التداخل بين كالسيتريول وكيتوكونازول

Reductions in serum endogenous calcitriol concentrations have been observed following the administration of 300 mg/day to 1200 mg/day ketoconazole for a week to healthy men.

Ketoconazole Ketoconazole may inhibit both synthetic and catabolic enzymes of calcitriol.

However, in vivo drug interaction studies of ketoconazole with calcitriol have not been investigated.