التداخل بين دوكسيلامين وبيريدوكسين وبنسيلامين

Patients with Wilson’s disease or cystinuria should be given 25 mg/day of pyridoxine during therapy, since penicillamine increases the requirement for this vitamin.

Patients also may receive benefit from a multivitamin preparation, although there is no evidence that deficiency of any vitamin other than pyridoxine is associated with penicillamine.

Rheumatoid arthritis patients whose nutrition is impaired should also be given a daily supplement of pyridoxine.

Pruritus and early rash may often be controlled by the concomitant administration of antihistamines.