Interações de Sulfassalazina

Sulfassalazina (Azulfidine), sulfonamida, tem 128 interações documentadas nas bulas da FDA e nas fichas informativas que indexamos (graves: 49; moderadas: 65; leves: 14; casos em que uma bula relata não haver interação significativa: 0). Cada item abaixo cita a frase em que se baseia. Esta página de medicamento é um ponto de partida, não um veredito para a sua situação.

Interações segundo a bula

Interações graves (49)

  • Intervention: The concomitant use of mefenamic acid with other NSAIDs or salicylates is not recommended. (bula de Ácido mefenâmico, Interações medicamentosas)

  • Atenolol + clortalidonabetabloqueadorGrave

    CONTRAINDICATIONS Atenolol and chlorthalidone is contraindicated in patients with: sinus bradycardia; heart block greater than first degree; cardiogenic shock; overt cardiac failure (See WARNINGS ); anuria; hypersensitivity to this product or to sulfonamide-derived drugs. (bula de Atenolol + clortalidona, Contraindicações)

  • Benazepril + hidroclorotiazidainibidor da ECAGrave

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (bula de Benazepril + hidroclorotiazida, Contraindicações)

  • CONTRAINDICATIONS Bisoprolol fumarate and hydrochlorothiazide tablets are contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS ), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs. (bula de Bisoprolol + hidroclorotiazida, Contraindicações)

  • Candesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    CONTRAINDICATIONS Candesartan cilexetil and hydrochlorothiazide tablets are contraindicated in patients who are hypersensitive to candesartan, to hydrochlorothiazide or to other sulfonamide-derived drugs. (bula de Candesartana + hidroclorotiazida, Contraindicações)

  • CelecoxibeAINEGrave

    • In patients who have demonstrated allergic-type reactions to sulfonamides [ see Warnings and Precautions (5.7) ]. (bula de Celecoxibe, Contraindicações)

  • CidofovirantiviralGrave

    Cidofovir injection is contraindicated in patients with a history of clinically severe hypersensitivity to probenecid or other sulfa-containing medications. (bula de Cidofovir, Contraindicações)

  • Cloroprocaínaanestésico localGrave

    Therefore, chloroprocaine should not be used in any condition in which a sulfonamide drug is being employed. (bula de Cloroprocaína, Precauções)

  • Clorotiazidadiurético tiazídicoGrave

    Hypersensitivity to this product or to other sulfonamide-derived drugs. (bula de Clorotiazida, Contraindicações)

  • Clortalidonadiurético tiazídicoGrave

    THALITONE is contraindicated in patients with anuria or hypersensitivity to chlorthalidone or other sulfonamide-derived drugs. (bula de Clortalidona, Contraindicações)

  • DiclofenacoAINEGrave

    Intervention: The concomitant use of diclofenac with other NSAIDs or salicylates is not recommended. (bula de Diclofenaco, Interações medicamentosas)

  • Intervention: The concomitant use of diclofenac sodium/misoprostol with other NSAIDs or salicylates is not recommended. (bula de Diclofenaco + misoprostol, Interações medicamentosas)

  • Diclorfenamidainibidor da anidrase carbônicaGrave

    KEVEYIS is contraindicated in the following circumstances: Hypersensitivity to dichlorphenamide or other sulfonamides [see Warnings and Precautions (5.1) ] Concomitant use of KEVEYIS and high dose aspirin [see Warnings and Precautions (5.2) and Drug Interactions (7.1) ] Severe pulmonary disease, limiting compensation to metabolic acidosis caused by KEVEYIS [see… (bula de Diclorfenamida, Contraindicações)

  • Dutasterida + tansulosinainibidor da 5-alfa-redutaseGrave

    If a patient reports a serious or life-threatening sulfa allergy, caution is warranted when administering tamsulosin-containing products, including JALYN. (bula de Dutasterida + tansulosina, Advertências e precauções)

  • Enalapril + hidroclorotiazidainibidor da ECAGrave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Enalapril + hidroclorotiazida, Contraindicações)

  • Espironolactona + hidroclorotiazidaantagonista da aldosteronaGrave

    CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (bula de Espironolactona + hidroclorotiazida, Contraindicações)

  • FenoprofenoAINEGrave

    Intervention: The concomitant use of fenoprofen with other NSAIDs or salicylates is not recommended. (bula de Fenoprofeno, Interações medicamentosas)

  • Fisostigminainibidor da colinesteraseGrave

    Contraindications: ANTICHOLIUM ® should not be used in the presence of hypersensitivity to physostigmine salicylate, bronchial asthma, ulcers associated with tissue destruction (gangrene), coronary heart disease, constipation (mechanical obstipation), mechanical ischuria (urinary retention), hereditary form of muscle atrophy (myotonic dystrophy), closed traumatic… (bula de Fisostigmina, Contraindicações)

  • FlurbiprofenoAINEGrave

    Intervention: The concomitant use of flurbiprofen with other NSAIDs or salicylates is not recommended. (bula de Flurbiprofeno, Interações medicamentosas)

  • Fosinopril + hidroclorotiazidainibidor da ECAGrave

    Fosinopril sodium and hydrochlorothiazide is also contraindicated in patients who are hypersensitive to fosinopril, to any other ACE inhibitor, to hydrochlorothiazide, or other sulfonamide-derived drugs, or any other ingredient or component in the formulation. (bula de Fosinopril + hidroclorotiazida, Contraindicações)

  • GlimepiridasulfonilureiaGrave

    • Sulfonamide derivatives: Patients who have developed an allergic reaction to sulfonamide derivatives may develop an allergic reaction to glimepiride tablets.Do not use glimepiride tablets in patients who have a history of an allergic reaction to sulfonamide derivatives. (bula de Glimepirida, Contraindicações)

  • GlipizidasulfonilureiaGrave

    • Hypersensitivity to sulfonamide derivatives. ▪ Known hypersensitivity to glipizide or any of the product's ingredients ( 4 ). ▪ Hypersensitivity to sulfonamide derivatives ( 4 ). (bula de Glipizida, Contraindicações)

  • Hidroclorotiazidadiurético tiazídicoGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (bula de Hidroclorotiazida, Contraindicações)

  • The concomitant use of ibuprofen with other NSAIDs or salicylates is not recommended. (bula de Hidrocodona + ibuprofeno, Interações medicamentosas)

  • IbuprofenoAINEGrave

    Intervention: The concomitant use of ibuprofen with other NSAIDs or salicylates is not recommended. (bula de Ibuprofeno, Interações medicamentosas)

  • Intervention: The concomitant use of ibuprofen and famotidine tablet with other NSAIDs or salicylates is not recommended. (bula de Ibuprofeno + famotidina, Interações medicamentosas)

  • Indapamidadiurético tiazídicoGrave

    Known hypersensitivity to indapamide or to other sulfonamide-derived drugs. (bula de Indapamida, Contraindicações)

  • IndometacinaAINEGrave

    Intervention: The concomitant use of indomethacin with other NSAIDs or salicylates, especially diflunisal, is not recommended. (bula de Indometacina, Interações medicamentosas)

  • Irbesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Irbesartana + hidroclorotiazida, Contraindicações)

  • Lisinopril + hidroclorotiazidainibidor da ECAGrave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Lisinopril + hidroclorotiazida, Contraindicações)

  • Mecamilaminaanti-hipertensivoGrave

    Patients receiving antibiotics and sulfonamides should generally not be treated with ganglion blockers. (bula de Mecamilamina, Contraindicações)

  • MeloxicamAINEGrave

    Intervention: The concomitant use of meloxicam with other NSAIDs or salicylates is not recommended. (bula de Meloxicam, Interações medicamentosas)

  • Anuria Hypersensitivity to metoprolol tartrate or hydrochlorothiazide or to other sulfonamide- derived drugs. (bula de Metoprolol + hidroclorotiazida, Contraindicações)

  • NaproxenoAINEGrave

    Intervention: The concomitant use of naproxen with other NSAIDs or salicylates is not recommended. (bula de Naproxeno, Interações medicamentosas)

  • Intervention: The concomitant use of naproxen and esomeprazole magnesium delayed-release tablets with other NSAIDs or salicylates is not recommended. (bula de Naproxeno + esomeprazol, Interações medicamentosas)

  • Olmesartana + anlodipino + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    Because of the hydrochlorothiazide component, olmesartan medoxomil, amlodipine and hydrochlorothiazide tablet is contraindicated in patients with anuria, hypersensitivity to any component, or hypersensitivity to other sulfonamide-derived drugs. (bula de Olmesartana + anlodipino + hidroclorotiazida, Contraindicações)

  • OxaprozinaAINEGrave

    Intervention: The concomitant use of oxaprozin with other NSAIDs or salicylates is not recommended. (bula de Oxaprozina, Interações medicamentosas)

  • Intervention: The concomitant use of ibuprofen with other NSAIDs or salicylates is not recommended. (bula de Paracetamol + ibuprofeno, Interações medicamentosas)

  • Pioglitazona + glimepiridatiazolidinedionaGrave

    Use in patients with known history of an allergic reaction to sulfonamide derivatives. (bula de Pioglitazona + glimepirida, Contraindicações)

  • PiroxicamAINEGrave

    Intervention: The concomitant use of piroxicam with other NSAIDs or salicylates is not recommended. (bula de Piroxicam, Interações medicamentosas)

  • In patients on probenecid the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (bula de Probenecida, Advertências)

  • In patients on probenecid and colchicine the use of salicylates in either small or large doses is contraindicated because it antagonizes the uricosuric action of probenecid. (bula de Probenecida + colchicina, Advertências)

  • Quinapril + hidroclorotiazidainibidor da ECAGrave

    Because of the hydrochlorothiazide components, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Quinapril + hidroclorotiazida, Contraindicações)

  • Sepiapterin Reductase (SR) Inhibitors : Avoid concomitant use (e.g. sulfasalazine or sulfamethoxazole). (bula de Sepiapterina, Interações medicamentosas)

  • Coadministration of VOSEVI with BCRP substrates (e.g., methotrexate, mitoxantrone, imatinib, irinotecan, lapatinib, rosuvastatin, sulfasalazine, topotecan) is not recommended [see Clinical Pharmacology (12.3) ]. (bula de Sofosbuvir + velpatasvir, Interações medicamentosas)

  • Intervention: The concomitant use of naproxen with other NSAIDs or salicylates is not recommended. (bula de Sumatriptana + naproxeno, Interações medicamentosas)

  • TansulosinaalfabloqueadorGrave

    If a patient reports a serious or life-threatening sulfa allergy, caution is warranted when administering tamsulosin hydrochloride capsules. (bula de Tansulosina, Advertências e precauções)

  • Triantereno + hidroclorotiazidadiurético poupador de potássioGrave

    Hypersensitivity Hypersensitivity to either drug in the preparation or to other sulfonamide-derived drugs is a contraindication. (bula de Triantereno + hidroclorotiazida, Contraindicações)

  • Valsartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Grave

    Because of the hydrochlorothiazide component, this product is contraindicated in patients with anuria or hypersensitivity to other sulfonamide-derived drugs. (bula de Valsartana + hidroclorotiazida, Contraindicações)

Interações moderadas (65)

  • Ácido fólico (folato)Vitaminas e mineraisModerada

    Drug Interactions: Reduced absorption of folic acid and digoxin have been reported when those agents were administered concomitantly with sulfasalazine. (bula de Sulfassalazina, Interações medicamentosas)

  • AdapalenoretinoideModerada

    Particular caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid in combination with Adapalene Cream, 0.1%. (bula de Adapaleno, Interações medicamentosas)

  • AlmotriptanatriptanoModerada

    Use with caution in patients with a known hypersensitivity to sulfonamides ( 5.8 ) (bula de Almotriptana, Advertências e precauções)

  • Articaína + epinefrinaanestésico localModerada

    …nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine Monoamine Oxidase Inhibitors, Nonselective Beta-Adrenergic Antagonists, or Tricyclic Antidepressants: May produce severe, prolonged hypertension ( 7 ) (bula de Articaína + epinefrina, Interações medicamentosas)

  • Brinzolamidainibidor da anidrase carbônicaModerada

    • Rare instances of acid-base alterations have occurred with high-dose salicylate therapy. (bula de Brinzolamida, Interações medicamentosas)

  • Bromocriptinaagonista da dopaminaModerada

    Therefore, CYCLOSET may increase the unbound fraction of other concomitantly used highly protein-bound therapies (e.g., salicylates, sulfonamides, chloramphenicol and probenecid), which may alter their effectiveness and risk for side effects. (bula de Bromocriptina, Interações medicamentosas)

  • Bupivacaína + epinefrinaanestésico localModerada

    …para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent Inhalation Anesthetics Serious dose-related cardiac arrhythmias may occur if preparations containing a vasoconstrictor such as epinephrine (e.g., MARCAINE WITH… (bula de Bupivacaína + epinefrina, Interações medicamentosas)

  • CetorolacoAINEModerada

    Warfarin, Digoxin, Salicylate, and Heparin The in vitro binding of warfarin to plasma proteins is only slightly reduced by ketorolac tromethamine (99.5% control vs 99.3%) when ketorolac plasma concentrations reach 5 to 10 mcg/mL. (bula de Cetorolaco, Interações medicamentosas)

  • CiprofloxacinofluoroquinolonaModerada

    NSAIDs Use with caution Non-steroidal anti-inflammatory drugs (but not acetyl salicylic acid) in combination of very high doses of quinolones have been shown to provoke convulsions in pre-clinical studies and in postmarketing. (bula de Ciprofloxacino, Interações medicamentosas)

  • DarunavirantirretroviralModerada

    Use with caution in patients with a known sulfonamide allergy. (bula de Darunavir, Advertências e precauções)

  • Darunavir + cobicistateantirretroviralModerada

    Monitor in patients with a known sulfonamide allergy. (bula de Darunavir + cobicistate, Advertências e precauções)

  • Desogestrel + etinilestradiolanticoncepcional oralModerada

    COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (bula de Desogestrel + etinilestradiol, Interações medicamentosas)

  • DexametasonacorticosteroideModerada

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (bula de Dexametasona, Interações medicamentosas)

  • Digoxinaglicosídeo digitálicoModerada

    Drug Interactions: Reduced absorption of folic acid and digoxin have been reported when those agents were administered concomitantly with sulfasalazine. (bula de Sulfassalazina, Interações medicamentosas)

  • Dorzolamidainibidor da anidrase carbônicaModerada

    High-Dose Salicylate Therapy Although acid-base and electrolyte disturbances were not reported in the clinical trials with dorzolamide hydrochloride ophthalmic solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associated with high-dose salicylate therapy). (bula de Dorzolamida, Interações medicamentosas)

  • Dorzolamida + timololinibidor da anidrase carbônicaModerada

    High-Dose Salicylate Therapy Although acid-base and electrolyte disturbances were not reported in the clinical trials with dorzolamide hydrochloride ophthalmic solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associated with high-dose salicylate therapy). (bula de Dorzolamida + timolol, Interações medicamentosas)

  • Eltrombopagueinibidor do OATP1B1Moderada

    …(e.g., atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin, repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin, sulfasalazine, topotecan). (bula de Eltrombopague, Interações medicamentosas)

  • EtanercepteimunossupressorModerada

    Sulfasalazine Patients in a clinical study who were on established therapy with sulfasalazine, to which Enbrel was added, were noted to develop a mild decrease in mean neutrophil counts in comparison to groups treated with either Enbrel or sulfasalazine alone. (bula de Etanercepte, Interações medicamentosas)

  • CHCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid and temazepam. (bula de Etonogestrel + etinilestradiol, Interações medicamentosas)

  • Hyperventilation and Metabolic Acidosis: Sodium Phenylacetate and Sodium Benzoate Injection may cause side effects typically associated with salicylate overdose, such as hyperventilation and metabolic acidosis. (bula de Fenilacetato de sódio + benzoato de sódio, Advertências e precauções)

  • FenitoínaanticonvulsivanteModerada

    …voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine, sulfamethoxazole-trimethoprim Other Acute alcohol intake, amiodarone, chloramphenicol, chlordiazepoxide, disulfiram, estrogen,… (bula de Fenitoína, Interações medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Rarely salicylate toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. (bula de Fludrocortisona, Interações medicamentosas)

  • FosamprenavirantirretroviralModerada

    Fosamprenavir calcium should be used with caution in patients with a known sulfonamide allergy. (bula de Fosamprenavir, Advertências e precauções)

  • FosfenitoínaanticonvulsivanteModerada

    …voriconazole Antineoplastic agents Capecitabine, fluorouracil Antidepressants Fluoxetine, fluvoxamine, sertraline Gastric acid reducing agents H 2 antagonists (cimetidine), omeprazole Sulfonamides Sulfamethizole, sulfaphenazole, sulfadiazine, sulfamethoxazole-trimethoprim Other Acute alcohol intake, amiodarone, chloramphenicol, chlordiazepoxide, disulfiram, estrogen,… (bula de Fosfenitoína, Interações medicamentosas)

  • Furosemidadiurético de alçaModerada

    • Salicylates : Risk of salicylate toxicity ( 7.1 ) (bula de Furosemida, Interações medicamentosas)

  • GlibenclamidasulfonilureiaModerada

    …Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents, ACE inhibitors, disopyramide, fluoxetine, clarithromycin, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, monoamine oxidase inhibitors, and beta adrenergic blocking agents. (bula de Glibenclamida, Interações medicamentosas)

  • Glipizida + metforminasulfonilureiaModerada

    Glipizide: The hypoglycemic action of sulfonylureas may be potentiated by certain drugs, including nonsteroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, and beta-adrenergic blocking agents. (bula de Glipizida + metformina, Precauções)

  • GriseofulvinaantifúngicoModerada

    Serum salicylate concentrations may be decreased when griseofulvin is given concomitantly with salicylates. (bula de Griseofulvina, Interações medicamentosas)

  • • Large doses of salicylates, cortisone, adrenocorticotropic hormone (ACTH), estrogens or antihistamines may require larger amounts of hyaluronidase for equivalent dispersing effect ( 7.4 ) (bula de Hialuronidase, Interações medicamentosas)

  • HidrocortisonacorticosteroideModerada

    The clearance of salicylates may be increased with concurrent use of corticosteroids; this could lead to decreased salicylate serum levels or increase the risk of salicylate toxicity when corticosteroid is withdrawn. (bula de Hidrocortisona, Interações medicamentosas)

  • Insulina asparteinsulinaModerada

    Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics. (bula de Insulina asparte, Interações medicamentosas)

  • Insulina degludecainsulinaModerada

    …May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, SGLT-2 inhibitors. (bula de Insulina degludeca, Interações medicamentosas)

  • Insulina detemirinsulinaModerada

    …May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, SGLT-2 inhibitors. (bula de Insulina detemir, Interações medicamentosas)

  • Insulina glarginainsulinaModerada

    …May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors. (bula de Insulina glargina, Interações medicamentosas)

  • Insulina lisproinsulinaModerada

    Clinically Significant Drug Interactions with LYUMJEV Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (bula de Insulina lispro, Interações medicamentosas)

  • …Receptor Blocking Agents, Disopyramide, Fibrates, Fluoxetine, Monoamine Oxidase Inhibitors, Pentoxifylline, Pramlintide, Salicylates, Somatostatin Analogs (e.g., octreotide), and Sulfonamide Antibiotics Prevention or Management Monitor blood glucose more frequently and modify AFREZZA dosage, as clinically indicated, when used concomitantly with these drugs. (bula de Insulina regular (humana), Interações medicamentosas)

  • Levonorgestrel + etinilestradiolanticoncepcional oralModerada

    Other Drugs Clinical effect Concomitant use of CHCs may decrease systemic exposure of acetaminophen, morphine, salicylic acid, and temazepam. (bula de Levonorgestrel + etinilestradiol, Interações medicamentosas)

  • Levotiroxinahormônio tireoidianoModerada

    An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (bula de Levotiroxina, Interações medicamentosas)

  • Lidocaína + epinefrinaanestésico localModerada

    …para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine 7.6 Potent Inhalation Anesthetics Serious dose-related cardiac arrhythmias may occur if preparations containing epinephrine are used in patients during or following the… (bula de Lidocaína + epinefrina, Interações medicamentosas)

  • Lidocaína + prilocaínaanestésico localModerada

    …prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, isofamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sufonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (bula de Lidocaína + prilocaína, Interações medicamentosas)

  • Liotironinahormônio tireoidianoModerada

    An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%. (bula de Liotironina, Interações medicamentosas)

  • Losartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Losartana + hidroclorotiazida, Advertências e precauções)

  • Mepivacaínaanestésico localModerada

    …procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine (bula de Mepivacaína, Interações medicamentosas)

  • MercaptopurinaantimetabólitoModerada

    Aminosalicylates Aminosalicylates (e.g., mesalamine, olsalazine or sulfasalazine) may inhibit the TPMT enzyme, which may increase the risk of myelosuppression when coadministered with mercaptopurine tablets. (bula de Mercaptopurina, Interações medicamentosas)

  • MetilprednisolonacorticosteroideModerada

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (bula de Metilprednisolona, Interações medicamentosas)

  • Metolazonadiurético tiazídicoModerada

    Salicylates And Other Non-Steroidal Anti-Inflammatory Drugs May decrease the antihypertensive effects of metolazone tablets, USP. (bula de Metolazona, Interações medicamentosas)

  • MetotrexatoimunossupressorModerada

    When daily doses of sulfasalazine 2 g and weekly doses of methotrexate 7.5 mg were coadministered to 15 rheumatoid arthritis patients in a drug-drug interaction study, the pharmacokinetic disposition of the drugs was not altered. (bula de Sulfassalazina, Interações medicamentosas)

  • NateglinidameglitinidaModerada

    …with Nateglinide Drugs That May Increase the Blood-Glucose-Lowering Effect of Nateglinide and Susceptibility to Hypoglycemia Drugs: Nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, monoamine oxidase inhibitors, non-selective beta-adrenergic-blocking agents, anabolic hormones (e.g., methandrostenolone), guanethidine, gymnema sylvestre, glucomannan,… (bula de Nateglinida, Interações medicamentosas)

  • Nizatidinabloqueador H2Moderada

    In patients given very high doses (3,900 mg) of aspirin daily, increases in serum salicylate levels were seen when nizatidine, 150 mg b.i.d., was administered concurrently. (bula de Nizatidina, Interações medicamentosas)

  • CHCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, and temazepam. (bula de Norelgestromina + etinilestradiol, Interações medicamentosas)

  • Norgestimato + etinilestradiolanticoncepcional oralModerada

    COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (bula de Norgestimato + etinilestradiol, Interações medicamentosas)

  • Norgestrel + etinilestradiolanticoncepcional oralModerada

    COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine. (bula de Norgestrel + etinilestradiol, Interações medicamentosas)

  • Olmesartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Olmesartana + hidroclorotiazida, Advertências e precauções)

  • PirimetaminaantimaláricoModerada

    However, the concomitant use of other antifolic drugs or agents associated with myelosuppression including sulfonamides or trimethoprim- sulfamethoxazole combinations, proguanil, zidovudine, or cytostatic agents (e.g., methotrexate), while the patient is receiving pyrimethamine, may increase the risk of bone marrow suppression. (bula de Pirimetamina, Interações medicamentosas)

  • PrednisolonacorticosteroideModerada

    NSAIDS, including aspirin and salicylates: Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects. (bula de Prednisolona, Interações medicamentosas)

  • PrednisonacorticosteroideModerada

    NSAIDs including aspirin and salicylates: Increased risk of gastrointestinal side effects. (bula de Prednisona, Interações medicamentosas)

  • Prilocaína + epinefrinaanestésico localModerada

    …para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine The administration of local anesthetic injections containing epinephrine or norepinephrine to patients receiving monoamine oxidase inhibitors, tricyclic antidepressants… (bula de Prilocaína + epinefrina, Interações medicamentosas)

  • Ropivacaínaanestésico localModerada

    …para-aminosalicylic acid, sulfonamides Antimalarials chloroquine, primaquine Anticonvulsants Phenobarbital, phenytoin, sodium valproate Other drugs acetaminophen, metoclopramide, quinine, sulfasalazine NAROPIN should be used with caution in patients receiving other local anesthetics or agents structurally related to amide- type local anesthetics, since the toxic effects… (bula de Ropivacaína, Interações medicamentosas)

  • SalsalatoAINEModerada

    ASPIRIN AND OTHER SALICYLATE DRUGS WILL BE ADDITIVE TO SALSALATE AND MAY INCREASE PLASMA CONCENTRATIONS OF SALICYLIC ACID TO TOXIC LEVELS. (bula de Salsalato, Interações medicamentosas)

  • SulfadiazinasulfonamidaModerada

    Conversely, agents such as indomethacin, probenecid and salicylates may displace sulfonamides from plasma albumin and increase the concentrations of free drug in plasma. (bula de Sulfadiazina, Interações medicamentosas)

  • Like other sulfonamide-containing drugs, sulfamethoxazole and trimethoprim potentiates the effect of oral hypoglycemics. (bula de Sulfametoxazol + trimetoprima, Interações medicamentosas)

  • Telmisartana + hidroclorotiazidabloqueador do receptor da angiotensina II (BRA)Moderada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (bula de Telmisartana + hidroclorotiazida, Advertências e precauções)

  • Torasemidadiurético de alçaModerada

    Nonsteroidal Anti-Inflammatory Drugs Because torsemide and salicylates compete for secretion by renal tubules, patients receiving high doses of salicylates may experience salicylate toxicity when torsemide is concomitantly administered. (bula de Torasemida, Interações medicamentosas)

  • TriancinolonacorticosteroideModerada

    The clearance of salicylates may be increased with concurrent use of corticosteroids. (bula de Triancinolona, Interações medicamentosas)

  • VortioxetinaantidepressivoModerada

    Coadministration of aspirin 150 mg/day with multiple daily doses of TRINTELLIX had no significant inhibitory effect on platelet aggregation or pharmacokinetics of aspirin and salicylic acid [see Clinical Pharmacology (12.3) ] . (bula de Vortioxetina, Interações medicamentosas)

Menções leves (14)

  • Amoxicilinaantibiótico da classe das penicilinasLeve

    Other Antibacterials Chloramphenicol, macrolides, sulfonamides, and tetracyclines may interfere with the bactericidal effects of penicillin. (bula de Amoxicilina, Interações medicamentosas)

  • Ampicilinaantibiótico da classe das penicilinasLeve

    Bacteriostatic Antibiotics : Chloramphenicol, erythromycins, sulfonamides, or tetracyclines may interfere with the bactericidal effect of penicillins. (bula de Ampicilina, Interações medicamentosas)

  • Azul de metilenoinibidor da MAOLeve

    Lack of Effectiveness Methemoglobinemia may not resolve or may rebound after response to treatment with PROVAYBLUE in patients with methemoglobinemia due to aryl amines such as aniline or sulfa drugs such as dapsone. (bula de Azul de metileno, Advertências e precauções)

  • BalsalazidasalicilatoLeve

    Although the exact frequency of occurrence has not been determined, it has occurred in 3% of patients in controlled clinical trials of mesalamine or sulfasalazine. (bula de Balsalazida, Advertências e precauções)

  • Benzilpenicilina (penicilina G)antibiótico da classe das penicilinasLeve

    Drug Interactions Bacteriostatic antibacterials ( i.e. , chloramphenicol, erythromycins, sulfonamides or tetracyclines) may antagonize the bactericidal effect of penicillin, and concurrent use of these drugs should be avoided. (bula de Benzilpenicilina (penicilina G), Interações medicamentosas)

  • Bumetanidadiurético de alçaLeve

    Allergy to Sulfonamides Patients allergic to sulfonamides may show hypersensitivity to bumetanide. (bula de Bumetanida, Advertências)

  • EnoxaparinaanticoagulanteLeve

    These agents include medications such as: anticoagulants, platelet inhibitors including acetylsalicylic acid, salicylates, NSAIDs (including ketorolac tromethamine), dipyridamole, or sulfinpyrazone. (bula de Enoxaparina, Interações medicamentosas)

  • In vitro studies have shown no binding displacement between entacapone and other highly bound drugs, such as warfarin, salicylic acid, phenylbutazone, and diazepam. (bula de Entacapona, Precauções)

  • Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole. (bula de Glibenclamida + metformina, Interações medicamentosas)

  • MesalazinasalicilatoLeve

    Although the exact frequency of occurrence has not been determined, it has occurred in 3% of patients in controlled clinical trials of mesalamine or sulfasalazine. (bula de Mesalazina, Advertências e precauções)

  • RepaglinidameglitinidaLeve

    Examples: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, nonsteroidal anti-inflammatory agents (NSAIDs), pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. (bula de Repaglinida, Interações medicamentosas)

  • Hepatotoxic Drugs Clinical trials in ALS patients excluded patients on concomitant medications which were potentially hepatotoxic (e.g., allopurinol, methyldopa, sulfasalazine). (bula de Riluzol, Interações medicamentosas)

  • Sulfadiazina de pratasulfonamidaLeve

    There is a potential cross-sensitivity between silver sulfadiazine and other sulfonamides. (bula de Sulfadiazina de prata, Advertências e precauções)

  • Zileutonainibidor da CYP1A2Leve

    Drug-drug interaction studies in healthy subjects have been conducted with zileuton immediate-release tablets and digoxin, phenytoin, sulfasalazine, and naproxen. (bula de Zileutona, Interações medicamentosas)

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