Fludrokortizon etkileşimleri

kortikosteroid sınıfından Fludrokortizon (Florinef) için dizinlediğimiz FDA etiketlerinde ve bilgi sayfalarında 374 belgelenmiş etkileşim var: 56 majör, 268 orta, 50 minör ve bir etiketin anlamlı etkileşim olmadığını bildirdiği 0 çift. Aşağıdaki her kayıt, dayandığı cümleyi alıntılar. Bu ilaç sayfası bir başlangıç noktasıdır; sizin durumunuz için verilmiş bir hüküm değildir.

Etikete göre etkileşimler

Majör etkileşimler (56)

  • AbataseptimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • AbirateronCYP2D6 inhibitörüMajör

    At the primary analysis, increased incidences of fractures (28.6% vs 11.4%) and deaths (38.5% vs 35.5%) have been observed in patients who received abiraterone acetate plus a corticosteroid in combination with radium Ra 223 dichloride compared to patients who received placebo in combination with abiraterone acetate plus a corticosteroid. (Abirateron etiketi, Uyarılar ve önlemler)

  • AbrositinibJAK inhibitörüMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • AdalimumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • AdrenalinsempatomimetikMajör

    …Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline Epinephrine should not be used to counteract circulatory collapse or hypotension caused by phenothiazines, as a reversal of the pressor effects of epinephrine… (Adrenalin etiketi, İlaç etkileşimleri)

  • AksitinibMajör

    Withhold INLYTA and avelumab or pembrolizumab, initiate corticosteroid therapy as needed, and/or permanently discontinue the combination for severe or life-threatening hepatotoxicity. (Aksitinib etiketi, Uyarılar ve önlemler)

  • AlemtuzumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Arformoterolbeta adrenerjik agonistMajör

    Use of a LABA, including arformoterol tartrate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma. (Arformoterol etiketi, Kontrendikasyonlar)

  • Arsenik trioksitQT aralığını uzatan ilaçMajör

    If differentiation syndrome is suspected, immediately initiate high-dose corticosteroids and hemodynamic monitoring until resolution. (Arsenik trioksit etiketi, Kutulu uyarı)

  • AtazanavirantiretroviralMajör

    Coadministration of fluticasone propionate and REYATAZ with ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects [see Warnings and Precautions (5.1) ] . (Atazanavir etiketi, İlaç etkileşimleri)

  • AzatioprinimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • BarisitinibJAK inhibitörüMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Dimetil fumaratimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Dosetaksel etiketi, Uyarılar ve önlemler)

  • …(5.7) , Drug Interactions (7) , and Clinical Pharmacology (12.3) ]: Anticonvulsants: carbamazepine, oxcarbazepine, phenobarbital, phenytoin Antimycobacterials: rifampin, rifapentine Glucocorticoid (systemic): dexamethasone (more than a single-dose) Herbal Products: St John's wort ( Hypericum perforatum ) Proton Pump Inhibitors: e.g., dexlansoprazole, esomeprazole,… (Emtrisitabin, rilpivirin ve tenofovir etiketi, Kontrendikasyonlar)

  • EtanerseptimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • EverolimusimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • FingolimodimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Formoterolbeta adrenerjik agonistMajör

    Use of a LABA, including formoterol fumarate inhalation solution, without an inhaled corticosteroid is contraindicated in patients with asthma [see Warnings and Precautions (5.1) ]. (Formoterol etiketi, Kontrendikasyonlar)

  • FosamprenavirantiretroviralMajör

    Coadministration of fluticasone and fosamprenavir calcium/ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (Fosamprenavir etiketi, İlaç etkileşimleri)

  • GuselkumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • İnfliksimabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Kandesartananjiyotensin II reseptör blokeri (ARB)Majör

    Triple combination of candesartan cilexetil with an ACE-inhibitor and a mineralocorticoid receptor antagonist is generally not recommended. (Kandesartan etiketi, İlaç etkileşimleri)

  • Ketokonazolazol antifungalMajör

    Fluticasone: Coadministration of fluticasone propionate and ketoconazole is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects. (Ketokonazol etiketi, İlaç etkileşimleri)

  • KladribinantimetabolitMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • LeflunomidimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • LovastatinstatinMajör

    Moreover, cholesterol and other products of the cholesterol biosynthesis pathway are essential components for fetal development, including synthesis of steroids and cell membranes. (Lovastatin etiketi, Kontrendikasyonlar)

  • MerkaptopürinantimetabolitMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • MetotreksatimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • MifepristonCYP3A4 inhibitörüMajör

    WARNING: TERMINATION OF PREGNANCY Mifepristone is a potent antagonist of progesterone and cortisol via the progesterone and glucocorticoid (GR-II) receptors, respectively. (Mifepriston etiketi, Kutulu uyarı)

  • MikofenolatimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • MitotanCYP3A4 indükleyicisiMajör

    If shock, severe trauma or infection occurs or develops, temporarily discontinue LYSODREN and administer exogenous steroids. (Mitotan etiketi, Kutulu uyarı)

  • MoeksiprilACE inhibitörüMajör

    None of the cases were considered life-threatening and all resolved either without treatment or with medication (antihistamines or glucocorticoids). (Moeksipril etiketi, Uyarılar)

  • NatalizumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • …2 , Drug Interactions (7.3) ] ) • Immunosuppressants: voclosporin • Microsomal triglyceride transfer protein inhibitor: lomitapide • Migraine medications: eletriptan, ubrogepant • Mineralocorticoid receptor antagonists: finerenone • Non-opioid analgesic (selective blocker of Na v 1.8 sodium channels): suzetrigine • Opioid antagonists: naloxegol • PDE5 inhibitor:… (Nirmatrelvir ve ritonavir etiketi, Kontrendikasyonlar)

  • OkrelizumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Pimekrolimuskalsinörin inhibitörüMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • PonesimodimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • RilpivirinantiretroviralMajör

    Antimycobacterials Rifampin Rifapentine Glucocorticoid (systemic) Dexamethasone (more than a single-dose treatment) Herbal Products St. (Rilpivirin etiketi, Kontrendikasyonlar)

  • RitlesitinibJAK inhibitörüMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • RituksimabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Salmeterolbeta adrenerjik agonistMajör

    WARNING: ASTHMA-RELATED DEATH Long-acting beta 2 -adrenergic agonists (LABA), such as salmeterol, the active ingredient in SEREVENT DISKUS, as monotherapy (without inhaled corticosteroids [ICS]) increase the risk of asthma-related death. (Salmeterol etiketi, Kutulu uyarı)

  • SekukinumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • SiklofosfamidimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • SiklosporinimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • SirolimusimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • Intervention: Carefully adjust glucocorticoid dosing in pediatric patients receiving glucocorticoid treatments to avoid both hypoadrenalism and an inhibitory effect on growth. (Somatropin etiketi, İlaç etkileşimleri)

  • TakrolimusimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • TeriflunomidimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • TofasitinibimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • TosilizumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • TrandolaprilACE inhibitörüMajör

    Two of the four cases were life-threatening and resolved without treatment or with medication (corticosteroids). (Trandolapril etiketi, Uyarılar)

  • TretinoinretinoidMajör

    At first signs or symptoms of this syndrome, immediately initiate high-dose corticosteroid therapy and hemodynamic monitoring until resolution of signs and symptoms. (Tretinoin etiketi, Kutulu uyarı)

  • Umeklidinyum ve vilanterolantikolinerjikMajör

    • use of a long-acting beta 2 -adrenergic agonist (LABA), including vilanterol, one of the active ingredients in Umeclidinium and Vilanterol ELLIPTA, without an inhaled corticosteroid (ICS), in patients with asthma [see Warnings and Precautions ( 5.1 )] . (Umeklidinyum ve vilanterol etiketi, Kontrendikasyonlar)

  • UpadasitinibimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

  • UstekinumabimmünosüpresanMajör

    Chicken pox and measles, for example, can have a more serious or even fatal course in children on immunosuppressant corticosteroids. (Fludrokortizon etiketi, Uyarılar)

Orta düzey etkileşimler (268)

  • Patients receiving concomitant corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs) or anti-angiogenic agents, or patients with increasing age or who have an underlying history of gastrointestinal ulceration, underlying diverticular disease or bowel metastases may be at increased risk of perforation. (Afatinib etiketi, Uyarılar ve önlemler)

  • AkarbozantidiyabetikOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • AklidinyumantikolinerjikOrta

    Sympathomimetics, Methylxanthines, Steroids In clinical studies, concurrent administration of aclidinium bromide and other drugs commonly used in the treatment of COPD including sympathomimetics (short-acting beta 2 agonists), methylxanthines, and oral and inhaled steroids showed no increases in adverse drug reactions. (Aklidinyum etiketi, İlaç etkileşimleri)

  • Risk of Neurologic Symptoms: Neurocysticercosis patients may experience cerebral hypertensive episodes, seizures or focal neurologic deficits after initiation of therapy; begin appropriate steroid and anticonvulsant therapy. (Albendazol etiketi, Uyarılar ve önlemler)

  • AlendronatbifosfonatOrta

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (Alendronat etiketi, Uyarılar ve önlemler)

  • AliskirenantihipertansifOrta

    Patients who experience these effects, even without respiratory distress, require prolonged observation and appropriate monitoring measures since treatment with antihistamines and corticosteroids may not be sufficient to prevent respiratory involvement. (Aliskiren etiketi, Uyarılar ve önlemler)

  • AlogliptinDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Alogliptin ve metforminDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • If a SCAR is not confirmed, VIJOICE may require dose modifications, topical or systemic corticosteroids, or oral antihistamine treatment as described in Table 4 [see Dosage and Administration (2.5)] . (Alpelisib etiketi, Uyarılar ve önlemler)

  • Amfoterisin BantifungalOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Amiloridpotasyum tutucu diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • ApiksabanantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • ArgatrobanantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Asetazolamidkarbonik anhidraz inhibitörüOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • AspirinNSAİİOrta

    Aspirin — increased ulcerogenic effect; decreased pharmacologic effect of aspirin. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Aspirin ve dipiridamolantitrombosit ilaçOrta

    Aspirin — increased ulcerogenic effect; decreased pharmacologic effect of aspirin. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • BalsalazidsalisilatOrta

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • BeklometazonkortikosteroidOrta

    Although QVAR REDIHALER may provide control of asthmatic symptoms during these episodes, in recommended doses it supplies less than normal physiological amounts of glucocorticoid systemically and does NOT provide the mineralocorticoid that is necessary for coping with these emergencies. (Beklometazon etiketi, Uyarılar ve önlemler)

  • BeksagliflozinSGLT2 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Belladonna ve afyon etiketi, Uyarılar ve önlemler)

  • Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Consider measures to prevent severe reactions, including antihistamines, antipyretics and corticosteroids in subsequent cycles in patients who have experienced Grade 1 or 2 infusion reactions. (Bendamustin etiketi, Uyarılar ve önlemler)

  • • Reduction in Corticosteroid Dosage: Do not discontinue systemic or inhaled corticosteroids abruptly upon initiation of therapy with FASENRA. (Benralizumab etiketi, Uyarılar ve önlemler)

  • BikalutamidandrojenOrta

    Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) ↓ lenacapavir (dexamethasone) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (Biktegravir, emtrisitabin ve tenofovir alafenamid etiketi, İlaç etkileşimleri)

  • Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • BivalirudinantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Bizmut subsalisilatsalisilatOrta

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Management of orthostatic/postural hypotension may include adjustment of antihypertensive medications, hydration, and administration of mineralocorticoids and/or sympathomimetics. (Bortezomib etiketi, Uyarılar ve önlemler)

  • BudesonidkortikosteroidOrta

    Although PULMICORT FLEXHALER may provide control of asthma symptoms during these episodes, in recommended doses it supplies less than normal physiological amounts of glucocorticoid systemically and does NOT provide the mineralocorticoid activity that is necessary for coping with these emergencies. (Budesonid etiketi, Uyarılar ve önlemler)

  • Budesonid ve formoterolkortikosteroidOrta

    In this situation, the patient requires immediate re-evaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of budesonide and formoterol fumarate dihydrate with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (Budesonid ve formoterol etiketi, Uyarılar ve önlemler)

  • Bumetanidkıvrım (loop) diüretiğiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • BuprenorfinopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Buprenorfin etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Buprenorfin ve nalokson etiketi, Uyarılar ve önlemler)

  • BupropionantidepresanOrta

    …risk of seizure: concomitant use of other medications that lower the seizure threshold (e.g., other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, and systemic corticosteroids), metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia), or use of illicit drugs (e.g., cocaine) or abuse or misuse… (Bupropion etiketi, Uyarılar ve önlemler)

  • Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Aspirin — increased ulcerogenic effect; decreased pharmacologic effect of aspirin. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Aspirin — increased ulcerogenic effect; decreased pharmacologic effect of aspirin. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • ButorfanolopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Butorfanol etiketi, Uyarılar)

  • DabigatranantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • DanazolandrojenOrta

    Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • DapagliflozinSGLT2 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Dapagliflozin ve metforminSGLT2 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • DaptomisinantibiyotikOrta

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomisin etiketi, Uyarılar ve önlemler)

  • DarunavirantiretroviralOrta

    Corticosteroids: dexamethasone (systemic) ↓ darunavir Co-administration of PREZISTA/ritonavir with systemic dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic effect and development of resistance to darunavir. (Darunavir etiketi, İlaç etkileşimleri)

  • Darunavir ve kobisistatantiretroviralOrta

    Corticosteroids: dexamethasone (systemic) Corticosteroids primarily metabolized by CYP3A: e.g. betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone ↓ darunavir ↓ cobicistat ↑ corticosteroids Co-administration with systemic dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic… (Darunavir ve kobisistat etiketi, İlaç etkileşimleri)

  • Deferasiroksdemir takviyesiOrta

    The risk of GI hemorrhage may be increased when administering Exjade in combination with drugs that have ulcerogenic or hemorrhagic potential, such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, oral bisphosphonates, or anticoagulants. (Deferasiroks etiketi, Uyarılar ve önlemler)

  • Other risk factors for the development of ONJ include immunosuppressive therapy, treatment with angiogenesis inhibitors, systemic corticosteroids, diabetes, and gingival infections. (Denosumab etiketi, Uyarılar ve önlemler)

  • Desogestrel ve etinilestradioloral kontraseptifOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • DiflunisalNSAİİOrta

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Digoksindijital glikozidiOrta

    Digitalis glycosides — enhanced possibility of arrhythmias or digitalis toxicity associated with hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • DiklofenakNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Diklofenak etiketi, Uyarılar ve önlemler)

  • Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Diklofenak ve misoprostol etiketi, Uyarılar ve önlemler)

  • DisikloverinantikolinerjikOrta

    Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corticosteroids. (Disikloverin etiketi, İlaç etkileşimleri)

  • Drospirenon ve etinilestradioloral kontraseptifOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • DulaglutidGLP-1 reseptör agonistiOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Eosinophilic Conditions: Be alert to vasculitic rash, worsening pulmonary symptoms, cardiac complications, kidney injury and/or neuropathy, especially upon reduction of oral corticosteroids. (Dupilumab etiketi, Uyarılar ve önlemler)

  • EdoksabanantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • EksenatidGLP-1 reseptör agonistiOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Although other risk factors were present in some cases (such as corticosteroid use, exposure to radiation), a possible risk attributable to treatment with ivacaftor cannot be excluded. (Eleksakaftor, tezakaftor ve ivakaftor etiketi, Uyarılar ve önlemler)

  • Corticosteroids: e.g., betamethasone budesonide ciclesonide dexamethasone fluticasone methylprednisolone mometasone prednisone triamcinolone ↓ elvitegravir ↓ cobicistat ↑ corticosteroids Coadministration with oral dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic effect and development of resistance to elvitegravir. (Elvitegravir, kobisistat, emtrisitabin ve tenofovir etiketi, İlaç etkileşimleri)

  • EmpagliflozinSGLT2 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Empagliflozin ve metforminSGLT2 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Enalapril ve hidroklorotiyazidACE inhibitörüOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • EnoksaparinantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Eplerenonaldosteron antagonistiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Patients receiving concomitant anti-angiogenic agents, corticosteroids, NSAIDs, or taxane-based chemotherapy, or who have prior history of peptic ulceration or diverticular disease may be at increased risk of perforation [see Adverse Reactions (6.1 , 6.2) ]. (Erlotinib etiketi, Uyarılar ve önlemler)

  • Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • EstradiolöstrojenOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Estradiol ve dienogestoral kontraseptifOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Etakrinik asitkıvrım (loop) diüretiğiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • EtodolakNSAİİOrta

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (Etodolak etiketi, Uyarılar)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • EtravirinantiretroviralOrta

    Corticosteroid : dexamethasone (systemic) ↓ etravirine Systemic dexamethasone induces CYP3A and can decrease etravirine plasma concentrations. (Etravirin etiketi, İlaç etkileşimleri)

  • Fampridin (dalfampridin)potasyum takviyesiOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • FenilefrindekonjestanOrta

    Agonistic Effects (increase in BIORPHEN blood pressure effect) can occur with monoamine oxidase inhibitors (MAOI), oxytocin and oxytocic drugs, tricyclic antidepressants, angiotensin and aldosterone, atropine, steroids, norepinephrine transporter inhibitors, ergot alkaloids. (Fenilefrin etiketi, İlaç etkileşimleri)

  • FenitoinantikonvülsanOrta

    Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • FenobarbitalbarbitüratOrta

    Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • FenoprofenNSAİİOrta

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Fenoprofen etiketi, Uyarılar ve önlemler)

  • FentanilopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Fentanil etiketi, Uyarılar ve önlemler)

  • FlunisolidkortikosteroidOrta

    Pregnancy As with other corticosteroids, flunisolide has been shown to be teratogenic and fetotoxic in rabbits and rats at oral doses of 40 and 200 mcg/kg/day, respectively (approximately 2 and 4 times, respectively, the maximum recommended daily intranasal dose in adults on a mg/m 2 basis). (Flunisolid etiketi, Önlemler)

  • FluosinonidkortikosteroidOrta

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic absorption of topical corticosteroids. (Fluosinonid etiketi, Uyarılar ve önlemler)

  • FlurbiprofenNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking, use of alcohol, older age, and poor general health status. (Flurbiprofen etiketi, Uyarılar ve önlemler)

  • FlutamidandrojenOrta

    Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • FlutikazonkortikosteroidOrta

    Although Fluticasone Propionate DISKUS may control asthma symptoms during these episodes, in recommended doses it supplies less than normal physiological amounts of glucocorticoid systemically and does NOT provide the mineralocorticoid activity that is necessary for coping with these emergencies. (Flutikazon etiketi, Uyarılar ve önlemler)

  • Flutikazon ve salmeterolkortikosteroidOrta

    In this situation, the patient requires immediate reevaluation with reassessment of the treatment regimen, giving special consideration to the possible need for replacing the current strength of Fluticasone Propionate/Salmeterol MDPI with a higher strength, adding additional inhaled corticosteroid, or initiating systemic corticosteroids. (Flutikazon ve salmeterol etiketi, Uyarılar ve önlemler)

  • FondaparinuksantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • FosfenitoinantikonvülsanOrta

    Other Corticosteroids, doxycycline, estrogens, furosemide, oral contraceptives, paroxetine, quinidine, rifampin, sertraline, theophylline, and vitamin D Drugs whose level is decreased by phenytoin Anticoagulants Apixaban, dabigatran, edoxaban, rivaroxaban Antiepileptic drugs The effect of phenytoin on phenobarbital, valproic acid and sodium valproate serum levels… (Fosfenitoin etiketi, İlaç etkileşimleri)

  • Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • FulvestrantöstrojenOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Furosemidkıvrım (loop) diüretiğiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • GlibenklamidsülfonilüreOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Glibenklamid ve metforminsülfonilüreOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • GlimepiridsülfonilüreOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • GlipizidsülfonilüreOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Glipizid ve metforminsülfonilüreOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Corticosteroids, valproic acid, or haloperidol : May increase plasma ammonia level; monitor ammonia levels closely. (Gliserol fenilbütirat etiketi, İlaç etkileşimleri)

  • HalobetazolkortikosteroidOrta

    Use of more than one corticosteroid-containing product at the same time may increase the total systemic exposure to topical corticosteroids. (Halobetazol etiketi, Uyarılar ve önlemler)

  • HaloperidolantipsikotikOrta

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (Haloperidol etiketi, İlaç etkileşimleri)

  • HeparinantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • HidralazinvazodilatörOrta

    Long-term treatment with steroids may be necessary (see PRECAUTIONS, Laboratory Tests ). (Hidralazin etiketi, Uyarılar)

  • Hidroklorotiyazidtiyazid diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • HidrokodonopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Hidrokodon etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Hidrokodon ve homatropin etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Hidrokodon ve ibuprofen etiketi, Uyarılar)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Hidrokodon ve klorfeniramin etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Hidrokodon ve parasetamol etiketi, Uyarılar)

  • HidrokortizonkortikosteroidOrta

    Average and large doses of hydrocortisone or cortisone can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium. (Fludrokortizon etiketi, Uyarılar)

  • HidromorfonopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Hidromorfon etiketi, Uyarılar ve önlemler)

  • İbandronatbifosfonatOrta

    …osteonecrosis of the jaw include invasive dental procedures (e.g., tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (e.g., chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (e.g., periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection, ill-fitting… (İbandronat etiketi, Uyarılar ve önlemler)

  • İbuprofenNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (İbuprofen etiketi, Uyarılar ve önlemler)

  • Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (İbuprofen ve famotidin etiketi, Uyarılar ve önlemler)

  • İmatinibCYP3A4 inhibitörüOrta

    If either is abnormal, consider prophylactic use of systemic steroids (1-2 mg/kg) for one to two weeks concomitantly with Gleevec at the initiation of therapy. (İmatinib etiketi, Uyarılar ve önlemler)

  • İndapamidtiyazid diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İndometazinNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (İndometazin etiketi, Uyarılar ve önlemler)

  • İnsülin aspartinsülinOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İnsülin degludekinsülinOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İnsülin detemirinsülinOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İnsülin glarjininsülinOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İnsülin lisproinsülinOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İrbesartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • İvakaftorCYP3A4 inhibitörüOrta

    Although other risk factors were present in some cases (such as corticosteroid use and/or exposure to radiation), a possible risk attributable to KALYDECO cannot be excluded. (İvakaftor etiketi, Uyarılar ve önlemler)

  • Oral hydration, recumbency, intravenous normal saline, and/or parenteral corticosteroids have been used to treat postural hypotension. (İvermektin etiketi, Uyarılar)

  • KanagliflozinSGLT2 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Kandesartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • KetoprofenNSAİİOrta

    PRECAUTIONS General Ketoprofen Capsules, USP cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. (Ketoprofen etiketi, Uyarılar ve önlemler)

  • KetorolakNSAİİOrta

    In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (Ketorolak etiketi, Uyarılar ve önlemler)

  • Kinapril ve hidroklorotiyazidACE inhibitörüOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Klorotiyazidtiyazid diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Klortalidontiyazid diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • KodeinopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Kodein etiketi, Uyarılar ve önlemler)

  • Kokainlokal anestezikOrta

    Plasma cholinesterase activity may be decreased by chronic administration of certain monoamine oxidase inhibitors, oral contraceptives, glucocorticoids, antimyasthenics (neostigmine), cyclophosphamide, and possibly thiotepa. (Kokain etiketi, İlaç etkileşimleri)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • LenakapavirantiretroviralOrta

    Corticosteroids (systemic): cortisone/hydrocortisone dexamethasone ↑ corticosteroids (systemic) Concomitant administration with systemic corticosteroids whose exposures are significantly increased by CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. (Lenakapavir etiketi, İlaç etkileşimleri)

  • LevofloksasinflorokinolonOrta

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients usually over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Levofloksasin etiketi, Uyarılar ve önlemler)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • LevorfanolopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Levorfanol etiketi, Uyarılar)

  • Levosalbutamolbeta adrenerjik agonistOrta

    If the patient needs more doses of XOPENEX HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (Levosalbutamol etiketi, Uyarılar ve önlemler)

  • Levotiroksintiroid hormonuOrta

    Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (Levotiroksin etiketi, Uyarılar ve önlemler)

  • Levotiroksin ve liyotironintiroid hormonuOrta

    The therapy of myxedema coma requires simultaneous administration of glucocorticoids (See DOSAGE AND ADMINISTRATION). (Levotiroksin ve liyotironin etiketi, Önlemler)

  • LinagliptinDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Linagliptin ve metforminDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • LiraglutidGLP-1 reseptör agonistiOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Liyotironintiroid hormonuOrta

    Acute Adrenal Crisis in Patients with Concomitant Adrenal Insufficiency Thyroid hormone increases metabolic clearance of glucocorticoids. (Liyotironin etiketi, Uyarılar ve önlemler)

  • Lopinavir ve ritonavirantiretroviralOrta

    …Nasal/Ophthalmic Corticosteroids: e.g., betamethasone budesonide ciclesonide dexamethasone fluticasone methylprednisolone mometasone prednisone triamcinolone ↓ lopinavir ↑ glucocorticoids Coadministration with oral dexamethasone or other systemic corticosteroids that induce CYP3A may result in loss of therapeutic effect and development of resistance to lopinavir. (Lopinavir ve ritonavir etiketi, İlaç etkileşimleri)

  • Losartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • In patients who experience mild or moderate IRRs, consider premedications, including antihistamines, corticosteroids, and antipyretics. (Margetuksimab etiketi, Uyarılar ve önlemler)

  • MedroksiprogesteronprogestinOrta

    MPA Injectable Suspension, USP can pose an additional risk in patients with risk factors for osteoporosis (e.g., metabolic bone disease, chronic alcohol and/or tobacco use, anorexia nervosa, strong family history of osteoporosis or chronic use of drugs that can reduce bone mass such as anticonvulsants or corticosteroids). (Medroksiprogesteron etiketi, Uyarılar ve önlemler)

  • Mefenamik asitNSAİİOrta

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy, concomitant use of oral corticosteroids, anti-platelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs), smoking, use of alcohol, older age, and poor general health status. (Mefenamik asit etiketi, Uyarılar ve önlemler)

  • MegestrolprogestinOrta

    Laboratory evaluation for adrenal insufficiency and consideration of replacement or stress doses of a rapidly acting glucocorticoid are strongly recommended in such patients. (Megestrol etiketi, Uyarılar ve önlemler)

  • MeloksikamNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Meloksikam etiketi, Uyarılar ve önlemler)

  • Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Decrease corticosteroids gradually, if appropriate. (Mepolizumab etiketi, Uyarılar ve önlemler)

  • MesalazinsalisilatOrta

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • MetadonopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Metadon etiketi, Uyarılar ve önlemler)

  • Metazolamidkarbonik anhidraz inhibitörüOrta

    Drug Interactions Methazolamide should be used with caution in patients on steroid therapy because of the potential for developing hypokalemia. (Metazolamid etiketi, İlaç etkileşimleri)

  • MetforminbiguanidOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • MetildopaantihipertansifOrta

    If not, corticosteroids may be given and other causes of anemia should be considered. (Metildopa etiketi, Uyarılar)

  • MetiltestosteronandrojenOrta

    Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • This can be corrected by giving appropriate doses of corticosteroids. (Metirapon etiketi, Uyarılar ve önlemler)

  • MetoheksitalbarbitüratOrta

    Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Metolazontiyazid diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Midodrinalfa adrenerjik agonistOrta

    The potential for supine hypertension should be carefully monitored in these patients and may be minimized by either reducing the dose of fludrocortisone acetate or decreasing the salt intake prior to initiation of treatment with midodrine hydrochloride. (Midodrin etiketi, İlaç etkileşimleri)

  • MiglitolantidiyabetikOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • MoksifloksasinflorokinolonOrta

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Moksifloksasin etiketi, Uyarılar ve önlemler)

  • MometazonkortikosteroidOrta

    Although ASMANEX HFA may improve control of asthma symptoms during these episodes, in recommended doses it supplies less than normal physiological amounts of corticosteroid systemically and does NOT provide the mineralocorticoid activity necessary for coping with these emergencies. (Mometazon etiketi, Uyarılar ve önlemler)

  • Montelukastlökotrien reseptör antagonistiOrta

    Inhaled corticosteroid may be reduced gradually. (Montelukast etiketi, Uyarılar ve önlemler)

  • MorfinopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Morfin etiketi, Uyarılar ve önlemler)

  • NabumetonNSAİİOrta

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (Nabumeton etiketi, Uyarılar)

  • NalbufinopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Nalbufin etiketi, Uyarılar)

  • Naltrekson ve bupropionopioid antagonistiOrta

    …hypoglycemia concomitant administration of medications that may lower the seizure threshold, including other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, systemic steroids Recommendations for Reducing the Risk of Seizure: Clinical experience with bupropion suggests that the risk of seizure may be minimized by adhering to the recommended… (Naltrekson ve bupropion etiketi, Uyarılar ve önlemler)

  • NaproksenNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Naproksen etiketi, Uyarılar ve önlemler)

  • Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Naproksen ve esomeprazol etiketi, Uyarılar ve önlemler)

  • NateglinidmeglitinidOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Use OFEV with caution when treating patients with recent abdominal surgery, previous history of diverticular disease or receiving concomitant corticosteroids or NSAIDs. (Nintedanib etiketi, Uyarılar ve önlemler)

  • Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Noretisteron ve etinilestradioloral kontraseptifOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Norgestimat ve etinilestradioloral kontraseptifOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Norgestrel ve etinilestradioloral kontraseptifOrta

    Estrogen —increased levels of corticosteroid-binding globulin thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • OfloksasinflorokinolonOrta

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in those taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Ofloksasin etiketi, Uyarılar)

  • OksaprozinNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Oksaprozin etiketi, Uyarılar ve önlemler)

  • OksikodonopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Oksikodon etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Oksikodon ve parasetamol etiketi, Uyarılar ve önlemler)

  • OksimorfonopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Oksimorfon etiketi, Uyarılar ve önlemler)

  • OliseridinopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Oliseridin etiketi, Uyarılar ve önlemler)

  • Olmesartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Olmesartan, amlodipin ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Corticosteroid Reduction: Do not abruptly discontinue corticosteroids upon initiation of OMLYCLO therapy. (Omalizumab etiketi, Uyarılar ve önlemler)

  • Aspirin — increased ulcerogenic effect; decreased pharmacologic effect of aspirin. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • PamidronatbifosfonatOrta

    Many of these patients were also receiving chemotherapy and corticosteroids, which may be risk factors for ONJ. (Pamidronat etiketi, Uyarılar ve önlemler)

  • Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy, concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Parasetamol ve ibuprofen etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Parasetamol ve kodein etiketi, Uyarılar)

  • If adrenal insufficiency is suspected, it should be confirmed and treated per standard of care with exogenous glucocorticoids at replacement doses . (Pasireotid etiketi, Uyarılar ve önlemler)

  • Treatment has consisted of high doses of corticosteroids alone or, in some cases, concomitantly with an immunosuppressant. (Penisilamin etiketi, Uyarılar)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Pentazosin ve nalokson etiketi, Uyarılar)

  • PetidinopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Petidin etiketi, Uyarılar ve önlemler)

  • PioglitazontiyazolidindionOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Pioglitazon ve glimepiridtiyazolidindionOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Pioglitazon ve metformintiyazolidindionOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • PiroksikamNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Piroksikam etiketi, Uyarılar ve önlemler)

  • PotasyumVitamin ve mineralOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Potasyum klorürpotasyum takviyesiOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Potasyum sitratpotasyum takviyesiOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • PrimidonantikonvülsanOrta

    Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Prometazin ve kodein etiketi, Uyarılar ve önlemler)

  • PropofolMSS depresanıOrta

    The following appear to be major risk factors for the development of these events: decreased oxygen delivery to tissues; serious neurological injury and/or sepsis; high dosages of one or more of the following pharmacological agents: vasoconstrictors, steroids, inotropes and/or prolonged, high-dose infusions of propofol (> 5 mg/kg/hour for > 48 hours). (Propofol etiketi, Uyarılar ve önlemler)

  • Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • RepaglinidmeglitinidOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • RifampisinantibiyotikOrta

    Barbiturates, phenytoin, or rifampin —increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • RifapentinantibiyotikOrta

    …Haloperidol Barbiturates Phenobarbital Benzodiazepines Diazepam Beta-Blockers Propranolol Calcium Channel Blockers Diltiazem, nifedipine, verapamil Cardiac Glycoside Preparations Digoxin Corticosteroids Prednisone Fibrates Clofibrate Oral Hypoglycemics Sulfonylureas (e.g., glyburide, glipizide) Hormonal Contraceptives/Progestins Ethinyl estradiol, levonorgestrel Immunosuppressants… (Rifapentin etiketi, İlaç etkileşimleri)

  • RisedronatbifosfonatOrta

    …the jaw include invasive dental procedures (for example, tooth extraction, dental implants, boney surgery), diagnosis of cancer, concomitant therapies (for example, chemotherapy, corticosteroids, angiogenesis inhibitors), poor oral hygiene, and co-morbid disorders (for example, periodontal and/or other pre-existing dental disease, anemia, coagulopathy, infection,… (Risedronat etiketi, Uyarılar ve önlemler)

  • RitonavirantiretroviralOrta

    Systemic/Inhaled/ Nasal/Ophthalmic Corticosteroids: e.g., betamethasone budesonide ciclesonide dexamethasone fluticasone methylprednisolone mometasone prednisone triamcinolone ↑ glucocorticoids Coadministration with corticosteroids whose exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing’s syndrome and adrenal suppression.Alternative… (Ritonavir etiketi, İlaç etkileşimleri)

  • RivaroksabanantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Rokuronyumnöromüsküler blokerOrta

    Therefore, for patients receiving both neuromuscular blocking agents (including Rocuronium Bromide Injection) and corticosteroids, the period of use of the neuromuscular blocking agent should be limited as much as possible and only used in the setting where in the opinion of the prescribing physician, the specific advantages of the drug outweigh the risk. (Rokuronyum etiketi, Uyarılar ve önlemler)

  • SaksagliptinDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Saksagliptin ve metforminDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Salbutamolbeta adrenerjik agonistOrta

    If the patient needs more doses of Albuterol Sulfate HFA than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (Salbutamol etiketi, Uyarılar ve önlemler)

  • SalsalatNSAİİOrta

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • SefoksitinsefalosporinOrta

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Sefoksitin etiketi, Uyarılar ve önlemler)

  • SelekoksibNSAİİOrta

    Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, antiplatelet drugs (such as aspirin), anticoagulants; or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Selekoksib etiketi, Uyarılar ve önlemler)

  • SemaglutidGLP-1 reseptör agonistiOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • SiklesonidkortikosteroidOrta

    Although ALVESCO may provide control of asthma symptoms during these episodes, in recommended doses it supplies less than normal physiological amounts of corticosteroid systemically and does NOT provide the mineralocorticoid activity that is necessary for coping with these emergencies. (Siklesonid etiketi, Uyarılar ve önlemler)

  • SiprofloksasinflorokinolonOrta

    The risk of developing fluoroquinolone-associated tendinitis and tendon rupture is increased in patients over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants. (Siprofloksasin etiketi, Uyarılar ve önlemler)

  • SitagliptinDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Sitagliptin ve metforminDPP-4 inhibitörüOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • SitarabinantimetabolitOrta

    These reactions include reversible corneal toxicity, and hemorrhagic conjunctivitis, which may be prevented or diminished by prophylaxis with a local corticosteroid eye drop; cerebral and cerebellar dysfunction, including personality changes, somnolence and coma, usually reversible; severe gastrointestinal ulceration, including pneumatosis cystoides intestinalis… (Sitarabin etiketi, Uyarılar)

  • Use of corticosteroids may cause a protein catabolic state and, thereby, potentially increase plasma ammonia levels in patients with impaired ability to form urea. (Sodyum fenilasetat ve sodyum benzoat etiketi, İlaç etkileşimleri)

  • Valproic Acid, Haloperidol, or Corticosteroids : May increase plasma ammonia level; monitor ammonia levels closely. (Sodyum fenilbütirat etiketi, İlaç etkileşimleri)

  • Sodyum polistiren sülfonatpotasyum takviyesiOrta

    Monitor serum potassium levels; use potassium supplements if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Spironolaktonaldosteron antagonistiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Spironolakton ve hidroklorotiyazidaldosteron antagonistiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • SulindakNSAİİOrta

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (Sulindak etiketi, Uyarılar)

  • Other factors that increase the risk for gastrointestinal bleeding in patients treated with NSAIDs include longer duration of NSAID therapy; concomitant use of oral corticosteroids, aspirin, anticoagulants, or selective serotonin reuptake inhibitors (SSRIs); smoking; use of alcohol; older age; and poor general health status. (Sumatriptan ve naproksen etiketi, Uyarılar ve önlemler)

  • Süksinilkolinnöromüsküler blokerOrta

    The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions (5.9) ]. (Süksinilkolin etiketi, İlaç etkileşimleri)

  • SülfasalazinsülfonamidOrta

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • TapentadolopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Tapentadol etiketi, Uyarılar ve önlemler)

  • Telmisartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Pneumocystis Pneumonia (PCP) : Closely monitor all patients, particularly those receiving steroids, for the development of lymphopenia and PCP. (Temozolomid etiketi, Uyarılar ve önlemler)

  • If ILD is suspected, discontinue TORISEL, and consider use of corticosteroids and/or antibiotics. (Temsirolimus etiketi, Uyarılar ve önlemler)

  • TeofilinmetilksantinOrta

    Dosage Increases: Increases in the dose of theophylline should not be made in response to an acute exacerbation of symptoms of chronic lung disease since theophylline provides little added benefit to inhaled beta2 -selective agonists and systemically administered corticosteroids in this circumstance and increases the risk of adverse effects. (Teofilin etiketi, Uyarılar)

  • Terbutalinbeta adrenerjik agonistOrta

    If the patient needs more doses of terbutaline sulfate tablets than usual, this may be a marker of destabilization of asthma and requires reevaluation of the patient and the treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, e.g., corticosteroids. (Terbutalin etiketi, Uyarılar)

  • Teriparatidtiroid hormonuOrta

    Risk factors for development of calciphylaxis include underlying auto-immune disease, kidney failure, and concomitant warfarin or systemic corticosteroid use. (Teriparatid etiketi, Uyarılar ve önlemler)

  • Glucocorticoids : Patients receiving glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in maintenance or stress doses following initiation of EGRIFTA SV. (Tesamorelin etiketi, İlaç etkileşimleri)

  • TestosteronandrojenOrta

    Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)—enhanced tendency toward edema. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • TiotropiumantikolinerjikOrta

    Concomitant Respiratory Medications SPIRIVA RESPIMAT has been used concomitantly with short-acting and long-acting sympathomimetic (beta-agonists) bronchodilators, methylxanthines, oral and inhaled steroids, antihistamines, mucolytics, leukotriene modifiers, cromones, and anti-IgE treatment without increases in adverse reactions. (Tiotropium etiketi, İlaç etkileşimleri)

  • TirzepatidGLP-1 reseptör agonistiOrta

    Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • TolmetinNSAİİOrta

    Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. (Tolmetin etiketi, Uyarılar)

  • Torasemidkıvrım (loop) diüretiğiOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • TramadolopioidOrta

    If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Tramadol etiketi, Uyarılar ve önlemler)

  • If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids. (Tramadol ve parasetamol etiketi, Uyarılar ve önlemler)

  • Interrupt TRAZIMERA infusion in all patients experiencing dyspnea, clinically significant hypotension, and intervention of medical therapy administered (which may include epinephrine, corticosteroids, diphenhydramine, bronchodilators, and oxygen). (Trastuzumab etiketi, Uyarılar ve önlemler)

  • Triamterenpotasyum tutucu diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Triamteren ve hidroklorotiyazidpotasyum tutucu diüretikOrta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Valproik asitantikonvülsanOrta

    Oral Contraceptive Steroids Administration of a single-dose of ethinyloestradiol (50 mcg)/levonorgestrel (250 mcg) to 6 women on valproate (200 mg BID) therapy for 2 months did not reveal any pharmacokinetic interaction. (Valproik asit etiketi, İlaç etkileşimleri)

  • Valsartan ve hidroklorotiyazidanjiyotensin II reseptör blokeri (ARB)Orta

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • VarfarinantikoagülanOrta

    Oral anticoagulants — decreased prothrombin time response. (Fludrokortizon etiketi, İlaç etkileşimleri)

  • Vorikonazolazol antifungalOrta

    • Adrenal Dysfunction : Carefully monitor patients receiving voriconazole and corticosteroids (via all routes of administration) for adrenal dysfunction both during and after voriconazole treatment. (Vorikonazol etiketi, Uyarılar ve önlemler)

  • Prior to the first BIZENGRI infusion, premedicate with a corticosteroid, an H1 antihistamine and acetaminophen to reduce the risk of IRRs [see Dosage and Administration (2.4) ]. (Zenokutuzumab etiketi, Uyarılar ve önlemler)

  • Zoledronik asitbifosfonatOrta

    A dental examination with appropriate preventive dentistry should be considered prior to treatment with bisphosphonates in patients with a history of concomitant risk factors (e.g., cancer, chemotherapy, angiogenesis inhibitors, radiotherapy, corticosteroids, poor oral hygiene, preexisting dental disease or infection, anemia, coagulopathy). (Zoledronik asit etiketi, Uyarılar ve önlemler)

Minör değinmeler (50)

  • AlteplazMinör

    If signs of hypersensitivity occur, e.g. anaphylactoid reaction or angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy (e.g., antihistamines, intravenous corticosteroids, epinephrine). (Alteplaz etiketi, Uyarılar ve önlemler)

  • AmfetaminMSS uyarıcısıMinör

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Amfetamin etiketi, İlaç etkileşimleri)

  • Amfetamin ve dekstroamfetaminMSS uyarıcısıMinör

    Interference with Laboratory Tests Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Amfetamin ve dekstroamfetamin etiketi, İlaç etkileşimleri)

  • AmikasinaminoglikozidMinör

    Most patients with hypersensitivity pneumonitis discontinued treatment with ARIKAYCE and received treatment with corticosteroids [see Adverse Reactions (6.1) ] . (Amikasin etiketi, Uyarılar ve önlemler)

  • AmiodaronantiaritmikMinör

    Antithyroid drugs, β-adrenergic blockers, temporary corticosteroid therapy may be necessary to treat the symptoms of hyperthyroidism. (Amiodaron etiketi, Uyarılar ve önlemler)

  • Ampisilinpenisilin antibiyotikMinör

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (Ampisilin etiketi, Uyarılar)

  • Bempedoik asitOATP1B1 inhibitörüMinör

    Tendon rupture may occur more frequently in patients over 60 years of age, in those taking corticosteroid or fluoroquinolone drugs, in patients with renal failure, and in patients with previous tendon disorders. (Bempedoik asit etiketi, Uyarılar ve önlemler)

  • Discontinue in patients who develop a severe infusion-related reaction and administer appropriate medical therapy (e.g., epinephrine, corticosteroids, intravenous antihistamines, bronchodilators and/or oxygen). (Bevasizumab etiketi, Uyarılar ve önlemler)

  • BusulfanMinör

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (Busulfan etiketi, Uyarılar)

  • D vitaminiVitamin ve mineralMinör

    Prednizon gibi kortikosteroidler kalsiyum emilimini azaltır ve D vitamini metabolizmasını bozarak kemik kaybına katkıda bulunur. (NIH Office of Dietary Supplements, Vitamin D)

  • DasatinibMinör

    Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (Dasatinib etiketi, Uyarılar ve önlemler)

  • DekstroamfetaminMSS uyarıcısıMinör

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Dekstroamfetamin etiketi, İlaç etkileşimleri)

  • Droperidoldopamin antagonistiMinör

    These would include diuretics, laxatives and supraphysiological use of steroid hormones with mineralocorticoid potential. (Droperidol etiketi, İlaç etkileşimleri)

  • EfavirenzantiretroviralMinör

    Appropriate antihistamines and/or corticosteroids may improve the tolerability and hasten the resolution of rash. (Efavirenz etiketi, Uyarılar ve önlemler)

  • Appropriate antihistamines and/or corticosteroids may improve the tolerability and hasten the resolution of rash. (Efavirenz, lamivudin ve tenofovir etiketi, Uyarılar ve önlemler)

  • FludarabinantimetabolitMinör

    Steroids may or may not be effective in controlling these hemolytic episodes. (Fludarabin etiketi, Uyarılar ve önlemler)

  • FluoksetinSSRIMinör

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (Fluoksetin etiketi, Uyarılar ve önlemler)

  • GlukagonMinör

    In the reported cases NME resolved with discontinuation of the glucagon, and treatment with corticosteroids was not effective. (Glukagon etiketi, Uyarılar ve önlemler)

  • İpratropiumantikolinerjikMinör

    ATROVENT HFA has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines, oral and inhaled steroids commonly used in the treatment of COPD. (İpratropium etiketi, İlaç etkileşimleri)

  • KalsitriolD vitamini analoğuMinör

    Corticosteroids A relationship of functional antagonism exists between vitamin D analogues, which promote calcium absorption, and corticosteroids, which inhibit calcium absorption. (Kalsitriol etiketi, İlaç etkileşimleri)

  • Kannabidiol (reçeteli)antikonvülsanMinör

    Some subjects in the EPIDIOLEX clinical trials had pruritus, erythema, and angioedema requiring treatment, including corticosteroids and antihistamines. (Kannabidiol (reçeteli) etiketi, Uyarılar ve önlemler)

  • KarbamazepinantikonvülsanMinör

    …clozapine, cyclosporin, delavirdine, desipramine, diazepam, dicumarol, dihydropyridine calcium channel blockers (e.g., felodipine), doxycycline, ethosuximide, everolimus, felbamate, glucocorticoids, haloperidol, imatinib, itraconazole, lamotrigine, levothyroxine, lorazepam, methadone, methsuxamide, mianserin, midazolam, mirtazapine, nefazodone, olanzapine, oral… (Karbamazepin etiketi, İlaç etkileşimleri)

  • KininantimalaryalMinör

    Drug/Laboratory Interactions Quinine may produce an elevated value for urinary 17-ketogenic steroids when the Zimmerman method is used. (Kinin etiketi, İlaç etkileşimleri)

  • KlofarabinantimetabolitMinör

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Klofarabin etiketi, Uyarılar ve önlemler)

  • Klomifenselektif östrojen reseptör modülatörüMinör

    Elevated urinary steroid levels, varying degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. (Klomifen etiketi, Uyarılar)

  • The recovery of the adrenal gland may take from days to months so patients should be protected from the stress (e.g., trauma or surgery) by the use of corticosteroids during the period of stress. (Kortikotropin etiketi, Uyarılar ve önlemler)

  • Patients with Grade 1 and 2 TFR may also be treated with corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs) and/or narcotic analgesics for management of TFR symptoms. (Lenalidomid etiketi, Uyarılar ve önlemler)

  • MelfalanMinör

    The infusion should be terminated immediately, followed by the administration of volume expanders, pressor agents, corticosteroids, or antihistamines at the discretion of the physician. (Melfalan etiketi, Uyarılar)

  • MetamfetaminMSS uyarıcısıMinör

    Drug/Laboratory Test Interactions Amphetamines can cause a significant elevation in plasma corticosteroid levels. (Metamfetamin etiketi, İlaç etkileşimleri)

  • Metimazolantitiroid ilaçMinör

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (Metimazol etiketi, Uyarılar)

  • Following concurrent administration of mitoxantrone injection with corticosteroids, no evidence of drug interactions has been observed. (Mitoksantron etiketi, İlaç etkileşimleri)

  • Naltreksonopioid antagonistiMinör

    Both cases required hospitalization, and resolved after treatment with antibiotics and corticosteroids. (Naltrekson etiketi, Uyarılar ve önlemler)

  • Oksasilinpenisilin antibiyotikMinör

    If an allergic reaction occurs, the drug should be discontinued and the patient should receive supportive treatment, e.g. , artificial maintenance of ventilation, pressor amines, antihistamines, and corticosteroids. (Oksasilin etiketi, Uyarılar)

  • Olanzapin ve fluoksetinantipsikotikMinör

    Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these reactions were reported to recover completely. (Olanzapin ve fluoksetin etiketi, Uyarılar ve önlemler)

  • Penisilin Gpenisilin antibiyotikMinör

    Oxygen, intravenous steroids, and airway management, including intubation, should also be administered as indicated. (Penisilin G etiketi, Uyarılar)

  • Penisilin Vpenisilin antibiyotikMinör

    OXYGEN, INTRAVENOUS STEROIDS, AND AIRWAY MANAGEMENT, INCLUDING INTUBATION, SHOULD ALSO BE ADMINISTERED AS INDICATED. (Penisilin V etiketi, Uyarılar)

  • PrednizolonkortikosteroidMinör

    Since mineralocorticoid secretion may be impaired, salt and/or a mineralocorticoid should be administered concurrently. (Prednizolon etiketi, Uyarılar ve önlemler)

  • PrednizonkortikosteroidMinör

    Since mineralocorticoid secretion may be impaired, salt and/or a mineralocorticoid should be administered concurrently. (Prednizon etiketi, Uyarılar ve önlemler)

  • Propiltiourasilantitiroid ilaçMinör

    In some cases, vasculitis resolved/improved with drug discontinuation; however, more severe cases required treatment with additional measures including corticosteroids, immunosuppressant therapy, and plasmapheresis. (Propiltiourasil etiketi, Uyarılar)

  • Raloksifenselektif östrojen reseptör modülatörüMinör

    Other Concomitant Medications EVISTA can be concomitantly administered with ampicillin, amoxicillin, antacids, corticosteroids, and digoxin [see Clinical Pharmacology ( 12.3 )] . (Raloksifen etiketi, İlaç etkileşimleri)

  • SefadroksilsefalosporinMinör

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Sefadroksil etiketi, Uyarılar ve önlemler)

  • SefaklorsefalosporinMinör

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Sefaklor etiketi, Uyarılar)

  • SefdinirsefalosporinMinör

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Sefdinir etiketi, Uyarılar)

  • SefotetansefalosporinMinör

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Sefotetan etiketi, Uyarılar)

  • SefprozilsefalosporinMinör

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, INTRAVENOUS FLUIDS, INTRAVENOUS ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Sefprozil etiketi, Uyarılar)

  • SeftazidimsefalosporinMinör

    SERIOUS ACUTE HYPERSENSITIVITY REACTIONS MAY REQUIRE TREATMENT WITH EPINEPHRINE AND OTHER EMERGENCY MEASURES, INCLUDING OXYGEN, IV FLUIDS, IV ANTIHISTAMINES, CORTICOSTEROIDS, PRESSOR AMINES, AND AIRWAY MANAGEMENT, AS CLINICALLY INDICATED. (Seftazidim etiketi, Uyarılar)

  • SeftriaksonsefalosporinMinör

    Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures including oxygen, corticosteroids, intravenous fluids, intravenous antihistamines, pressor amines, and airway management, as clinically indicated. (Seftriakson etiketi, Uyarılar ve önlemler)

  • If symptoms of hypersensitivity occur, initiate appropriate therapy (e.g., antihistamines, corticosteroids, epinephrine). (Tenekteplaz etiketi, Uyarılar ve önlemler)

  • TobramisinaminoglikozidMinör

    In clinical studies, patients receiving TOBI Podhaler continued to take dornase alfa, bronchodilators, inhaled corticosteroids, and macrolides. (Tobramisin etiketi, İlaç etkileşimleri)

  • ZiprasidonantipsikotikMinör

    Most patients improved promptly with adjunctive treatment with antihistamines or steroids and/or upon discontinuation of ziprasidone, and all patients experiencing these reactions were reported to recover completely. (Ziprasidon etiketi, Uyarılar ve önlemler)

Kullandığınız her şeyi Fludrokortizon ile karşılaştırın. Tüm listenizi ekleyin; her çift tek seferde kontrol edilir.

Sorgulama aracında aç

Tıbbi tavsiye değildir. Şiddet derecesi sizin koşullarınızı değil, etiketin ifadesini yansıtır. “Majör” işareti gözetim altında olağan bir uygulama olabilir, “minör” işareti ise yüksek dozlarda önem kazanabilir. Bir eczacıya danışın.