGrave

    Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (bula de Ciclosporina, Interações medicamentosas)

  • Citrato de potássiosuplemento de potássioGrave

    The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (bula de Citrato de potássio, Interações medicamentosas)

  • ClozapinaantipsicóticoGrave

    Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (bula de Clozapina, Advertência em caixa preta)

  • CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (bula de Diazóxido, Contraindicações)

  • Diclorfenamidainibidor da anidrase carbônicaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • DofetilidaantiarrítmicoGrave

    The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (bula de Dofetilida, Contraindicações)

  • Dorzolamidainibidor da anidrase carbônicaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Dorzolamida + timololinibidor da anidrase carbônicaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Droperidolantagonista da dopaminaGrave

    Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (bula de Droperidol, Advertência em caixa preta)

  • Enalaprilateinibidor da ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Enalaprilate, Advertências)

  • Eplerenonaantagonista da aldosteronaGrave

    …• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (bula de Eplerenona, Contraindicações)

  • Eptifibatidaantiagregante plaquetárioGrave

    …of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (bula de Eptifibatida, Contraindicações)

  • FlecainidaantiarrítmicoGrave

    Concomitant negative chronotropic therapy such as digoxin or beta-blockers may lower the risk of this complication. (bula de Flecainida, Advertência em caixa preta)

  • Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (bula de Folitropina, Advertências e precauções)

  • GentamicinaaminoglicosídeoGrave

    The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Gentamicina, Advertência em caixa preta)

  • Avoid diuretics or laxatives in patients with diarrhea. (bula de Irinotecano, Advertências e precauções)

  • Itraconazolantifúngico azólicoGrave

    Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (bula de Itraconazol, Interações medicamentosas)

  • Metazolamidainibidor da anidrase carbônicaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • In addition, life-threatening arrhythmias may occur during anesthesia and surgery, and may require treatment with a beta-blocker or lidocaine. (bula de Metirosina, Advertências)

  • Metolazonadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (bula de Metolazona, Advertências)

  • MinoxidilvasodilatadorGrave

    Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (bula de Minoxidil, Advertência em caixa preta)

  • NebivololbetabloqueadorGrave

    Hypotensive Agents Do not use BYSTOLIC with other β-blockers. (bula de Nebivolol, Interações medicamentosas)

  • NeomicinaaminoglicosídeoGrave

    The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (bula de Neomicina, Advertência em caixa preta)

  • Risk factors include high dose or overdose, rapid administration (see WARNINGS and DOSAGE AND ADMINISTRATION ), repeated doses, previous administration of protamine, and current or previous use of protamine-containing drugs (NPH insulin, protamine zinc insulin, and certain beta-blockers). (bula de Protamina, Advertência em caixa preta)

  • Quinaprilinibidor da ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (bula de Quinapril, Advertências)

  • RepaglinidameglitinidaGrave

    Examples: beta-blockers, clonidine, guanethidine, and reserpine Clopidogrel : Avoid concomitant use; if used concomitantly initiate at 0.5 mg before each meal and limit total daily dose to 4 mg ( 7 ) (bula de Repaglinida, Interações medicamentosas)

  • Rivastigminainibidor da colinesteraseGrave

    Concomitant use with metoclopramide, beta-blockers, or cholinomimetic and anticholinergic drugs is not recommended ( 7.1 , 7.2 , 7.3 ) (bula de Rivastigmina, Interações medicamentosas)

  • SulfadiazinasulfonamidaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Sulfadiazina de pratasulfonamidaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • SulfassalazinasulfonamidaGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Tadalafilainibidor da PDE5Grave

    …coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (bula de Tadalafila, Advertências e precauções)

  • Tranilciprominainibidor da MAOGrave

    …Syndrome (SS) c ] Agents with blood pressure-reducing effects Use with caution d Hypotension e Non-selective H1 receptor antagonists Contraindicated a Increased anticholinergic effects Beta-adrenergic blockers (see also agents or procedures with blood pressure-reducing effects) Use with the caution d More pronounced bradycardia, postural hypotension e Blood glucose-lowering… (bula de Tranilcipromina, Interações medicamentosas)

  • Trióxido de arsêniomedicamento que prolonga o intervalo QTGrave

    The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (bula de Trióxido de arsênio, Advertências e precauções)

  • ZonisamidaanticonvulsivanteGrave

    CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

Interações moderadas (373)

  • AcarboseantidiabéticoModerada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • AcebutololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Ácido acetilsalicílico + dipiridamolantiagregante plaquetárioModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Ácido mefenâmicoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Ácido zoledrônicobisfosfonatoModerada

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (bula de Ácido zoledrônico, Advertências e precauções)

  • AdenosinaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • ÁlcoolÁlcoolModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • AlfaepoetinaModerada

    Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (bula de Alfaepoetina, Advertências e precauções)

  • AlfuzosinaalfabloqueadorModerada

    Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (bula de Alfuzosina, Advertências e precauções)

  • Alisquirenoanti-hipertensivoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Alogliptinainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alogliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alopurinolinibidor da xantina oxidaseModerada

    Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (bula de Alopurinol, Advertências e precauções)

  • AmicacinaaminoglicosídeoModerada

    Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (bula de Amicacina, Interações medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Amoxicilinaantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Amoxicilina + clavulanato de potássioantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Ampicilinaantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Ampicilina + sulbactamantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Anfepramona (dietilpropiona)estimulante do SNCModerada

    The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (bula de Anfepramona (dietilpropiona), Interações medicamentosas)

  • Anlodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Anlodipino + atorvastatinabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Anlodipino + benazeprilbloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Anlodipino + olmesartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Anlodipino + valsartanabloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Arformoterolagonista beta-adrenérgicoModerada

    Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Arformoterol, Interações medicamentosas)

  • AripiprazolantipsicóticoModerada

    Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (bula de Aripiprazol, Interações medicamentosas)

  • Armodafinilaestimulante do SNCModerada

    There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (bula de Armodafinila, Advertências e precauções)

  • Articaína + epinefrinaanestésico localModerada

    Such patients may be unresponsive to the usual doses of epinephrine used to treat allergic reactions. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • AsenapinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (bula de Asenapina, Advertências e precauções)

  • AtenololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Atenolol + clortalidonabetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Atomoxetinainibidor da recaptação de noradrenalinaModerada

    Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (bula de Atomoxetina, Interações medicamentosas)

  • Avanafilainibidor da PDE5Moderada

    • Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (bula de Avanafila, Advertências e precauções)

  • Azilsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Baclofenorelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Beladona + ópioopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Benazeprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Benzfetaminaestimulante do SNCModerada

    Amphetamines may decrease the hypotensive effect of antihypertensives. (bula de Benzfetamina, Interações medicamentosas)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • BetaxololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Bexagliflozinainibidor do SGLT2Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • BisoprololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • BortezomibeModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (bula de Bortezomibe, Advertências e precauções)

  • BrexpiprazolantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Brexpiprazol, Advertências e precauções)

  • Brimonidinaagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (bula de Brimonidina, Interações medicamentosas)

  • Brimonidina + timololagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (bula de Brimonidina + timolol, Interações medicamentosas)

  • Bromocriptinaagonista da dopaminaModerada

    Use caution in patients taking antihypertensive medications. (bula de Bromocriptina, Advertências e precauções)

  • Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (bula de Bronfeniramina + pseudoefedrina + dextrometorfano, Interações medicamentosas)

  • Budesonida + formoterolcorticosteroideModerada

    Beta-blockers: Use with caution. (bula de Budesonida + formoterol, Interações medicamentosas)

  • Bupivacaínaanestésico localModerada

    Risk of Hypertension and Bradycardia Due to Drug Interactions Between MARCAINE WITH EPINEPHRINE and Nonselective Beta-Adrenergic Antagonists Administration of MARCAINE WITH EPINEPHRINE (containing a vasoconstrictor) in patients receiving nonselective beta-adrenergic antagonists may cause severe hypertension and bradycardia. (bula de Bupivacaína, Advertências e precauções)

  • Bupivacaína + epinefrinaanestésico localModerada

    Such patients may be unresponsive to the usual doses of epinephrine used to treat allergic reactions. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • BuprenorfinaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • BupropionaantidepressivoModerada

    Drugs Metabolized by CYP2D6: Bupropion inhibits CYP2D6 and can increase concentrations of: antidepressants (e.g., venlafaxine, nortriptyline, imipramine, desipramine, paroxetine, fluoxetine, sertraline), antipsychotics (e.g., haloperidol, risperidone, thioridazine), beta-blockers (e.g., metoprolol), and Type 1C antiarrhythmics (e.g., propafenone, flecainide). (bula de Bupropiona, Interações medicamentosas)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Butalbital + paracetamolbarbitúricoModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • ButorfanolopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Calcitriolanálogo da vitamina DModerada

    Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (bula de Calcitriol, Interações medicamentosas)

  • Canagliflozinainibidor do SGLT2Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Candesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Captoprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • CarbamazepinaanticonvulsivanteModerada

    Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (bula de Carbamazepina, Advertências e precauções)

  • CarbidopaModerada

    Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (bula de Carbidopa, Interações medicamentosas)

  • Carbidopa + levodopamedicamento dopaminérgicoModerada

    Antihypertensive drugs: May cause symptomatic postural hypotension. (bula de Carbidopa + levodopa, Interações medicamentosas)

  • Carbidopa + levodopa + entacaponamedicamento dopaminérgicoModerada

    Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (bula de Carbidopa + levodopa + entacapona, Interações medicamentosas)

  • CariprazinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Cariprazina, Advertências e precauções)

  • Carisoprodolrelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • CarvedilolbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • CefepimacefalosporinaModerada

    Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (bula de Cefepima, Interações medicamentosas)

  • CeftazidimacefalosporinaModerada

    Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (bula de Ceftazidima, Interações medicamentosas)

  • CelecoxibeAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Cetoconazolantifúngico azólicoModerada

    Antivirals indinavir, maraviroc, saquinavir Beta Blockers nadolol Calcium Channel Blockers felodipine, nisoldipine other dihydropyridines, verapamil Calcium channel blockers can have a negative inotropic effect which may be additive to those of ketoconazole. (bula de Cetoconazol, Interações medicamentosas)

  • CetoprofenoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • CetorolacoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Cevimelinaagonista colinérgicoModerada

    DRUG INTERACTIONS Cevimeline should be administered with caution to patients taking beta adrenergic antagonists, because of the possibility of conduction disturbances. (bula de Cevimelina, Interações medicamentosas)

  • Ciclobenzaprinarelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • CiclofosfamidaimunossupressorModerada

    …inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (bula de Ciclofosfamida, Interações medicamentosas)

  • Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (bula de Ciclossilicato de zircônio sódico, Advertências e precauções)

  • CitalopramISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Citalopram, Advertências e precauções)

  • ClofarabinaantimetabólitoModerada

    Consider use of diuretics and/or albumin. (bula de Clofarabina, Advertências e precauções)

  • Clonidinaagonista alfa-adrenérgicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (bula de Cloreto de cálcio, Interações medicamentosas)

  • Clorotiazidadiurético tiazídicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • ClorpromazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Clorpromazina, Precauções)

  • Clortalidonadiurético tiazídicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Clorzoxazonarelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • CodeínaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Colestipolsequestrante de ácidos biliaresModerada

    Single doses of cholestyramine and colestipol resins bind the hydrochlorothiazide and reduce its absorption in the gastrointestinal tract by up to 85 percent and 43 percent, respectively. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Colestiraminasequestrante de ácidos biliaresModerada

    Single doses of cholestyramine and colestipol resins bind the hydrochlorothiazide and reduce its absorption in the gastrointestinal tract by up to 85 percent and 43 percent, respectively. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Dantrolenorelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Dapagliflozinainibidor do SGLT2Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Dapagliflozina + metforminainibidor do SGLT2Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • DarunavirantirretroviralModerada

    …initial dosing and titration of quetiapine. e.g. perphenazine, risperidone, thioridazine ↑ antipsychotics A decrease in the dose of antipsychotics that are metabolized by CYP3A or CYP2D6 may be needed when co-administered with PREZISTA/ritonavir. β-Blockers : e.g. carvedilol, metoprolol, timolol ↑ beta-blockers Clinical monitoring of patients is recommended. (bula de Darunavir, Interações medicamentosas)

  • Darunavir + cobicistateantirretroviralModerada

    Initiation of quetiapine in patients taking PREZCOBIX or PREZCOBIX PED : Refer to the quetiapine prescribing information for initial dosing and titration of quetiapine. β-Blockers: e.g. carvedilol, metoprolol, timolol ↑ beta-blockers Clinical monitoring is recommended for co-administration with beta-blockers that are metabolized by CYP2D6. (bula de Darunavir + cobicistate, Interações medicamentosas)

  • Desipraminaantidepressivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (bula de Desipramina, Advertências)

  • …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (bula de Desmopressina, Interações medicamentosas)

  • DesvenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (bula de Desvenlafaxina, Advertências e precauções)

  • Deutetrabenazinainibidor do VMAT2Moderada

    Patients receiving catecholamine-depleting drugs, such as reserpine or guanethidine, should be closely monitored because the added beta-adrenergic blocking action of bisoprolol fumarate may produce excessive reduction of sympathetic activity. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Dexlansoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Dexlansoprazol, Advertências e precauções)

  • Dexmetilfenidatoestimulante do SNCModerada

    • Antihypertensive Drugs: Monitor blood pressure. (bula de Dexmetilfenidato, Interações medicamentosas)

  • Di-hidroergotaminaalcaloide do ergotModerada

    Beta Blockers Although the results of a clinical study did not indicate a safety problem associated with the administration of Dihydroergotamine Mesylate Injection, USP to subjects already receiving propranolol, there have been reports that propranolol may potentiate the vasoconstrictive action of ergotamine by blocking the vasodilating property of epinephrine. (bula de Di-hidroergotamina, Interações medicamentosas)

  • DiclofenacoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Dicloxacilinaantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • DiflunisalAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Digoxinaglicosídeo digitálicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Diltiazembloqueador dos canais de cálcioModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • DisopiramidaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • DoxazosinaalfabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Doxercalciferolanálogo da vitamina DModerada

    Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Doxercalciferol, Advertências e precauções)

  • DronedaronaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Drospirenona + etinilestradiolanticoncepcional oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (bula de Drospirenona + etinilestradiol, Advertências e precauções)

  • Dulaglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • DuloxetinaIRSNModerada

    The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (bula de Duloxetina, Advertências e precauções)

  • EluxadolinaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Beta-Blockers: e.g., metoprolol timolol ↑ beta-blockers Clinical monitoring is recommended and a dosage decrease of the beta blocker may be necessary when these agents are coadministered with GENVOYA. (bula de Elvitegravir + cobicistate + entricitabina + tenofovir, Interações medicamentosas)

  • Empagliflozinainibidor do SGLT2Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Empagliflozina + metforminainibidor do SGLT2Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Enalaprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Enalapril + hidroclorotiazidainibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Epinefrina (adrenalina)simpaticomiméticoModerada

    Such patients may be unresponsive to the usual doses of epinephrine used to treat allergic reactions. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Epoprostenolanálogo de prostaglandinaModerada

    Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (bula de Epoprostenol, Interações medicamentosas)

  • Ergotamina + cafeínaalcaloide do ergotModerada

    The beta-blocker Inderal (propranolol) has been reported to potentiate the vasoconstrictive action of ergotamine tartrate and caffeine tablets by blocking the vasodilating property of epinephrine. (bula de Ergotamina + cafeína, Interações medicamentosas)

  • EscitalopramISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Escitalopram, Advertências e precauções)

  • EsmololbetabloqueadorModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Esomeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Esomeprazol, Advertências e precauções)

  • Espironolactonaantagonista da aldosteronaModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • EtodolacoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Exenatidaagonista do receptor de GLP-1Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Felodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Fenelzinainibidor da MAOModerada

    …hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (bula de Fenelzina, Advertências)

  • FenobarbitalbarbitúricoModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • FenoprofenoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • FenoxibenzaminaalfabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Fenoximetilpenicilina (penicilina V)antibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • FentanilaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Fentermina + topiramatoestimulante do SNCModerada

    Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively. (bula de Fentermina + topiramato, Interações medicamentosas)

  • Fluconazolantifúngico azólicoModerada

    Hydrochlorothiazide In a pharmacokinetic interaction study, coadministration of multiple-dose hydrochlorothiazide to healthy volunteers receiving fluconazole increased plasma concentrations of fluconazole by 40%. (bula de Fluconazol, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (bula de Fludrocortisona, Interações medicamentosas)

  • FluoxetinaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Fluoxetina, Advertências e precauções)

  • FlurbiprofenoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Fluticasona + salmeterolcorticosteroideModerada

    Diuretics: Use with caution. (bula de Fluticasona + salmeterol, Interações medicamentosas)

  • FluvoxaminaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (bula de Fluvoxamina, Advertências e precauções)

  • Formoterolagonista beta-adrenérgicoModerada

    • Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (bula de Formoterol, Interações medicamentosas)

  • FoscarneteantiviralModerada

    When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (bula de Foscarnete, Interações medicamentosas)

  • Fosinoprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Fosinopril + hidroclorotiazidainibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Furosemidadiurético de alçaModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • GlibenclamidasulfonilureiaModerada

    Beta-blockers may further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Glibenclamida + metforminasulfonilureiaModerada

    Beta-blockers may further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • GlimepiridasulfonilureiaModerada

    Beta-blockers may further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • GlipizidasulfonilureiaModerada

    Beta-blockers may further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Glipizida + metforminasulfonilureiaModerada

    Beta-blockers may further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • GlucagonModerada

    Table 4: Clinically Significant Drug Interaction with GVOKE and GVOKE VialDx Beta-Blockers Clincial Impact: Patients taking beta-blockers may have a transient increase in pulse and blood pressure when given GVOKE or GVOKE VialDx. (bula de Glucagon, Interações medicamentosas)

  • Guanfacinaagonista alfa-adrenérgicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • HaloperidolantipsicóticoModerada

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (bula de Haloperidol, Interações medicamentosas)

  • HidralazinavasodilatadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • HidrocodonaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • HidromorfonaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • IbuprofenoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • IbutilidaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • IloperidonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (bula de Iloperidona, Advertências e precauções)

  • Imipraminaantidepressivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (bula de Imipramina, Advertências)

  • Indapamidadiurético tiazídicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • IndometacinaAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Insulina asparteinsulinaModerada

    Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Insulina degludecainsulinaModerada

    Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Insulina detemirinsulinaModerada

    Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Insulina glarginainsulinaModerada

    Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Insulina lisproinsulinaModerada

    Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (bula de Iodeto de potássio, Interações medicamentosas)

  • Ipratrópio + salbutamolanticolinérgicoModerada

    Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (bula de Ipratrópio + salbutamol, Interações medicamentosas)

  • Irbesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Isofluranoanestésico geralModerada

    Concomitant Use with Beta Blockers Concomitant use of beta blockers may exaggerate the cardiovascular effects of inhalational anesthetics, including hypotension and negative inotropic effects. (bula de Isoflurano, Interações medicamentosas)

  • Isradipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • IvabradinaModerada

    The risk of bradycardia increases with concomitant administration of drugs that slow heart rate (e.g., digoxin, amiodarone, beta-blockers). (bula de Ivabradina, Interações medicamentosas)

  • LabetalolbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • LacosamidaanticonvulsivanteModerada

    VIMPAT should also be used with caution in patients on concomitant medications that affect cardiac conduction, including sodium channel blockers, beta-blockers, calcium channel blockers, potassium channel blockers, and medications that prolong the PR interval [see Drug Interactions (7.2) ] . (bula de Lacosamida, Advertências e precauções)

  • LanreotidaModerada

    Bradycardia-Inducing Drugs (e.g., beta-blockers) : Lanreotide Injection may decrease heart rate. (bula de Lanreotida, Interações medicamentosas)

  • Lansoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (bula de Lansoprazol, Advertências e precauções)

  • Ledipasvir + sofosbuvirantiviralModerada

    Patients also taking beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease, may be at increased risk for symptomatic bradycardia with coadministration of amiodarone. (bula de Ledipasvir + sofosbuvir, Advertências e precauções)

  • LevomilnacipranaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (bula de Levomilnaciprana, Advertências e precauções)

  • LevorfanolopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Levossalbutamolagonista beta-adrenérgicoModerada

    In this setting, cardioselective beta-blockers should be considered, although they should be administered with caution. (bula de Levossalbutamol, Interações medicamentosas)

  • Levotiroxinahormônio tireoidianoModerada

    Laboratory Test Interactions Based on reports involving thiazides, bisoprolol fumarate and hydrochlorothiazide tablets may decrease serum levels of protein-bound iodine without signs of thyroid disturbance. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Levotiroxina + liotironinahormônio tireoidianoModerada

    Laboratory Test Interactions Based on reports involving thiazides, bisoprolol fumarate and hydrochlorothiazide tablets may decrease serum levels of protein-bound iodine without signs of thyroid disturbance. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Lidocaínaanestésico localModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Lidocaína + epinefrinaanestésico localModerada

    Such patients may be unresponsive to the usual doses of epinephrine used to treat allergic reactions. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Lidocaína + prilocaínaanestésico localModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Linagliptinainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Linagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • LinezolidaantibióticoModerada

    Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (bula de Linezolida, Advertências e precauções)

  • Liotironinahormônio tireoidianoModerada

    Laboratory Test Interactions Based on reports involving thiazides, bisoprolol fumarate and hydrochlorothiazide tablets may decrease serum levels of protein-bound iodine without signs of thyroid disturbance. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Liraglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Lisinoprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Lisinopril + hidroclorotiazidainibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Lítiomedicamento serotoninérgicoModerada

    Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Lopinavir + ritonavirantirretroviralModerada

    The impact on the PR interval of co-administration of KALETRA with other drugs that prolong the PR interval (including calcium channel blockers, beta-adrenergic blockers, digoxin and atazanavir) has not been evaluated. (bula de Lopinavir + ritonavir, Advertências e precauções)

  • Losartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • LumateperonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (bula de Lumateperona, Advertências e precauções)

  • LurasidonaantipsicóticoModerada

    Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (bula de Lurasidona, Advertências e precauções)

  • Mecamilaminaanti-hipertensivoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • MefloquinaantimaláricoModerada

    There is one report of cardiopulmonary arrest, with full recovery, in a patient who was taking a beta blocker (propranolol) (see PRECAUTIONS, Cardiac Effects ). (bula de Mefloquina, Interações medicamentosas)

  • MeloxicamAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • MetadonaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Metaxalonarelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • MetforminabiguanidaModerada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Metildopaanti-hipertensivoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Metilergometrinaalcaloide do ergotModerada

    Beta-blockers Caution should be exercised when methylergonovine maleate is used concurrently with beta-blockers. (bula de Metilergometrina, Interações medicamentosas)

  • Metilfenidatoestimulante do SNCModerada

    Antihypertensive Drugs: Monitor blood pressure. (bula de Metilfenidato, Interações medicamentosas)

  • Metocarbamolrelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • MetoexitalbarbitúricoModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • MetoprololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Metoprolol + hidroclorotiazidabetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • MexiletinaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • MiglitolantidiabéticoModerada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • MilnacipranaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (bula de Milnaciprana, Advertências e precauções)

  • MirtazapinaantidepressivoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (bula de Mirtazapina, Advertências e precauções)

  • Modafinilaestimulante do SNCModerada

    However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (bula de Modafinila, Advertências e precauções)

  • Moexiprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • MorfinaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (bula de Motixafortida, Advertências e precauções)

  • NabumetonaAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • NadololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Nafcilinaantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • NalbufinaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Naltrexona + bupropionaantagonista opioideModerada

    Drugs Metabolized by CYP2D6: Bupropion inhibits CYP2D6 and can increase concentrations of antidepressants, (e.g., selective serotonin reuptake inhibitors and many tricyclics), antipsychotics (e.g., haloperidol, risperidone and thioridazine), beta-blockers (e.g., metoprolol) and Type 1C antiarrhythmics (e.g., propafenone and flecainide). (bula de Naltrexona + bupropiona, Interações medicamentosas)

  • NaproxenoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • NateglinidameglitinidaModerada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (bula de Niacina (ácido nicotínico), Interações medicamentosas)

  • Nicardipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Nifedipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Nimodipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Nisoldipinobloqueador dos canais de cálcio di-hidropiridínicoModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • NitroglicerinanitratoModerada

    Antihypertensives: Possible additive hypotensive effects. (bula de Nitroglicerina, Interações medicamentosas)

  • Nitroprusseto de sódiovasodilatadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • OctreotidaModerada

    Dosage adjustments of concomitantly used drugs that have bradycardia effects (i.e. beta-blockers) may be necessary [see Drug Interactions (‎7.2) ]. (bula de Octreotida, Advertências e precauções)

  • OlanzapinaantipsicóticoModerada

    …of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (bula de Olanzapina, Advertências e precauções)

  • Olanzapina + fluoxetinaantipsicóticoModerada

    …and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Olanzapina + fluoxetina, Advertências e precauções)

  • OliceridinaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Olmesartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Omeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol, Advertências e precauções)

  • Omeprazol + bicarbonato de sódioinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (bula de Omeprazol + bicarbonato de sódio, Advertências e precauções)

  • Orfenadrinarelaxante muscularModerada

    Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine) - possible increased responsiveness to the muscle relaxant. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Oxacilinaantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • OxaprozinaAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • OxicodonaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • OximetazolinadescongestionanteModerada

    Caution in using drugs such as beta-blockers, anti-hypertensives, and/or cardiac glycosides is advised. (bula de Oximetazolina, Interações medicamentosas)

  • OximorfonaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PaliperidonaantipsicóticoModerada

    Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Paliperidona, Advertências e precauções)

  • Pantoprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Pantoprazol, Advertências e precauções)

  • Paracetamol + codeínaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Paricalcitolanálogo da vitamina DModerada

    The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (bula de Paricalcitol, Advertências e precauções)

  • ParoxetinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (bula de Paroxetina, Advertências e precauções)

  • PasireotidaModerada

    Adjustments in the dose of drugs known to slow the heart rate (e.g., beta-blockers, calcium channel blockers) and correction of electrolyte disturbances may be necessary when initiating or during the course of SIGNIFOR LAR treatment. (bula de Pasireotida, Advertências e precauções)

  • PazopanibeModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (bula de Pazopanibe, Advertências e precauções)

  • Pentazocina + naloxonaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PentoxifilinametilxantinaModerada

    Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (bula de Pentoxifilina, Interações medicamentosas)

  • Perindoprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Petidina (meperidina)opioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Pilocarpinaagonista colinérgicoModerada

    Drug Interactions Pilocarpine should be administered with caution to patients taking beta-adrenergic antagonists because of the possibility of conduction disturbances. (bula de Pilocarpina, Interações medicamentosas)

  • PindololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • PioglitazonatiazolidinedionaModerada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Pioglitazona + glimepiridatiazolidinedionaModerada

    Beta-blockers may further increase the risk of severe hypoglycemia when used concurrently with sulfonylureas. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Pioglitazona + metforminatiazolidinedionaModerada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Piperacilina + tazobactamantibiótico da classe das penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Piridostigminainibidor da colinesteraseModerada

    Use with caution in persons with increased risk of anticholinergic reactions, such as persons with bronchial asthma, chronic obstructive pulmonary disease, bradycardia, cardiac arrhythmias, beta blocker treatment (increased risk of anticholinergic reactions). (bula de Piridostigmina, Advertências e precauções)

  • PiroxicamAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PonesimodeimunossupressorModerada

    Experience with PONVORY is limited in patients receiving concurrent therapy with drugs that decrease heart rate (e.g., beta-blockers, non-dihydropyridine calcium channel blockers - diltiazem and verapamil, and other drugs that may decrease heart rate such as digoxin). (bula de Ponesimode, Advertências e precauções)

  • PrazosinaalfabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Prilocaína + epinefrinaanestésico localModerada

    Such patients may be unresponsive to the usual doses of epinephrine used to treat allergic reactions. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PrimidonaanticonvulsivanteModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • ProcainamidaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • ProclorperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Proclorperazina, Precauções)

  • Prometazina + codeínaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PropafenonaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Propiltiouracilamedicamento antitireoidianoModerada

    Laboratory Test Interactions Based on reports involving thiazides, bisoprolol fumarate and hydrochlorothiazide tablets may decrease serum levels of protein-bound iodine without signs of thyroid disturbance. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PropranololbetabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • QuetiapinaantipsicóticoModerada

    Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (bula de Quetiapina, Advertências e precauções)

  • Quinapril + hidroclorotiazidainibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • QuinidinaantiarrítmicoModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Rabeprazolinibidor da bomba de prótonsModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (bula de Rabeprazol, Advertências e precauções)

  • Ramiprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • RemifentanilaopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • RifampicinaantibióticoModerada

    Bisoprolol Fumarate Concurrent use of rifampin increases the metabolic clearance of bisoprolol fumarate, shortening its elimination half-life. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • RifapentinaantibióticoModerada

    …Anticonvulsants Phenytoin Antimalarials Quinine Azole Antifungals Fluconazole, itraconazole, ketoconazole Antipsychotics Haloperidol Barbiturates Phenobarbital Benzodiazepines Diazepam Beta-Blockers Propranolol Calcium Channel Blockers Diltiazem, nifedipine, verapamil Cardiac Glycoside Preparations Digoxin Corticosteroids Prednisone Fibrates Clofibrate Oral Hypoglycemics… (bula de Rifapentina, Interações medicamentosas)

  • RiociguatevasodilatadorModerada

    Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (bula de Riociguate, Advertências e precauções)

  • RisperidonaantipsicóticoModerada

    Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (bula de Risperidona, Advertências e precauções)

  • RitonavirantirretroviralModerada

    The impact on the PR interval of co-administration of ritonavir with other drugs that prolong the PR interval (including calcium channel blockers, beta-adrenergic blockers, digoxin and atazanavir) has not been evaluated. (bula de Ritonavir, Advertências e precauções)

  • Ropivacaínaanestésico localModerada

    Patients on beta-blockers may not manifest changes in heart rate, but blood pressure monitoring can detect a rise in systolic blood pressure. (bula de Ropivacaína, Advertências e precauções)

  • Sacubitril + valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Salbutamolagonista beta-adrenérgicoModerada

    Beta-blockers: Use with caution. (bula de Salbutamol, Interações medicamentosas)

  • Salmeterolagonista beta-adrenérgicoModerada

    • Beta-blockers: Use with caution. (bula de Salmeterol, Interações medicamentosas)

  • SalsalatoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Saxagliptinainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Saxagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Semaglutidaagonista do receptor de GLP-1Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • SertralinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (bula de Sertralina, Advertências e precauções)

  • Sildenafilainibidor da PDE5Moderada

    Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (bula de Sildenafila, Advertências e precauções)

  • SilodosinaalfabloqueadorModerada

    However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (bula de Silodosina, Advertências e precauções)

  • Sitagliptinainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Sitagliptina + metforminainibidor da DPP-4Moderada

    Antidiabetic drugs (oral agents and insulin) - dosage adjustment of the antidiabetic drug may be required. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Sofosbuvir + velpatasvirantiviralModerada

    Patients also taking beta blockers, or those with underlying cardiac comorbidities and/or advanced liver disease may be at increased risk for symptomatic bradycardia with coadministration of amiodarone. (bula de Sofosbuvir + velpatasvir, Advertências e precauções)

  • SorafenibeModerada

    Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (bula de Sorafenibe, Advertências e precauções)

  • SotalolbetabloqueadorModerada

    Bisoprolol fumarate and hydrochlorothiazide tablets should be used with caution when myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide, are used concurrently. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • SulindacoAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Sumatriptana + naproxenotriptanoModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • SunitinibeModerada

    Initiate and/or adjust antihypertensive therapy as appropriate. (bula de Sunitinibe, Advertências e precauções)

  • Suxametônio (succinilcolina)bloqueador neuromuscularModerada

    Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (bula de Suxametônio (succinilcolina), Advertências e precauções)

  • TacrolimoimunossupressorModerada

    • Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (bula de Tacrolimo, Advertências e precauções)

  • TapentadolopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Telmisartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Telmisartana + anlodipinobloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • TerazosinaalfabloqueadorModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Terbutalinaagonista beta-adrenérgicoModerada

    In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution. (bula de Terbutalina, Precauções)

  • Teriparatidahormônio tireoidianoModerada

    Laboratory Test Interactions Based on reports involving thiazides, bisoprolol fumarate and hydrochlorothiazide tablets may decrease serum levels of protein-bound iodine without signs of thyroid disturbance. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • TestosteronaandrogênioModerada

    In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (bula de Testosterona, Advertências e precauções)

  • Tetrabenazinainibidor do VMAT2Moderada

    Patients receiving catecholamine-depleting drugs, such as reserpine or guanethidine, should be closely monitored because the added beta-adrenergic blocking action of bisoprolol fumarate may produce excessive reduction of sympathetic activity. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Tiamazol (metimazol)medicamento antitireoidianoModerada

    Laboratory Test Interactions Based on reports involving thiazides, bisoprolol fumarate and hydrochlorothiazide tablets may decrease serum levels of protein-bound iodine without signs of thyroid disturbance. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Tirzepatidaagonista do receptor de GLP-1Moderada

    Also, latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Tizanidinarelaxante muscularModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • TobramicinaaminoglicosídeoModerada

    Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (bula de Tobramicina, Interações medicamentosas)

  • TolmetinaAINEModerada

    Nonsteroidal anti-inflammatory drugs - In some patients, the administration of a nonsteroidal anti-inflammatory agent can reduce the diuretic, natriuretic, and antihypertensive effects of loop, potassium sparing, and thiazide diuretics. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • TolvaptanaModerada

    Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (bula de Tolvaptana, Advertências e precauções)

  • TopiramatoanticonvulsivanteModerada

    Hydrochlorothiazide (HCTZ) Topiramate C max and AUC increased when HCTZ was added to immediate-release topiramate. (bula de Topiramato, Interações medicamentosas)

  • Torasemidadiurético de alçaModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Toremifenomodulador seletivo do receptor de estrogênioModerada

    Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (bula de Toremifeno, Interações medicamentosas)

  • TramadolopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Tramadol + paracetamolopioideModerada

    Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Trandolaprilinibidor da ECAModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • TrazodonaantidepressivoModerada

    Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (bula de Trazodona, Advertências e precauções)

  • Trianterenodiurético poupador de potássioModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • TrifluoperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (bula de Trifluoperazina, Precauções)

  • Umeclidínio + vilanterolanticolinérgicoModerada

    • Beta-blockers: Use with caution. (bula de Umeclidínio + vilanterol, Interações medicamentosas)

  • Valbenazinainibidor do VMAT2Moderada

    Patients receiving catecholamine-depleting drugs, such as reserpine or guanethidine, should be closely monitored because the added beta-adrenergic blocking action of bisoprolol fumarate may produce excessive reduction of sympathetic activity. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • Valsartanabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Vardenafilainibidor da PDE5Moderada

    Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (bula de Vardenafila, Interações medicamentosas)

  • VarfarinaanticoagulanteModerada

    There was no effect of bisoprolol fumarate on prothrombin times in patients on stable doses of warfarin. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • VenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (bula de Venlafaxina, Advertências e precauções)

  • Verapamilbloqueador dos canais de cálcioModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • VilazodonaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (bula de Vilazodona, Advertências e precauções)

  • Vitamina DVitaminas e mineraisModerada

    Os diuréticos tiazídicos reduzem a excreção de cálcio; combinado com suplementos de vitamina D e de cálcio, isso pode levar a hipercalcemia, especialmente em idosos. (NIH Office of Dietary Supplements, Vitamin D)

  • VortioxetinaantidepressivoModerada

    Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (bula de Vortioxetina, Advertências e precauções)

  • Zileutonainibidor da CYP1A2Moderada

    Zileuton increases propranolol levels and beta-blocker activity. (bula de Zileutona, Interações medicamentosas)

  • ZiprasidonaantipsicóticoModerada

    Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (bula de Ziprasidona, Advertências e precauções)

Menções leves (57)

  • AclidínioanticolinérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • AmantadinaanticolinérgicoLeve

    Coadministration of 1 Dyazide (triamterene/hydrochlorothiazide) resulted in a higher plasma amantadine hydrochloride concentration in a 61-year old man receiving amantadine hydrochloride 100 mg TID for Parkinson's disease. (bula de Amantadina, Interações medicamentosas)

  • Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (bula de Ambrisentana, Advertências e precauções)

  • AminofilinametilxantinaLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Azelastina + fluticasonaanti-histamínicoLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • BeclometasonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • BetametasonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Bosentanaindutor da CYP3A4Leve

    Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (bula de Bosentana, Advertências e precauções)

  • BudesonidacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • CálcioVitaminas e mineraisLeve

    Os diuréticos tiazídicos reduzem a excreção de cálcio, de modo que um consumo alto de cálcio pode elevar o cálcio no sangue. (NIH Office of Dietary Supplements, Calcium)

  • CiclesonidacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • ClobetasolcorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (bula de Corticotropina, Interações medicamentosas)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (bula de Dasatinibe, Advertências e precauções)

  • DeflazacortecorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Desogestrel + etinilestradiolanticoncepcional oralLeve

    If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (bula de Desogestrel + etinilestradiol, Advertências)

  • DesonidacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • DexametasonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Dextroanfetaminaestimulante do SNCLeve

    Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (bula de Dextroanfetamina, Interações medicamentosas)

  • Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (bula de Docetaxel, Advertências e precauções)

  • EfedrinasimpaticomiméticoLeve

    Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (bula de Efedrina, Interações medicamentosas)

  • In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Estrogênios esterificados + metiltestosterona, Advertências)

  • Febuxostateinibidor da xantina oxidaseLeve

    In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, ULORIC does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology (12.3) ]. (bula de Febuxostate, Interações medicamentosas)

  • Finasteridainibidor da 5-alfa-redutaseLeve

    …PROSCAR was concomitantly used in clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines,… (bula de Finasterida, Interações medicamentosas)

  • FingolimodeimunossupressorLeve

    Drugs That Slow Heart Rate or Atrioventricular Conduction (e.g., beta blockers or diltiazem) Experience with GILENYA in patients receiving concurrent therapy with drugs that slow the heart rate or AV conduction (e.g., beta blockers, digoxin, or heart rate-slowing calcium channel blockers, such as diltiazem or verapamil) is limited. (bula de Fingolimode, Interações medicamentosas)

  • FlunisolidacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • FluocinonidacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • FluticasonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (bula de Gliconato de cálcio, Interações medicamentosas)

  • HalobetasolcorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • HidrocortisonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (bula de Icatibanto, Interações medicamentosas)

  • Imatinibeinibidor da CYP3A4Leve

    Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (bula de Imatinibe, Advertências e precauções)

  • IpratrópioanticolinérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Isoprenalina (isoproterenol)agonista beta-adrenérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (bula de Macitentana, Advertências e precauções)

  • MagnésioVitaminas e mineraisLeve

    O uso prolongado de diuréticos de alça e tiazídicos aumenta a perda de magnésio na urina. (NIH Office of Dietary Supplements, Magnesium)

  • MetilprednisolonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • MetiltestosteronaandrogênioLeve

    In addition to discontinuation of the drug, diuretic therapy may be required. (bula de Metiltestosterona, Advertências)

  • Milrinonainibidor da PDE3Leve

    …been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (bula de Milrinona, Interações medicamentosas)

  • Mirabegronaagonista beta-adrenérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • MometasonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Nortriptilinaantidepressivo tricíclicoLeve

    The antihypertensive action of guanethidine and similar agents may be blocked. (bula de Nortriptilina, Advertências)

  • Olopatadina + mometasonaanti-histamínicoLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PerfenazinaantipsicóticoLeve

    Drug Interactions Metabolism of a number of medications, including antipsychotics, antidepressants, β-blockers, and antiarrhythmics, occurs through the cytochrome P450 2D6 isoenzyme (debrisoquine hydroxylase). (bula de Perfenazina, Interações medicamentosas)

  • PotássioVitaminas e mineraisLeve

    Os diuréticos de alça e tiazídicos aumentam a perda de potássio; a suplementação às vezes é prescrita junto com eles. (NIH Office of Dietary Supplements, Potassium)

  • PrednisolonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PrednisonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • Protriptilinaantidepressivo tricíclicoLeve

    Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (bula de Protriptilina, Advertências)

  • TeofilinametilxantinaLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • TerbinafinaantifúngicoLeve

    Drugs predominantly metabolized by the CYP450 2D6 isozyme include the following drug classes: tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone) and monoamine oxidase inhibitors Type B. (bula de Terbinafina, Interações medicamentosas)

  • TimololbetabloqueadorLeve

    Bisoprolol fumarate and hydrochlorothiazide tablets should not be combined with other beta-blocking agents. (bula de Bisoprolol + hidroclorotiazida, Interações medicamentosas)

  • TiotrópioanticolinérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • TriancinolonacorticosteroideLeve

    Corticosteroids, ACTH - Intensified electrolyte depletion, particularly hypokalemia. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • UmeclidínioanticolinérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • Vibegronaagonista beta-adrenérgicoLeve

    A beta 2 agonist (bronchodilator) should be made available. (bula de Bisoprolol + hidroclorotiazida, Advertências)

  • ZincoVitaminas e mineraisLeve

    Os diuréticos tiazídicos aumentam a perda de zinco na urina com o uso prolongado. (NIH Office of Dietary Supplements, Zinc)

Nenhuma interação significativa relatada (3)

  • Cimetidinabloqueador H2Sem interação

    Pharmacokinetic studies document no clinically relevant interactions with other agents given concomitantly, including thiazide diuretics and cimetidine. (bula de Bisoprolol + hidroclorotiazida, Precauções)

  • PamidronatobisfosfonatoSem interação

    Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (bula de Pamidronato, Interações medicamentosas)

  • Ropinirolagonista da dopaminaSem interação

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (bula de Ropinirol, Interações medicamentosas)

Verifique Bisoprolol + hidroclorotiazida com tudo o que você toma. Adicione sua lista completa; todos os pares são verificados de uma vez.

Abrir no verificador

Não é aconselhamento médico. A gravidade reflete a redação da bula, não as suas circunstâncias. Um alerta “grave” pode ser rotina sob supervisão, e um “leve” pode ser importante em doses altas. Pergunte a um farmacêutico.