تداخلات سلفاسالازين

CONTRAINDICATIONS Atenolol and chlorthalidone is contraindicated in patients with: sinus bradycardia; heart block greater than first degree; cardiogenic shock; overt cardiac failure (See WARNINGS ); anuria; hypersensitivity to this product or to sulfonamide-derived drugs. (نشرة أتينولول وكلورثاليدون، موانع الاستعمال)

Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (نشرة إربيسارتان وهيدروكلوروثيازيد، موانع الاستعمال)

Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (نشرة إنالابريل وهيدروكلوروثيازيد، موانع الاستعمال)

Known hypersensitivity to indapamide or to other sulfonamide-derived drugs. (نشرة إنداباميد، موانع الاستعمال)

Intervention: The concomitant use of indomethacin with other NSAIDs or salicylates, especially diflunisal, is not recommended. (نشرة إندوميثاسين، التداخلات الدوائية)

Intervention: The concomitant use of oxaprozin with other NSAIDs or salicylates is not recommended. (نشرة أوكسابروزين، التداخلات الدوائية)

Because of the hydrochlorothiazide component, olmesartan medoxomil, amlodipine and hydrochlorothiazide tablet is contraindicated in patients with anuria, hypersensitivity to any component, or hypersensitivity to other sulfonamide-derived drugs. (نشرة أولميسارتان وأملوديبين وهيدروكلوروثيازيد، موانع الاستعمال)

Intervention: The concomitant use of ibuprofen with other NSAIDs or salicylates is not recommended. (نشرة إيبوبروفين، التداخلات الدوائية)

Intervention: The concomitant use of ibuprofen and famotidine tablet with other NSAIDs or salicylates is not recommended. (نشرة إيبوبروفين وفاموتيدين، التداخلات الدوائية)

Intervention: The concomitant use of ibuprofen with other NSAIDs or salicylates is not recommended. (نشرة باراسيتامول وإيبوبروفين، التداخلات الدوائية)

In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (نشرة بروبينيسيد، التحذيرات)

In patients on probenecid and colchicine the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (نشرة بروبينيسيد وكولشيسين، التحذيرات)

Intervention: The concomitant use of piroxicam with other NSAIDs or salicylates is not recommended. (نشرة بيروكسيكام، التداخلات الدوائية)

CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (نشرة بيسوبرولول وهيدروكلوروثيازيد، موانع الاستعمال)

Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (نشرة بينازيبريل وهيدروكلوروثيازيد، موانع الاستعمال)

Use in patients with known history of an allergic reaction to sulfonamide derivatives. (نشرة بيوغليتازون وغليميبيريد، موانع الاستعمال)

If a patient reports a serious or life-threatening sulfa allergy, caution is warranted when administering tamsulosin hydrochloride capsules. (نشرة تامسولوسين، التحذيرات والاحتياطات)

Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (نشرة تريامتيرين وهيدروكلوروثيازيد، موانع الاستعمال)

Intervention: The concomitant use of mefenamic acid with other NSAIDs or salicylates is not recommended. (نشرة حمض الميفيناميك، التداخلات الدوائية)

If a patient reports a serious or life-threatening sulfa allergy, caution is warranted when administering tamsulosin-containing products, including JALYN. (نشرة دوتاستيريد وتامسولوسين، التحذيرات والاحتياطات)

KEVEYIS is contraindicated in the following circumstances: Hypersensitivity to dichlorphenamide or other sulfonamides [see Warnings and Precautions (5.1) ] Concomitant use of KEVEYIS and high dose aspirin [see Warnings and Precautions (5.2) and Drug Interactions (7.1) ] Severe pulmonary disease, limiting compensation to metabolic acidosis caused by KEVEYIS [see… (نشرة ديكلورفيناميد، موانع الاستعمال)

Intervention: The concomitant use of diclofenac with other NSAIDs or salicylates is not recommended. (نشرة ديكلوفيناك، التداخلات الدوائية)

Intervention: The concomitant use of diclofenac sodium/misoprostol with other NSAIDs or salicylates is not recommended. (نشرة ديكلوفيناك وميزوبروستول، التداخلات الدوائية)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (نشرة سبيرونولاكتون وهيدروكلوروثيازيد، موانع الاستعمال)

Coadministration of VOSEVI with BCRP substrates (e.g., methotrexate, mitoxantrone, imatinib, irinotecan, lapatinib, rosuvastatin, sulfasalazine, topotecan) is not recommended [see Clinical Pharmacology (12.3) ]. (نشرة سوفوسبوفير وفيلباتاسفير، التداخلات الدوائية)

Intervention: The concomitant use of naproxen with other NSAIDs or salicylates is not recommended. (نشرة سوماتريبتان ونابروكسين، التداخلات الدوائية)

Sepiapterin Reductase (SR) Inhibitors : Avoid concomitant use (e.g. sulfasalazine or sulfamethoxazole). (نشرة سيبيابترين، التداخلات الدوائية)

Cidofovir injection is contraindicated in patients with a history of clinically severe hypersensitivity to probenecid or other sulfa-containing medications. (نشرة سيدوفوفير، موانع الاستعمال)

• In patients who have demonstrated allergic-type reactions to sulfonamides [ see Warnings and Precautions (5.7) ]. (نشرة سيليكوكسيب، موانع الاستعمال)

• Hypersensitivity to sulfonamide derivatives. ▪ Known hypersensitivity to glipizide or any of the product's ingredients ( 4 ). ▪ Hypersensitivity to sulfonamide derivatives ( 4 ). (نشرة غليبيزيد، موانع الاستعمال)

• Sulfonamide derivatives: Patients who have developed an allergic reaction to sulfonamide derivatives may develop an allergic reaction to glimepiride tablets.Do not use glimepiride tablets in patients who have a history of an allergic reaction to sulfonamide derivatives. (نشرة غليميبيريد، موانع الاستعمال)

Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (نشرة فالسارتان وهيدروكلوروثيازيد، موانع الاستعمال)

Intervention: The concomitant use of flurbiprofen with other NSAIDs or salicylates is not recommended. (نشرة فلوربيبروفين، التداخلات الدوائية)

Fosinopril sodium and hydrochlorothiazide is also contraindicated in patients who are hypersensitive to fosinopril, to any other ACE inhibitor, to hydrochlorothiazide, or other sulfonamide-derived drugs, or any other ingredient or component in the formulation. (نشرة فوسينوبريل وهيدروكلوروثيازيد، موانع الاستعمال)

Contraindications: ANTICHOLIUM ® should not be used in the presence of hypersensitivity to physostigmine salicylate, bronchial asthma, ulcers associated with tissue destruction (gangrene), coronary heart disease, constipation (mechanical obstipation), mechanical ischuria (urinary retention), hereditary form of muscle atrophy (myotonic dystrophy), closed traumatic… (نشرة فيزوستيغمين، موانع الاستعمال)

Intervention: The concomitant use of fenoprofen with other NSAIDs or salicylates is not recommended. (نشرة فينوبروفين، التداخلات الدوائية)

CONTRAINDICATIONS Candesartan cilexetil and hydrochlorothiazide tablets are contraindicated in patients who are hypersensitive to candesartan, to hydrochlorothiazide or to other sulfonamide-derived drugs. (نشرة كانديسارتان وهيدروكلوروثيازيد، موانع الاستعمال)

THALITONE is contraindicated in patients with anuria or hypersensitivity to chlorthalidone or other sulfonamide-derived drugs. (نشرة كلورثاليدون، موانع الاستعمال)

Therefore, chloroprocaine should not be used in any condition in which a sulfonamide drug is being employed. (نشرة كلوروبروكايين، الاحتياطات)

Hypersensitivity to this product or to other sulfonamide-derived drugs. (نشرة كلوروثيازيد، موانع الاستعمال)

Because of the hydrochlorothiazide components, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (نشرة كينابريل وهيدروكلوروثيازيد، موانع الاستعمال)

Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (نشرة ليزينوبريل وهيدروكلوروثيازيد، موانع الاستعمال)

Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (نشرة ميتوبرولول وهيدروكلوروثيازيد، موانع الاستعمال)

Patients receiving antibiotics and sulfonamides should generally not be treated with ganglion blockers. (نشرة ميكاميلامين، موانع الاستعمال)

Intervention: The concomitant use of meloxicam with other NSAIDs or salicylates is not recommended. (نشرة ميلوكسيكام، التداخلات الدوائية)

Intervention: The concomitant use of naproxen with other NSAIDs or salicylates is not recommended. (نشرة نابروكسين، التداخلات الدوائية)

Intervention: The concomitant use of naproxen and esomeprazole magnesium delayed-release tablets with other NSAIDs or salicylates is not recommended. (نشرة نابروكسين وإيزوميبرازول، التداخلات الدوائية)

In patients with hypersensitivity to sulfonamide-derived drugs. (نشرة هيدروكلوروثيازيد، موانع الاستعمال)

The concomitant use of ibuprofen with other NSAIDs or salicylates is not recommended. (نشرة هيدروكودون وإيبوبروفين، التداخلات الدوائية)

Particular caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid in combination with Adapalene Cream, 0.1%. (نشرة أدابالين، التداخلات الدوائية)

…nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine Monoamine Oxidase Inhibitors, Nonselective Beta-Adrenergic Antagonists, or Tricyclic Antidepressants: May produce severe, prolonged hypertension ( 7 ) (نشرة أرتيكايين وأدرينالين، التداخلات الدوائية)

…(e.g., atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin, repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin, sulfasalazine, topotecan). (نشرة إلترومبوباغ، التداخلات الدوائية)

Use with caution in patients with a known hypersensitivity to sulfonamides ( 5.8 ) (نشرة ألموتريبتان، التحذيرات والاحتياطات)

Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics. (نشرة إنسولين أسبارت، التداخلات الدوائية)

…May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, SGLT-2 inhibitors. (نشرة إنسولين ديتيمير، التداخلات الدوائية)

…May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, SGLT-2 inhibitors. (نشرة إنسولين ديغلوديك، التداخلات الدوائية)

…Receptor Blocking Agents, Disopyramide, Fibrates, Fluoxetine, Monoamine Oxidase Inhibitors, Pentoxifylline, Pramlintide, Salicylates, Somatostatin Analogs (e.g., octreotide), and Sulfonamide Antibiotics Prevention or Management Monitor blood glucose more frequently and modify AFREZZA dosage, as clinically indicated, when used concomitantly with these drugs. (نشرة إنسولين عادي (بشري)، التداخلات الدوائية)

…May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors. (نشرة إنسولين غلارجين، التداخلات الدوائية)

Clinically Significant Drug Interactions with LYUMJEV Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (نشرة إنسولين ليسبرو، التداخلات الدوائية)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (نشرة أولميسارتان وهيدروكلوروثيازيد، التحذيرات والاحتياطات)

Sulfasalazine Patients in a clinical study who were on established therapy with sulfasalazine, to which Enbrel was added, were noted to develop a mild decrease in mean neutrophil counts in comparison to groups treated with either Enbrel or sulfasalazine alone. (نشرة إيتانرسبت، التداخلات الدوائية)

CHCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid and temazepam. (نشرة إيتونوجيستريل وإيثينيل إستراديول، التداخلات الدوائية)

Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects. (نشرة بروموكريبتين، التداخلات الدوائية)

NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (نشرة بريدنيزولون، التداخلات الدوائية)

NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (نشرة بريدنيزون، التداخلات الدوائية)

…para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants… (نشرة بريلوكايين وأدرينالين، التداخلات الدوائية)

• Rare instances of acid-base alterations have occurred with high-dose salicylate therapy. (نشرة برينزولاميد، التداخلات الدوائية)

…para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent Inhalation Anesthetics Serious dose-related cardiac arrhythmias may occur if preparations containing a vasoconstrictor such as epinephrine (e.g., MARCAINE WITH… (نشرة بوبيفاكايين وأدرينالين، التداخلات الدوائية)

However, the concomitant use of other antifolic drugs or agents associated with myelosuppression including sulfonamides or trimethoprim- sulfamethoxazole combinations, proguanil, zidovudine, or cytostatic agents (e.g., methotrexate), while the patient is receiving pyrimethamine, may increase the risk of bone marrow suppression. (نشرة بيريميثامين، التداخلات الدوائية)

The clearance of salicylates may be increased with concurrent use of corticosteroids. (نشرة تريامسينولون، التداخلات الدوائية)

Nonsteroidal Anti-Inflammatory Drugs Because torsemide and salicylates compete for secretion by renal tubules, patients receiving high doses of salicylates may experience salicylate toxicity when torsemide is concomitantly administered. (نشرة توراسيميد، التداخلات الدوائية)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (نشرة تيلميسارتان وهيدروكلوروثيازيد، التحذيرات والاحتياطات)

Drug Interactions: Reduced absorption of folic acid and digoxin have been reported when those agents were administered concomitantly with sulfasalazine. (نشرة سلفاسالازين، التداخلات الدوائية)

Use with caution in patients with a known sulfonamide allergy. (نشرة دارونافير، التحذيرات والاحتياطات)

Monitor in patients with a known sulfonamide allergy. (نشرة دارونافير وكوبيسيستات، التحذيرات والاحتياطات)

High-Dose Salicylate Therapy Although acid-base and electrolyte disturbances were not reported in the clinical trials with dorzolamide hydrochloride ophthalmic solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associated with high-dose salicylate therapy). (نشرة دورزولاميد، التداخلات الدوائية)

High-Dose Salicylate Therapy Although acid-base and electrolyte disturbances were not reported in the clinical trials with dorzolamide hydrochloride ophthalmic solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associated with high-dose salicylate therapy). (نشرة دورزولاميد وتيمولول، التداخلات الدوائية)

Drug Interactions: Reduced absorption of folic acid and digoxin have been reported when those agents were administered concomitantly with sulfasalazine. (نشرة سلفاسالازين، التداخلات الدوائية)

COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (نشرة ديسوجيستريل وإيثينيل إستراديول، التداخلات الدوائية)

The clearance of salicylates may be increased with concurrent use of corticosteroids. (نشرة ديكساميثازون، التداخلات الدوائية)

…para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine NAROPIN should be used with caution in patients receiving other local anesthetics or agents structurally related to amide- type local anesthetics, since the toxic effects… (نشرة روبيفاكايين، التداخلات الدوائية)

ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (نشرة سالسالات، التداخلات الدوائية)

Conversely, agents such as indomethacin, probenecid and salicylates may displace sulfonamides from plasma albumin and increase the concentrations of free drug in plasma. (نشرة سلفاديازين، التداخلات الدوائية)

Like other sulfonamide-containing drugs, sulfamethoxazole and trimethoprim potentiates the effect of oral hypoglycemics. (نشرة سلفاميثوكسازول وتريميثوبريم، التداخلات الدوائية)

NSAIDs Use with caution Non-steroidal anti-inflammatory drugs (but not acetyl salicylic acid) in combination of very high doses of quinolones have been shown to provoke convulsions in pre-clinical studies and in postmarketing. (نشرة سيبروفلوكساسين، التداخلات الدوائية)

Serum salicylate concentrations may be decreased when griseofulvin is given concomitantly with salicylates. (نشرة غريزيوفولفين، التداخلات الدوائية)

…Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents. (نشرة غليبنكلاميد، التداخلات الدوائية)

Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (نشرة غليبيزيد وميتفورمين، الاحتياطات)

Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (نشرة فلودروكورتيزون، التداخلات الدوائية)

Coadministration of aspirin 150 mg/day with multiple daily doses of TRINTELLIX had no significant inhibitory effect on platelet aggregation or pharmacokinetics of aspirin and salicylic acid [see Clinical Pharmacology (12.3) ] . (نشرة فورتيوكسيتين، التداخلات الدوائية)

• Salicylates : Risk of salicylate toxicity ( 7.1 ) (نشرة فوروسيميد، التداخلات الدوائية)

Fosamprenavir calcium should be used with caution in patients with a known sulfonamide allergy. (نشرة فوسامبرينافير، التحذيرات والاحتياطات)

…voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine, sulfamethoxazole-trimethoprim Other Acute alcohol intake, amiodarone, chloramphenicol, chlordiazepoxide, disulfiram, estrogen,… (نشرة فوسفينيتوين، التداخلات الدوائية)

…voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine, sulfamethoxazole-trimethoprim Other Acute alcohol intake, amiodarone, chloramphenicol, chlordiazepoxide, disulfiram, estrogen,… (نشرة فينيتوين، التداخلات الدوائية)

Hyperventilation and Metabolic Acidosis: Sodium Phenylacetate and Sodium Benzoate Injection may cause side effects typically associated with salicylate overdose, such as hyperventilation and metabolic acidosis. (نشرة فينيل أسيتات الصوديوم وبنزوات الصوديوم، التحذيرات والاحتياطات)

Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (نشرة كيتورولاك، التداخلات الدوائية)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (نشرة لوسارتان وهيدروكلوروثيازيد، التحذيرات والاحتياطات)

…para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent Inhalation Anesthetics Serious dose-related cardiac arrhythmias may occur if preparations containing epinephrine are used in patients during or following the… (نشرة ليدوكايين وأدرينالين، التداخلات الدوائية)

…prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, isofamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sufonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (نشرة ليدوكايين وبريلوكايين، التداخلات الدوائية)

An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (نشرة ليفوثيروكسين، التداخلات الدوائية)

Other Drugs Clinical effect Concomitant use of CHCs may decrease systemic exposure of acetaminophen, morphine, salicylic acid, and temazepam. (نشرة ليفونورجيستريل وإيثينيل إستراديول، التداخلات الدوائية)

An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (نشرة ليوثيرونين، التداخلات الدوائية)

…procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (نشرة ميبيفاكايين، التداخلات الدوائية)

Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (نشرة ميتولازون، التداخلات الدوائية)

When daily doses of sulfasalazine 2 g and weekly doses of methotrexate 7.5 mg were coadministered to 15 rheumatoid arthritis patients in a drug-drug interaction study, the pharmacokinetic disposition of the drugs was not altered. (نشرة سلفاسالازين، التداخلات الدوائية)

The clearance of salicylates may be increased with concurrent use of corticosteroids. (نشرة ميثيل بريدنيزولون، التداخلات الدوائية)

Aminosalicylates Aminosalicylates (e.g., mesalamine, olsalazine or sulfasalazine) may inhibit the TPMT enzyme, which may increase the risk of myelosuppression when coadministered with mercaptopurine tablets. (نشرة ميركابتوبورين، التداخلات الدوائية)

…with Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan,… (نشرة ناتيغلينيد، التداخلات الدوائية)

COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (نشرة نورجيستريل وإيثينيل إستراديول، التداخلات الدوائية)

COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (نشرة نورجيستيمات وإيثينيل إستراديول، التداخلات الدوائية)

CHCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, and temazepam. (نشرة نوريلجيسترومين وإيثينيل إستراديول، التداخلات الدوائية)

In patients given very high doses (3,900 mg) of aspirin daily, increases in serum salicylate levels were seen when nizatidine, 150 mg b.i.d., was administered concurrently. (نشرة نيزاتيدين، التداخلات الدوائية)

• Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (نشرة هيالورونيداز، التداخلات الدوائية)

The clearance of salicylates may be increased with concurrent use of corticosteroids; this could lead to decreased salicylate serum levels or increase the risk of salicylate toxicity when corticosteroid is withdrawn. (نشرة هيدروكورتيزون، التداخلات الدوائية)

Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (نشرة أزرق الميثيلين، التحذيرات والاحتياطات)

Bacteriostatic Antibiotics : Chloramphenicol, erythromycins, sulfonamides, or tetracyclines may interfere with the bactericidal effect of penicillins. (نشرة أمبيسيلين، التداخلات الدوائية)

Other Antibacterials Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the bactericidal effects of penicillin. (نشرة أموكسيسيلين، التداخلات الدوائية)

In vitro studies have shown no binding displacement between entacapone and other highly bound drugs, such as warfarin, salicylic acid, phenylbutazone, and diazepam. (نشرة إنتاكابون، الاحتياطات)

These agents include medications such as: anticoagulants, platelet inhibitors including acetylsalicylic acid, salicylates, NSAIDs (including ketorolac tromethamine), dipyridamole, or sulfinpyrazone. (نشرة إينوكسابارين، التداخلات الدوائية)

Although the exact frequency of occurrence has not been determined, it has occurred in 3% of patients in controlled clinical trials of mesalamine or sulfasalazine. (نشرة بالسالازيد، التحذيرات والاحتياطات)

Drug Interactions Bacteriostatic antibacterials ( i.e. , chloramphenicol, erythromycins, sulfonamides or tetracyclines) may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (نشرة بنسلين G، التداخلات الدوائية)

Allergy to Sulfonamides Patients allergic to sulfonamides may show hypersensitivity to bumetanide. (نشرة بوميتانيد، التحذيرات)

Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (نشرة ريباغلينيد، التداخلات الدوائية)

Hepatotoxic Drugs Clinical trials in ALS patients excluded patients on concomitant medications which were potentially hepatotoxic (e.g., allopurinol, methyldopa, sulfasalazine). (نشرة ريلوزول، التداخلات الدوائية)

Drug-drug interaction studies in healthy subjects have been conducted with zileuton immediate-release tablets and digoxin, phenytoin, sulfasalazine, and naproxen. (نشرة زيلوتون، التداخلات الدوائية)

There is a potential cross-sensitivity between silver sulfadiazine and other sulfonamides. (نشرة سلفاديازين الفضة، التحذيرات والاحتياطات)

Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (نشرة غليبنكلاميد وميتفورمين، التداخلات الدوائية)

Although the exact frequency of occurrence has not been determined, it has occurred in 3% of patients in controlled clinical trials of mesalamine or sulfasalazine. (نشرة ميسالازين، التحذيرات والاحتياطات)