Interação entre Etonogestrel + etinilestradiol e Noretisterona

CONTRAINDICATIONS Progestin-only oral contraceptives (POPs) should not be used by women who currently have the following conditions: • Known or suspected pregnancy • Known or suspected carcinoma of the breast.

Norethindrone tablets do not contain estrogen and, therefore, this insert does not discuss the serious health risks that have been associated with the estrogen component of combined oral contraceptives (COCs).

The healthcare professional is referred to the prescribing information of combined oral contraceptives for a discussion of those risks.

The relationship between progestin-only oral contraceptives and these risks is not fully defined.

Irregular Genital Bleeding Irregular menstrual patterns are common among women using progestin-only oral contraceptives.

WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use.

Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use.

…incidence for new users of Etonogestrel/Ethinyl Estradiol Vaginal Ring to be 11.4 events per 10,000 WY, for new users of a levonorgestrel (LNG)-containing COC 9.2 events per 10,000 WY, and for users of other COCs available during the course of the study Includes low-dose COCs containing the following progestins: norgestimate, norethindrone, or levonorgestrel.

Consider an alternate contraceptive method for women with uncontrolled dyslipidemia.

In these studies, which were required or sponsored by regulatory agencies, Etonogestrel/Ethinyl Estradiol Vaginal Ring users had a risk of VTE similar to Combined Oral Contraceptives (COCs) users (see Table 1 for adjusted hazard ratios).