التداخل بين إيثينوديول ثنائي الأسيتات وإيثينيل إستراديول وتيرزيباتيد

Advise patients using oral hormonal contraceptives to switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after initiation with ZEPBOUND and for 4 weeks after each dose escalation.

Hormonal contraceptives that are not administered orally should not be affected [see Use in Specific Populations ( 8.3 ) and Clinical Pharmacology ( 12.2 , 12.3 )] .

Progestogens increase insulin secretion and create insulin resistance, the effect varying with different progestational agents.