التداخل بين بوتورفانول ونيفيديبين

The interaction with high-dose fentanyl appears to be due to the combination of nifedipine and a beta-blocker, but the possibility that it may occur with nifedipine alone, with low doses of fentanyl, in other surgical procedures, or with other narcotic analgesics cannot be ruled out.

In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs.