Interação entre Captopril e Sumatriptana + naproxeno
Captopril e Sumatriptana + naproxeno: ambas as bulas profissionais descrevem uma interação que geralmente exige monitoramento, alteração da dose ou espaçamento entre as doses.
Geralmente controlável com monitoramento ou alteração da dose. Informe ao seu farmacêutico que você toma os dois.
O que dizem as bulas da FDA
Da bula de Captopril · em vigor desde 2026-09-14
Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including captopril, may result in deterioration…
Monitor renal function periodically in patients receiving captopril and NSAID therapy.
The antihypertensive effect of ACE inhibitors, including captopril, may be attenuated by NSAIDs.
Da bula de Sumatriptana + naproxeno (Sumatriptan and Naproxen Sodium) · em vigor desde 2025-10-30
Patients at greatest risk of this reaction are those with impaired renal function, dehydration, hypovolemia, heart failure, liver dysfunction, salt depletion, those taking diuretics and angiotensin-converting enzyme (ACE) inhibitors or ARBs, and the elderly.
ACE Inhibitors and ARBs: Concomitant use with sumatriptan and naproxen sodium tablets in elderly, volume depleted, or those with renal impairment may result in deterioration of renal function.
Monitor patients to assure diuretic efficacy including antihypertensive effects.
In patients who are elderly, volume-depleted (including those on diuretic therapy), or have renal impairment, coadministration of an NSAID with ACE inhibitors or ARBs may result in deterioration of renal function, including possible acute renal failure.
Intervention: During concomitant use of sumatriptan and naproxen sodium tablets and ACE-inhibitors, ARBs, or beta-blockers, monitor blood pressure to ensure that the desired blood pressure is obtained [see Warnings and Precautions (5.8)] .
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Abrir no verificadorNão é aconselhamento médico. Interaction Checker cita o texto das bulas da FDA e fichas informativas do NIH. A importância de uma interação para você depende das doses, dos horários, da função renal e hepática e de outras condições de saúde. Confirme com um farmacêutico ou com o prescritor.